• Title/Summary/Keyword: iSC

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Effects of Inter-Organizational Partner's Relationship Characteristics and IOS Visibility on Supply Chain Performance (파트너 관계특성과 조직간 정보시스템 가시성이 공급망 성과에 미치는 영향)

  • Kim, Moon-Sun
    • The Journal of Society for e-Business Studies
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    • v.18 no.1
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    • pp.13-31
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    • 2013
  • This paper proposes a new concept of inter-organizational systems (IOS) visibility, considering the key role of IOS in IT-enabled supply chain (SC) cooperation. Further, antecedents and consequences IOS visibility have been studied. Antecedents of IOS visibility are identified from the two conflicting theories of inter-organizational relationships, i.e., RDT(resource dependence theory) and RV(relational view). Investigating SC cooperation from the perspectives of both partners (buyers and suppliers) is important, especially when channel partners depend on each other and when asymmetries in IOS visibility can exist. Hence, this study attempts to accommodate both partners' perspectives in IOS visibility and to look into the consequences of IOS visibility from each participant's perspective.

Vasorelaxant Activities of Aqueous Extracts from Twenty Medicinal Plants Used in Oriental Medicines in Isolated Rat Aorta

  • Kim, Eun-Young;Lee, Kyung-Ok;Kim, Dong-Il;Rhyu, Mee-Ra
    • Preventive Nutrition and Food Science
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    • v.15 no.3
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    • pp.189-195
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    • 2010
  • Water extracts from 20 medicinal plants, traditionally used for postmenopausal symptoms in Korea, were examined for their vasorelaxant activity in isolated rat thoracic aorta rings precontracted with norepinephrine (NE). Among the 20 medicinal plants, Cornus officinalis (CoEx, 0.3 mg/mL), Schisandra chinensis (ScEx, 0.3 mg/mL), Erythrina variegate (EvEx, 0.3 mg/mL), and Epimedium koreanum (EkEx, 0.3 mg/mL) showed rapid relaxation of endothelium-intact aorta ($69\pm4%$, $40\pm3%$, $25\pm2%$, and $23\pm3%$ of active tone induced by NE, respectively). In contrast, the extracts of Erythrina variegata (EvEx), Angelica gigas (AgEx), Pueraria thunbergiana (PtEx), and EkEx lead to gradual (i.e., long-term) relaxation to baseline in endothelium-intact vessels. The time to complete relaxation was 20~40 min. These 6 plant extracts were selected for the investigation of possible underlying mechanisms. The CoEx-, ScEx-, or EkEx-induced rapid relaxations were virtually abolished by endothelium denudation, and were significantly inhibited by pretreatment with nitric oxide (NO) synthase inhibitor $N^G$-nitro-L-arginine (L-NNA, 10 ${\mu}M$), indicating that increased formation of NO might contribute to the endothelium-mediated relaxation. In long-term responses, the endothelium denudation did not affect PtEx-induced relaxation, whereas it delayed responses by EvEx and AgEx, and significantly inhibited the effect of EkEx. Among EvEx, AgEx, and PtEx, EvEx attenuated the $CaCl_2$-induced vasoconstriction in high-potassium depolarized medium, implying that EvEx is involved in inhibition of the extracellular calcium influx to smooth muscle through voltage dependent calcium channels. These results provide the scientific rationale for the interrelationships between the use of 20 medicinal plants and their effects on cardiovascular health in estrogen deficient conditions.

Research on Changes in Short Circuit Current of C-Si Solar Cell by Charge Density Waves (전하밀도파 이론으로 결정질 태양전지의 입사각에 따른 단락전류밀도 변화 연구)

  • Seo, Il Won;Koo, Je Huan;Yun, Myoung Soo;Jo, Tae Hoon;Lee, Won Young;Cho, Guang Sup;Kwon, Gi Chung
    • Journal of the Korean Vacuum Society
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    • v.22 no.4
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    • pp.218-224
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    • 2013
  • We measure solar currents transformed from quantum efficiency as a function of incident angles of solar lights. According to conventional models for solar cells, solar currents can be induced when electrons are separated into electrons and holes in the presence of incident solar lights. On the contrary, solar currents can be possible at the time when pinned charge density waves go beyond the pinning potential barrier under the influence of incident solar beams suggested by some authors. In this experiment, measured solar currents and our theory are in good correspondence to confirm the angle dependence of solar lights.

