• Clinical Endoscopy
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• v.55 no.6
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• pp.726-735
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• 2022

Inflammatory bowel disease (IBD) has a global presence with rapidly increasing incidence and prevalence. Patients with IBD including those with ulcerative colitis and Crohn's disease have a higher risk of developing colorectal cancer (CRC) compared to the general population. Risk factors for CRC in patients with IBD include long disease duration, extensive colitis, primary sclerosing cholangitis, family history of CRC, stricture, and prior dysplasia. Surveillance colonoscopy for CRC in patients with IBD should be tailored to individualized risk factors and requires careful monitoring every year to every five years. The current surveillance techniques are based on several guidelines. Chromoendoscopy with targeted biopsy is being recommended increasingly, and high-definition colonoscopy is gradually replacing standard-definition colonoscopy. However, it remains unclear whether chromoendoscopy, virtual chromoendoscopy, or white-light endoscopy has better efficiency when a high-definition scope is used. With the development of new endoscopic instruments and techniques, the paradigm of surveillance strategy has gradually changed. In this review, we discuss cutting-edge surveillance colonoscopy in patients with IBD including a review of literature.

• Child Health Nursing Research
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• v.30 no.1
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• pp.67-74
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• 2024

Purpose: This study aimed to identify the general characteristics and health behaviors of students with non-therapeutic substance use. Methods: This secondary data analysis used data from the 17th Korea Youth Risk Behavior Web-based Survey (2021). Analyses of the 54,848 adolescents used descriptive statisics, the Rao-Scott χ² test, and logistic regression. Results: The risk factors for substance use among students were anxiety, loneliness, living separately from family, suicidal ideation, e-cigarette use, and high stress. Conclusion: The findings help identify the risk factors for non-therapeutic drug use among adolescents. Since South Korea does not have a drug prevention program for its adolescent population, an educational plan based on these findings could help prevent adolescent substance abuse.

• Journal of Forest and Environmental Science
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• v.40 no.1
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• pp.24-34
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• 2024

Fire, being primarily a natural phenomenon, is impossible to control, although it is feasible to map the forest fire risk zone, minimizing the frequency of fires. The spread of a fire starting in any stand in a forest can be predicted, given the burning conditions. The natural cover of the land and the safety of the population may be threatened by the spread of forest fires; thus, the prevention of fire damage requires early discovery. Satellite data and geographic information system (GIS) can be used effectively to combine different forest-fire-causing factors for mapping the forest fire risk zone. This study mainly focuses on mapping forest fire risk in the Madikhola watershed. The primary causes of forest fires appear to be human negligence, uncontrolled fire in nearby forests and agricultural regions, and fire for pastoral purposes which were used to evaluate and assign risk values to the mapping process. The majority of fires, according to MODIS events, occurred from December to April, with March recording the highest occurrences. The Risk Zonation Map, which was prepared using LULC, Forest Type, Slope, Aspect, Elevation, Road Proximity, and Proximity to Water Bodies, showed that a High Fire Risk Zone comprised 29% of the Total Watershed Area, followed by a Moderate Risk Zone, covering 37% of the total area. The derived map products are helpful to local forest managers to minimize fire risks within the forests and take proper responses when fires break out. This study further recommends including the fuel factor and other fire-contributing factors to derive a higher resolution of the fire risk map.

• Korean Journal of Health Education and Promotion
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• v.3 no.1
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• pp.113-128
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• 2001

The purpose of this study is to examine the prevalence and correlates of three types of risk-taking behavior among high school students in Korea in a cross-sectional national sample. A sample of 636 male and 622 female high school students is analyzed using descriptive statistics and logistic regression. Three types of risk-taking behavior are examined: drinking alcohol, smoking, and premarital sex. The results are as follows: Forty-three percent of students in the sample have ever drunk alcohol, 32% have ever smoked, 11% have experience premarital sex. Risk-taking behavior is more prevalent among boys than among girls. Boys and girls in Seoul are much more likely to have experienced three types of risk-taking behavior. Not having two parents in the family and having lived away from immediate family increase the likelihood of some risk-taking behavior. Students who have a friend with premarital sexual experience are much more likely to have experienced premarital sex themselves. Among sexually active students, having multiple sexual partners is common and prevalence of condom use is low. Reproductive health education at school has no effect on students' sexual behavior. The prevalence of risk-taking behavior among adolescent in Korea is likely to rise in the future. Substantial proportion of adolescents are exposed to the risks of STDs and substantial proportion of adolescent girls risk premarital pregnancy. Current health education programs are inadequate in protecting students from risk-taking behavior. Students whose families do not include both parents and students who live away from their immediate families need special programs to protect them from risk-taking behavior.

