• Title/Summary/Keyword: hp(3)

Search Result 908, Processing Time 0.027 seconds

Skin Permeability of Porcine Placenta Extracts and Its Physiological Activities

  • Han, JeungHi;Kim, Mi-Ryung;Park, Yooheon;Hong, Yang Hee;Suh, Hyung Joo
    • Food Science of Animal Resources
    • /
    • v.33 no.3
    • /
    • pp.356-362
    • /
    • 2013
  • We investigated the skin permeability and various biological activities of porcine homogenate of placenta (HP) with the highest protein contents (452.89 ${\mu}g/mg$). The content of protein in subcritical extract of HP (SPE) was decreased from the initial content of 452.9 ${\mu}g/mg$ to 262.7 ${\mu}g/mg$ at 3 h subcritical extract. The contents of amino type nitrogen (A-N) were sharply increased from 35.1 ${\mu}g/mg$ of initial content to 305.9 ${\mu}g/mg$ at 3 h subcritical extract. The HP showed a noticeable activity in terms of antioxidant capacity for ferric reducing antioxidant power (FRAP) assay and especially for 2,2'-Azinobis- (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) method. HP, SPE-0.5, SPE-2 and SPE-3 showed inhibitory effect on elastase activities with an $IC_{50}$ of 46.1, 42.9, 31.6 and 34.7 ${\mu}g/mL$, respectively. SPEs showed more significantly inhibitory effect than HP (p<0.05). The skin permeability of the SPEs was higher than that of the HP. SPE-3 showed highest skin permeation and the permeability was significantly higher than that of HP. SPE-2 also showed significantly higher permeation than HP after 4 h. As expected, increase of extraction time significantly increased skin permeability in the subcritical extract of HP (SPE). From these results, in terms of cost and source availability, porcine placenta extracted with subcritical extraction has advantages over untreated PE and have potential as a cosmetic ingredient.

Utilization of Supercritical Carbon Dioxide for the Preparation of 2-Hydroxypropyl-β-Cyclodextrin Microparticles and Their Inclusion Complexes with Ibuprofen (초임계 이산화탄소를 이용한 2-Hydroxypropyl-β-Cyclodextrin 미립자와 이부프로펜과의 포접복합체 제조)

  • Ryu, Jong-Hoon
    • Clean Technology
    • /
    • v.19 no.3
    • /
    • pp.212-218
    • /
    • 2013
  • The microparticles of 2-hydroxypropyl-${\beta}$-cyclodextrin (HP-${\beta}$-CD) were prepared using aerosol solvent extraction system (ASES) by employing supercritical carbon dioxide as an antisolvent, The effects of various process parameters such as temperature, pressure, solution concentration and solution flow rate on the formation of HP-${\beta}$-CD microparticles were investigated. The HP-${\beta}$-CD microparticles prepared by the ASES process were observed to consist of agglomerates of nano-sized (50-200 nm) particles. When an aqueous solution of ethanol was used as a solvent for HP-${\beta}$-CD, the HP-${\beta}$-CD particles were found to be spherical in shape and to become larger as the water content increased. It was confirmed that the micronization of HP-${\beta}$-CD using the ASES process could enhance the inclusion efficiency of ibuprofen/HP-${\beta}$-CD complexes significantly.

Thiadiazole-thione surfactants: Preparation, flotation performance and adsorption mechanism to malachite

  • Huang, Yaoguo;Liu, Guangyi;Liu, Jun;Yang, Xianglin;Zhang, Zhiyong
    • Journal of Industrial and Engineering Chemistry
    • /
    • v.67
    • /
    • pp.99-108
    • /
    • 2018
  • In this paper, novel thiadiazole-thione surfactants including 5-heptyl-1,3,4-thiadiazole-2-thione (HpSDT), 5-phenyl-1,3,4-thiadiazole-2-thione (PSDT) and 5-(2-hydroxyphenyl)-1,3,4-thiadiazole-2-thione (HPhSDT) were synthesized and originally introduced as collectors in froth flotation. Microflotation tests showed that HpSDT exhibited better flotation response to malachite than PSDT and HPhSDT, as well as excellent flotation selectivity against quartz. The contact angle results inferred that the hydrophobization intensity of these collectors toward malachite was in the order as HpSDT> PSDT> HPhSDT. ${\zeta}$-potential recommended a chemisorption of HpSDT on malachite surfaces. FTIR deduced that cupric or cuprous atoms might bond with the S and N atoms of HpSDT to form a conjugated ring. XPS further gave an additional evidence that HpSDT-Cu(I) complexes were produced on malachite surfaces via combining surface Cu atoms with HpSDT's N and S atoms, with reducing surface Cu(II) to Cu (I). The tighter orientation arrangement on malachite and stronger hydrophobicity rendered HpSDT to possess better flotation affinity toward malachite than PSDT and HPhSDT.

