• Journal of Chest Surgery
• /
• 제16권2호
• /
• pp.255-259
• /
• 1983

Thirteen cases of traumatic diaphragmatic injuries treated at the Dept. of Thoracic & Cardiovascular Surgery in Kyung-Hee University Hospital from Jan. 1973 to Dec. 1982, were reviewed in this study. 1. Of 13 cues, 11 were male and 2 were female, a ratio of 5.5:1. This ratio revealed high incidence in male patients. The age distribution was ranged from 2 to 59 years. 2. The causes of traumatic diaphragmatic injuries; 6 were traffic accidents, 4 were stab wounds, 1 was falling down, 1 was gun shot wound and 1 was kick. 3. Operation were performed in 11 patients. No operation was done in 2 patients. 4. There were 100% of other associated injuries, the most frequent was having hemothorax. 5. 2 cases of death occurred in not operated patients. One was intracranial hematoma, and the other was hypertensive encephalopathy.

• 대한한방내과학회지
• /
• 제33권4호
• /
• pp.543-557
• /
• 2012

Objectives : The purpose of this study which adopted a qualitative method was to evaluate blood pressure management behaviors of pre- and stage 1 hypertension patients and to provide fundamental data for developing a strategy about proper oriental medical treatment through analyzing factors related to a moxibustion clinical trial. Methods : Semi-structured interviews that focused on personal experiences with hypertension and its management were conducted with 10 hypertensive patients. The interviews lasted for approximately 50 minutes. Results : Most participants recognized that the direct cause of high blood pressure was unhealthy behavior rather than inheritance. Thus, the hypertensive patient believed they could recover their blood pressure to a normal level through removing the direct cause of hypertension instead of taking drugs. The reasons for these statements were that the drugs for controlling hypertension are not natural and they may have side effects. On future management plan of patients, most of them will continue to keep moxibustion and healthy behavior in the well-controlled blood pressure group. However in the uncontrolled blood pressure group, there was an increasing tendency to begin medication. Conclusions : For developing a strategy for an individual approach to hypertension management, we need to develop a client-centered attitude and strategy. That is, we need to tailor our approach to individual cases to avoid generalizations and stereotyping when developing an adherence increasing strategy.

• 한국콘텐츠학회논문지
• /
• 제20권9호
• /
• pp.503-510
• /
• 2020

본 연구는 금연을 통한 혈압조절이 중요한 고혈압 환자군과 정상 혈압군을 대상으로 각각의 금연의사와 관련된 요인을 파악하고 비교하기 위한 이차자료 분석 연구이다. 2010년부터 2018년까지 1,981명(고혈압 환자군 407명, 정상 혈압군 1,574명)을 대상으로 분석하였다. 교차분석에서 유의한 변수에 대한 다변량 로지스틱 회귀분석을 실시한 결과 고혈압 환자에서의 유의한 변수는 결혼상태, 교육수준, 주관적 건강상태, 최근 1주일간 한번에 적어도 10분 이상 걸은 날수이었으며, 정상 혈압군에서는 흡연량으로 두 군에서 차이를 보였다. 흡연자의 고혈압 여부 등 대상자의 특성에 따른 맞춤형 관리와 금연교육을 통해 효과를 높일 필요가 있으며, 심뇌혈관질환 등 이차적 질환으로의 발생이 가능한 고혈압 환자군 우선의 집중 교육을 통해 금연의사를 높여야 할 것이다.

