• Title/Summary/Keyword: human evolution

Search Result 393, Processing Time 0.026 seconds

A Study of Design For Reviving Space through Realizing Place Property (장소성 구현을 통한 공간 재생 디자인 연구)

  • Kim, Hyung Nyun
    • Journal of the Korea Furniture Society
    • /
    • v.26 no.4
    • /
    • pp.398-408
    • /
    • 2015
  • Though the physical environment of life through technological evolution has rapidly improved, the quality of life due to a variety of undesirable environmental issues has been seriously damaging. This study has tried to suggest the positive & sustainable direction of space design which can contribute to improving the quality of human lives by reviving 'place property' which a site itself has, trying to analyze the recycling space which the sustainability has been applied to in a true sense. For this cause, we've tried to draw four 'methods of realizing place property' such as meeting a site, understanding a site, finding the identity of a site, and adding novelty to a site through advanced research. I've tried to suggest the design direction for reviving space which can relieve the artificial aspect of design with pursuing the co-existence with nature on the foundation of realizing 'place property' through case analysis selected on the basis of this, and can express the 'sustainability' through environment-friendly space structures & high efficiency of its function.

Natural Products Targeting Wnt/β-catenin Signaling Pathway

  • Kim, Donghwa;Lee, Sang Kook
    • Natural Product Sciences
    • /
    • v.26 no.2
    • /
    • pp.109-117
    • /
    • 2020
  • The canonical Wnt/β-catenin signaling pathways play an important role in the embryonic development, cell proliferation, differentiation, and adhesion. Therefore, the abnormal activation and repression have been associated with uncontrolled homeostasis in human tissues. In particular, the activation of Wnt signaling is highly correlated with a diverse of diseases including cancer. On this regard, a strategy for targeting Wnt/β-catenin signaling has been employed in the discovery and development of antitumor agents. Herein, the evolution of Wnt signaling and the Wnt inhibitors derived from natural products were briefly summarized in the drug discovery of anticancer agents.

The Strategies for Evolutionary Properties of User Interfaces (진화론적 발전 속성에 따른 UI 진화 전략)

  • Kim, Huhn
    • 한국HCI학회:학술대회논문집
    • /
    • 2006.02b
    • /
    • pp.789-794
    • /
    • 2006
  • UI (User Interface)는 끊임없이 진화한다. 사용자의 새로운 요구 사항을 만족시키기 위해, 기존 UI에 대한 불편 사항을 해결하기 위해, 경쟁 제품의 더 좋은 UI를 따라 잡기 위해, 그리고 새로운 기술로 기존에는 불가능했던 것이 가능해 짐으로 인해, UI는 지속적으로 더 좋은 방향으로 변화하고 있다. 특히 휴대폰과 같이 라이프사이클이 짧은 제품의 UI는 매 제품마다 UI를 변화시킬 수 없기 때문에 기업 입장에서의 전략적인 접근이 중요해 진다. 더욱이 충분한 검증 없이 이루어진 진화의 방향은 사용자가 원하는 방향과 일치하지 않게 되어 오히려 퇴화하는 문제도 발생할 수 있다. 본 논문은 UI가 생성, 유지, 융합, 소멸되어 가는 진화론적 발전 속성 및 그러한 속성에 영향을 주는 요소들을 살펴보고, 라이프사이클이 짧은 제품의 UI를 개선할 때 어떤 전략을 취하는 것이 기업 차원에서 좋은지를 설명한다. UI 진화 전략은 크게 점진적 개선을 추구하는 구릉식 전략과 한번에 도약하는 계단식 전략으로 나눌 수 있다. 위 두 전략들은 사용자 만족도, 개선에 필요한 비용과 그 가치, 개선 후의 리스크 (Risk)에 따라 장단점을 가진다. 결론적으로 본 논문에서는 두 전략 모두 서로 상반되는 장단점을 가지므로, 어느 한 전략을 취하기 보다는 UI 요소의 특성 및 변화의 규모에 따라 두 전략을 혼용하는 전략이 기업 입장에서 최적의 전략임을 주장한다.

