• 대한간호학회지
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• 제35권3호
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• pp.546-554
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• 2005

Purpose: This study was a systematic review and meta-analysis of the effects of exercise programs in patients with type II diabetes mellitus. Method: Two investigators systematically searched and reviewed English articles from PUBMED from 1988 to 2004, selecting randomized controlled trials on structured exercise programs for DM patients. Out of 87 studies identified, a meta analysis was done for eleven studies which satisfied inclusion criteria and focused on glycemic indices, lipid indices, and cardiac function indices. Results: The means and standard deviations were compared for experimental groups that received exercise-only or exercise and diet programs and control groups that received no intervention or only diet education. The groups were considered homogeneous as the p value of the Q score in each variable group was over 0.05. The experimental groups demonstrated a moderate positive effect on HbA,c and $VO_{2max}$ (d=0.55 & 0.5), and a small positive effect on fasting blood glucose and cholesterol (d=0.38 & 0.27) compared to the control groups. HDL and LDL cholesterol levels, however, showed a very low positive effect (d=0.11 & 0.12) in the experimental groups. Aerobic exercise was more beneficial than resistance exercise on $HbA_1c$ (d=0.59 vs 0.28) in the groups. Conclusions: Regular exercise has a positive effect on $HbA_1c$, fasting blood glucose, total cholesterol, HDL cholesterol, LDL cholesterol, and $VO_{2max}$ in Type 2 diabetic patients.

• Earthquakes and Structures
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• 제14권4호
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• pp.313-322
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• 2018

The present study is dedicated to investigate the SH body-as well as Love-waves propagation effects in porous media with uncertain porosity and permeability. A unified formulation of the governing equations for one-dimensional (1-D) wave propagation in anisotropic porous layered media is presented deterministically. The uncertainties around the above two cited parameters are taken into account by random fields with the help of Monte Carlo Simulations (MCS). Random samples of the porosity and the permeability are generated according to the normal and lognormal distribution functions, respectively, with a mean value and a coefficient of variation for each one of the two parameters. After performing several thousands of samples, the mathematical expectation (mean) of the solution of the wave propagation equations in terms of amplification functions for SH waves and in terms of dispersion equation for Love-waves are obtained. The limits of the Love wave velocity in a porous soil layer overlaying a homogeneous half-space are obtained where it is found that random variations of porosity change the zeros of the wave equation. Also, the increase of uncertainties in the porosity (high coefficient of variation) decreases the mean amplification function amplitudes and shifts the fundamental frequencies. However, no effects are observed on both Love wave dispersion and amplification function for random variations of permeability. Lastly, the present approach is applied to a case study in the Adapazari town basin so that to estimate ground motion accelerations lacked in the fast-growing during the main shock of the damaging 1999 Kocaeli earthquake.

• 응용통계연구
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• 제21권5호
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• pp.813-823
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• 2008

비동질적 포아송과정(NHPP) 모형은 신뢰성 공학에서 소프트웨어 내에 남아있는 결함발견현상을 설명하는데 자주 사용된다. 이때 결함발견율은 연속적이며 단조함수를 가정하였으나 현실적으로 소프트웨어 시험환경, 전략 및 자원할당 등으로 인해 결함발견율이 변하는 경우가 있다. 본 논문은 결함발견율이 변화하는 변화점 문제를 고려한 소프트웨어 신뢰도 성장모형(SRGM)을 고려하여 모수를 추정하는데 목적이 있다. 이를 위해 자료를 모의 생성한 후 평균값 함수의 각 모수를 최우추정법과 최소제곱법을 이용하여 추정하며, 결함발견구간이 일정하게 증가하는 경우와 일정하게 증가하지 않는 경우를 각각 고려한다. 이때 각 모수의 적합도 비교 평가를 통하여 변화점을 고려한 SRGM에서의 최적 추정법을 수치적 방법으로 판단한다.

• 천문학회지
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• 제48권1호
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• pp.83-92
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• 2015

