• 전기전자학회논문지
• /
• 제26권1호
• /
• pp.36-42
• /
• 2022

본 연구에서는 전기 신호 경로로서의 인체 채널에 대해 임펄스 응답 신호를 이용한 분석 결과를 제시한다. 최근, 인체 통신(human body communications)은 착용형 또는 임플란트형 센서 디바이스 간의 통신 방법으로 인체 영역 통신망(wireless body area networks)을 구성하는 효과적인 접근방법으로 제시되고 있다. 인체 통신 시스템 설계에 중요한 지침인 인체 채널 특성 제공을 위해, 자체 제작한 채널 응답측정장치를 사용하고 용량성 커플링(capacitive coupling) 특성에 적합한 실험환경을 구축하여 측정을 수행하고 그 분석한 결과를 제시한다. 측정 신호에 대한 신호처리 과정으로 임펄스 응답을 효과적으로 추출하여, 0 MHz에서 100 MHz 사이의 주파수 분석을 통해 평균 경로 손실 약 46.8 dB를 제시하고 주파수별 경로 손실 특성을 확인할 수 있다. 또한, 본 연구는 인체 통신 시스템의 수신기 신호 대 잡음비(signal-to-noise ratio) 예측을 위한 수신기 필터의 커패시터와 저항값 변화에 따른 전체 측정 주파수와 기저 대역 신호의 검출 성능 결정에 영향을 주는 3 MHz 이하 대역에서의 상대적인 잡음 전력을 제시하였다.

• 한국자동차공학회논문집
• /
• 제17권4호
• /
• pp.1-9
• /
• 2009

A simplified model of seat-human body is presented to analyze vibrations of human body on a seat of vehicle. The theoretical model having seven degrees-of-freedom is composed of the inter-connected masses, springs and dampers. Until now, evaluation of ride comfort has been usually performed only through vehicle tests. This study aims to complement shortcomings of conventional vehicle tests in evaluation of ride comfort by using the theoretical model. The acceleration values of the human body are obtained from frequency response functions of the theoretical model. Thereafter, Ride and SEAT indexes are acquired by considering response characteristics of the human body for the 12 axes that are presented in BS 6841. A vehicle test is carried out to measure the acceleration values for the three parts of the human body such as upper body, hip and foot. Ride and SEAT indexes of the vehicle test are also obtained by considering the response characteristics of the human body, of which results are compared with the values from the theoretical model. It is found that the theoretical results are in good agreement with the experimental results.

• 한국소음진동공학회논문집
• /
• 제23권1호
• /
• pp.9-16
• /
• 2013

This paper experimentally deals with the excitation by functional electrical stimulus(FES) and the response of electromyo-potential at the muscles of antebrachial joint in a human body. The excitation of FES, which results in the contraction of the muscles and thus the flection of the joint, shows that the flection angle of the joint is proportional to the magnitude of the stimulus current. The response of electromyo-potential measured according to the FES shows the linearly-proportional relation between the joint torque and the electromyo-potential. The results can be used for active motion of joint rehabilitation.

• 대한인간공학회지
• /
• 제26권1호
• /
• pp.47-53
• /
• 2007

The uncanny valley is a hypothesis about robotics concerning the emotional response of humans to robots and other non-human entities. Although it stands today as one of the robots and synthetic characters, the uncanny valley was speculative and few studies have been performed to test the theory. In two experiments, a total of 183 participants were employed to explore this hypothesis. The results of experiment 1 indicate that the perceived human likeness of a robot is not a key factor causing uncanny valley. And the results of experiments 2 suggest that even if the appearance and motion of a robot become fully human, the emotional response of humans could not reach human-human empathy levels.

• KIEAE Journal
• /
• 제3권2호
• /
• pp.25-32
• /
• 2003

This study deals with the investigation of recognition structure on architectural environment and reconstruction of it by artificial intelligence. To test the possibility of the reconstruction, recognition structure on architectural environment is analysed and each steps of the structure are matched with computational methods. Edge Detection and Neural Network were selected as matching methods to each steps of recognition process. Visual perception system established by selected methods is trained and tested, and the result of the system is compared with that of experiment of human. Assuming that the artificial system resembles the process of human recognition on architectural environment, does the system give similar response of human? The result shows that it is possible to establish artificial visual perception system giving similar response with that of human when it models after the recognition structure and process of human.

• Journal of Microbiology and Biotechnology
• /
• 제30권2호
• /
• pp.187-195
• /
• 2020

To understand the molecular mechanism involved in the survivability of cold-tolerant lactic acid bacteria was of great significance in food processing, since these bacteria play a key role in a variety of low-temperature fermented foods. In this study, the cold-stress response of probiotic Lactobacillus plantarum K25 isolated from Tibetan kefir grains was analyzed by iTRAQ proteomic method. By comparing differentially expressed (DE) protein profiles of the strain incubated at 10℃ and 37℃, 506 DE proteins were identified. The DE proteins involved in carbohydrate, amino acid and fatty acid biosynthesis and metabolism were significantly down-regulated, leading to a specific energy conservation survival mode. The DE proteins related to DNA repair, transcription and translation were up-regulated, implicating change of gene expression and more protein biosynthesis needed in response to cold stress. In addition, two-component system, quorum sensing and ABC (ATP-binding cassette) transporters also participated in cell cold-adaptation process. These findings provide novel insight into the cold-resistance mechanism in L. plantarum with potential application in low temperature fermented or preserved foods.

