• Title/Summary/Keyword: hydrocarbone

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The penetration site of local anesthetics into liposomal membrane

  • Han, Suk-Kyu;Bae, Song-Ja;Il-Yun;Kim, Nam-Hong
    • Archives of Pharmacal Research
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    • v.8 no.4
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    • pp.205-211
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    • 1985
  • The distribution of local anesthetics between the hydrocarbone interior and surface area of the lipid bilayer of liposomal membrane was calculated employeg fluorescence probe technique. The quenching of fluorescence probe technique. The quenching of fluorescence probe technique. The quenching of fluorescence of 12-(9-anthroyl) stearic acid and N-octadecyl naphthyl-2-amini-6-sulfonic acid by the local anesthetics in liposomal system was used to calculate the distribution. The Stern-Volmer equation was modified and employed for this calculation. The results showed that procaine hydrocloride and benzocaine were mainly distributed on the surface area of the lipid bilayer of the liposoal membrane, while tetracaine hydrochloride penetrated effectively into the hydrocarbon interior and showed even distribution in the lipid bilayer.

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A CASE REPORT OF HALOTHANE INDUCED TOXIC HEPATITIS (HALOTHANT 전신마취후 발생한 독성간염)

  • Paik, Un-Bong;Yoon, Kyu-Ho;Rho, Young-Seo;Park, Sung-Won;Shin, Myoung-Sang;Heo, Nam-Oh
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.16 no.3
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    • pp.315-320
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    • 1994
  • General anesthesia is necessary to operation in dept. of oral and maxillofacial surgery. Halothane is one of the most commonly used anesthetic agent for general anesthesia because of its property of nonexplosive, inexpensive, strong activeness and chemical stability. Halothane is fluorinated hydrocarbone anesthetic agent and structurally similiar to chloroform. On the contrary halothane has been reported to result in severe hepaitc necrosis in a small number of individuals. Although the mechanism of halothane induced toxic hapatitis is unclear, it appears to be closely related to reducting metabolite, reactant intermediate product, immune reaction, hypersensitivity and so on. This is a case report of 27 years old male patient occured halothane induced hepatitis following after operation of mandible fracture.

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Adhesion Properties of Low VOC-type Primer Containing Acrylic Modified Tackifier Resin (Acrylic Modified Hydrocarbone Resin을 포함하는 저독성 프라이머의 제조 및 특성)

  • Jeong, Boo-Young;Cheon, Jung-Mi;Oh, Sang-Taek;Chun, Jea-Hwan;Jo, Nam-Ju
    • Journal of Adhesion and Interface
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    • v.12 no.1
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    • pp.11-15
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    • 2011
  • In this study we synthesized low VOC-solvent soluble thermo plastic polyurethane, The effect of chain extender and NCO/OH ratio for properties of thermoplastic polyurethane was investigated. Also, we prepared low VOC-type primer by TPU and acrylic modified tackifier resin. When NCO/OH ratio was 2 or more, TPU was insoluble in low VOC solvent. And peel strength was higher value using polar type tackifier than non-ploar type tackifier.

Changes on the Flavor Components in the Leaf Teas of Lindera obtusiloba BL. by Processing Methods (제조방법에 따른 생강나무(Lindera obtusiloba BL.) 잎차의 향기 성분의 변화)

  • Hwang Kyung-A;Shin Seung-Ryeul;Kim Kwang-Soo
    • Food Science and Preservation
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    • v.12 no.1
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    • pp.68-74
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    • 2005
  • This study was carried out to analyze to the flavor components of Lindera obtusiloba BL leaf teas by different processing methods. 81 kinds of flavor components in the masted tea, 78 in the roasted tea after steaming, 88 in the withered tea, 86 in the fermented tea, 72 in the steamed tea, and 89 in the air dried tea ware by GC/MS. Hydrocarbones in Lindera obtusiloba BL leaf teas were 45 kinds of $\beta-piepne$, and 16 kinds of alcohols such as Linalool, n-octanoal, phenyl acetaldehyde, $(-)-\alpha-terpineol$, elemol, and cholest-5-en-3-ol. 11 kinds of ketones sachas 2-ethyl-2- propyl-cyclohexanone, and 8 kinds of aldehydes sach as phenyl acetaldehyde, tetradecanal, 10-undecanal, 4-Bromo-2-methylbutanal were found. Esters were methyl 9,12,15-octadecatrienate, didodecyl phthalace, 1,2-benzenediccarbaboxy acid-bis (2-ethylhexyl)ester and phenols was 2,6-bis(1,1-dimethylethyl)-4-methyl-phenol.