• 성인간호학회지
• /
• 제12권4호
• /
• pp.533-545
• /
• 2000

The purpose of this study was to identify the effect of social support revealed in the time duration of sick role behavior compliance on the patients with hypertension using Quasiexperimental research design. Data collection was made through the interview survey technique from the hypertensive patients who received social support intervention (experimental group, n=41) and from those who were not exposed to the intervention(control group, n= 34). The subjects were registered in the cardiovascular outpatient clinic at the Chonnam National University Hospital from June 3, 1996 to November 30, 1997. $\chi^2$-test or t- test, Repeated measures ANOVA were utilized in the data analysis. The results were as follows: 1. The effect of social support intervention on sick role behavior compliance was significant in 1 month(F=69.17, p=.000), 6 months (F=11.51, p=.001), and 12 months(F=.07, p=.789) and between two groups(1 month; F=153.70, p=.000, 6 months; F=13.94, p=.000, 12 months; F=6.72, p= .011). 2. The effect of social support intervention on blood pressure was not significant through all the periods of time (F=1.21, p=.274) between the two groups(F=.12, p=.732). In conclusion, it was showed that social support had an effect on sick role behavior compliance and the effect of social support continued for twelve months(F= 10.03, p=.002) However, the score of compliance tends to decrease after 6 months of intervention. Therefore, this study indicated that social support re-intervention would be needed between six and twelve months.

• 대한한방내과학회지
• /
• 제42권5호
• /
• pp.808-819
• /
• 2021

Objectives: This study considered the effectiveness of integrative Korean medical treatment for stress-induced hypertensive patients without the use of conventional medication. Methods: A 62-year-old female with stress-induced hypertension (HTN) was hospitalized for 33 days. Her pattern identification was ascendant hyperactivity of liver yang (Ganyangsanghang)-type HTN. Herbal medicine and acupuncture were used for the treatment: Cheonggansoyo-san for 33 days and Chunwangbosim-dan for 15 days, together with acupuncture for 20 minutes twice a day. Blood pressure was checked daily during hospitalization with a digital sphygmomanometer in the brachial artery. Results: After 33 days of treatment, blood pressure decreased. The Handicap Inventory (DHI) scale and Pittsburg Sleep Quality Index (PSQI) scores both decreased. The patient also reported fewer complaints. A five-month follow-up after discharge, with no further treatment, confirmed stable blood pressure. Symptom improvements continued with no significant side effects. Conclusions: This study indicates that Korean medical treatment is effective for stress-induced hypertensive patients.

• Clinical and Experimental Pediatrics
• /
• 제52권2호
• /
• pp.187-193
• /
• 2009

목 적 : Adiponectin은 대사 증후군에서 중요한 역할을 하는 물질이며, 비만, 2형 당뇨, 관동맥 질환 등에서 그 수치가 감소하는 것으로 알려져 있다. 고혈압과 혈청 adiponectin치의 관계는 여러 저자에 의하여 발표되었으나 아직 논란의 여지가 남아있는 상태이다. 우리는 낮은 adiponectin치가 청소년 고혈압과 어떤 관계가 있는지, 또 영향을 끼치는 기전이 유전적인지 혹은 생물학적인 것인지 알고자 유전자 다형성 분석을 하였다. 방 법 : 16에서 17세 사이의 40명의 고혈압 청소년과 20명의 대조군 청소년을 대상으로 각 군의 혈청 adiponectin, insulin, renin, aldosterone, ACE를 측정하여 비교하였다. cIMT와 PWV도 측정하였다. PCR법으로 adiponectin I164T 유전자 다형성을 조사하였다. 결 과 : 고혈압 청소년군에서 cIMT와 PWV가 의미있게 높았다. 혈청 insulin, renin, aldosterone치도 고혈압군에서 의미있게 높았다. 두 군간에 adiponectin치는 의미있는 차이를 보이지 않았다. 본 연구에 참여한 청소년에서는 TC genotype은 발견되지 않았고 모두 TT genotype을 보였다. 결 론 : 결론적으로 adiponectin치는 고혈압 청소년 군에서나 정상군에서나 차이가 없었다. 두 군에서 유전적인 다형성도 보이지 않았다. 더 큰 규모의 연구가 필요할 것으로 생각된다.

