• Title/Summary/Keyword: human evolution

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Molecular prophage typing of Staphylococcus aureus isolates from bovine mastitis

  • Ko, Dae-Sung;Seong, Won-Jin;Kim, Danil;Kim, Eun-Kyung;Kim, Nam-Hyung;Lee, Chung-Young;Kim, Jae-Hong;Kwon, Hyuk-Joon
    • Journal of Veterinary Science
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    • v.19 no.6
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    • pp.771-781
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    • 2018
  • Staphylococcus aureus is one of the major pathogens causing bovine mastitis and foodborne diseases associated with dairy products. To determine the genetic relationships between human and bovine or bovine isolates of S. aureus, various molecular methods have been used. Previously we developed an rpoB sequence typing (RSTing) method for molecular differentiation of S. aureus isolates and identification of RpoB-related antibiotic resistance. In this study, we performed spa typing and RSTing with 84 isolates from mastitic cows (22 farms, 72 cows, and 84 udders) and developed a molecular prophage typing (mPPTing) method for molecular epidemiological analysis of bovine mastitis. To compare the results, human isolates from patients (n = 14) and GenBank (n = 166) were used for real and in silico RSTing and mPPTing, respectively. Based on the results, RST10-2 and RST4-1 were the most common rpoB sequence types (RSTs) in cows and humans, respectively, and most isolates from cows and humans clearly differed. Antibiotic resistance-related RSTs were not detected in the cow isolates. A single dominant prophage type and gradual evolution through prophage acquisition were apparent in most of the tested farms. Thus, RSTing and mPPTing are informative, simple, and economic methods for molecular epidemiological analysis of S. aureus infections.

A Study on the Extension and Change of the Ethics of Donghak (동학(東學) 윤리관의 확장과 변화)

  • Yi, Jong Woo
    • The Journal of Korean Philosophical History
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    • no.30
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    • pp.37-57
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    • 2010
  • Su-un 'sicheonju' is emphasised transcendency of god that it is sincerity, earnestness and belief in the practice ethics. But he is exhibited the ancient sage-kings of ancient propriety and humanity, righteousness, propriety and wisdom. Su-un 'sicheonju' change 'insicheon' of Hae-wol at immanence of god the emphasis. He is exhibited 'sainyeocheon' in the practice ethics. Eu-am is changed 'Innaecheon' more immanence of god the emphasis. He exhibit good the subject of human. It's the change cause research Su-un. He exhibit Confucianism ethics at the same time as point out Confucianism because Hae-wol and Eu-am is changed the emphasis at the subject of human. It is influenced pantheism and the theory of social evolution.

A Study on The Need for AI Literacy According to The Development of Artificial Intelligence Chatbot (인공지능 챗봇 발전에 따른 AI 리터러시 필요성 연구)

  • Cheol-Seung Lee;Hye-Jin Baek
    • The Journal of the Korea institute of electronic communication sciences
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    • v.18 no.3
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    • pp.421-426
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    • 2023
  • Among artificial intelligence convergence technologies, Chatbot is an artificial intelligence-based interactive system and refers to a system that can provide interaction with humans. Chatbots are being re-examined as chatbots develop into NLP, NLU, and NLG. However, artificial intelligence chatbots can provide biased information based on learned data and cause serious damage such as privacy infringement and cybersecurity concerns, and it is essential to understand artificial intelligence technology and foster AI literacy. With the continued evolution and universalization of artificial intelligence, AI Literacy will also expand its scope and include new areas. This study is meaningful in raising awareness of artificial intelligence technology and proposing the use of human respect technology that is not buried in technology by cultivating human AI literacy capabilities.

A Scientometric and Meta-analysis of Rail Infrastructure in Nigeria

  • Awodele, Imoleayo Abraham;Mewomo, Modupe Cecilia
    • International conference on construction engineering and project management
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    • 2022.06a
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    • pp.960-966
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    • 2022
  • Mobility is an essential human need. Human survival and societal interaction depend on the ability to move people and goods. Efficient mobility systems are essential facilitators of economic development. Cities could not exist and global trade could not occur without systems to transport people and goods cheaply and efficiently. Rail has been considered as one of the important components of the transportation infrastructure required to service and improve the performance and productivity of an economy. In Nigeria, the rail infrastructure built by the colonial master several decades ago has been left in a state of total deterioration. This long neglect was occasioned by the failure of the government to pay adequate attention to infrastructure development. There is a vital and urgent need for rail infrastructure development in Nigeria. This study presents a systematic review of the evolution of rail, the current nature of railway infrastructure delivery in Nigeria, and offers possible suggestions on how to achieve an effective and sustainable rail infrastructure delivery in Nigeria. A thorough literature search of academic databases was conducted on current research trends on the subject of railway infrastructure by systematically reviewing selected published articles from reputable research domains. The analysis of the selected articles revealed the following among others (1) the existing railway infrastructure is in a state of mess and not sustainable, and (2), Government's investment/commitment in rail infrastructure seems inadequate compared to what is obtainable in other developed countries. Rail infrastructure development cannot be left to the Federal government of Nigeria to solve on its own; collaboration and participation are required. Government as a matter of priority should devote considerable attention to the development of rail infrastructure to harness the economic potential and transformation that sustainable rail infrastructural projects will provide.