Recent large scale surveys such as Sloan Digital Sky Survey have produced homogeneous samples of multiple-image gravitationally lensed quasars with well-defined selection effects. Statistical analysis on these can yield independent constraints on cosmological parameters. Here we use the image separation statistics of lensed quasars from Sloan Digital Sky Survey Quasar Lens Search (SQLS) to derive constraints on cosmological parameters. Our analysis does not require knowledge of the magnification bias, which can only be estimated from the detailed knowledge on the quasar luminosity function at all redshifts, and includes the consideration for the bias against small image separation quasars due to selection against faint lens galaxy in the follow-up observations for confirmation. We first use the mean image separation of the lensed quasars as a function of redshift to find that cosmological models with extreme curvature are inconsistent with observed lensed quasars. We then apply the maximum likelihood test to the statistical sample of 16 lensed quasars that have both measured redshift and magnitude of lens galaxy. The likelihood incorporates the probability that the observed image separation is realized given the luminosity of the lens galaxy in the same manner as Im et al. (1997). We find that the 95% confidence range for the cosmological constant (i.e., the vacuum energy density) is $0.72{\leq}{\Omega}_{\Lambda}{\leq}1.0$ for a flat universe. We also find that the equation of state parameter can be consistent with -1 as long as the matter density ${\Omega}_m{\leq}0.4$ (95% confidence range). We conclude that the image separation statistics incorporating the brightness of lens galaxies can provide robust constraints on the cosmological parameters.

• 소음진동
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• 제6권2호
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• pp.163-177
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• 1996

An investigation on thermohydraulic stability of flow oscillations in the CANada Deuterium Uranium-600(CANDU-6) heat transport system has been conducted. Flow oscillations in reactor coolant loops, comprising two heat sources and two heat sinks in series, are possibly caused by the response of the pressure to extraction of fluid in two-phase region. This response consists of two contributions, one arising from mass and another from enthalpy change in the two-phase region. The system computer code used in the investigation os SOPHT, which is capable of simulating steady states as well as transients with varying boundary conditions. The model was derived by linearizing and solving one-dimensional, homogeneous single- and two-phase flow conservation equations. The mass, energy and momentum equations with boundary conditions are set up throughout the system in matrix form based on a node-link structure. Loop stability was studied under full power conditions with interconnecting the two compressible two phase regions in the figure-of-eight circuit. The dominant function of the interconnecting pipe is the transfer of mass between the two-phase regions. Parametric survey of loop stability characteristics, i. e., damping ratio and period, has been made as a function of geometrical parameters of the interconnection line such as diameter, length, height and orifice flow coefficient. The stability characteristics with interconnection line has been clarified to provide a simple criterion to be used as a guide in scaling of the pipe.

• Korea-Australia Rheology Journal
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• 제13권1호
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• pp.29-35
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• 2001

The development of filament stretching extensional rheometers over the past decade has enabled the systematic measurement of the transient extensional stress growth in dilute and semi-dilute polymer solutions. The strain-hardening in the extensional viscosity of dilute solutions overwhelms the perturbative effects of capillarity, inertia & gravity and the kinematics of the extensional deformation become increasingly homogeneous at large strains. This permits the development of a robust open-loop control algorithm for rapidly realizing a deformation with constant stretch history that is desired for extensional rheometry. For entangled fluids such as concentrated solutions and melts the situation is less well defined since the material functions are governed by the molecular weight between entanglements, and the fluids therefore show much less pronounced strain-hardening in transient elongation. We use experiments with semi-dilute/entangled and concentrated/entangled monodisperse polystyrene solutions coupled with time-dependent numerical computations using nonlinear viscoelastic constitutive equations such as the Giesekus model in order to show that an open-loop control strategy is still viable for such fluids. Multiple iterations using a successive substitution may be necessary, however, in order to obtain the true transient extensional viscosity material function. At large strains and high extension rates the extension of fluid filaments in both dilute and concentrated polymer solutions is limited by the onset of purely elastic instabilities which result in necking or peeling of the elongating column. The mode of instability is demonstrated to be a sensitive function of the magnitude of the strain-hardening in the fluid sample. In entangled solutions of linear polymers the observed transition from necking instability to peeling instability observed at high strain rates (of order of the reciprocal of the Rouse time for the fluid) is directly connected to the cross-over from a reptative mechanism of tube orientation to one of chain extension.

• 한국공간정보시스템학회 논문지
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• 제11권4호
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• pp.39-46
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• 2009

일반적으로 휴리스틱을 이용한 알고리즘에서는 탐색 비용이 증가하는 문제가 발생할 수 있다. 휴리스틱에 의해 결정된 추정 경로에 실제 경로가 존재하지 않을 경우, 휴리스틱 가중치 값이 비슷한 2 가지 이상의 경로가 존재할 경우 탐색 비용이 증가한다. 이 논문에서는 탐색 비용 증가 문제점을 해결하기 위해 추상 그래프를 제안한다. 추상 그래프는 실제 도로를 단순화한 그래프로서, 전체 지도를 고정된 크기의 그리드 셀로 나누고, 셀과 도로 정보를 기반으로 생성된다. 경로 탐색은 추상 그래프 탐색, 실제 도로 네트워크 탐색 순으로 2단계로 수행된다. 106,254개의 간선으로 이루어진 실제 도로 네트워크 데이터에 대해서 성능 평가 실험을 수행한 결과와 탐색 비용 측면에서 그리드 셀 크기에 따라 그리드 기반 A* 알고리즘에 비해 최소 3%에서 최대 35% 좋은 성능을 보였다. 반면에 유효 셀을 제외한 영역에 대한 탐색이 이루어지지 않기 때문에, 생성된 경로의 이동 비용은 1.5~6.6% 증가하였다.

