• Journal of Pharmaceutical Investigation
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• 제19권3호
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• pp.117-121
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• 1989

A metal complex, copper (II) L-proline was chemically bound to ethylene glycol dimethacrylate and divinylbenzene crosslinked chloromethylated polystyrene and they were used as chiral chelate resin matrix for column chromatography to resolve enantiomers of DL-amino acids. The L-enantiomers eluted first and the degree of resolution on the polymer crosslinked with ethylene glycol dimethacrylate was superior to the polymer crosslinked with divinylbenzene.

• BMB Reports
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• 제33권2호
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• pp.148-154
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• 2000

The glycation process plays an important role in accelerated atherosclerosis in diabetes, and the uptake of atherogenic lipoproteins by macrophage in the intima of the vessel wall leads to foam cell formation, an early sign of atherosclerosis. Besides the lipolytic action on the plasma triglyceride component, lipoprotein lipase (LPL) has been reported to enhance the cholesterol uptake by arterial wall cells. In this study, some properties of LPL-mediated low-density lipoprotein (LDL) uptake and the effect of LDL glycation were investigated in RAW 264.7 cell, a murine macrophage cell line. In the presence of LPL, $^{125}I$-LDL binding to RAW 264.7 cells was increased in a dose-dependent manner. At concentrations greater than $20\;{\mu}g/ml$ of LPL, LPL-mediated LDL binding was increased about 17-fold, achieving saturation. Without LPL, both very low-density lipoprotein (VLDL) and high-density lipoprotein (HDL) were ineffective in blocking the binding of $^{125}I$-LDL to Cells. However, LPL-enhanced LDL binding was inhibited about 50% by the presence of VLDL, while no significant effect was observed with HDL. Heat inactivation of LPL caused a 30% decrease of LDL binding. In the presence of LPL, the cells took up 40% of cell-bound native LDL. No significant difference was observed in cell binding between native and glycated LDL. However, the uptake of glycated LDL was significantly greater than that of native LDL, reaching to 70% of the total cell bound glycated LDL. These results indicate that LPL can cause the significant enhancement of LDL uptake by RAW 264.7 cells and the enhanced uptake of glycated LDL in the presence of LPL might play an important role in the accelerated atherogenesis in diabetic patients.

• 한국식품영양과학회지
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• 제13권4호
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• pp.459-468
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• 1984

The currently accepted model of membrane structure proposes a dynamic, asymmetric lipid matrix of phospholipids and cholesterol with globular proteins embedded across the membrane to various degrees. Most phospholipids are in the bilayer arrangement and also closely associated with integral membrane proteins or loosely associated with peripheral proteins. Biological functions of membrane, such as membrane-bound enzyme functions and transport systems, are influenced by the membrane physical properties, which are determined by fatty acid composition of phospholipids, polar head group composition and membrane cholesterol content. Polar and non-polar region of the phospholipid molecule can interact, with changes in the conformation of a membrane-associated protein altering either its catalytic activity or the protein's interaction with other membrane proteins. Mammalian dietary studies attempted to change the lipid composition of a few cell membranes have shown comparisons, using essential fatty acid-deficient diets. In recent years, Clandinin and a few other workers have pioneered the study proving the influence of dietary fat fed in a nutritionally complete diet on composition of phospholipid classes of cell membrane. Modulation caused by diet fat was rapid and reversible in phospholipid fatty acyl composition of membranes of cardiac mitochondria, liver cell, brain synaptosome and lymphocytes. These changes were at the same time, accompanied by variety of membrane associated functions controlled by membrane-bound enzymes, tranporter and receptor proteins. The findings suggest the basic concept of the necessity of dietary fatty acid balance if consistency of optimal membrane structural lipid composition is to be maintained, as well as the overall inadequacy of describing the nutritional-biochemical quality of a dietary fat solely by its content of linoleic acid. Furthermore, they give light on the possible application to clinical and preventive medicine.