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ACTIVITY-BASED STRATEGIC WORK PLANNING AND CREW MANAGEMENT IN CONSTRUCTION: UTILIZATION OF CREWS WITH MULTIPLE SKILL LEVELS

  • Sungjoo Hwang;Moonseo Park;Hyun-Soo Lee;SangHyun Lee;Hyunsoo Kim
    • International conference on construction engineering and project management
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    • 2013.01a
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    • pp.359-366
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    • 2013
  • Although many research efforts have been conducted to address the effect of crew members' work skills (e.g., technical and planning skills) on work performance (e.g., work duration and quality) in construction projects, the relationship between skill and performance has generated a great deal of controversy in the field of management (Inkpen and Crossan 1995). This controversy can lead to under- or over-estimations of the overall project schedule, and can make it difficult for project managers to implement appropriate managerial policies for enhancing project performance. To address this issue, the following aspects need to be considered: (a) work performances are determined not only by individual-level work skill but also by the group-level work skill affected by work team members, each member's role, and any working behavior pattern; (b) work planning has significant effects on to what extent work skill enhances performance; and (c) different types of activities in construction require different types of work, skill, and team composition. This research, therefore, develops a system dynamics (SD) model to analyze the effects of both individual-and group-level (i.e., multi-level) skill on performances by utilizing the advantages of SD in capturing a feedback process and state changes, especially in human factors (e.g., attitude, ability, and behavior). The model incorporates: (a) a multi-level skill evolution and relevant behavior development mechanism within a work group; (b) the interaction among work planning, a crew's skill-learning, skill manifestation, and performances; and (c) the different work characteristics of each activity. This model can be utilized to implement appropriate work planning (e.g., work scope and work schedule) and crew management policies (e.g., work team composition and decision of each worker's role) with an awareness of crew's skill and work performance. Understanding the different characteristics of each activity can also support project managers in applying strategic work planning and crew management for a corresponding activity, which may enhance each activity's performance, as well as the overall project performance.

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The Evolution of the Science Education Policy for the Gifted, 1968-2012: The Interaction of the Policy of Human Resource in Science and Technology and Education Policy for the Gifted (과학영재교육정책의 진화, 1968-2012: 과학기술인력정책과 영재교육정책의 상호작용)

  • Woo, Saimi
    • Journal of Gifted/Talented Education
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    • v.25 no.2
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    • pp.279-298
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    • 2015
  • This study analyzes the interaction of the policy of human resource in science and technology and the policy of education for the gifted. In Korea, the goals of gifted education seem to have gravitated more toward serving the national perspective of creating a pool of high-quality scientists for economic development, rather than toward helping individuals achieve their educational aspirations and promote their talents. The science education policy for the gifted can be categorized into two: one primarily by the Ministry of Science (MOST) and another by the Ministry of Education (MOE). So far, the policy of science education for the gifted has been written by MOE. Such an imbalance has been created because the two ministries differed in their values and priorities. MOST has designed the science education policy in order to foster the gifted as high-quality human resources in science and technology that can help contribute to economic development. On the other hand, MOE has designed the policy for the gifted with educational equity in mind. Although the policy by MOST had have more influence in implementing overall policies of educating the gifted, the two ministries have interacted and formulated the educational system of gifted in Korea. This study sheds light on the process that MOST has legitimized their science education policy for the gifted by designing it in line with the national and social goals, and has formulated a basis on which the gifted can contribute to R&D for economic development.

UNDERSTANDING OF EPIGENETICS AND DNA METHYLATION (인간 게놈의 Copy Number Variation과 유전자 질환)

  • Oh, Jung-Hwan;Nishimura, Ichiro
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.30 no.2
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    • pp.205-212
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    • 2008
  • Genetic variation in the human genome occurs on various levels; from the single nucleotide polymorphism to large, microscopically visible chromosome anomalies. It can be present in many forms, including variable number of tandem repeat (VNTRs; e.g., mini- and microsatellites), presence/absence of transposable elements (e.g., Alu elements), single nucleotide polymorphisms, and structural alterations (e.g., copy number variation, segmental duplication, inversion, translocation). Until recently SNPs were thought to be the main source of genetic and phenotypic human variation. However, the use of methods such as array comparative genomic hybridization (array CGH) and fluorescence in situ hybridization (FISH) have revealed the presence of copy number variations(CNVs) ranging from kilobases (kb) to megabases (Mb) in the human genome. There is great interest in the possibility that CNVs playa role in the etiology of common disease such as HIV-1/AIDS, diabetes, autoimmune disease, heart disease and cancer. The discovery of widespread copy number variation in human provides insights into genetic variability among populations and provides a foundation for studies of the contribution of CNVs to evolution and disease.