Single Level Adaptive hp-Refinement using Integrals of Legendre Shape Function (적분형 르장드르 형상함수를 이용한 단일 수준 적응적 hp-체눈 세분화)

  • Jo, Jun-Hyung;Yoo, Hyo-Jin;Woo, Kwang-Sung
    • Journal of the Computational Structural Engineering Institute of Korea
    • /
    • v.23 no.3
    • /
    • pp.331-340
    • /
    • 2010
  • The basic theory and application of new adaptive finite element algorithm have been proposed in this study including the adaptive hp-refinement strategy, and the effective method for constructing hp-approximation. The hp-adaptive finite element concept needs the integrals of Legendre shape function, nonuniform p-distribution, and suitable constraint of continuity in conjunction with irregular node connection. The continuity of hp-adaptive mesh is an important problem at the common boundary of element interface. To solve this problem, the constraint of continuity has been enforced at the common boundary using the connectivity mapping matrix. The effective method for constructing of the proposed algorithm has been developed by using hierarchical nature of the integrals of Legendre shape function. To verify the proposed algorithm, the problem of simple cantilever beam has been solved by the conventional h-refinement and p-refinement as well as the proposed hp-refinement. The result obtained by hp-refinement approach shows more rapid convergence rate than those by h-refinement and p-refinement schemes. It it noted that the proposed algorithm may be implemented efficiently in practice.

The Effect of HP4060 on the Brain Neurotransmitter and Hot Flushes in the Female Sprague-Dawley Rat

  • Seo, Jin-Sook;Kum, Eun-Joo;Kwon, Do-Hyeong;Lee, Hye-Young
    • Biomedical Science Letters
    • /
    • v.16 no.2
    • /
    • pp.96-104
    • /
    • 2010
  • In this study, the effects of HP4060, a pomegranate extract, on Sprague-Dawley (SD) female rats were investigated. SD rats used in the experiment were divided into 3 groups: a control group, 100 mg HP4060/kg rat powder fed group, and 25 mg HP4060/kg rat liquid fed group. After 20 days of administration, the changes of the brain neurotransmitters were measured. The data showed that the concentration of the serotonin and the norepinephrine were increased, whereas that of the epinephrine was decreased in HP4060 administered groups. In addition, the improving effect of HP4060 on depression symptom of menopause women were shown by increased immobility time of the SD rates in a separate experiment. The uterus weight of HP4060 fed groups were also shown to be increased. In order to monitor toxic effect of HP4060, glutamic-oxaloacetic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) levels were measured, and the results showed that no significant difference in GOT and GPT levels among experimental groups implying no significant toxic side effects of HP4060. According to these results, it seems clear that HP4060 may improve symptoms of hot flush and depression caused by menopause without significant level of toxic effects.

비즈니스인사이드 - 한국 HP, 세계 최고 속도 오피스젯 프로 X 시리즈 출시

  • Jo, Gap-Jun
    • 프린팅코리아
    • /
    • v.12 no.4
    • /
    • pp.88-89
    • /
    • 2013
  • 한국 HP가 지난 3월 13일 타임스퀘어 아모리스홀에서 신제품 출시회를 갖고 빠른 인쇄 속도와 경제성을 동시에 잡은 HP 오피스젯 프로 X 시리즈를 공개했다. 한국HP는 오피스젯 프로 X 시리즈를 통해 대기업 부서 및 중소기업에 효율적인 문서 출력 환경을 제공하며, 기업용 잉크젯 프린터 시장 판도에 혁신적인 변화를 주도하겠다고 밝혔다.

  • PDF

Effects of Hydrolysis pH on Distribution of Molecular Weights of Alginates of Sea Tangle Laminaria japonica (다시마 (Laminaria japonica) 알긴산의 분자량 분포에 미치는 가수분해 pH의 영향)

  • Lim, Yeong-Seon;You, Byeong-Jin
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.39 no.4
    • /
    • pp.313-317
    • /
    • 2006
  • To prepare oligouronic acids from high-molecular-weight alginates, sea tangle (Laminaria japonica) alginates were hydrolyzed at various pHs for 1 hr at 80$^{\circ}C$. The effects of hydrolysis pH (HpH) on the average molecular weight (AMW) and MW distribution ratios (DRs) in the hydrolyzed alginates were investigated. As HpH decreased, the DRs of the alginates with MW>500 kDa and MW=300-500 kDa decreased exponentially, while it increased exponentially for MW<50 kDa. For MW=100-300 kDa, DR increased exponentially as HpH fell from 5.0 to 3.5, and then decreased exponentially. Similarly, for MW=50-100 kDa, DR increased exponentially as HpH increased to 1.0 from 5.0, and then decreased exponentially. As HpH decreased, the MW cutoff size and AMW of alginates fraction with the highest DR were decreased. For HpH 4.5 and 5.0, the MW cutoff size with the highest DRs was MW=300-500 kDa; the DRs were 28.9 and 32.6%, respectively; and the AMW of both was about 400 kDa, for HpH 3.5 and 4.0, the cutoff size was MW=100-300 kDa; the DRs were about 28%: and the AMWs were both about 200 kDa. For HpH 3.0, the cutoff size was MW=50-100; the DR was 29.0%; and the AMW was 73 kDa. For HpH values below 2.0, the MW cutoff size with the highest DRs was MW<50 kDa, and all of the AMWs were below 28 kDa.

