• 제목/요약/키워드: high-purity

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Paclitaxel : 산업화 단계에서의 회수 및 정제 (Paclitaxel : Recovery and Purification in Commercialization Step)

  • 김진현
    • KSBB Journal
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    • 제21권1호
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    • pp.1-10
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    • 2006
  • 식물세포배양으로부터 항암제 paclitaxel의 생산을 위해 회수 및 정제는 산업적 공정에 있어서 필수적이다. 본 총설은 식물세포배양으로부터 고순도, 고수율의 paclitaxel 생산을 위한 대량 회수 및 정제 방법을 기술하고자 한다. 또한 이러한 분리 및 정제 공정은 추출, 전 처리, 정제, 제품화 단계를 총괄하여 최종 제품의 요구조건들 즉, 순도, 잔류용매, 제품형태, 불순물 함량, 엔도톡신 함량 등을 충족시킬 수 있도록 최적화되어야 한다. 이러한 관점에서 본 총설은 산업화 단계에서의 의약품 생산 및 품질관리에 상당히 유용하게 활용될 수 있을 것으로 판단된다.

Aluminum Isopropoxide의 가수분해법에 의한 고순도 $\alpha$-Al2O3의 제조 (Preparation of High Purity Alumina by Alkoxide Process)

  • 백행남;이명기;곽중협;서태수
    • 한국세라믹학회지
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    • 제26권3호
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    • pp.445-451
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    • 1989
  • Hydrolysis of aluminum isopropoxide with excess water in the presence of excess isopropyl alcohol resulted in the formation of boehmite in independence of temperature of hydrolysis and aging. Stoichiometric and substoichiometric amount of water hydrolyzed aluminum isopropoxide to pseudo-boehmite and amorphous one, respectively. $\alpha$-Al2O3 with 0.3${\mu}{\textrm}{m}$ in median size was produced by calcination of boehmite, bseudo-boehmite and amorphous boehmite at 125$0^{\circ}C$, 120$0^{\circ}C$, and 115$0^{\circ}C$ for one hour, respectively. Singnificant reduction in particle size was found during transition from $\theta$-Al2O3 to $\alpha$-Al2O3. $\alpha$-Al2O3 produced in this study was relatively uniform spherical and its purity was found to be over 99.9%.

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목질계 Biomass의 변환 이용(III) - 폭쇄처리재의 산소·알칼리법에 의한 용해용 펄프의 제조 - (Conversion of Woody Biomass for Utilization(III) - The Preparation of Dissolving Pulp by Oxygen·Alkali Method from Exploded Wood -)

  • 임부국;양재경;이종윤
    • Journal of the Korean Wood Science and Technology
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    • 제25권4호
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    • pp.68-74
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    • 1997
  • This research was studied dissolving pulp for rayon production, which is not KP, SP methods but steam explosion and oxygen alkali treatment. The variation of characterization in wood cellulose after steam explosion and oxygen alkali treatment this follows. In the oxygen alkali treatment of exploded pine wood, yield of dissolving pulp was lower than steam-exploded oak wood, and we have obtained dissolving pulp that high purity cellulose, but degree of polymerization was inclined to decrease less than 200. In the case of steam-exploded oak wood, degree of polymerization was higher than steam-exploded pine wood but purity of cellulose was lower than its.

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