• Nutrition Research and Practice
• /
• 제11권3호
• /
• pp.214-222
• /
• 2017

BACKGROUND/OBJECTIVES: Glutathione S-transferase (GST) forms a multigene family of phase II detoxification enzymes which are involved in the detoxification of xenobiotics by conjugating substances with glutathione. The aim of this study is to assess the antioxidative status and the degree of DNA damage in the subclinical hypertensive patients in Korea using glutathione S-transferase polymorphisms. SUBJECTS/METHODS: We examined whether DNA damage and antioxidative status show a difference between GSTM1 or GSTT1 genotype in 227 newly diagnosed, untreated (systolic blood pressure $(BP){\geq}130mmHg$ or diastolic $BP{\geq}85mmHg$) subclinical hypertensive patients and 130 normotensive subjects (systolic BP < 120 mmHg and diastolic BP < 80 mmHg). From the blood of the subjects, the degree of the DNA damage in lymphocyte, the activities of erythrocyte superoxide dismutase, the catalase, and the glutathione peroxidase, the level of glutathione, plasma total radical-trapping antioxidant potential (TRAP), anti-oxidative vitamins, as well as plasma lipid profiles and conjugated diene (CD) were analyzed. RESULTS: Of the 227 subjects studied, 68.3% were GSTM1 null genotype and 66.5% were GSTT1 null genotype. GSTM1 null genotype had an increased risk of hypertension (OR: 2.104, CI: 1.38-3.35), but no significant association in GSTT1 null genotype (OR 0.982, CI: 0.62-1.55). No difference in erythrocyte activities of superoxide dismutase, catalase, or glutathione peroxidase, and plasma TRAP, CD, lipid profiles, and GSH levels were observed between GSTM1 or GSTT1 genotype. Plasma levels of ${\alpha}-tocopherol$ increased significantly in GSTT1 wild genotype (P < 0.05); however, plasma level of ${\beta}-carotene$ increased significantly in GSTT1 null genotype (P < 0.01). DNA damage assessed by the Comet assay was significantly higher in GSTM1 null genotype than wild genotype (P < 0.05). CONCLUSIONS: These results confirm the association between GSTM1 null genotype and risk of hypertension as they suggest that GSTM1 null genotype leads to an increased oxidative stress compared with wild genotype.

• 한국의료질향상학회지
• /
• 제2권1호
• /
• pp.68-84
• /
• 1995

Background: Guideline for practice is useful because it can be the standard for assessment and way to improve quality. We need to take account of expert opinion and consensus as well as scientific evidences to develope practice guideline because it should be practical. Delphi method has been developed to gather opinions from experts fairly. This study was designed to develop practice guideline and apply it to practices as a method to improve quality in primary medical care. Methods: Hypertension(in adults over 18 years old) was selected as a target problem. Self questionnaires about management of hypertensive patients were developed by a researcher with advice of 11 experts. The questionnaires were designed to response as a 5 pont scale. The results of previous questionary were given to respondents in second and third questionnaires. If needed, the questionnaires were changed on the previous responses. The items with medium greater than or equal to 4 point in 1st and 2nd responses were accepted in guideline. The items with medium lesser than or equal to 3 point were questioned again about whether they can be excluded or not. The criteria for assessment was made with reference to guideline and applied to 85 hypertensive patients of 9 family practitioners. At 3 months after practice guideline had been given to family practitioners, performance of same practitioners was assessed with 36 new hypertensive patients. Results: 23 professors in family medicine, 22 family practitioners and 6 cardiologists, responded among 50, 50, 15 respectively. Practice guideline with 33 items was developed as a result of 3 times questionaires. The difference of responses between professors in family medicine, family practitioners and cardiologists was not significant. Performance of practice was improved in diagnosis, history taking about 6 fields, laboratory examination and decision making about time of pharmaceutical prescription. It was not improved in physical examination, life style modification, method of pharmaceutical prescription, choice of initial antihypertensives and history taking about duration of disease and diet habit. It was decreased in history taking about psychosocial factors. The assessment scores were low in history taking, physical examination and life style modification before and after use of practice guideline. Conclusion: Practice guideline for hypertension could be developed by Delphi method. Performance of practice improved partially after use of guideline.

