• Title/Summary/Keyword: immunoglobulins

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The Effect of High Hydrostatic Pressure Treatment on the Preservability and the Immunological Activity of Bovine Colostrum

  • Masuda, T.;Rehinarudo, H.Y.;Suzuki, K.;Sakai, T.;Morichi, T.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.9
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    • pp.1323-1328
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    • 2000
  • Bovine colostrum, which contains a large quantity of immunoglobulins, is indispensable for newborn animals. The establishment of a new procedure for preserving colostrum without losing the immunological activity is significant. We examined the effect of high hydrostatic pressure treatment (100~500 MPa) on the preservability and the immunochemical activity of bovine colostrum. When high hydrostatic pressure treatment was 300 MPa or more, the increase of the total viable count, coliforms and psychrotrophic gram-negative bacteria was suppressed effectively. In particular, the number of coliforms in colostrum treated at 300 MPa or more hardly increased for 35 days at $4{^{\circ}C}$. At 400 MPa or more, both gelling of the colostrum and denaturation of immunoglobulins were observed. However, if the pressure was 300 MPa, immunoglobulins were scarcely influenced and the neutralizing titers against the bovine coronavirus did not decrease. Therefore, it was suggested that 300 MPa was the best pressure for good preservability of colostrum without reducing the immunochemical response.

Hot environment on reproductive performance, immunoglobulins, vitamin E, and vitamin A status in sows and their progeny under commercial husbandry

  • Amavizca-Nazar, Alejandra;Montalvo-Corral, Maricela;Gonzalez-Rios, Humberto;Pinelli-Saavedra, Araceli
    • Journal of Animal Science and Technology
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    • v.61 no.6
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    • pp.340-351
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    • 2019
  • Hot environments can affect feed intake and lactation, and the subsequent unavailability of important micronutrients to the newborn piglet can impair piglet growth, reduce the viability of newborn piglets and limit their subsequent performance. This work addresses the effects of hot environments (summer season) upon the reproductive performance of sows during gestation and lactation as well as on the serum levels of vitamins and the concentration of immunoglobulins in their litters in comparison with the winter season. Fourteen sows were evaluated over 100 ± 2 days of gestation in each season. The temperature and humidity index (THI) was used as an indirect measure of heat stress during gestation. The reproductive performance, milk yield, and body condition of the sows were recorded. The concentrations of vitamin E and vitamin A in piglets and in sow serum, colostrum, milk and feed were determined by HPLC; immunoglobulins were assessed by an ELISA. The THI index indicated that animals were subject to heat stress only in during the summer. Although the effect was not significant, there were a lower number of piglets at birth and at weaning and the milk yield in summer compared with winter. There was no difference (p > 0.05) in the body condition of sows between seasons. Season had an effect (p < 0.05) on the vitamin A concentration of postpartum sow serum (0.29 ㎍/mL in winter vs 0.21 ㎍/mL in summer) and on the vitamin E concentration before birth (2.00 ㎍/mL in winter vs 0.90 ㎍/mL in summer). Vitamin E in milk was higher (p < 0.05) in winter than in summer (2.23 vs 1.81 ㎍/mL). Serum levels of vitamins A and E in piglets at birth were lower (p < 0.05) in winter than in summer. The concentrations of immunoglobulins (IgG and IgA) in colostrum and milk were similar between seasons (p > 0.05), but the IgA in piglet serum was higher in winter than in summer (p < 0.05). High temperatures produced heat stress in sows, which affected certain aspects of production that can be translated into economic losses for this sector.

Differential Cytokine and Immunoglobulin Expressions in the Small Intestine of Echinostoma hortense Infected BALB/c Mice

  • Jo, Yoon-Kyung;Lee, Dong-Sup;Kim, Sung-In;Lee, Ji-Sook;Oh, Ji-Eun;Sung, Ho-Joong
    • Biomedical Science Letters
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    • v.18 no.3
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    • pp.254-259
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    • 2012
  • Infections involving Echinostoma hortense (E. hortense) are considered to more severe than infections caused by other heterophyids. Although parasite expulsion by host immune responses attenuates the symptoms of infection, the detailed mechanisms of the host immune response need to be determined, especially in local immune responses involving cytokine and immunoglobulin expressions. We infected BALB/c mice with E. hortense and examined recovery rates together with expressions of multiple cytokines and immunoglobulins in the villi and crypts of the small intestine using immunohistochemistry. We observed a close correlation between worm expulsion rates and cytokine/immunoglobulin expressions in E. hortense infected mice. This study contributes to an understanding of the relationship between the immune response and parasite expulsion in hosts.

Bilateral Optic Neuritis after Measles Infection (홍역 감염 후 발생한 양측성 시신경염 1례)

  • Hwang, Sung Hyun;Kim, Jong-Hyun;Oh, Jin Hee;Koh, Dae Kyun
    • Pediatric Infection and Vaccine
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    • v.11 no.2
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    • pp.192-197
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    • 2004
  • A 9-year-old boy who was confirmed measles by clinical manifestations and serum measles IgM antibody presented with bilateral visual loss 12 days after the onset of maculopapular rash. Complete ophthalmic and neurologic examinations, radiologic studies, and lumbar puncture were performed. Visual acuities were counting fingers in both eyes, with mild bilateral optic disk hyperemia and swelling noted. Neurologic examination was unremarkable, however, a magnetic resonance imaging of the brain showed high signals on basal ganglia, and periventricular white matter. The cerebrospinal fluid was devoid of white cells. Intravenous methylprednisolone and high dose immunoglobulins were administered, and clinical findings resolved completely within 6 months.

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Resistance of Hen항s Egg Yolk Immunoglobulins in Livetin to Digestive Enzymes (리베틴에 존재하는 난황항제의 소화효소에 대한 저항성)

  • 이경애
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.28 no.2
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    • pp.438-443
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    • 1999
  • A livetin solution(LS) containing yolk immunoglobulins(IgY) was separated by treating the egg yolk with natural gum, carrageenan. Carrageenan has been used as a food ingredient. Relative absorbance of IgY LS after proteolysis was investigated. IgY LS was fairly stable to pepsin digestion at pH 3.0. However, IgY LS appeared to be susceptible to pepsin digestion at pH 2.0, showing 18% of relative absorbance and complete breakdown H chain after 30 min exposure. Relative absorbance of IgY LS was considerably high after exposure to trypsin and chymotrypsin for 8 hr. IgY LS showed especially good stability to chymotrypsin digestion.

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Changes of Plasma Immunoglobulins and Complements after Extracorporeal Circulation (체외순환후 혈청내 Immunoglobulin 과 보체의 변화에 관한 연구 - 막형 인공산화기와 기포형 인공산화기의 비교 -)

  • 이철주
    • Journal of Chest Surgery
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    • v.21 no.4
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    • pp.613-618
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    • 1988
  • The exposure of blood to foreign materials can cause the denaturation of plasma protein components such as immunoglobulins and complements. And those phenomena increase the morbidity and mortality after intracardiac operations through the cardiopulmonary bypass. From April, 1987 to September, 1987, we had observed the serial changes of plasma total protein IgG, IgA, IgM, complements[C3, C4] in bubble oxygenator group[n=5] and membrane oxygenator group[n=5]. Statistically significant difference between two groups were present in total protein and C3. We conclude that using membrane oxygenator in long extracorporeal circulation can reduce the activation of alternative pathway of complement system, and which can reduce post-perfusion complications of the lung though we can`t prove it in mass populations.

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