New Transition Metal Mediated Alkylation Reaction of arachno-$S_{2}B_{7}H_{8}$, Insertion Reaction of arachno-$S_{2}B_{7}H_{8}^{-}$ with $(CO)_{5}M$ {${C(R_{1})(R_{2})}$} $(M=Cr,\;W;\;R_{1}=CH_{3},\;C_{6}H_{5};\;R_{2}=OCH_{3},\;SC_{6}H{5})$: Synthesis and Characterization of arachno-$4-RCH_{2}-6,8-S_{2}B_{7}H_{8}\;(R=CH_{3},\;IIa;\;C_{6}H_{5},\;IIb)$

  • Hee-Joo Jeon;Jae-Jung Ko;Kang-bong Lee;Sang Ook Kang
    • Bulletin of the Korean Chemical Society
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    • v.14 no.1
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    • pp.113-117
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    • 1993
  • Good yield synthetic routes for the production of new B-alkyl-dithiaborane clusters are reported. The syntheses of the B-alkyl-dithiaboranes are based on the use of Fischer-type carbene reagents to activate the B-H bonds of dithiaborane for alkyl-addition reactions and are the first examples of transition-mediated reactions of dithiaborane to be reported. Thus, reactions employing arachno-$S_2B_7H_8$- and $(CO)_5M{C(R_1)R_2}$ (M = Cr, W; $R_1 = CH_3,\;C_6H_5;\; R_2 = OCH_3,\;SC_6H_5)$ were found to yield the intermidiate anions I, $[(CO)_5M{C(R_1)R_2S_2B_7H_8}]^-$, which upon protonation gave the corresponding neutral, air-sensitive cluster arachno-4-$RCH_2-6,8-S_2B_7H_8(R=CH_3,\;IIa;\;C_6H_5,\;IIb)$ range from 30 to 35% yield. Complexes IIa and IIb are isoelectronic with arachno-6,8-$S_2B_7H_9$ and, on the basis of the spectroscopic data, are proposed to adopt a similar arachno cage geometry in which an $RCH_2$ units are substituted to 4 position boron atom of the arachno-6,8-$S_2B_7H_9$.

Implementation of FPGA Verification System with Slave FIFO Interface and FX3 USB 3 Bridge Chip (FX3 USB 3 브릿지 칩과 slave FIFO 인터페이스를 사용하는 FPGA 검증 시스템 구현)

  • Choi, Byeong-Yoon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.25 no.2
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    • pp.259-266
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    • 2021
  • USB bus not only works with convenience but also transmits data fast and becomes a standard peripheral interface between FPGA development board and personal computer. In this paper FPGA verification system with slave FIFO interface for Cypress FX3 USB 3 bridge chip was implemented. The designed slave FIFO interface consists of host interface module based on FIFO structure, master bus controller and command decoder and supports streaming communication interface for FX3 bridge chip and memory-mapped input and output interface for user design circuit. The ZestSC3 board with Cypress FX3 USB 3 bridge chip and Xilinx Artix FPGA(XC7A35T-1C5G3241) was used to implement FPGA verification system. It was verified that the FPGA verification system for user design circuit operated correctly under various clock frequencies using GUI software developed by visual C# and C++ DLL. The designed slave FIFO interface for FPGA verification system has modular structure and can be applicable to the different user designs with memory-mapped I/O interface.

Identification of Cell Type-Specific Effects of DNMT3A Mutations on Relapse in Acute Myeloid Leukemia

  • Seo-Gyeong Bae;Hyeoung-Joon Kim;Mi Yeon Kim;Dennis Dong Hwan Kim;So-I Shin;Jae-Sook Ahn;Jihwan Park
    • Molecules and Cells
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    • v.46 no.10
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    • pp.611-626
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    • 2023
  • Acute myeloid leukemia (AML) is a heterogeneous disease caused by distinctive mutations in individual patients; therefore, each patient may display different cell-type compositions. Although most patients with AML achieve complete remission (CR) through intensive chemotherapy, the likelihood of relapse remains high. Several studies have attempted to characterize the genetic and cellular heterogeneity of AML; however, our understanding of the cellular heterogeneity of AML remains limited. In this study, we performed single-cell RNA sequencing (scRNAseq) of bone marrow-derived mononuclear cells obtained from same patients at different AML stages (diagnosis, CR, and relapse). We found that hematopoietic stem cells (HSCs) at diagnosis were abnormal compared to normal HSCs. By improving the detection of the DNMT3A R882 mutation with targeted scRNAseq, we identified that DNMT3A-mutant cells that mainly remained were granulocyte-monocyte progenitors (GMPs) or lymphoid-primed multipotential progenitors (LMPPs) from CR to relapse and that DNMT3A-mutant cells have gene signatures related to AML and leukemic cells. Copy number variation analysis at the single-cell level indicated that the cell type that possesses DNMT3A mutations is an important factor in AML relapse and that GMP and LMPP cells can affect relapse in patients with AML. This study advances our understanding of the role of DNMT3A in AML relapse and our approach can be applied to predict treatment outcomes.

