• Fire Science and Engineering
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• v.30 no.1
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• pp.81-85
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• 2016

Reasonable disaster prevention signs play an important role in guiding evacuation. Through the field investigation on disaster prevention signs in shelters and surrounding areas in Beijing, some problems were found in the using of sign system. Based on the principle of integrated design, evacuation and rescue requirements, it is necesssary to make further study on aspects such as, design of function, systematic consideration, humanization design, as well as the internationalization using. This paper presents an evaluation index system for disaster prevention signs. Such a system is very important for strengthening the independent guiding function of sign systems and improving evacuation efficiency. An effective connection could be realized between the internal environment of buildings, evacuation routes, and emergencey shelters.

• Philosophy of Education
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• no.49
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• pp.235-270
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• 2013

The aim of this study is to make clear the significance of art education for solving problem in elementary and secondary school. These days, our students have so many negative problems in school and society, for example, school violence, group teasing, group outcasts, arrogate teacher's authority, school collapse, dehumanization get soused excessive and such like. We must support to make humanization through a normal art education and art class. Art, music, physical and literature education is a good methods for human education and mental therapy. The best art education is enlightening the children's imagination and curiosity. To enlighten. in art class at the school, teachers must think about enlightening the children's imagination and curiosity. Aesthetic experience includes creative activities and appreciative activities for human formation. The school must expend effort to increase the art class in each week, because students can change positively in aesthetic experience and aesthetic environment.

• Journal of Families and Better Life
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• v.2 no.1
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• pp.93-109
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• 1984

The purpose of this study is to investigate the direction and strategy of education for sex role concepts of children on the basis of factor analysis of the present situation in sex role concepts and their formation. Although some maintain that sex role concept of our society has been changing slowly, the traditional sex role concept still dominates and is potentially immanent. the analysis of present condition of our society indicates that the formal as well as informal education are facing with various crucial problems in providing the direction of behavior demanded for carrying out the role. The close analysis of the three theories, psychoanalytic theory , social learning theory, cognitive development theory, lends a support to the laim of the study that cognitive development theory provide an integrated frame of reference for us to see the sex role education analytically Furthermore, the factors which are found to have influences on the formation of sex role have been analyzed in three areas: Family, School and society. 1)The factors in family such as parental behavior of upbringing and their concepts of sex role have a direct relationship with the nature of sex tole concept of children. Therefore, the first step to make children to habe a new type of sex-role conception appropriate for modern societies is to change that of parental conception and attitudes. 2)the quantitative as well as the qualitative aspects of school education showed no exceptional trend from the dominant conception of the society, although school are expected to lead the society as formal education institution rather than just reflect the society. The educational activities and contents such as the conceived goal of education for eoch sex, textbook constitation, teaching behavior and sex-role concepts of teacher are found to be still dominated by the traditional sex-role assumption. 3) The social factors that have direct relationship with children's sex-role formation are social and cultural, which include social milieu, condition of employment, family structure and mass-media. Since family and school do not educate the young in a social vacuum. their educational function of sex-role formation are doomed to be limited and determined by these social factors. Unfortunately, the analysis of present conditions showed the dominance of traditional types of sex-role concepts in all these social factors. The education of sex-role concept for children should be treated as one of the most crucial value problems related with many other important problems, such as direction and patterns of behaviors of each sex, the degree of self-development and capabilities, and consequently human right, equality, humanization and the quality of happiness. Neverthless, the analysis of researches on sex-role education which have been surveyed in this study lead to a conclusion that concerted effort to change the education, formal as well as informal should be provided in every aspect of social life. If the sex role education of the past has aimed at the "feminization"of girls which indoctrinate girls into a limited and fixed role of house wives, the new education in the future should be directed foward "humanization" of both sexes which opens the diversity of roles for both boys and girl on equal levels and provide future possibilities in accordance to their individual capabilities and interests.

• Journal of Korean Philosophical Society
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• no.126
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• pp.85-115
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• 2019

With the dramatic development of science and technology since the twentieth century, attempts to overcome human's natural and physical limitations through technology have actually reached a peak. Transhumanism is a movement that strongly affirms these human technological attempts. However, this optimistic belief of transhumanism in technology meets the strong resistance of opponents contending that transhumanism might destroy human nature and severely undermine human values and rights. The focus of the transhumanism debate lies in what technology means to humans. However, in order to exactly grasp the essence of transhumanism, we should first consider our 'life-world', where technology and humans are closely intertwined. The word 'life-world(Lebenswelt)' which originally comes from Husserl, is an open and universal world as a horizon that is the basis of all human practical activities and at the same time encompasses its products in itself. According to Husserl, the process of incorporating human products into the life-world is a kind of 'familiarization' process through which specific theories and techniques are harmonized with our lives in the life-world. Such harmonization and familiarization of technology could be also considered a humanization of technology. It is a process in which technology is assimilated and corresponds to the finiteness of human and the life-world. In this sense, we could say that the transhumanistic attempts are just a natural expression of human desire to be perfect in the life-world and that they should not be overly concerned or overestimated.

• Journal of Microbiology
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• v.45 no.6
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• pp.572-577
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• 2007

To enhance therapeutic potential of murine monoclonal antibody, humanization by CDR grafting is usually used to reduce immunogenic mouse residues. Most humanized antibodies still have mouse residues critical for antigen binding, but the mouse residues may evoke immune responses in humans. Previously, we constructed a new humanized version (AKA) of mouse CC49 antibody specific for tumor-associated glycoprotein, TAG-72. In this study, to select a completely human antibody light chain against TAG-72, guided selection strategy using phage display was used. The heavy chain variable region (VH) of AKA was used to guide the selection of a human TAG-72-specific light chain variable region (VL) from a human VL repertoire constructed from human PBL. Most of the selected VLs were identified to be originated from the members of the human germline VK1 family, whereas the VL of AKA is more homologous to the VK4 family. Competition binding assay of the selected Fabs with mouse CC49 suggested that the epitopes of the Fabs overlap with that of CC49. In addition, they showed better antigen-binding affinity compared to parental AKA. The selected human VLs may be used to guide the selection of human VHs to get completely human anti-TAG72 antibody.

