• 대한한방내과학회지
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• 제28권4호
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• pp.850-862
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• 2007

Background : Cerebrovascular disease is a major cause of death and disability in adults. Silent cerebral infarction (SCI) portends more severe cerebral infarction or may lead to insidious progressive brain damage resulting in vascular dementia. Known cardiovascular risk factors, such as arterial hypertension, diabetes mellitus, smoking, hyperlipidemia and ischemic heart disease may increase the risk of SCI. This study was designed to evaluate the risk factors of SCI in an apparently normal adult population. Methods : We divided 340 neurologically normal adults (mean age=59.90$\pm$8.30, men:women = 146:194) who underwent brain computed tomography (CT) or magnetic resonance imaging (MRI) at the Stroke Medical Center in Daejeon University Oriental Medicine Hospital in two groups, Silent inf. and Controls,and analyzed risk factors of SCI by interview, physical examination and blood test. Risk factors of SCI were assessed by interview, physical examination and blood test. We performed Pearson's chi-square test and two-sample t-test for univariate analysis and multiple logistic regressions for multivariate analysis to evaluate risk factors of SCI. Results : Old age, diabetes mellitus, and high lactate dehydrogenase (LDH) levels were associated with SCI on univariate analysis. Diabetes mellitus was demonstrated to be an independent risk factor for SCI on multivariate analysis. Conclusions : Advanced age, diabetes mellitus, and LDH levels are associated with SCI.

• Journal of Chest Surgery
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• 제41권5호
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• pp.667-670
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• 2008

성인에서의 잠복 기관지 이물은 소아의 기관지내 이물 흡인과 달리 매우 드물며 아직까지 기관지나 폐의 연관손상 정도와 잠복기간에 따른 치료전략이 정립되어 있지 않은 상태다. 과거력상 반복적인 기침과 객담, 발열을 경험하였으나 30년 전에 사인펜 뚜껑이 기도내로 흡인되었던 사실을 인지하지 못하던 40세 남자 환자가 동일 주소와 영상검사상 우중엽 및 하엽의 허탈과 폐쇄성 폐간질염 소견으로 전원되었다. 처음엔 기관지경 이물 제거와 내과적 치료를 계획하였으나 제거가 불가능하였고 결국 개흉후 양엽 절제를 통해 치료하였다. 저자들은 본 증례가 잠복성 기관지 이물의 다양한 임상상 축적에 중요한 정보를 제공하였다고 생각한다.

• 한국농공학회논문집
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• 제62권3호
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• pp.51-61
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• 2020

Drought events are not clear when those start and end compared with other natural disasters. Because drought events have different timing and severity of damage depending on the region, various studies are being conducted using satellite images to identify regional drought occurrence differences. In this study, we investigated the applicability of drought assessment using the Evaporative Stress Index (ESI) based on Moderate Resolution Imaging Spectroradiometer (MODIS) satellite images. The ESI is an indicator of agricultural drought that describes anomalies in actual and reference evapotranspiration (ET) ratios that are retrieved using remotely sensed inputs of Land Surface Temperature (LST) and Leaf Area Index (LAI). However, these approaches have a limited spatial resolution when mapping detailed vegetation stress caused by drought, and drought hazard in the actual crop cultivation areas due to the small crop cultivation in South Korea. For these reasons, the development of a drought index that provides detailed higher resolution ESI, a 500 m resolution image is essential to improve the country's drought monitoring capabilities. The newly calculated ESI was verified through the existing 5 km resolution ESI and historical records for drought impacts. This study evaluates the performance of the recently developed 500 m resolution ESI for severe and extreme drought events that occurred in South Korea in 2001, 2009, 2014, and 2017. As a result, the two ES Is showed high correlation and tendency using Receiver Operating Characteristics (ROC) analysis. In addition, it will provide the necessary information on the spatial resolution to evaluate regional drought hazard assessment and and the small-scale cultivation area across South Korea.

• Journal of Korean Neurosurgical Society
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• 제57권5호
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• pp.367-370
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• 2015

Bone cement augmentation procedures have been getting more position as a minimally invasive surgical option for osteoporotic spinal fractures. However, complications related to these procedures have been increasingly reported. We describe a case of bone cement dislodgement following cement augmentation procedure for osteoporotic spinal fracture by reviewing the patient's medical records, imaging results and related literatures. A 73-year-old woman suffering back and buttock pain following a fall from level ground was diagnosed as an osteoporotic fracture of the 11th thoracic spine. Percutaneous kyphoplasty was performed for this lesion. Six weeks later, the patient complained of a recurrence of back and buttock pain. Radiologic images revealed superior dislodgement of bone cement through the 11th thoracic superior endplate with destruction of the lower part of the 10th thoracic spine. Staged anterior and posterior fusion was performed. Two years postoperatively, the patient carries on with her daily living without any significant disability. Delayed bone cement dislodgement can occur as one of complications following bone cement augmentation procedure for osteoporotic spinal fracture. It might be related to the presence of intravertebral cleft, lack of interdigitation of bone cement with the surrounding trabeculae, and possible damage of endplate during ballooning procedure.

