• Journal of Microbiology and Biotechnology
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• v.18 no.1
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• pp.145-152
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• 2008

A cell-based in vitro exposure system was developed to determine whether oxidative stress plays a role in the cytotoxic effects of volatile organic compounds (VOCs) such as benzene, toluene, xylene, and chlorobenzene, using human epithelial HeLa cells. Thin films based on cysteine-terminated synthetic oligopeptides were fabricated for immobilization of the HeLa cells on a gold (Au) substrate. In addition, an immobilized cell-based sensor was applied to the electrochemical detection of the VOCs. Layer formation and immobilization of the cells were investigated with surface plasmon resonance (SPR), cyclic voltammetry (CV), and electrochemical impedance spectroscopy (EIS). The adhered living cells were exposed to VOCs; this caused a change in the SPR angle and the VOC-specific electrochemical signal. In addition, VOC toxicity was found to correlate with the degree of nitric oxide (NO) generation and EIS. The primary reason for the marked increase in impedance was the change of aqueous electrolyte composition as a result of cell responses. The p53 and NF-${\kappa}B $ downregulation were closely related to the magnitude of growth inhibition associated with increasing concentrations of each VOC. Therefore, the proposed cell immobilization method, using a self-assembly technique and VOC-specific electrochemical signals, can be applied to construct a cell microarray for onsite VOC monitoring.

• Journal of IKEEE
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• v.19 no.2
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• pp.219-224
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• 2015

Electrical impedance tomography is an imaging technique to reconstruct the internal conductivity distribution based on applied currents and measured voltages in a domain of interest. In this paper, a modified Gauss-Newton method is proposed for conductivity image reconstruction. In the proposed method, the dimension of the inverse term is reduced by replacing the number of elements with the number of measurement data in the conductivity updating equation of the conventional Gauss-Newton method. Therefore, the computation time is greatly reduced as compared to the conventional Gauss-Newton method. Moreover, the regularization parameter is selected by computing the minimum-maximum from the diagonal components of the Jacobian matrix at every iteration. The numerical experiments with several scenarios were carried out to evaluate the reconstruction performance of the proposed method.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38C no.9
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• pp.813-821
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• 2013

In this paper, a vital signal sensor based on impedance variation of resonator is presented. Proposed vital signal sensor can detect the vital signal, such as respiration and heart-beat signal. System is composed of resonator, oscillator, surface acoustic wave (SAW) filter, and power detector. The cyclical movement of a dielectric such as a human body, causes the impedance variation of resonator within the near-field range. So oscillator's oscillation frequency variation is effected on resonator's resonant frequency. SAW filter's skirt characteristic of frequency response can be transformed a small amount of frequency deviation to a large variation. Aim to enhance the existing sensor detection range, proposed sensor operates in 870 MHz ISM band, and detect respiration and heart-beat signal at distance of 120 mm.

• ETRI Journal
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• v.37 no.2
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• pp.204-211
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• 2015

For this study, we designed an implantable rectangular spiral antenna for medical biotelemetry in the Medical Implant Communications Service band (402 MHz to 405 MHz). The designed antenna has a U-shaped loop for impedance matching. The antenna impedance is easily adjusted by controlling the shape and length of the U-shaped loop. Significant design parameters were studied to understand their effects on the antenna performance. To verify the potential of the antenna for the desired applications, we fabricated a prototype and measured its performance in terms of the resonant characteristics and gain radiation patterns of the antenna. In the testing phase, the prototype antenna was embedded in human skin tissue-emulating gel, which was developed to simulate a real operation environment. The measured resonant characteristics show good agreement with the simulations, and the -10 dB frequency band is within the range of 398 MHz to 420 MHz. The antenna exhibits a maximum gain of -22.26 dBi and an antenna efficiency of 0.215%.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.52 no.7
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• pp.421-428
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• 2003

After the cable is installed, many geometric factors, such as bowing types of the cable and the length difference of the cable between each minor section will cause the impedance unbalance between cables. The impedance unbalance will increase or decrease the sheath circulating currents, which are critical to human safety and sustaining the capabilities of electric power. Accordingly, in this paper, a new method is also proposed to reduce the sheath circulating currents and an reduction equipment according to the theory of the new method is developed. The reduction equipment is tested when the cable is on service. The test results show that it can reduce the sheath circulating currents by up to 97.8［%］. This confirms the validation of the new method and the reduction equipment, and assures the safe operation of the transmission cables. In order to illustrate the safe operation of the cable with new current reduction equipment at transient state due to lightning and single line-to-ground fault, extensive simulations have been made. Then the protection scheme of sheath circulating currents reduction equipment is proposed by adopting the new device of RDP(Reduction Device Protector).

