Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
권호 표지

A CASE REPORT OF HALOTHANE INDUCED TOXIC HEPATITIS

HALOTHANT 전신마취후 발생한 독성간염

  • Paik, Un-Bong (Department of oral and maxillofacial surgery, Sanggae paik Hospital College of Medicine, Inje University) ;
  • Yoon, Kyu-Ho (Department of oral and maxillofacial surgery, Sanggae paik Hospital College of Medicine, Inje University) ;
  • Rho, Young-Seo (Department of oral and maxillofacial surgery, Sanggae paik Hospital College of Medicine, Inje University) ;
  • Park, Sung-Won (Department of oral and maxillofacial surgery, Sanggae paik Hospital College of Medicine, Inje University) ;
  • Shin, Myoung-Sang (Department of oral and maxillofacial surgery, Sanggae paik Hospital College of Medicine, Inje University) ;
  • Heo, Nam-Oh (Department of oral and maxillofacial surgery, Sanggae paik Hospital College of Medicine, Inje University)
  • 백운봉 (인제대학교 의과대학 부속 상계백병원 악안면구강외과학교실) ;
  • 윤규호 (인제대학교 의과대학 부속 상계백병원 악안면구강외과학교실) ;
  • 노영서 (인제대학교 의과대학 부속 상계백병원 악안면구강외과학교실) ;
  • 박성원 (인제대학교 의과대학 부속 상계백병원 악안면구강외과학교실) ;
  • 신명상 (인제대학교 의과대학 부속 상계백병원 악안면구강외과학교실) ;
  • 허남오 (인제대학교 의과대학 부속 상계백병원 악안면구강외과학교실)
  • Published : 1994.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

General anesthesia is necessary to operation in dept. of oral and maxillofacial surgery. Halothane is one of the most commonly used anesthetic agent for general anesthesia because of its property of nonexplosive, inexpensive, strong activeness and chemical stability. Halothane is fluorinated hydrocarbone anesthetic agent and structurally similiar to chloroform. On the contrary halothane has been reported to result in severe hepaitc necrosis in a small number of individuals. Although the mechanism of halothane induced toxic hapatitis is unclear, it appears to be closely related to reducting metabolite, reactant intermediate product, immune reaction, hypersensitivity and so on. This is a case report of 27 years old male patient occured halothane induced hepatitis following after operation of mandible fracture.

Keywords