Geochemical Characteristics and Pollution Level of Heavy Metals of Asian Dust in Daejeon Area, 2007 (spring season) (2007년 봄철 대전지역에서 발생한 황사 및 대기부유물의 지구화학적 특성 및 중 금속의 오염도)

  • Lee, Pyeong-Koo;Youm, Seung-Jun;Bae, Beob-Geun
    • Economic and Environmental Geology
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    • v.45 no.3
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    • pp.217-235
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    • 2012
  • We evaluated the geochemical characteristics and their potential pollution of Asian Dusts in Daejeon, Korea during spring 2007. Compared with the chemical compositions of soils in source area of Asian Dust, those of aerosols in Daejeon were enriched with trace elements (ten to hundred fold), inferring that pollutants from China have affected on local environment in adjoining country such as Korea. Chemical analysis of aerosols during Asian dust showed that fine particles ($PM_{2.5}$) contained high contents of trace elements such as Cr, Cu, Pb, Zn, V, S, As, Cd, Co, Ni, Mo, Sb, Cs, Rb, Th, Sc and Y. In the case of TSP (Total Suspended Particle), Zr, Sr, Ba, Li, Th and U were contained much more than other trace elements. The contents of some elements (i.e. Li, Cs, Co, U, Cr, Ni, Rb, V, Th, Y, Sr and Sc) in aerosols collected in Asian Dust period, which are not likely enriched by air pollutants, were higher (2 - 4.2 fold) than those in Non Asian Dust period, indicating that these elements could be used as indicator elements for determining the occurrence of Asian Dust phenomena (especially, Sr, V, Cr & Li). In the case of Asian Dust coming through the big cities and/or industrial areas of China, the domestic aerosols had higher contents of trace elements (such as S, Cd, Zn, Pb, Cu, Mo and As) than those from Northeastern China via North Korea, indicating that the transportation courses of air mass are very important to determine the pollution degrees. Using the enrichment factors of trace elements in aerosols during Asian Dust and Non Asian Dust, we identified that some elements (i.e. S, Zn, Cu, Pb, As, Mo and Cd) were most problematic in terms of environmental hazard aspects, and these elements could affect adverse effects on human health as well as ecosystem and surface environment (soil and water) through long-lived precipitation.

Studies on the Improvement of Utility Value of Corn Grains by Different Processing Methods I. Effects of Different Corn Processing Methods on In situ and In vitro Digestibilities in Hanwoo (옥수수 알곡의 가공처리에 의한 영양소 이용성 향상에 관한 연구 I. 한우에 있어서 옥수수 알곡의 가공처리가 In situ 및 In vitro 소화율에 미치는 영향)

  • Kim, W.Y;Kim, H.W.;Lee, J.H.
    • Journal of Practical Agriculture & Fisheries Research
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    • v.3 no.1
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    • pp.116-131
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    • 2001
  • Experiments were conducted to determine effects of whole and processed corns on in situ disappearance rates of nutrients in the rumen and in vitro degradability of dry matter by rumen microorganisms. Whole corn(WC) was processed into four different types; ground corn(GC), cracked corn(CC), flaked corn(FC), and soaked corn(SC). In the in situ experiment, the rate of ruminal DM disappearance after 48 hour incubation was highest in GC(76.1%) and lowest in WC and SC(12% ; P<0.01). The rate of ruminal CP disappearance after 48 hour incubation was highest in GC and CC(48 and 38%, respectively; P<0.01). The rate of ruminal OM disappearance after 48 hour incubation was highest in GC(76.14%) and lowest in WC and SC(11.82 and 12.26%, respectively; P<0.01). In the in vitro experiment, the two-stage incubation technique was used to measure digestibilities of whole and processed corns. The digestibility of DM was higher in GC, CC and FC(86.95, 85.84 and 82.29%, respectively) than in WC(15.36%; P<0.01).

Spectroscopic Survey of G and K Type Dwarfs in the Hipparcos Catalog

  • Kim, Bokyoung;An, Deokkeun;Lee, Young Sun;Stauffer, John R.;Terndrup, Donald M.;Johnson, Jennifer
    • The Bulletin of The Korean Astronomical Society
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    • v.40 no.1
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    • pp.70.5-71
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    • 2015
  • We present a preliminary result from a high-resolution and high signal-to-noise spectroscopic survey, providing atmospheric parameters for about 170 nearby field dwarfs in the Hipparcos catalog. Our preliminary analysis shows that when Hipparcos parallaxes are adopted, a few stars in our sample are too faint compared to main-sequence fitting distances based on our accurately measured [Fe/H]. We discuss magnitude deficits of these field stars in connection with the short Hipparcos distance to the Pleiades.

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박형웨이퍼를 사용한 결정질 태양전지의 PC1D를 이용한 최적화

  • Im, Tae-Gyu;Jeong, U-Won;Lee, Jun-Sin
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2009.11a
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    • pp.38-38
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    • 2009
  • Wafer thickness of crystalline silicon is an important factor which decides a price of solar cell. PC1D was used to fix a condition that is required to get a high efficiency in a crystalline silicon solar cell using thin wafer($150{\mu}m$). In this simulation, base resistivity and emitter doping concentration were used as variables. As a result of the simulation, $V_{oc}$=0.6338(V), $I_{sc}$=5.565(A), $P_{max}$=2.674(W), FF=0.76 and efficiency 17.516(%) were obtained when emitter doping concentration is $5{\times}10^{20}cm^{-3}$, depth factor is 0.04 and sheet resistance is $79.76{\Omega}/square$.

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