Policy and Strategy for Intelligence Information Education and Technology (지능정보 교육과 기술 지원 정책 및 전략)

  • Lee, Tae-Gyu;Jung, Dae-Chul;Kim, Yong-Kab
    • KIPS Transactions on Computer and Communication Systems
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    • v.6 no.8
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    • pp.359-368
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    • 2017
  • What is the term "intelligence information society", which is a term that has been continuously discussed recently? This means that the automation beyond the limits of human ability in the whole societies based on intelligent information technology is a universalized social future. In particular, it is a concept that minimizes human intervention and continuously pursues evolution to data (or big data) -based automation. For example, autonomous automation is constantly aiming at unmanned vehicles with artificial intelligence as a key element. However, until now, intelligent information research has focused on the intelligence itself and has made an effort to improve intelligence logic and replace human brain and intelligence. On the other hand, in order to replace the human labor force, we have continued to make efforts to replace workers with robots by analyzing the working principles of workers and developing optimized simple logic. This study proposes important strategies and directions to implement intelligent information education policy and intelligent information technology research strategy by suggesting access strategy, education method and detailed policy road map for intelligent information technology research strategy and educational service. In particular, we propose a phased approach to intelligent information education such as basic intelligence education, intelligent content education, and intelligent application education. In addition, we propose education policy plan for the improvement of intelligent information technology, intelligent education contents, and intelligent education system as an important factor for success and failure of the 4th industrial revolution, which is centered on intelligence and automation.

The Origin of Thinking Mind (우리는 왜 생각하는 존재가 되었는가?)

  • Park, Man-joon
    • Journal of Korean Philosophical Society
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    • v.131
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    • pp.131-163
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    • 2014
  • This Paper aims to elaborate on the origin of thinking mind. And this is a cooperative project between philosophy and neuroscience and brain science. I have written this paper in admiration for the achievements of twentieth century neuroscience and brain science, and out of desire to assist the subject in future. Much of the history of modern philosophy, from Descartes and Kant forward, consists of failed models of brain. As Edward O. Wilson precisely said, the shortcoming is not the fault of the philosophers, who have doggedly pushed their methods to the limit, but a straightforward consequence of the biological evolution of the brain. Guiding that investigation down pathways that will illuminate brain research is a task of neuroscience and brain science. Investigating logical relations among concepts is a philosophical task. If we are to understand the neural structures and dynamics that make perception, thought, intentional behaviour possible, clarity about these concepts and categories and their relations is essential. Hence our joint venture of philosophy and science. Sure, it is human beings that perceives, not parts of its brain. And it is human beings that who think and reason, not their brain. But the brain and its activities make it possible for human beings-not for it-to perceive and think, to feel emotions, and to form and pursue projects. Thus We try to investigate and reveal the origin of thinking mind as follow: 1) The difference between chimpanzee and human beings 2) brain and mind 3) the origin of thinking 4) the wisdom of nature.

Historical Introduction of Japanese Wild Mice, Mus musculus, from South China and the Korean Peninsula

  • Nunome, Mitsuo;Suzuki, Hitoshi;Moriwaki, Kazuo
    • Animal Systematics, Evolution and Diversity
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    • v.29 no.4
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    • pp.267-271
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    • 2013
  • In Japan, the wild house mouse Mus musculus consists of two lineages, one from Southeast Asia (Mus musculus castaneus; CAS) and one from northern Eurasia (Mus musculus musculus; MUS). However, the exact origins of the parental lineages are unclear. A recent work using mitochondrial sequences revealed that Japanese CAS and MUS are closely related to haplotypes from South China and the Korean Peninsula, respectively. Recent phylogeographic analyses using nuclear gene sequences have also confirmed a close relationship between Japan and Korea in the MUS component. However, the Japanese CAS components in the nuclear genome are likely to be unique and to differ from those of other CAS territories, including South China. Although the origins are still unresolved, these results allow us to conclude that two areas of the continent, South China and the Korean Peninsula, are the primary source areas of Japanese wild mice and suggest pre-historical introductions associated with certain historical agricultural developments in East Asia.