• 대한방사선기술학회지:방사선기술과학
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• 제12권1호
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• pp.3-16
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• 1989

In order to investigate the in vivo effect of $^{60}Co$ radiation on rabbit liver, the uptake ratio and regional excretory value in hepatocytes and Kupffer cells were estimated during acute and chronic hepatic injuries. The left lobe of liver was irradiated at 15 Gy or 30 Gy with a single dose and subsequent changes were analysed with a seial nuclear medicine imaging by using $^{99m}Tc-phytate,\;^{99m}Tc-DISIDA\;and\;^{99m}Tc-HSA$ and resulting data were computerized. The degree of hepatic damage, duration of the injury, and recovery pattern after the irradation were in agreement with the findings of other investigations. However, out values were more quantitative evacuation than those of other publications. Recovery of decreased uptake of $^{99m}Tc-phytate$ was delayed approximately $2{\sim}3$ days later than that of $^{99m}Tc-DISIDA$. In acute radiation induced injury, the results demonstrated that the recovery of Kupffer cells was delayed more than that of hepatocytes. This discrepancy was considered due to the differences in repair activities between these cell types. The decreased of regional excretory value in irradiated area was found to be dose-dependent but had no corelation with regional uptakes of DISIDA and phytate. The decreased of regional excretory value observed in non-irradiated region suggested that irradiated liver might induce an indirect effect.

• 한국방재학회 논문집
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• 제10권6호
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• pp.45-52
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• 2010

사면붕괴로 인한 피해를 최소화하기 위한 방법 중 하나는 사면의 변위발생을 계측하고 붕괴를 예측하여 사전에 방재대책을 수립하는 것이다. 이를 위해 다양한 계측장비들을 활용하여 붕괴를 예측할 수 있는 기술들이 개발되고 있다. 특히 최근에는 사면의 변위발생을 계측하기 위해 첨단 촬영 장비인 지상라이다를 활용하려는 노력이 시도되고 있다. 지상 LiDAR는 수백 미터의 거리에서도 수 mm의 정확도로 대상물의 3차원 정보를 획득 할 수 있기 때문에 문화재 복원, 3차원 모델링, 지형도 작성 등 다양한 분야에서 활용되고 있으며 최근에는 구조물의 변위계측에도 활용되고 있다. 본 연구에서는 이러한 지상라이다를 이용하여 붕괴위험이 높은 위험관리사면을 대상으로 변위 모니터링 수행하였다. 그 결과 지상라이다의 현장적용 가능성을 확인할 수 있었으며 모니터링 방법에 대해 제시할 수 있었다.

• Journal of Korean Neurosurgical Society
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• 제47권3호
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• pp.203-209
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• 2010

Objective : The purpose of study was to evaluate the feasibility of brain magnetic resonance (MR) images of the rat obtained using a 1.5T MR machine in several blood-brain barrier (BBB) experiments. Methods : Male Sprague-Dawley rats were used. MR images were obtained using a clinical 1.5T MR machine. A microcatheter was introduced via the femoral artery to the carotid artery. Normal saline (group 1, n = 4), clotted autologous blood (group 2, n = 4), triolein emulsion (group 3, n = 4), and oleic acid emulsion (group 4, n = 4) were infused into the carotid artery through a microcatheter. Conventional and diffusion-weighted images, the apparent coefficient map, perfusion-weighted images, and contrast-enhanced MR images were obtained. Brain tissue was obtained and triphenyltetrazolium chloride (TTC) staining was performed in group 2. Fluorescein isothiocyanate (FITC)-labeled dextran images and endothelial barrier antigen (EBA) studies were performed in group 4. Results : The MR images in group 1 were of good quality. The MR images in group 2 revealed typical findings of acute cerebral infarction. Perfusion defects were noted on the perfusion-weighted images. The MR images in group 3 showed vasogenic edema and contrast enhancement, representing vascular damage. The rats in group 4 had vasogenic edema on the MR images and leakage of dextran on the FITC-labeled dextran image, representing increased vascular permeability. The immune reaction was decreased on the EBA study. Conclusion : Clinical 1.5T MR images using a rat depicted many informative results in the present study. These results can be used in further researches of the BBB using combined clinical MR machines and immunohistochemical examinations.