• BMB Reports
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• v.36 no.6
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• pp.533-537
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• 2003

The nonsyndromic cleft lip and palate (NSCL/P) is a congenital deformity of multifactorial origin with a relatively high incidence in the oriental population. Various etiologic candidate genes have been reported with conflicting results, according to race and analysis methods. Recently, the ablation of the TGF-${\beta}3$ gene function induced cleft palates in experimental animals. Also, polymorphisms in the TGF-${\beta}3$ gene have been studied in different races; however, they have not been studied in Koreans. A novel A $\rightarrow$ G single nucleotide polymorphism (defined by the endonuclease SfaN1) was identified in intron 5 of TGF-${\beta}3$ (IVS5+104 A > G). It resulted in different genotypes, AA, AG, and GG. The objective of this study was to investigate the relationship between the SfaN1 polymorphism in TGF-${\beta}3$ and the risk of NSCL/P in the Korean population. The population of this study consisted of 28 NSCL/P patients and 41 healthy controls. The distribution of the SfaN1 genotypes was different between the cases and controls. The frequency of the G allele was significantly associated with the increased risk of NSCL/P [odds ratio (OR) = 15.92, 95% confidence interval (CI) = 6.3-41.0]. The risk for the disease increased as the G allele numbers increased (GA genotype: OR = 2.11, 95% CI = 0.38-11.68; GG genotype: OR = 110.2, 95% CI = 10.67 - 2783.29) in NSCL/P. A stratified study in patients revealed that the SfaN1 site IVS5+104A > G substitution was strongly associated with an increased risk of NSCL/P in males (p < 0.001), but not in females. In conclusion, the polymorphism of the SfaN1 site in TGF-${\beta}3$ was significantly different between the NSCL/P patients and the control. This may be a good screening marker for NSCL/P patients among Koreans.

• Korean Journal of Health Education and Promotion
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• v.19 no.1
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• pp.17-30
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• 2002

BACKGROUND: Back pain is a popular disease in general population as well as in workers. School students handle heavy bag and keep awkward postures during class long time. However, the prevalence of back pain among students and the risk factors associated with back pain are not well known. METHODS: In this study, we assess the frequency of risk factors for back pain among 2,717 high school students. From April 2001 to May 2001, using a self-reported questionnaire, we collected data on occurrence of back pain and potential risk factors for back pain. RESULTS: Fifteen percent of high school students reported having daily back pain for a week or more during the past 12 months. Female students had a higher prevalence of back pain than males(OR=2.22, 95% CI 1.69-2.91). Using a multiple logistic regression model, we found six factors associated with back pain for females; alcohol(OR=1.75, 95% CI 1.26-2.45), depression(OR=1.75, 95% CI 1.84-2.28), poor physical health(OR=2.57, 95% CI 1.84-8.58), obesity(OR=0.29, 95% CI 0.12-0.68), exercise(OR=l.50, 95% CI=1.07-2.16), and good performance(OR=l.50, 95% CI 1.05-2.18). Only alcohol, however, associated with back pain for males(OR=1.70, 95% CI 1.05-2.77) CONCLUSIONS: High school students had a relatively high prevalence of back pain. Students with alcohol consumption had the higher risk for back pain.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.9
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• pp.4725-4732
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• 2012

Aim: The incidence of stomach cancer in Mizoram is highest in India. We have conducted a population based matched case-control study to identify environmental and genetic risk factors in this geographical area. Methods: A total of 102 histologically confirmed stomach cancer cases and 204 matched healthy population controls were recruited. GSTM1 and GSTT1 genotypes were determined by PCR and H. pylori infections were determined by ELISA. Results: Tobacco-smoking was found to be an important risk factor for high incidence of stomach cancer in Mizoram. Meiziol (local cigarette) smoking was a more important risk factor than other tobacco related habits. Cigarette, tuibur (tobacco smoke infused water) and betel nut consumption synergistically increased the risk of stomach cancer. Polymorphisms of GSTM1 and GSTT1 genes were not found to be directly associated with stomach cancer in Mizoram. However, they appeared to be effect modifiers. Persons habituated with tobacco smoking and/or tuibur habit had increased risk of stomach cancer if they carried the GSTM1 null genotype and GSTT1 non-null genotype. Conclusion: Tobacco smoking, especially meiziol is the important risk factor for stomach cancer in Mizoram. GSTM1 and GSTT1 genes modify the effect of tobacco habits. This study is a first step in understanding the epidemiology of stomach cancer in Mizoram, India.

