• 한국화재소방학회논문지
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• 제30권1호
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• pp.81-85
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• 2016

Reasonable disaster prevention signs play an important role in guiding evacuation. Through the field investigation on disaster prevention signs in shelters and surrounding areas in Beijing, some problems were found in the using of sign system. Based on the principle of integrated design, evacuation and rescue requirements, it is necesssary to make further study on aspects such as, design of function, systematic consideration, humanization design, as well as the internationalization using. This paper presents an evaluation index system for disaster prevention signs. Such a system is very important for strengthening the independent guiding function of sign systems and improving evacuation efficiency. An effective connection could be realized between the internal environment of buildings, evacuation routes, and emergencey shelters.

• 교육철학
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• 제49호
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• pp.235-270
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• 2013

The aim of this study is to make clear the significance of art education for solving problem in elementary and secondary school. These days, our students have so many negative problems in school and society, for example, school violence, group teasing, group outcasts, arrogate teacher's authority, school collapse, dehumanization get soused excessive and such like. We must support to make humanization through a normal art education and art class. Art, music, physical and literature education is a good methods for human education and mental therapy. The best art education is enlightening the children's imagination and curiosity. To enlighten. in art class at the school, teachers must think about enlightening the children's imagination and curiosity. Aesthetic experience includes creative activities and appreciative activities for human formation. The school must expend effort to increase the art class in each week, because students can change positively in aesthetic experience and aesthetic environment.

• 가정과삶의질연구
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• 제2권1호
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• pp.93-109
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• 1984

The purpose of this study is to investigate the direction and strategy of education for sex role concepts of children on the basis of factor analysis of the present situation in sex role concepts and their formation. Although some maintain that sex role concept of our society has been changing slowly, the traditional sex role concept still dominates and is potentially immanent. the analysis of present condition of our society indicates that the formal as well as informal education are facing with various crucial problems in providing the direction of behavior demanded for carrying out the role. The close analysis of the three theories, psychoanalytic theory , social learning theory, cognitive development theory, lends a support to the laim of the study that cognitive development theory provide an integrated frame of reference for us to see the sex role education analytically Furthermore, the factors which are found to have influences on the formation of sex role have been analyzed in three areas: Family, School and society. 1)The factors in family such as parental behavior of upbringing and their concepts of sex role have a direct relationship with the nature of sex tole concept of children. Therefore, the first step to make children to habe a new type of sex-role conception appropriate for modern societies is to change that of parental conception and attitudes. 2)the quantitative as well as the qualitative aspects of school education showed no exceptional trend from the dominant conception of the society, although school are expected to lead the society as formal education institution rather than just reflect the society. The educational activities and contents such as the conceived goal of education for eoch sex, textbook constitation, teaching behavior and sex-role concepts of teacher are found to be still dominated by the traditional sex-role assumption. 3) The social factors that have direct relationship with children's sex-role formation are social and cultural, which include social milieu, condition of employment, family structure and mass-media. Since family and school do not educate the young in a social vacuum. their educational function of sex-role formation are doomed to be limited and determined by these social factors. Unfortunately, the analysis of present conditions showed the dominance of traditional types of sex-role concepts in all these social factors. The education of sex-role concept for children should be treated as one of the most crucial value problems related with many other important problems, such as direction and patterns of behaviors of each sex, the degree of self-development and capabilities, and consequently human right, equality, humanization and the quality of happiness. Neverthless, the analysis of researches on sex-role education which have been surveyed in this study lead to a conclusion that concerted effort to change the education, formal as well as informal should be provided in every aspect of social life. If the sex role education of the past has aimed at the "feminization"of girls which indoctrinate girls into a limited and fixed role of house wives, the new education in the future should be directed foward "humanization" of both sexes which opens the diversity of roles for both boys and girl on equal levels and provide future possibilities in accordance to their individual capabilities and interests.

