• Asian Journal of Innovation and Policy
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• 제8권2호
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• pp.180-207
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• 2019

This article explores the historical evolutionary process of the biopharmaceutical industry of Korea, and how intentional and unintentional policy interventions have triggered the creation of the industry's system dynamics and paved the way for the generation of a few global leading products, including biosimilar, as well as next-generation therapeutics of gene and cell. The policies cover the simple technology transfer of API synthesis to overcome the endemic parasitic disease, new substance patent adoption and new drug development consortia, human resource development, various national initiatives influenced by the Human Genome Project, and venture promotion schemes. The scope and implementation tools under these policies have been aligned and refined to transform traditional fine chemical-based pharmaceuticals, to stimulate large companies' participation and to create technology-based venture companies in the biopharma business of Korea.

• 한국실내디자인학회논문집
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• 제22권3호
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• pp.100-107
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• 2013

In smart era, concept of User experience has been an important issue both in academic and practical areas in recent years. Interactive space became one of the major design paradigms. For elevating the interactive effect, we need user?centered design methodology which uses the influential factors on the interactivity. As, well developed information technology made a lot of changes to various fields of our society, interactive space with the concept of HCI became a big issue in environmental design field. In this interactive space, various types of informative factors of the given space are sent using sensor and computer networking technology to the main system. So, a user's movement in the space in more than just a movement itself-user's movement now forms a important spatial structure that leads the narrative of the space. in this research, I will come up with the problems that the interactive space has right now, and analyze what the public space must have, and combine them with interactive space by HCI theory. architecture space is not the old space adapting digital technology. In order to take the role as new space paradigm. environment and technology, it has to develop technology continuously and experimental space at the same time. It must have co-evolution of architecture space field and others through organic network. by that, the evolution of space will be in the way that combines space which is responded to human emotion and user centric human friendly.

• 가정과삶의질연구
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• 제24권4호
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• pp.51-73
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• 2006

The purpose of this study is to introduce the evolution of corporate family-friendly policies and programs, a recent business issue throughout the world. In addition, this study suggests implications for a corporate reference guide to work-family policies and programs by providing a comparative analysis of the typical stages of development of U.S. corporate family-friendly policies and programs, and by presenting model initiatives of Korean and American family-friendly companies. Just as technological changes at the time of the Industrial Revolution altered the relationship between workers and their work, more recent technological advances have again transformed this relationship, offering the promise of a society in which work demands a smaller portion of the worker's time and permitting the worker more freedom and control over work conditions. These new work arrangements have the promise of producing a new paradigm for work and family, based on which many industrialized nations have developed family-friendly policies already. Family-friendly policies and programs can be grouped into four discernable stages in the evolution of a corporate work-family agenda. According to these stages, most companies in Korea are in the predevelopment stage or stage 1. Development of scales to assess company family-friendliness is needed to create a family-friendly workplace environment, policies, and programs. It is critical that companies have champions who have the vision to step out in kent, and the determination to ensure that the family-friendly programs are solidly grounded. Companies should develop their work-family initiatives as an integral part of a program for managing diversity focusing on needs of women and minority employees.

• 대한전자공학회논문지TC
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• 제49권5호
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• pp.91-98
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• 2012

최근 국내외 주요 이동통신 사업자들이 본격적으로 4G 무선표준 방식인 LTE (Long Term Evolution) 서비스를 시작 하면서 LTE 방식을 지원하는 이동단말의 MIMO (Multi Input-Multi Output) OTA (Over The Air) 성능 평가 방법의 필요성이 중요해 지고 있다. 본 논문에서는 3GPP (3rd Generation Partnership Project)에서 논의되고 있는 MIMO OTA 시스템에서의 LTE 이동 단말기의 핸드 효과에 의한 안테나의 특성변화를 이론 및 실험적으로 검증하였다. 핸드 효과에 의한 LTE 이동 단말기의 성능은 MIMO OTA 시스템에서의 LTE PDSCH throughput 비교를 통해 link level에서 확인하였다.

• 전자통신동향분석
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• 제14권4호통권58호
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• pp.1-9
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• 1999

In this paper, we summarize the lessons learned from the applications of the software reliability engineering to a large-scale software project. The considered software is the software system of the TDX-10 ISDN switching system. The considered software consists of many components, called functional blocks. These functional blocks serve as the unit of coding and test. The software is continuing to be developed by adding new functional blocks. We are mainly concerned with the analysis of the effects of these software components to software reliability and with the analysis of the reliability evolution. We analyze the static characteristics of the software related to software reliability using failure data collected during system test. We also discussed a pattern which represents a local and global growth of the software reliability as version evolves. To find the pattern of software of the TDX-10 ISDN system, we apply the S-shaped model to a collection of failure data sets of each evolutionary version and the Goel-Okumoto (G-O) model to a grouped overall failure data set. We expect this pattern analysis will be helpful to plan and manage necessary human/resources for a new similar software project which is developed under the same developing circumstances by estimating the total software failures with respect to its size and time.