• Journal of Biomedical Engineering Research
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• v.28 no.2
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• pp.280-286
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• 2007

The wearable sensor glove was developed using EDA sensors and conducting fabric. EDA(Electro-dermal Activity) signal is an electric response of human skin. There are SIL(Skin Impedance Level) and SIR(Skin Impedance Response) in EDA. SIL consists mostly of a DC component while SIR consists of an AC component. The relationship between drowsiness and the EDA signal is utilized. EDA sensors were made using a conducting fabric instead of AgCl electrodes, for a more suitable, more wearable device. The EDA signal acquisition module was made by connecting the EDA sensor gloves through conductive fabric lines. Also, the EDA signal acquisition module can be connected to a PC that shows the results of the EDA signal processing analysis and gives proper feedback to the user. This system can be used in various applications to detect drowsiness and prevent accidents from drowsiness for automobile drivers.

• International Journal of Fuzzy Logic and Intelligent Systems
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• v.3 no.2
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• pp.244-250
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• 2003

In this paper, the relationship between a slave robot and the uncertain remote environment is modeled as the impedance to generate the virtual force to feed back to the operator. For the control of a tele-operated mobile robot equipped with camera, the tele-operated mobile robot take pictures of remote environment and sends the visual information back to the operator over the Internet. Because of the limitation of communication bandwidth and narrow view-angles of camera, it is not possible to watch the environment clearly, especially shadow and curved areas. To overcome this problem, the virtual force is generated according to both the distance between the obstacle and robot and the approaching velocity of the obstacle. This virtual force is transferred back to the master over the Internet and the master(two degrees of freedom joystick), which can generate force, enables a human operator to estimate the position of obstacle in the remote environment. By holding this master, in spite of limited visual information, the operator can feel the spatial sense against the remote environment. This force reflection improves the performance of a tele-operated mobile robot significantly.

• Journal of Institute of Control, Robotics and Systems
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• v.9 no.8
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• pp.585-591
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• 2003

A virtual force is generated and fed back to the operator to make the teleoperation more reliable, which reflects the relationship between a slave robot and an uncertain remote environment as a form of an impedance. In general, for the teleoperation, the teleoperated mobile robot takes pictures of the remote environment and sends the visual information back to the operator over the Internet. Because of the limitations of communication bandwidth and narrow view-angles of camera, it is not possible to watch certain regions, for examples, the shadow and curved areas. To overcome this problem, a virtual force is generated according to both the distance between the obstacle and the robot and the approaching velocity of the obstacle w.r.t the collision vector based on the ultrasonic sensor data. This virtual force is transferred back to the master (two degrees of freedom joystick) over the Internet to enable a human operator to estimate the position of obstacle at the remote site. By holding this master, in spite of limited visual information, the operator can feel the spatial sense against the remote environment. It is demonstrated by experiments that this collision vector based haptic reflection improves the performance of teleoperated mobile robot significantly.

• Journal of Korean Institute of Industrial Engineers
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• v.39 no.4
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• pp.253-259
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• 2013

Investment scenarios in the transportation network design problem usually contain installation or expansion of multi-mode transportation links. When one applies the mode choice analysis and traffic assignment sequentially for each investment scenario, it is possible that the travel impedance used in the mode choice analysis is different from the user equilibrium cost of the traffic assignment step. Therefore, to estimate the travel impedance and mode choice accurately, one needs to develop a combined model for the mode choice and traffic assignment. In this paper, we derive the inverse demand and the excess demand functions for the multi-mode multinomial logit mode choice function and develop a combined model for the multi-mode variable demand traffic assignment problem. Using data from the regional O/D and network data provided by the KTDB, we compared the performance of the partial linearization algorithm with the Frank-Wolfe algorithm applied to the excess demand model and with the sequential heuristic procedures.

• Journal of Internet Computing and Services
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• v.17 no.2
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• pp.59-65
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• 2016

The result of analyzing the cognitive reaction due to the color environment has been applied to various filed especially in medical field. Moreover, the study about the identification of patient's condition and examination the brain activity by collecting the bio-signal based on the color environment is being actively conducted. Even though, there were a variety of experiments by convention the color environment using a light or LED color, it still has a problem that affects the psychological information. Therefore, our proposed system using a HMD (Head Mounting display) to provide a completed color environment condition. This system uses the BMS(Biomedical System) to collect the biometric information which responds to the specific color condition and the human body response information can be measured by the development the Memory and Attention test on Mobile phone. The collection of Biometric information includes electro cardiogram(ECG), respiration, oxygen saturation (Sp02), Bio-impedance, blood pressure will store in the database. In addition, we can verify the result of the human body reaction in the color environment by Memory and Attention application. By utilizing the reaction of the human body information that is collected thought the proposed system, we can analyze the correlation between the physiological information and the color environment. And we also expect that this system can apply to the medical diagnosis and treatment. For future work, we will expand the system for prediction and treatment of Alzheimer disease by analyzing the visualization data through the proposed system. We will also do evaluation on the effectiveness of the system for using in the rehabilitation program.