  • PDF

PCR Analysis of Four Length-Polmorphic Loci in Korea Population for Genotyping

  • Ryu, Jae-Song;Koo, Yoon-Mo;So, Jae-Seong
    • Biotechnology and Bioprocess Engineering:BBE
    • /
    • v.5 no.3
    • /
    • pp.169-173
    • /
    • 2000
  • On human chromoscomes, a short sequence of DNA is known to repeat a number of times. These are called variable number of tandem repeat (VNTR) or short tandem respeat (STR) which has a short core. VNTR and STR are used in the filed of forensic science, evolution, and anthropology. In this work, we examined allele frequencies of one VNTR (YNZ22) and three STRs (NeuR, D21S11, Humth01) in a korean population sample by polymerase chain reaction (RCP) followed by high-resolution polyacrylamide gel electro-phoresis (PAGE) with silver stain. Subsequently, the polymorphism information content (PIC) was calculated : the hifhest PIC was observed in the NeuR locus (0.95680) and lowest in the Humth01 locus (0.75809).

  • PDF

Settlement and Resettlement in Asia: Migration vs. Empire in History

  • MANNING, Patrick
    • Asian review of World Histories
    • /
    • v.3 no.2
    • /
    • pp.171-200
    • /
    • 2015
  • At its simplest, this essay provides a narrative of migration in Asia since the arrival of Homo sapiens some 70,000 years ago. More fully, it presents the case for conducting long-term, world-historical interpretation for Asia with attention to multiple perspectives, which has become increasingly central to global historical analysis. Following an introductory articulation of the benefits of long-term interpretation, the second section presents a balance of three perspectives-empire, exchange, and migration-as frameworks for interpreting the Asian past. The third section presents further detail on migration in long-term Asian history. The concluding section identifies four changes in patterns of migration during the past two centuries and emphasizes the underlying importance of cross-community migration in long-term human biological and social evolution.

SWCL Extension for Knowledge Representation of Piecewise linear Constraints on the Semantic Web (시맨틱 웹 환경에서의 부분선형 제약지식표현을 위한 SWCL의 확장)

  • Lee, Myungjin;Kim, Wooju;Kim, Hak-Jin
    • Journal of the Korean Operations Research and Management Science Society
    • /
    • v.37 no.4
    • /
    • pp.19-35
    • /
    • 2012
  • The Semantic Web technology, purporting to share, to reuse and to process by machines data stored in the Web environment, incessantly evolves to help human decision making; in particular, decision making based on data, or quantitative decision making. This trend drives researchers to fill the gap with strenuous efforts between the current state of the technology and the terminus of this evolution. The Semantic Web Constraint Language (SWCL) together with SWRL is one of these endeavors to achieve the goal. This paper focuses particularly on how to express the piecewise linear form in the context of SWCL. The importance of this ingredient can be fortified by the fact that any nonlinear expression can be approximated in the piecewise linear form. This paper will also provide the information of how it will work in the decision making process through an example of the Internet shopping mall problem.

Animal Cognition and the Evolution of the Human Brain (동물의 인지능력과 인간 두뇌의 진화)

  • Choe Jae C.
    • Korean Journal of Cognitive Science
    • /
    • v.15 no.4
    • /
    • pp.67-75
    • /
    • 2004
  • 인간이 진화의 산물이라면 인간의 두뇌도 당연히 진화의산물이다. 따라서 인간의 두뇌를 연구하는 데에는 진화적 관점이 필수적으로 요구된다. 그래서 나는 이 짤막한 논문에서 우리 인간을 제외한 다른 동물도 사고의 능력을 갖추고 있다는 사실을 증명해줄 수 있는 직접 또는 간접적 증거들을 제시하고 그러한 정보들이 우리 두뇌의 진화를 이해하는 데 어떤 함의가 있는지 논의하고자 한다. 동물의 인지 능력을 엿볼 수 있는 대표적인 행동들로 도구의 사용, 동물들이 만드는 각종 구조물, 진화의 역사 동안 한번도 전하지 못했던 새로운 문제에 대한 해결책, 속임수, 언어, 그리고 복잡한 사회구조에 대한 이해 등에 대해 동물행동학자들의 관찰 견과를 간략히 소개한다. 아울러 지난 몇 년간 본인이 추진해온 한국영장류 연구소(Institute of Primate Research and Conservation: iPRC)의 건립 계획과 연구 목표를 간략하게나마 밝히고자 한다.