• 한국산학기술학회논문지
• /
• 제16권10호
• /
• pp.7078-7088
• /
• 2015

본 연구의 목적은 노인 고혈압 환자의 건강행태, 수면 관련 요인이 인지기능에 미치는 영향을 파악하는 것이다. 연구대상은 지역사회에 거주하는 65세 이상 노인 중 고혈압을 진단 받은 140명이었다. 자료 수집은 2013년 2월 5일부터 5월 1일까지로 일대일면접 설문조사로 시행되었다. 연구도구는 Pittsburgh Sleep Quality Index(PSQI), Epworth Sleepiness Scale(ESS)와 한국어판 노인용 간이정신상태 검사 도구를 사용하여 측정하였다. 연구결과, 노인고혈압 환자의 인지기능은 수면의 질 저하와 유의한 음의 상관관계를 나타냈다(r=-.29, p<.001). 수면시간은 체질량지수(r=-.18, p=.032) 및 수면의 질 저하(r=-.59, p<.001)와 유의한 음의 상관관계가 있었고, 주간졸음과는 유의한 양의 상관관계가 있었다(r=.22, p=.008). 위계적 회귀분석 결과, 노인 고혈압 환자의 연령, 교육수준, 거주유형은 인지기능과 유의한 관련성이 있으며(F=8.56, p<.001, Adjusted $R^2=.14$), 인구사회학적 특성과 건강행태를 통제한 상태에서 수면의 질 저하(${\beta}=-.27$, p=.008)는 인지기능에 유의한 영향을 미치며, 최종 모형의 설명력은 17%였다(F=4.09, p<.001). 그러므로 노인 고혈압 환자의 인지기능 향상전략은 연령, 교육수준, 거주유형을 고려하고, 낮은 수면의 질을 향상 시킬 수 있는 치료적인 중재가 도움이 될 것으로 사료된다.

• 사상체질의학회지
• /
• 제19권2호
• /
• pp.127-142
• /
• 2007

1. Objectives We studied the characteristics of pulse wave variables in hypertensive patients and healthy subjects and would develope the program diagnosing Sasang Constitution. 2. Methods Healthy subjects and hypertensive patients were measured with pulse analyzer. In each of healthy and hypertensive group, means of pulse analyzer variables were compared among Constitution. On these bases of these results, decision tree composed of several rules were developed. 3. Results and Conclusions Decision tree with 72.13% accuracy were developed. (1) if h5(Cheok) < 2.325 & Wm/t(Cheok) < 0.238281 then class = Soeumin (2) if h5(Cheok) < 2.325 & Wm/t(Cheok) ${\ge}$ 0.238281 then class = Taeumin (3) if h5(Cheok) ${\ge}$ 2.325 & t1(Chon) ${\ge}$ 0.143 then class = Soyangin (4) if h5(Cheok) ${\ge}$ 2.325 & t1(Chon) < 0.143 & h3/h1(Cheok) ${\ge}$ 0.963601 then class = Soyangin (5) if h5(Cheok) ${\ge}$ 2.325 & t1(Chon) < 0.143 & h3/h1(Cheok) < 0.963601 & sum of pulse pressure(SPP) of Gwan ${\ge}$ 618 then class = Taeumin (6) if h5(Cheok) ${\ge}$ 2.325 & t1(Chon) < 0.143 & h3/h1(Cheok) < 0.963601 & sum of pulse pressure(SPP) of Gwan < 618 & t3(Chon) < 0.209 then class = Soeumin (7) if h5(Cheok) ${\ge}$ 2.325 & t1(Chon) < 0.143 & h3/h1(Cheok) < 0.936601 & sum of pulse pressure(SPP) of Gwan < 618 & t3(Chon) ${\ge}$ then class = Taeumin From above results, we concluded that pulse analyzer is useful instrument to decide Sasang Constitution.