• The Journal of the Korea Contents Association
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• v.15 no.8
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• pp.85-95
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• 2015

This study examined adaptational aspects by analyzing culture contents, which use Jeju myth "Chasabonpuri" as a writing material. "Chasabonpuri" has a heroic narration of Ganglim, who becomes the grim reaper by solving the serious problem through a journey to the world beyond. Also, it has a value as an archetypal narration because of its reflection on Korean world view of afterlife. Culture contents, which use "Chasabonpuri" as a writing material, have features of 'accurate reproduction of heroic narration' (Ganglim who becomes the grim reaper), 'tragic conversion of narration through humanization' (The way home), 'extension of narration through merging with traditional and modern elements'(Together with God), 'Unique view of the world that reflects the contemporary trend' (Ghost Messenger).

• Korean Journal of Psychosomatic Medicine
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• v.1 no.1
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• pp.14-24
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• 1993

The author discussed present problems and future prospects of psychosomatic medicine in clinical, educational, research, and social aspects. In general, psychosomatic field. particularly. consultation-liaison(C-L) psychiatry in Korea seems to remain on early developmental phase. However, positive change in the general publics' and societal view of psychiatry, specialization of medicine and development of medical technology, implementation of delivery system in medical care could contribute to development of this field. In future, clinically, liaison activity will be more activated. and this field will be developed as main subspecialty of psychiatry. In addition. C-L psychiatry will be subspecialized. and prevention and humanization of medical care could be more emphasized. In education. the main place of education for medical students and psychiatric residents will be changed from closed ward to general ward in which consultation-liaison activity can be performed. In research. consultation liaison model suitable for Koreans will be developed and studies on disease mechanism will be more promoted. In social aspects, this field could influence the general publics' view of psychiatry and change the whole areas of medicine and society toward integration. In order to achieve these goals, medical insurance system and cost relevant to C-L activity should be essentially improved.

• Journal of Plant Biotechnology
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• v.36 no.4
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• pp.309-319
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• 2009

Transgenic plant cell cultures for the production of biopharmaceuticals including monoclonal antibodies, recombinant proteins have been regarded as an alternative platform in addition to traditional microbial fermentation and mammalian cell cultures. Plant-made pharmaceuticals (PMPs) have several advantages such as safety, cost-effectiveness, scalability and possibility of complex post-translational modifications. Increasing demand for the quantity and diversity of pharmaceutical proteins may accelerate the industrialization of PMP technology. Up to date, there is no plant-made recombinant protein approved by USFDA (Food and Drug Administration) for human therapeutic uses due to the technological bottlenecks of low expression level and slight differences in glycosylation. Regarding expression levels, it is possible to improve the productivity by using stronger promoter and optimizing culture processes. In terms of glycosylation, humanization has been attempted in many ways to reduce immune responses and to enhance the efficacy as well as stability. In this review article, all these respects of transgenic plant cell cultures were summarized. In addition, we also discuss the general characteristics of plant cell suspension cultures related with bioreactor design and operation to achieve high productivity in large scale which could be a key to successful commercialization of PMPs.

• Korean Institute of Interior Design Journal
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• v.15 no.1 s.54
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• pp.3-11
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• 2006

After the 60's, The discourse of the Art of Reception, semiotics, and epistemology have been made steady progress. Especially, the Art of Reception which emphasizes the role of reader in the process of understanding the text, had made the significant role of the Border Dismantling in the Architecture. Its concept can be difined as the free interpretation of each individuals on the art works, that abhors the one-directional systems between reader and writer. This study analyzes the meaning of 'Borderness dismantling' as a molting the center of the world of God, center of Ideology, center of ration in the pluralized and center-cracked world. and also means vague border, no limitation, and overcoming, which make people participate together to overcome the estrangement. The process of study inquire into the phenomenon of fragmentization, indeterminacy, continuitiness, hybridization, mutual penetration, Rhizome and complex allegorization(the process of humanization) Looking back of architectural history, in the origin of those phenomenon, there is the etching works of Piranesi. Many contemporary architects had been affected by his works, and re-interpret and make come true of his visions. This study analyze the meanings of his working process and consequences on contemporary architecture.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.34 no.4
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• pp.95-102
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• 2018

In this study, existential thoughts in Frank Lloyd Wright's notion of nature were investigated. Wright, a modern architect, presented the idea of creating organic architecture in harmony with nature. His naturalistic romanticism is considered to be the original inspiration for his concept of organic architecture. However, his understanding of architecture in harmony with nature stems from existential ideas in his notion of nature, including humanity. The proposed study analyzes his existential beliefs through his speeches and writings in four categories-love of nature, thoughts of abstract and concrete, nature as being intrinsic and "becoming," and thoughts on science and art. Our analyses reveal that, on the one hand, Wright was inspired by thoughts of naturalistic romanticism born from his disillusionment with city life and an urge to seek life in nature, while, on the other, he also believed that real nature is intrinsic to humans and manifests itself in the very core of their being. He sought to unite humanity, as the interior of nature, with its physical environment, as the exterior of nature. His notion of nature is a "becoming" one that changes with time and space, and varies based on individual humans. In line with these thoughts, Wright sought to create forms not only with respect to mathematical dimensions, but also in consideration of human significance. He considered art and architecture to be born out of an integral thought as a process of humanization. To him, nature is interpreted by humans.