  • PDF

Development Process of Nuclear Power Industry in a Developing Country : Korean Experience and Implications (개발도상국에 있어서 원자력산업의 기술발전과정 분석 : 한국의 경험과 시사점)

  • 홍사균
    • Proceedings of the Technology Innovation Conference
    • /
    • 1999.06a
    • /
    • pp.176-202
    • /
    • 1999
  • Korea has exerted her efforts to assimilate nuclear power technology, and reportedly localized 95 percent of nuclear power technology by 1995. This paper investigates the evolution of nuclear power program in Korea to exploit the development process of the nuclear power industry and key factors for the technological localization of nuclear power plant. In developing countries, an imitative catching-up process can be shown as a course for developing the absorptive capacity of foreign technology, which depends on prior knowledge base and the intensity of effort. The process of technological learning consists of five stages including preparation, implementation of foreign technology, acquisition of peripheral technology, acquisition of core technology, and improvement f foreign technology. Moreover, this paper discusses six essential factors that have influenced the successful achievement of technological localization of nuclear power plants in Korea. They include the role and strategies of the government, the leading role of utility firm, the development and cooperation of the related organizations, the development of human resources and their efforts, market conditions and the assistance of foreign donors, and social conditions. Finally, this paper discusses about implications offered by the Korean experience for other developing countries.

  • PDF

Effect of Irradiation on the Biological System in Plants (식물의 생물학적 시스템에 대한 방사선의 상호작용)

  • Choi, Jong-Il;Kim, Jin-Kyun
    • Journal of Plant Biotechnology
    • /
    • v.40 no.3
    • /
    • pp.111-124
    • /
    • 2013
  • Research on the basic interaction of radiation with biological systems has contributed to human society through various applications in pharmaceutical, medicine, agriculture and other technological developments. In the agricultural sciences and food technology sectors, the last few decades have witnessed a large number of pertinent works regarding the utilization of radiation for evolution of superior varieties of agricultural crops of economic importance. This review presents general information about the effect of radiation on plant specificity, dose response, and benefits. There has been summarized of the effects observed after exposure and influenced by several factors including plant characteristics and radiation features. We also report on the effect of ${\gamma}$-irradiations on plants, focusing on metabolic alterations, modifications of growth and development and changes in biochemical pathways.

Genomic Research as a Means to Understand Bacterial Phylogeny and Ecological Adaptation of the Genus Bifidobacterium (Bifidobacterium의 분자생물학적 연구 동향)

  • Kim, Geun-Bae
    • 한국유가공학회:학술대회논문집
    • /
    • 2007.09a
    • /
    • pp.21-29
    • /
    • 2007
  • The field of microbiology has in recent years been transformed by huge increasing number of publicly available whole-genome sequences. This sequence information has significantly enhanced our understanding of the physiology, genetics, and evolutionary development of bacteria. Among the gastrointestinal microorganisms, bifidobacteria represent important human commensals because of their perceived contribution to maintaining a balanced gastrointestinal tract microbiota. In recent years bifidobacteria have drawn much scientific attention due to their use as live bacteria in numerous food products with various health-related claims. For this reason, these bacteria constitute a growing area of interest with respect to genomics, molecular biology, and genetics. Recent genome sequencing of a number of bifidobacterial species has allowed access to the complete genetic make-up of these bacteria. This review will focus how genomic data has allowed us to understand bifidobacterial evolution, while also revealing genetic functions that explains their presence in the particular ecological environment of the gastrointestinal tract.

  • PDF