• 철학연구
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• 제126호
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• pp.85-115
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• 2019

20세기 이후 과학기술의 급속한 발전에 따라 인간의 자연적, 신체적 한계를 기술을 통해 극복하려는 시도가 점점 가속화된다. 트랜스휴머니즘은 이러한 인간의 기술적 시도를 적극적으로 지지하고 긍정하는 운동이다. 그러나 트랜스휴머니즘의 기술에 대한 낙관적 태도는 이를 통해 인간의 자연적 본성이 파괴되고, 인간의 가치가 심하게 훼손될 수 있다는 반대론자들의 강한 저항에 부딪히게 된다. 트랜스휴머니즘 논란의 초점은 기술이 인간에게 어떠한 의미를 갖느냐는 것이다. 그러나 트랜스휴머니즘의 정확한 이해를 위해서는 우선 기술과 인간이 한데 어우러져 있는 우리의 '생활세계'에 대한 고찰이 선행되어야 한다. 생활세계는 모든 인간의 실천적 활동의 바탕이 되면서 동시에 이의 산물을 그 자체 안에 포괄하는 개방적이고 포용적인 세계이다. 후설에 따르면 생활세계속으로 인간의 산물이 포함되는 과정은 일종의 '친숙화' 과정으로서 이를 통해 특정 이론이나 기술 등은 생활세계 속에서 우리의 삶과 조화로운 결합을 이루면서 동시에 상대화된다. 이러한 기술의 생활세계로의 편입 및 친숙화는 기술의 인간화 과정이며, 인간과 생활세계의 유한성과 조응하는 과정으로도 볼 수 있다. 이런 맥락에서 볼 때, 트랜스휴머니즘적 시도는 생활세계 속의 인간의 자연스러운 실천의 과정으로서 이에 대해 지나치게 우려할 것도 아니지만 또 과도하게 맹신해서도 안 될 것이다.

• Journal of Microbiology
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• 제45권6호
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• pp.572-577
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• 2007

To enhance therapeutic potential of murine monoclonal antibody, humanization by CDR grafting is usually used to reduce immunogenic mouse residues. Most humanized antibodies still have mouse residues critical for antigen binding, but the mouse residues may evoke immune responses in humans. Previously, we constructed a new humanized version (AKA) of mouse CC49 antibody specific for tumor-associated glycoprotein, TAG-72. In this study, to select a completely human antibody light chain against TAG-72, guided selection strategy using phage display was used. The heavy chain variable region (VH) of AKA was used to guide the selection of a human TAG-72-specific light chain variable region (VL) from a human VL repertoire constructed from human PBL. Most of the selected VLs were identified to be originated from the members of the human germline VK1 family, whereas the VL of AKA is more homologous to the VK4 family. Competition binding assay of the selected Fabs with mouse CC49 suggested that the epitopes of the Fabs overlap with that of CC49. In addition, they showed better antigen-binding affinity compared to parental AKA. The selected human VLs may be used to guide the selection of human VHs to get completely human anti-TAG72 antibody.

• 한국콘텐츠학회논문지
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• 제15권8호
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• pp.85-95
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• 2015

본 연구는 제주신화 <차사본풀이>를 소재로 하는 문화콘텐츠를 분석하여 변용 양상을 살펴보았다. <차사본풀이>는 저승 여행을 통해 난제를 해결하고 저승사자가 되는 강림의 영웅 서사를 보여주고 있으며, 우리나라의 저승관이 잘 반영되어 있어 원형 서사로서 콘텐츠적 가치를 갖고 있다. <차사본풀이>를 소재로 한 문화콘텐츠들은 '영웅 서사의 충실한 재현'(저승사자가 된 강림도령), '인간화를 통한 서사의 비극적 전환'(집으로 가는 길), '전통과 현대적 요소의 융합을 통한 서사의 확장'(신과 함께), '시대적 트렌드를 반영한 독창적인 세계관'(고스트 메신저)의 특징을 보여주고 있었다. 이러한 분석을 통해 <차사본풀이>의 '저승을 방문한 영웅' 모티프가 다양하게 변형되면서 각 장르의 콘텐츠로 전환되고 있음을 알 수 있었다.