Influence of Dietary Protein Source and Level on Lead Accumulation in Rat (단백질 급원과 수준을 달리한 식이가 흰쥐의 납축적에 미치는 영향)

  • 김옥경
    • Journal of Nutrition and Health
    • /
    • v.19 no.3
    • /
    • pp.211-223
    • /
    • 1986
  • In this experiment forty-eight Sprague Dawley male rats were chosen and used in order to measure the growth rates and to see the effects of lead acumulation in their organs resulting from variously controlled lead protein diet. Protein sources were casein and isolated soyprotein (ISP), and each source was divided into three groups : 7% low protein [LP], 20% standard protein (SP) and 40% high protein (HP) groups. The six experimental groups were given lead acetate(25 mg/kg B.W.) and six control groups were given sodium chloride by oral administration 6 times a week for weeks. The results from this experiment were summeraized as following ; 1) Food consumption, weight gain, organ weight and food efficiency ; Lead acetate administration with protein source had no effects on food consumption, weight gain and organ weight . By their different levels of protein, food consumption of LP group was less the that of SP and HP groups after 3 weeks, weight gain of LP group was less than that of SP and HO groups after 1 weeks. The organ weight in LP group was significantly lower than SP and HP groups except teeth and adrenal s. Effect of lead acetate administration on food efficiency have significantly lower in LP-ISP diet and HP -casein diet than other groups only first week. By their different levels LP group showed significantly lower than SP group until 3 weeks. 2) Hematopoietic effect ; The hematopoieteic effect was not influencec by lead acdtate administration and protein source. But the LP group showed a significantly lowe hematopoietic effect than the SP, HP, groups. 3) Accumulation of lead in the liver, kidney, teeth by protein source showed no significantly differences. Accumulation of lead in blood, heart of LP group, spleen of LP and HP groups. femur of SP and HP groups fed with casein diet groups were significantly higher than fed with ISP diet groups. By their different levels of group showed generally higher than SP and HP groups. But accumulation of lead in teeth of HP group was high also.

Evaluation of HP300 Soybean Protein in Starter pig Diets

  • Zhu, Xiaoping;Li, Defa;Qiao, Shiyan;Xiao, Changting;Qiao, Qingyan;Ji, Cheng
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.11 no.2
    • /
    • pp.201-207
    • /
    • 1998
  • One growth trial and one digestibility trial were conducted to evaluate the nutritional value of HP300, a commercially processed soybean meal product for weanling pigs. Dried whey, fish meal and/or full fat extruded soybeans (FFES) as well as portions of soybean meal (SBM) were replaced with HP300 in weanling pig diets. The objectives were to investigate the effects of HP300 on growth performance, digestibility, ileal amino acid digestibility and blood amino acid concentration in weanling pigs. One hundred and twenty crossbred $(Duroc{\times}Beijing\;Black{\times}Landrace)$ pigs weaned at 28 days of age were used in the growth trial. The pigs were randomly allocated to five treatments, with three pens per treatment and eight pigs per pen. The trial duration was 28 days. The control (CTRL) diet contained no HP300; in treatments 2, 3 and 4, dried whey and fish meal were replaced by 3.0%, 7.5% and 10.5% HP300; in treatment 5, full fat extruded soybeans were replaced by 10.5% HP300 plus soybean oil to attain the same metabolic energy content as FFES. Five T-cannulated barrows were used in a digestibility trial with a $5{\times}5$ Latin square design to determine nitrogen retention and amino acid ileal digestibility of HP300 used alone or mixed with other ingredients. The results indicated that replacement of dried whey, fish meal, full fat extruded soybeans and a part of the soybean meal with HP300 in piglet diets improved average daily gain and feed conversion ratio (p < 0.05). There was a trend toward improved DM, crude protein and amino acid ileal digestibilities and improved protein and amino acid ileal digestibilities and improved protein net availability with the use of HP300 in swine diets.

Preparing of Carbon Fiber Composites Using by Vacuum Bag Hot-press Molding Process and Comparison with the other Molding Processes (진공백 핫 프레스 성형공정을 이용한 탄소섬유 복합재료의 제조와 공정비교)

  • Heo, Won-Wook;Jeon, Gil Woo;An, Seung Kook
    • Composites Research
    • /
    • v.33 no.2
    • /
    • pp.76-80
    • /
    • 2020
  • In this study, vacuum bag hot-press (V-HP) process can be used as an out-of-autoclave (OOA) process by improving the inefficient process of the autoclave forming method with excellent physical properties and surface quality. A carbon fiber composite was molded via V-HP process and analyzed the physical properties and microstructures between composites manufactured by autoclave (AC) process and hot-press process (HP). The tensile strength of the composite materials using the V-HP process was 320.6 MPa and the AC process samples found to be substantially close to the tensile strength of 335.3 MPa. As a result of confirming the surface quality of the composite material using SEM, it was confirmed that in the V-HP process, the removal state of pores due to volatile solvent in the resin was slightly lower than that of the AC process, but it had a considerably superior surface compared to the HP process.