• Bulletin of the Korean Chemical Society
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• 제31권6호
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• pp.1479-1484
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• 2010

Photosynthesis uses light energy to drive the oxidation of water at an oxygen-evolving catalytic site within photosystem II (PSII). Chlorophyll binding by the photosystem II subunit S protein, PsbS, was found to be necessary for energy-dependent quenching (qE), the major energy-dependent component of non-photochemical quenching (NPQ) in Arabidopsis thaliana. It is proposed that PsbS acts as a trigger of the conformational change that leads to the establishment of nonphotochemical quenching. However, the exact structure and function of PsbS in PSII are still unknown. Here, we clone and express the recombinant PsbS gene from Arabidopsis thaliana in E. coli and purify the resulting homogeneous protein. We used various biochemical and biophysical techniques to elucidate PsbS structure and function, including circular dichroism (CD), fluorescence, and DSC. The protein shows optimal stability at $4^{\circ}C$ and pH 7.5. The CD spectra of PsbS show that the conformational changes of the protein were strongly dependent on pH conditions. The CD curve for PsbS at pH 10.5 curve had the deepest negative peak and the peak of PsbS at pH 4.5 was the least negative. The fluorescence emission spectrum of the purified PsbS protein was also measured, and the ${\lambda}_{max}$ was found to be at 328 nm. PsbS revealed some structural changes under varying temperature and oxygen gas condition.

• 디지털융복합연구
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• 제11권9호
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• pp.159-166
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• 2013

본 연구에서는 소프트웨어 제품을 개발하여 테스팅을 거친 후 사용자에게 인도하는 시기를 결정하는 방출문제에 대하여 연구 하였다. 소프트웨어의 결함을 제거하거나 수정 작업과정에서 유한고장수를 가진 비동질적인 포아송과정에 기초하였다. 수명강도는 다양한 형상모수와 척도모수에 이용 할 수 있기 때문에 신뢰성 분야에서 많이 사용되는 비선형 특성을 가진 반-로지스틱 분포 모형을 이용한 방출시기에 관한 문제를 제시하였다. 소프트웨어 요구 신뢰도를 만족시키고 소프트웨어 개발 및 유지 총비용을 최소화 시키는 최적 소프트웨어 방출 정책에 대하여 논의 되었다. 본 논문의 수치적인 예에서는 고장 시간 자료를 적용하였으며 모수추정 방법은 최우추정법을 이용하고 최적 방출시기를 추정하였다. 따라서 소프트웨어 방출시기를 사전 정보로 활용하면 잠재적 보안피해액을 줄 일 수 있다고 판단된다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2009년도 추계학술대회
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• pp.245-248
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• 2009

최근 단말기 기반의 경로 탐색에서도 동적인 정보를 반영하기 위한 연구가 진행되고 있다. 그러나 제시하는 대부분의 알고리즘은 $A{\ast}$알고리즘을 기반으로 한다. 휴리스틱을 이용한 알고리즘에서는 다음과 같은 탐색 비용이 증가하는 문제가 발생할 수 있다. 휴리스틱에 의해 결정된 추정 경로에 실제 경로가 존재하지 않을 경우, 휴리스틱 가중치 값이 비슷한 2가지 이상의 경로가 존재할 경우 탐색 비용이 증가한다. 이 논문에서는 생성 방법이 다른 추상 그래프의 성능을 평가 하였다. 추상 그래프는 실제 도로 네트워크를 단순화한 그래프로, 휴리스틱의 의존성과 탐색 비용을 줄이기 위해 제안된 방법이다. 추상 그래프는 생성 방법에 따라 동일 특성 노드 합병을 통한 추상 그래프($AG^H$)와 연결 노드 합병을 통한 추상 그래프($AG^C$)로 구별된다. 성능 실험 결과 생성 비용 측면에서 $AG^C$가 좋은 성능을 보였지만, 탐색 성능 측면에서는 $AG^H$가 좋은 성능을 보였다.