• 한국의류산업학회지
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• 제13권3호
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• pp.418-424
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• 2011

The purpose of this study was to reveal the effects of the seam type on the fabric drape to provide the basic knowledge for proper seam type according to the design of sewing products. Seven kinds of specimens were constructed with seam (no seam, welt seam with over-edged finish, welt seam with bias bound finish, plain seam with over-edged finish, plain seam with bias bound finish, french seam, and flat fell seam) in wrap direction of the fabric. Using a drape measurement system involving two 18 cm diameter supporting disks, and a digital camera, the images of draped specimens were captured and processed. Drape behavior was evaluated in terms of drape coefficient, node number, and drape profile. Significant differences were found in drape coefficient by the seam types. The specimens with french seam and flat fell seam showed higher drape coefficients compared to those with welt seam and plain seam. Node numbers in the drape profiles showed positive correlation with the weight of the specimens, however, no significant differences were observed in node numbers by the seam types. Significant differences were found in the length of the seamed part by the seam types. The specimens with french seam and flat fell seam showed longer length of the seamed part compared to those with welt seam and plain seam. The ratio of the maximum length in the seam direction to the maximum length perpendicular to the seam direction showed significant differences by the seam types.

• 한국컴퓨터정보학회논문지
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• 제17권6호
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• pp.153-161
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• 2012

본 연구는 웹 환경에서 어플리케이션 복잡도의 빈도분포를 근거로 한계값의 적정성을 분석하기 위한 실험을 하였으며 두 가지 가정을 기준으로 작업하였다. 즉, 절차적 프로그래밍에서 McCabe의 상한값 10과 자바 프로그래밍에서의 Lopez의 상한값 5에 대하여 웹 프로그래밍 구문에 이들 설정값의 적용이 가능한가?에 대한 실험으로 10 웹 사이트 프로젝트를 수집하였고 4,000여개의 ASP파일 표본이 측정되었다. 웹 어플리케이션에 대한 복잡도 빈도분포를 파악한 결과 통합된 웹 어플리케이션의 90% 이상이 복잡도 50이하의 값을 가짐으로써 한계값 50이 제안되었다. 서버, 클라이언트, HTML이 통합된 웹 어플리케이션의 구조상 HTML의 복잡도가 35~40의 값을 가지게 되는데 이는 HTML이 주로 홈 페이지나 사이트 맵을 구성하는 메뉴 형태로 되어 있어 높은 복잡도의 적합성이 설명되었다. 향후 웹 어플리케이션의 구조상 복잡도와 관련된 숨어 있는 속성은 없는지 관련성을 찾아보는 노력이 필요하다.

• 대한가정학회지
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• 제24권2호
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• pp.123-137
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• 1986

The present study was designed to answer the following questions : The first overall question had to do with the relationship between sex-role identity and self-esteem-more specifically, is androgyny or masculinity more importamt in explaining the variation in self-esteem? The second overall question had to do with the degree to which the relationship between sex-role identity and self-esteem is a universal or a culturally specific phenomeon-more specifically, is the relationship between sex-role identity and self-esteem the same in Korean and American cultures? The Bem Sex Role Inventory and the Coopersmith Self Esteem Inventory were administered to 208 American college students and 207 Korean college students, respectively, in introductory sociology classes. The BSRI and SEI are standardized for American subjects and written in English. Prior to administering these instruments to Korean subjects, they were translated ito the Korean Language. In order to fully explore the data, qualitative as well as quantitative measurement of the BSRI were used, and both factorial and regression analyses were performed in this study. The most important cross-cultural differences found in the present study are directly related to the two research questions. In the U.S. sample, masculine attributes were found to be more important in explaining self-esteem. On the other hand, androgynous attributes were positively related to self-esteem in the Korean sample. These findings also provide the answer to the second question. That is, different cross-cultural patterns of relationship were found between sexrole identity and self-esteem, providing some support for a culture-bound relationship. These cross-cultural differences were discussed in terms of both confucian values held by Koreans and Bakan's suggestion of a positive relationship between agentic characteristics and modernization.

• 대한가정학회지
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• 제30권1호
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• pp.99-113
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• 1992