• Nutrition Research and Practice
• /
• 제9권2호
• /
• pp.117-122
• /
• 2015

BACKGROUND/OBJECTIVES: Curcumin, a major component of the Curcuma species, contains antioxidant and anti-inflammatory properties. Although it was found to induce apoptosis in cancer cells, the functional role of curcumin as well as its molecular mechanism in anti-inflammatory response, particularly in intestinal cells, has been less investigated. The intestine epithelial barrier is the first barrier and the most important location for the substrate coming from the lumen of the gut. SUBJECTS/METHODS: We administered curcumin treatment in the human intestinal epithelial cell lines, T84 and Caco-2. We examined endoplasmic reticulum (ER) stress response by thapsigargin, qPCR of XBP1 and BiP, electrophysiology by wild-type cholera toxin in the cells. RESULTS: In this study, we showed that curcumin treatment reduces ER stress and thereby decreases inflammatory response in human intestinal epithelial cells. In addition, curcumin confers protection without damaging the membrane tight junction or actin skeleton change in intestine epithelial cells. Therefore, curcumin treatment protects the gut from bacterial invasion via reduction of ER stress and anti-inflammatory response in intestinal epithelial cells. CONCLUSIONS: Taken together, our data demonstrate the important role of curcumin in protecting the intestine by modulating ER stress and inflammatory response post intoxication.

• 한국응용과학기술학회지
• /
• 제39권1호
• /
• pp.84-95
• /
• 2022

본 연구는 스포츠 휴먼브랜드의 굿즈상품(Goods) 가치, 감정반응(PAD), 소비 행동 간 일어나는 현상을 분석하기 위해 2021년 10월 18일~2022년 1월 12일까지 온라인 서베이(URL), DM, E-mail 등을 활용하여 371명을 편의 표준추출법으로 표집하였으며, 불성실한 응답자 51명을 제외한 유효 표본 320명을 인과 관계(SEM)를 적용하여 분석하였다. 첫째, 휴먼 브랜드의 굿즈 가치는 감정반응에 정(+)의 영향으로 가설이 채택되었다. 둘째, 감정반응은 소비 행동에 정(+)의 영향을 미치는 것으로 가설이 채택되었다. 셋째, 휴먼 브랜드의 굿즈 가치는 소비 행동에 정(+)의 영향을 미치며 부분적으로 가설이 채택되었다. 마지막으로 굿즈상품(goods) 가치와 소비 행동의 관계에서 감정반응의 간접효과는 통계적으로 유의 의미한 것으로 나타났다.

• Journal of Microbiology and Biotechnology
• /
• 제26권7호
• /
• pp.1190-1197
• /
• 2016

The acid response of Bifidobacterium longum subsp. longum BBMN68 has been studied in our previous study. The fab gene, which is supposed to be involved in membrane fatty acid biosynthesis, was demonstrated to be induced in acid response. In order to investigate the relationship between acid response and cell membrane fatty acid composition, the acid adaptation of BBMN68 was assessed and the membrane fatty acid composition at different adaptation conditions was identified. Indeed, the fatty acid composition was influenced by acid adaptation. Our results showed that the effective acid adaptations were accompanied with decrease in the unsaturated to saturated fatty acids ratio (UFA/SFA) and increase in cyclopropane fatty acid (CFA) content, which corresponded to previous studies. Moreover, both effective and non-effective acid adaptation conditions resulted in decrease in the C_18:1 cis-9/C_18:1 trans-9 ratio, indicating that the C_18:1 cis-9/C_18:1 trans-9 ratio is associated with acid tolerance response but not with acid adaptation response. Taken together, this study indicated that the UFA/SFA and CFA content of BBMN68 were involved in acid adaptation and the C_18:1 cis-9/C_18:1 trans-9 ratio was involved in acid tolerance response.

• IMMUNE NETWORK
• /
• 제23권2호
• /
• pp.19.1-19.10
• /
• 2023

Endemic human coronaviruses (HCoVs) have been evidenced to be cross-reactive to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although a correlation exists between the immunological memory to HCoVs and coronavirus disease 2019 (COVID-19) severity, there is little experimental evidence for the effects of HCoV memory on the efficacy of COVID-19 vaccines. Here, we investigated the Ag-specific immune response to COVID-19 vaccines in the presence or absence of immunological memory against HCoV spike Ags in a mouse model. Pre-existing immunity against HCoV did not affect the COVID-19 vaccine-mediated humoral response with regard to Ag-specific total IgG and neutralizing Ab levels. The specific T cell response to the COVID-19 vaccine Ag was also unaltered, regardless of pre-exposure to HCoV spike Ags. Taken together, our data suggest that COVID-19 vaccines elicit comparable immunity regardless of immunological memory to spike of endemic HCoVs in a mouse model.