• 정신신체의학
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• 제1권1호
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• pp.14-24
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• 1993

The author discussed present problems and future prospects of psychosomatic medicine in clinical, educational, research, and social aspects. In general, psychosomatic field. particularly. consultation-liaison(C-L) psychiatry in Korea seems to remain on early developmental phase. However, positive change in the general publics' and societal view of psychiatry, specialization of medicine and development of medical technology, implementation of delivery system in medical care could contribute to development of this field. In future, clinically, liaison activity will be more activated. and this field will be developed as main subspecialty of psychiatry. In addition. C-L psychiatry will be subspecialized. and prevention and humanization of medical care could be more emphasized. In education. the main place of education for medical students and psychiatric residents will be changed from closed ward to general ward in which consultation-liaison activity can be performed. In research. consultation liaison model suitable for Koreans will be developed and studies on disease mechanism will be more promoted. In social aspects, this field could influence the general publics' view of psychiatry and change the whole areas of medicine and society toward integration. In order to achieve these goals, medical insurance system and cost relevant to C-L activity should be essentially improved.

• Journal of Plant Biotechnology
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• 제36권4호
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• pp.309-319
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• 2009

Transgenic plant cell cultures for the production of biopharmaceuticals including monoclonal antibodies, recombinant proteins have been regarded as an alternative platform in addition to traditional microbial fermentation and mammalian cell cultures. Plant-made pharmaceuticals (PMPs) have several advantages such as safety, cost-effectiveness, scalability and possibility of complex post-translational modifications. Increasing demand for the quantity and diversity of pharmaceutical proteins may accelerate the industrialization of PMP technology. Up to date, there is no plant-made recombinant protein approved by USFDA (Food and Drug Administration) for human therapeutic uses due to the technological bottlenecks of low expression level and slight differences in glycosylation. Regarding expression levels, it is possible to improve the productivity by using stronger promoter and optimizing culture processes. In terms of glycosylation, humanization has been attempted in many ways to reduce immune responses and to enhance the efficacy as well as stability. In this review article, all these respects of transgenic plant cell cultures were summarized. In addition, we also discuss the general characteristics of plant cell suspension cultures related with bioreactor design and operation to achieve high productivity in large scale which could be a key to successful commercialization of PMPs.

• 한국실내디자인학회논문집
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• 제15권1호
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• pp.3-11
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• 2006

After the 60's, The discourse of the Art of Reception, semiotics, and epistemology have been made steady progress. Especially, the Art of Reception which emphasizes the role of reader in the process of understanding the text, had made the significant role of the Border Dismantling in the Architecture. Its concept can be difined as the free interpretation of each individuals on the art works, that abhors the one-directional systems between reader and writer. This study analyzes the meaning of 'Borderness dismantling' as a molting the center of the world of God, center of Ideology, center of ration in the pluralized and center-cracked world. and also means vague border, no limitation, and overcoming, which make people participate together to overcome the estrangement. The process of study inquire into the phenomenon of fragmentization, indeterminacy, continuitiness, hybridization, mutual penetration, Rhizome and complex allegorization(the process of humanization) Looking back of architectural history, in the origin of those phenomenon, there is the etching works of Piranesi. Many contemporary architects had been affected by his works, and re-interpret and make come true of his visions. This study analyze the meanings of his working process and consequences on contemporary architecture.

• 대한건축학회논문집:계획계
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• 제34권4호
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• pp.95-102
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• 2018

In this study, existential thoughts in Frank Lloyd Wright's notion of nature were investigated. Wright, a modern architect, presented the idea of creating organic architecture in harmony with nature. His naturalistic romanticism is considered to be the original inspiration for his concept of organic architecture. However, his understanding of architecture in harmony with nature stems from existential ideas in his notion of nature, including humanity. The proposed study analyzes his existential beliefs through his speeches and writings in four categories-love of nature, thoughts of abstract and concrete, nature as being intrinsic and "becoming," and thoughts on science and art. Our analyses reveal that, on the one hand, Wright was inspired by thoughts of naturalistic romanticism born from his disillusionment with city life and an urge to seek life in nature, while, on the other, he also believed that real nature is intrinsic to humans and manifests itself in the very core of their being. He sought to unite humanity, as the interior of nature, with its physical environment, as the exterior of nature. His notion of nature is a "becoming" one that changes with time and space, and varies based on individual humans. In line with these thoughts, Wright sought to create forms not only with respect to mathematical dimensions, but also in consideration of human significance. He considered art and architecture to be born out of an integral thought as a process of humanization. To him, nature is interpreted by humans.