This study was performed to investigate the effect of dietary protein and calcium levels on cadmium detoxication in rats. Seventy male Sprague-Dawley rats weighing 208 $\pm$ 19 g were blocked into 10 groups of 7 animals according to body weight. Five groups were fed 15% protein-0.6% calcium diet with 100ppm cadmium in drinking water for first 15days and the other 5groups fed same diet without cadmium in drinking water for same period and served as controls. After this 15-day intoxication period, each one of cadmium intoxication and control groups were fed each of 4 kinds of detoxifying diets different with protein(40%, 15%) and calcium(1.3%, 0.6%) levels without cadmimum in drinking water for following 15 days of detoxifying period. Results were summarized as follows: 1) Food intake, body weight gain, F.E.R. and weights of liver, kidney and femur were increased by detoxifying diets and high protein diet was most effective in weight gains of liver and kidney. 2) When cadmium and metallothionein contents of initial intoxication group and those of all detoxication groups were compared, cadmium and metallothionein contents in the liver were not changed, but those in kidney increased, and those in intestine decreased markedly. 3) Only dietary protein level affected cadmium and metallothionein distribution among organs, and cadmium contents of whole blood, liver, kidney and femur were lower in high protein diet, but metallothionein contents in liver and kidney were higher in high protein diet. 4) Gel filtration chromatogram showed that most of cadmium in the cytosol was bound to metallothionein fractions in high protein-high calcium group. Results obtained indicated that high protein diet was effective in cadmium detoxication by increasing the induction of metallothionein synthesis. But high calcium diet did not play a role in cadmium detoxication.

• 한국사회복지학
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• 제47권
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• pp.310-333
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• 2001

The purposes of this research were 1) to investigate the characteristics of the meal service participants; 2) to evaluate the food service utilization of the elderly; 3) to identify major factors that affect food service satisfaction of the participants in Chungchongbuk-Do. For doing this, 309 subjects were selected and the survey research method was adopted. The characteristics of the meal service participants were similar to the characteristics of general elderly population in Korea. The public assistant recipients were under representative in this sample, that is, most of elderly people who participated in meal service consisted of non public assistant recipients. It meant that meal service was not provided to low-income elderly people. The health status of the elderly people was stable to be able to attend to the meal service organizations. The most important reason to use a meal service was to see their friends. It showed that meal services played an important role to provide support systems to the elderly people in community. Thus, meal services should be provided to the elderly people with social services. In order to analyze the factors influencing food service satisfaction, multiple regression analysis was employed. The results showed that physical activity, contact with friends who met in meal service program, and the number of social services were the important variables to predict meal service satisfaction in this study. These findings contributed to a better understanding of developing a meal service planning. Several improvement strategies were recommended to provide effective meal services. First, socio-economical characteristics of the elderly should be considered to provide appropriate services. Second, meal services should be provided to the elderly people with social services. Third, home delivery meal services should be available to the home-bound elderly.

• 가정과삶의질연구
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• 제15권1호
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• pp.41-52
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• 1997

This paper explored the public issue on housework analyzed the policy and the law associated housework and developed the theorical model for its political program. This idea is dependent that the policy has priority over change of the social ideology. That policy contains a campaign and a education to be aimed to share of housework in order to make responsibility of men as well as women on family and work. Also it contains economic value estimates to quantify and value the non-wage work(childcaring homemaking etc.) in order to confirm its productive activity. It would assume the lawful form as like a social security or a pension. For example the Family Rights Law Tax Law and Social Security Act have to be reflected on the value of housework and to be secured the social status of provider. After all this work was useful to improve a wage and a social status of all women. As consistent policy and operation associated housework are poor in Korea it is difficult to develop theoric l model on this theme. On the range a political proposal on housework would be bound by family policy(evaluation of housework) and women's labor policy(housework support). So the policy intend to secure a family life to improve welfare of women and to equilibrate the family and the work.

• 대한기계학회논문집A
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• 제29권5호
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• pp.689-697
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• 2005

This paper presents the reliability estimation of door hinge for home appliances, which consists of bushing and shaft. The predominant failure mechanism of bushing made of polyoxymethylene(POM) is brittle fracture due to decrease of strength caused by voids existing, and that of shaft made of acrylonitrile-butadiene-styrene(ABS) is creep due to plastic deformation caused by excessive temperature and lowering of glass transition temperature by absorbed moisture. Since the brittle fracture of bushing is overstress failure mechanism, the load-strength interference model is used to estimate the failure rate of it along with failure analysis. By the way, the creep of shaft is wearout failure mechanism, and an accelerated life test is then planned and implemented to estimate its lifetime. Through the technical review about failure mechanism, temperature and humidity are selected as accelerating variables. Assuming Weibull lifetime distribution and Eyring model, the life-stress relationship and acceleration factor, $B_{10}$ life and its lower bound with $90\%$ confidence at worst case use condition are estimated by analyzing the accelerated life test data.