• Genomics & Informatics
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• 제6권1호
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• pp.44-49
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• 2008

Protein kinase C (PKC) is a family of kinases involved in the transduction of cellular signals that promote lipid hydrolysis. PKC plays a pivotal role in mediating cellular responses to extracellular stimuli involved in proliferation, differentiation and apoptosis. Comparative analysis of the PKC-${\alpha},{\beta},{\varepsilon}$ isozymes of 200 recently sequenced microbial genomes was carried out using variety of bioinformatics tools. Diversity and evolution of PKC was determined by sequence alignment. The ser/thr protein kinases of Streptomyces coelicolor A3 (2), is the only bacteria to show sequence alignment score greater than 30% with all the three PKC isotypes in the sequence alignment. S.coelicolor is the subject of our interest because it is notable for the production of pharmaceutically useful compounds including anti-tumor agents, immunosupressants and over two-thirds of all natural antibiotics currently available. The comparative analysis of three human isotypes of PKC and Serine/threonine protein kinase of S.coelicolor was carried out and possible mechanism of action of PKC was derived. Our analysis indicates that Serine/ threonine protein kinase from S. coelicolor can be a good candidate for potent anti-tumor agent. The presence of three representative isotypes of the PKC super family in this organism helps us to understand the mechanism of PKC from evolutionary perspective.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제10권12호
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• pp.5422-5441
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• 2016

Despite the abundant literature in the field, there is still the need to find a time-efficient, highly accurate, easy to deploy and robust localization algorithm for real use. The algorithm only involves minimal human intervention. We propose an enhanced Received Signal Strength Indicator (RSSI) based positioning algorithm for Wi-Fi capable devices, called the Dynamic Weighted Evolution for Location Tracking (DWELT). Due to the multiple phenomena affecting the propagation of radio signals, RSSI measurements show fluctuations that hinder the utilization of straightforward positioning mechanisms from widely known propagation loss models. Instead, DWELT uses data processing of raw RSSI values and applies a weighted posterior-probabilistic evolution for quick convergence of localization and tracking. In this paper, we present the first implementation of DWELT, intended for 1D location (applicable to tunnels or corridors), and the first step towards a more generic implementation. Simulations and experiments show an accuracy of 1m in more than 81% of the cases, and less than 2m in the 95%.

• 한국지능시스템학회논문지
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• 제20권4호
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• pp.522-527
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• 2010

본 논문은 유방 조영 영상의 대비를 향상시키기 위해 새로운 호모몰픽 필터(MBHF)를 제안한다. 제안된 필터는 영상을 형체적으로 다수 분할한 후 각각의 형체 즉, 서브-밴드에 대해 그 구성요소와 이득이 차분진화를 통해 최적의 값을 갖도록 설계된다. 결과 분석을 통해 제안된 방법이 영상 대비를 향상시키는 것을 보이며 웨이블렛 기반의 호모몰픽 필터와 성능이 비교된다. 성능평가 기준으로는 인간의 시각적 인식을 고려한 WPSNR(Weighted Peak Signal to Noise Ratio)을 사용한다.

• Asian Journal of Innovation and Policy
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• 제10권3호
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• pp.355-379
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• 2021

This study examined the evolution of S&T Basic Acts in Korea from the Science and Technology Promotion Act (1967) through the Special Act on STI (1997) to the Framework Act on Science and Technology (2001) in the following aspects: 1) comprehensive plans, 2) coordination mechanisms for S&T policies, 3) enforcement of R&D programs and performance diffusion, 4) promotion of human resources, 5) and S&T investment and budgeting. Before the Framework Act on S&T was enacted in 2001, critical issues were found in establishing S&T master plans, promotion of R&D programs, comprehensive coordination mechanisms, and R&D budgeting. The three Basic Acts have expanded the scope of regulation over time to cover the entire cycle of the S&T process. They concern a wide range of issues, including creating a basis for scientific and technological development, S&T promotion, disseminating and commercializing research outcomes, and preventing adverse effects from science and technology. The content of the Basic Acts has evolved in response to changes in the political, economic, and social environment of Korean industry during the past five decades.

• Advances in nano research
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• 제12권3호
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• pp.319-336
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• 2022

Evaluating the temporal and spatial changes in the ecosystem service value (ESV) of the Sanjiangyuan Nature Reserve is important for understanding the impact of human activities on natural ecosystem and guiding ecosystem restoration and environmental pollution control. In this study, remotely sensed land-cover data and the equivalent factor method were used to analyze the spatiotemporal evolution characteristics of the ESV in Sanjiangyuan Nature Reserve from 1992 to 2015, and regression analysis was employed to determine the factors driving changes in the ESV. The results show that grassland was the main type of ecosystem in the study area, and the transformation of grassland into bare areas was the primary change in land cover. Additionally, the ESV in the study area first decreased and then increased, with an annual growth rate of 0.69%. The ESV mainly increased in the north of the Yellow River's source area, and mainly decreased in the northwest of the Yangtze River's source area. Finally, the gross output value of agriculture, urbanization rate and proportion of secondary industry were found to be the main factors driving the ESV in the study area.