• 대한족부족관절학회지
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• 제14권2호
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• pp.119-122
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• 2010

Purpose: One of the main contributors to proximal fifth metatarsal fracture is ankle inversion and the incidence of recurrence may increase in patients with ankle instability. So, the authors confirmed the patients of proximal fifth metatarsal fracture with ankle instability by checking the history and magnetic resonance imaging (MRI) and assessed the value of MRI as therapeutic prognosis and clinical indicators for prevention of recurrence. Materials and Methods: Patients with proximal fifth metatarsal fractures visited our hospital during recent five years were reviewed. 35 patients with suspected damage by ankle inversion had been identified a history of ankle instability and checked the hindfoot malalignment through hindfoot alignment view and MRI was performed prospectively. The patients was devided to three groups on the location of fracture site and the groups were compared each other. Results: The mean time from injury to checking MRI was 10.7 days. There was no structural abnormality and was no significant difference according to the location of fracture. The patients with history of ankle inversion were 31(88.6%) and the patients with history of chronic or recurrent injury were 22 patients (62.9%). The lesion of MRI related to lateral ankle instability were identified in all patients. Conclusion: This study noted a high incidence of lateral ankle instability that was identified by MRI in the patients of proximal fifth metatarsal fracture. Aggressive treatment for lateral ankle instability should be needed for complications as proximal fifth metatarsal fracture to reduce the recurrence and occurrence.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2001년도 제6차 학술대회 초록집
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• pp.172-172
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• 2001

Purpose： To evaluate compensatory change of opposite hippocampus after temporal lobe surgery in th patient with temporal lobe epilepsy by using single-voxel proton MR spectroscopy. Method： Eighteen patients with intractable temporal lobe epilepsy (TLE) whose MR diagnos was unilateral hippocampal sclerosis (n=11) or localized unilateral anterior temporal lobe lesio (n=7) and who underwent anterior temporal lobectomy were included in the study. Singl proton MRS of opposite hippocampus was carried out on the same day or within 1 week af MR imaging before temporal lobe surgery and after over 1-year post-surgical follow-u Single voxel proton MRS were acquired using GE signa 1.5T scanner and spectrosco system (TR, 1500-2, 000： TE, 136-144). Region of interest (ROI) was placed in a simitar position for all examination to cover the medial temporal lobes including most of the head an body of hippocampus and a part of amygdala, the parahippocampal gyrus. The MR spectr were evaluated with a focus on the metabolite ratio of N-acetylaspartate (NAA choline-containing phospholipids (Cho), creatine (Cr). The metabolite ratios of NAA/ Cr were calculated from the relative peak height measurement. We evaluated change of th intensity ratio NAA/Cr between before and after surgery, to simplify quantification acro patients, because observed decreases in the ratio of NAA/Cr can be interpreted in terms o neuronal or axonal damage.

• Clinical and Experimental Pediatrics
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• 제54권5호
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• pp.212-218
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• 2011

Purpose: The diagnosis of acute pyelonephritis (APN) is often difficult, as its clinical and biological manifestations are non-specific in children. If not treated quickly and adequately, however, APN may cause irreversible renal damage, possibly leading to hypertension and chronic renal failure. We were suspecting the diagnostic value of $^{99m}Tc$-dimercaptosuccinic acid (DMSA) scan by experiences and so compared the results of DMSA scan to those of multi-detector row computed tomography (MDCT). Methods: We retrospectively selected and analyzed 81 patients who were diagnosed as APN by MDCT during evaluation of their acute abdomen in emergency room and then received DMSA scan also for the diagnostic work-up of APN after admission. We evaluated the results of imaging studies and compared the diagnostic value of each method by age groups, <2 years (n=45) and ${\geq}$2 years (n=36). Results: Among total 81 patients with MDCT-proven APN, DMSA scan was diagnostic only in 55 children (68%), while the remaining 26 children (32%) showed false negative normal findings. These 26 patients were predominantly male and most of them, 19 (73.1%) were <2 years of age. Conclusion: DMSA scan holds obvious limitation compared to MDCT in depicting acute inflammatory lesions of kidney in children with APN, especially in early childhood less than 2 years of age. MDCT showed hidden lesions of APN, those were undetectable through DMSA scan in children.