• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2015년도 춘계 종합학술대회 논문집
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• pp.125-126
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• 2015

According to the provisions of the United Nations, the proportion was 65 years of age or older population is 7% more than in the total population aged society. Due to the rapid decrease fertility and medical technologies and the improvement of living standards, the average life expectancy has emerged as an aging society. In the case of our country, and in 2011 the proportion of the population aged 65 and over 11.4%, the future is even faster aging rate is expected to launch in 2026, the super aged society. The days went by relying on caring for personal piety. Nursing crime is often due to the patriarchal family culture and afford. To care for patients with severe human or plant in the home, not to assume that society. Expanding the scope of long-term care insurance service person and the family burden reduced through measures to apply for health insurance, nursing care can prevent crime.

• BMB Reports
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• 제35권5호
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• pp.513-517
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• 2002

We describe a new method for identifying the sequences that signal the start of translation, and the boundaries between exons and introns (donor and acceptor sites) in human mRNA. According to the mandatory keyword, ORGANISM, and feature key, CDS, a large set of standard data for each signal site was extracted from the ASCII flat file, gbpri.seq, in the GenBank release 108.0. This was used to generate the scoring matrices, which summarize the sequence information for each signal site. The scoring matrices take into account the independent nucleotide frequencies between adjacent bases in each position within the signal site regions, and the relative weight on each nucleotide in proportion to their probabilities in the known signal sites. Using a scoring scheme that is based on the nucleotide scoring matrices, the method has great sensitivity and specificity when used to locate signals in uncharacterized human genomic DNA. These matrices are especially effective at distinguishing true and false sites.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.941-946
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• 2005

In this paper an active random noise control using adaptive learning rate neural networks is presented. The adaptive learning rate strategy increases the learning rate by a small constant if the current partial derivative of the objective function with respect to the weight and the exponential average of the previous derivatives have the same sign, otherwise the learning rate is decreased by a proportion of its value. The use of an adaptive learning rate attempts to keep the learning step size as large as possible without leading to oscillation. It is expected that a cost function minimize rapidly and training time is decreased. Numerical simulations and experiments of active random noise control with the transfer function of the error path will be performed, to validate the convergence properties of the adaptive learning rate Neural Networks. Control results show that adaptive learning rate Neural Networks control structure can outperform linear controllers and conventional neural network controller for the active random noise control.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6083-6086
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• 2012

Background: The aim of this study was to screen for human papillomavirus (HPV) infections in head and neck squamous cell carcinomas (HNSCCs) using P16 immunostaining. Materials and Methods: A retrospective study was performed on 150 samples from patients diagnosed with HNSCCs. HPV status was determined using $p16^{INK4A}$. Results: 31 of the 150 (20.7%) HNSCCs were HPV positive. Conclusions: A large proportion of HNSCCs in Sudan are associated with HPV infection. The fact that the prevalence of HPV is high among Sudanese patients with head and neck cancers (HNC) has obvious implications for vaccine therapy.

• 건축역사연구
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• 제6권3호
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• pp.145-154
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• 1997

Le Corbusier had developed the Modulor replacing the Regulating Lines in the 1930's and 1940's. The lines can not produce lyrical ideas or creational concept but make plastic dimension pure only to keep in balance. First, the Grid of Proportions was developed and then the Modulor 1. The Modulor originated in one square, double square, the two golden means added or subtracted, the place of the right angle, human dimension, the Fibonacci series and divided Red series and Blue series. He developed the Modulor 2 for a reconciliation between the foot-and-inch system and the metre. As Corbusier devoted himself to a social and industrial problem, he was sure that a transcendental universality be in cosmos including a human being. His dream was to creat a orderly and harmonious utopia. What intrinsic harmony between Cosmos, nature and a human being be realized by mathematic order was the reason he hinted himself to the proportion.

• 대한지역사회영양학회지
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• 제16권6호
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• pp.771-781
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• 2011

The objective of this study was to assess the reliability and validity of food security measures, which was developed based on the US household food security survey module (US HFSSM) with content validity in the Korean population. The reliability and validity were assessed by internal consistency, construct validity and criterion-related validity. The study included 446 households. Among those, 46.2% were households with children. The proportion of food insecure households was 33.3%. Among those, 35.4% and 64.6% households were food insecure with hunger and without hunger, respectively. The Cronbach's alpha coefficients were 0.84 and the infit value by the Rasch model analysis ranged from 0.68 to 1.43. The scale item response curves by food insecurity severity explained well the nature and characteristics of food security, indicating the highest proportion of "yes" for the items on diet quality, followed by those with diet quantity. The result of criterion-related validity showed that food insecurity status was significantly related in a dose-response manner with the household income level, food expenditure, subjective health state, subjects' educational level. Household food security status was also related to dietary diversity regarding protein foods, fruits and fruit juice, and milk and dairy product. These findings suggest that the food security instrument is reliable and valid and would be used to assess food security status in the Korean population.