• Korean Journal of Biological Psychiatry
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• v.13 no.2
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• pp.103-109
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• 2006

Objective : Associations of vascular risk/disease or apolipoprotein E ${\varepsilon}4$(APOE4) with geriatric depression has been unclear at a population level. This study aimed to evaluate whether there would be interactions of vascular risk/disease and APOE4 on depression in a Korean elderly population. Methods : 732 community residents aged 65 or over were assessed for depression(GMS), information on vascular risk/disease(reported stroke, transient ishemic attack, heart disease, hypertension, diabetes, smoking), examinations for vascular risk/disease(blood pressure, blood tests for glucose and lipid profiles, body size), APOE genotypes, demographic characteristics(age, gender, education), physical health, and cognitive function(MMSE). Results : Previous stroke and lower level of high density lipoprotein(HDL) cholesterol were significantly associated with geriatric depression independent of demographic characteristics, physical illnesses, and cognitive function. These associations were statistically significant only in those with APOE4, although the interaction terms didn't reach to statistical significance. Conclusion : Associations between vascular risk/disease and geriatric depression might be more prominent in those with APOE4. However further research would be needed to clarify this issue.

• Journal of Korean Academy of Nursing
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• v.53 no.2
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• pp.167-176
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• 2023

Purpose: Despite the high prevalence of visual impairment caused by diabetic retinopathy and nutritional problems among older adults with diabetes, evidence regarding factors related to nutritional risk in this population is limited. Therefore, this study aimed to identify the correlates of nutritional risk among older adults with diabetes, focusing on visual impairment. Methods: This study was a secondary data analysis of the 2020 National Survey of Older Koreans aged 65 years and above. The sample comprised 2,376 older adults with diabetes, and complex sample ANOVA and Rao-Scott chi-square tests were used to compare the groups according to visual impairment. Complex-sample logistic regression analyses were conducted to verify the association between visual impairment and nutritional risk. Results: Older adults with diabetes, who also have severe visual impairment, are more likely to have nutritional risk status than those without impairment after controlling for covariates (odds ratio [OR] = 2.44, 95% confidence interval [CI] 1.16~5.13). Among the covariates, depression (OR = 3.58, 95% CI 2.60~4.94), dependent activities of daily living status (OR = 2.79, 95% CI 1.60~4.86), and experience of hospitalization during the past year (OR = 2.51, 95% CI 1.57~4.03) were strongly associated with nutritional risk. Conclusion: Severe visual impairment increases the nutritional risk among older adults with diabetes. Therefore, it is essential to prevent visual impairment due to exacerbation of diabetes through appropriate management. Additionally, tailored nutritional interventions for visually impaired older adults with diabetes that consider visual characteristics are required.

• Environmental Analysis Health and Toxicology
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• v.19 no.1
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• pp.49-58
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• 2004

It is important to select a risk based priority area for environmental policy formation and decision-making. We estimated the health risks and associated damage costs from exposure to fine particles and assigned priority areas for twenty -five districts in Seoul. In order to estimate the theoretical mortality incidence of the health risk, baseline risks were estimated from mortality rates in two low level areas of fine particles, Seocho Gu and Cheju city To estimate the damage cost from the risk estimates, we investigated and estimated the willingness to pay (WTP) for specific risk reduction. We assumed two different locations as the reference area, Cheju city as Scenario I and Seocho gu as Scenario II. From the results, the five districts, Kwangjin, Chungnang, Kangbuk, Nowon, and Kangnam, ranked high in the categories of both health risk and economic risk. Damage costs were over twenty billion won in each of these districts. As there are uncertainties in these results, the parameter values such as PM$_{2.5}$ level, dose -response slope factor, baseline risk, exposure population and WTP should be continuously validated and refined.d.