Material Characteristics and Clay Source Interpretation of the Ancient Ceramic Artifacts from the Wonsinheungdong Site in Daejeon, Korea (대전 원신흥동 유적 출토 고대 세라믹 유물의 재료학적 특성과 원료의 산지해석)

  • Kim, Ran-Hee;Jung, Hae-Sun;Jung, Sang-Hoon;Lee, Chan-Hee
    • Journal of Conservation Science
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    • v.27 no.2
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    • pp.163-179
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    • 2011
  • This study was to identify the material characteristics and provenance of the crucibles, potteries and roof tiles from the Wonsinheungdong site in Daejeon, Korea. Similar mineral composition of each samples showed by microscopic observation and X-ray diffraction analysis. However, wall thickness and mineral characterization of each ceramic artifacts are quite different. The pottery is characterized by thin wall with 0.5 to 0.7 cm and fine grained clay matrix. While the crucible and roof tile has thick wall with 1.3 to 2.5 cm, poorly sorted texture of many quarz, orthoclase and plagioclase whithin ceramic fabric. And large elonagated voids formed by hydrocarbone of straw during the firing and loose matrix obseved in crucible. All ceramic samples and ground soil of the site show similar mineralogical characteristics geochemical behavior and clay-mineralization degree. This indicates making that the soil is probable to be a raw material of all ceramic from the Wonsinheungdong site. Also, firing temperature of most ceramic artifacts are estimated as 850 of all ceramic from the Wonsinheungdong site. Also, firing temperature of most ceramic artifacts are estimated as 850 to $950^{\circ}C$ but hardest pottery fired high temperature between 1,050 to $1,150^{\circ}C$. The vitreous molten materials interpreted in slag included segregation of copper and tin. But it can not exclude the possibility that the glass molten material because observed reddish and greenish vitreous fine structure under microscopic.

Functional and Volatile Flavor Compounds in Traditional Kyungsando Squid sikhe (경상도 전통마른오징어 식해의 향기성분 및 기능성)

  • Choi, Cheong;Lee, Hee-Duck;Choi, Hee-Jin;Son, Jun-Ho;Kim, Sung;Son, Gyu-Mok;Cha, Woen-Suep
    • Korean Journal of Food Science and Technology
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    • v.33 no.3
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    • pp.345-352
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    • 2001
  • The volatile compounds of traditional Kyungsando squid sikhe were identified by GC-MS. The amount of ${\alpha}-zingibirene$ among identified volatile compounds was 19.73 mg/kg. The major volatile compounds of sikhe were (Z)-Di-2-propenyl disulfide, ${\alpha}-curcumene$, methyl allyl disulfide, (E, E)-a-farnesene, pentanol, z-citral, 3-ethyl-1,2-dithi-5-ene-${\beta}-elemene$, ${\beta}-elemene$, acetic acid, and ${\beta}-phellandrene$. The volatile compounds of sikhe were compose of 49 including hydrocarbone groups, 15 aldehydes groups, 33 alcohol groups kinds, 11 ketone and ester groups. The fraction obtained from sikhe were tested for electron donating ability, angiotensin converting enzyme inhibitory activity and xanthine oxidase inhibitory activity. There were no electron donating abilities$(SC_{50})$ in hexane and water soluble fractions. On the other hand, the angiotensin converting enzyme abilities of ethylacetate and butanol soluble fractions were $310.64\;{\mu}g/mL$ and $1096.49\;{\mu}g/mL$, respectively. Angiotensin converting enzyme inhibitory activities$(IC_{50})$ of ethylacetate butanol soluble fractions were 1.623 mg/mL and 1.303 mg/mL, respectively. Xanthine oxidase inhibitory activities$(IC_{50})$ of ethylacetate fraction and butanol soluble fractions were 3.591 mg/mL and 2.083 mg/mL, respectively.

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