• Journal of Ginseng Research
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• 제13권2호
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• pp.242-247
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• 1989

The effect of ginseng extract and sodium ascorbate (vitamin C) administered separately or in combination on the some cancer cells cultured in vitro have been examined. Mouse leukemic cells (L1210 and P388), human rectal cancer cells (HRT-18) and human colon cancer cells (HCT-48) were used for the experiment. When given separately, the growth rate for each kind of cancer cell was inhibited In proportion to the concentration of ginseng extract or vitamin C. The inhibitory effect on the growth rate of the cancer cells was stronger in ginseng extract than in vitamin C except for the HCT-48 cells. Based on the cytotoxic activity, combined administration of ginseng extract and vitamin C demonstrated a synergistic inhibition of cancer cell growth. The cytotoxic activities of ginseng extract and vitamin C on the mouse leukemic cells were more sensitive than on human colon cancer cells. And the sensitivity of cytotoxic activity was somewhat different in different cancer cell lines.

• KIEAE Journal
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• 제5권2호
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• pp.51-62
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• 2005

The purpose of this study is to calculate the size of unit space of the classroom in elementary school. The curriculum of Elementary school has changed since 1960. It has been reflected the architectural plan of classroom of the nationwide elementary school. However the Ministry of Education repealed the statute about the facilities of the schools on September in 1997 and the new education curriculum-the 7th curriculum-demands various activities in the classroom. So we need to another size of unit space of the classroom in elementary school because the size of unit space will affect the quality of education. This study represent that the size of unit plan is based on the size of human body, education curriculum, the number limit of classroom and teaching tools. It's generally known that a part of human body size has an invariable proportion with human's status. In this study, regression analysis is used to find out a part of the body-size of Korean. Through this analysis, status, age and weight remarkably relate with a part of human body-size. Then the size of unit plan of the classroom is calculated by the part of body-size and the type of desk arrangement.

• Clinical and Experimental Pediatrics
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• 제52권3호
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• pp.269-276
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• 2009

Viruses are the most common cause of lower respiratory tract infections (LRTIs) in infants and young children and are a major public health problem in this age group. Viruses were identified in 54.9-70.4% of hospitalized infants and children with LRTIs in Korea. The viral pathogens identified included respiratory syncytial virus (RSV) A and RSV B, influenza (Inf) A, Inf B, parainfluenza (PIV)1, PIV2, human bocavirus (hBoV), human rhinovirus (hRV), adenovirus (ADV), human metapneumovirus (hMPV), human coronavirus (hCoV)-OC 43, hCoV-229E, hCoV-NL63, hCoV-HKU1, and human enterovirus (hEV). Coinfections with ${\geq}$2 viruses were observed in 11.5-22.8% of children. The occurrence of LRTIs was the highest in the first year of life. The specific viruses are frequently associated with specific clinical syndromes of LRTIs. LRTIs caused by RSV were predominant among younger infants. hRV accounted for a larger proportion of LRTIs in young infants than ADV and hBoV. hMPV was frequently detected in children >24 months old. The number of hMPV infections peaked between February and May, whereas hRV was detected throughout the year. Thus far, hCoV is a less common respiratory pathogen in cases of ALRI and URI in Korean children.

• 한국미생물·생명공학회지
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• 제24권4호
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• pp.472-477
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• 1996

Natural human epidermal growth factor (nhEGF) was purified from pregnant human urine by benzoic acid adsorption, DEAE-Sepharose ion exchange, and immunoaffinity chromatography. The purified nhEGF was further separated into four fractions using Bondapak C$_{18}$ HPLC system. Following characterization by Western blot analysis and double immu- nodiffusion, we found that each fraction corresponds to four derivatives of the nhEGF. For biological analysis of nhEGF, we optimized the labeling time and serum concentration for the incorporatioin of 5-bromo-2'-deoxy uridine (BrdU), a non-radioactive alternative for [$^{3}$H]-thymidine uptake, into NIH 3T3 cells. The DNA synthesis of NIH 3T3 cells was gradually increased at the nhEGF concentrations between 0.1 - 10 ng/ml in the Dulbecco's Modified Eagles Medium (DMEM) containing 0.2% Fetal calf serum (FCS). When we assayed the biological activity of four fractions, the activity of the second fraction was superior to that of the others. Based on the results from the HPLC analysis spiked with recombinant human epidermal growth factor (rhEGF) and amino acid sequencing, we concluded that the second fraction was nhEGF and the other three fractions were the derivatives of nhEGF. In addition, the proportion of nhEGF was approximately 46% is compared with that of the other three derivatives.