• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.1
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• pp.93-99
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• 2008

In this paper, we propose new modulation schemes using the conventional CACB modulation with constant amplitude property. Also the proposed modulation schemes supports high transmission data rate by increasing the spectral efficiency. In order to obtain the high spectral efficiency, the $Q^2$PSK and CA-$Q^2$PSK are used. We explain the simplest combining modulation scheme of CACB and $Q^2$PSK (i.e., CACB-$Q^2$PSK). However, this modulation scheme cannot support the constant amplitude property. Hence the first CACB-CA-$Q^2$PSK (or CACB-CA-$Q^2$PSK I) modulation scheme is proposed for the constant amplitude property. In the modulation scheme, the redundant constant amplitude encoding (spectral efficiency decrease) is required. Therefore, the second CACB-CA-$Q^2$PSK (or CACB-CA-$Q^2$PSK II) modulation scheme is proposed retaining the constant amplitude and the spectral efficiency. Computer simulations show that the proposed CACB-CA-$Q^2$PSK II is the efficient modulation scheme.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.7A
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• pp.738-745
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• 2007

The non-linearity of HPA(high power amplifier) which is an important component in modern communications systems introduces AM/AM and AM/PM distortion so that the transmitted signal is deteriorated. And, the I/Q unbalances and phase error which are generated by non-ideal components are inevitable physical phenomena and lead to performance degradation when we implement a practical two-dimensional (2-D) modulation system. In this paper, we provide an exact and general expression involving the 2-D Gaussian Q-function for the error probabilities of arbitrary 2-D signaling with I/Q amplitude and phase unbalances in nonlinear additive white Gaussian noise (AWGN) channels by using the coordinate rotation and shifting technique.

• Clinical and Experimental Pediatrics
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• v.59 no.sup1
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• pp.10-13
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• 2016

Chromosome 11q13 deletion syndrome has been previously reported as either otodental syndrome or oculo-oto-dental syndrome. The otodental syndrome is characterized by dental abnormalities and high-frequency sensorineural hearing loss, and by ocular coloboma in some cases. The underlying genetic defect causing otodental syndrome is a hemizygous microdeletion involving the FGF3 gene on chromosome 11q13.3. Recently, a new form of severe deafness, microtia (small ear) and small teeth, without the appearance of eye abnormalities, was also reported. In this report, we describe a 1-year-old girl presenting with ptosis of the left upper eyelid, right auricular deformity, high-arched palate, delayed dentition, simian line on the right hand, microcephaly, and developmental delay. In this patient, we identified a deletion in the chromosome 11q13.2-q13.3 (2.75 Mb) region by using an array-comparative genomic hybridization analysis. The deletion in chromosome 11q13 results in a syndrome characterized by variable clinical manifestations. Some of these manifestations involve craniofacial dysmorphology and require a functional workup for hearing, ophthalmic examinations, and long-term dental care.

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.27-27
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• 2022

(-)-Epicatechin (EC), a primary form of flavan-3ol and a building block of proanthocyanidins, has health benefits as it is a potent antioxidant. So far, no quantitative trait loci (QTLs) associated with EC have yet been identified in soybean. In this study, QTLs for EC and hilum color were identified in recombinant inbred lines (RILs) derived from the varieties Jinpung and IT109098 using high-resolution single nucleotide polymorphism linkage mapping. This revealed two major QTLs for EC content, qEC06 and qEC08. qEC06 spanned the T Locus encoding flavonoid 3'-hydroxylase. qEC08, located near the I locus on Chr08, was also a major QTL for hilum color; however, allelic stacking of qEC08 and I revealed no relationship between I and EC content. RILs with IT 109098 alleles at both qEC06 and qEC08 had higher EC content than other lines. These results will enable the production of soybean varieties with high EC content via marker-assisted selection.

• The Korean Journal of Ecology
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• v.21 no.3
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• pp.283-290
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• 1998

The vegetation pattern of Mt. Odae based on the soil humidity gradient showed 3 types: (1) the forest of Pinus densiflora under the mesic or xeric conditions of the low altitudinal area, (2) the forest of Acer including A. mono, A. pseudo-sieboldianum and Tilia amurensis under the submesic or subxeric conditions and (3) the forest of Quercus including Q. mongolica of the higher elevational area and Q. variabilis of the lower elevational area under the xeric condition. Water content, organic matter and total nitrogen of soil were relatively low in Pinus densiflora and Quercus variabilis communities while they were relatively high in Betula platyphylla var. japonica and Quercus mongolica communities. According to the result of cluster analysis based on similarity indices of the communities, the proposed successional sere in the forest vegetation of Mt. Odae was as follows. P. densiflora community $\longrightarrow$ P. densiflore + Q. mongolica community $\longrightarrow$ Q. mongolica + A. pseudo-sieboldianum community. P. densiflora community $\longrightarrow$ P. densiflora + Q. variabilis community $\longrightarrow$ Q. variabilis community $\longrightarrow$ Q. mongolica + Q. variabilis community $\longrightarrow$ Q. mongolica + A. pseudo-sieboldianum community.

• Food Science of Animal Resources
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• v.38 no.1
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• pp.99-109
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• 2018

In this study, we examined the inhibitory effect of L. plantarum Q180 on adipocyte differentiation in 3T3-L1 and reduction of adipocyte size in mice fed high-fat diet. L. plantarum Q180 inhibited the adipocyte differentiation of 3T3-L1 cells ($18.47{\pm}0.32%$) at a concentration of $400{\mu}g/mL$ ($10^8CFU/g$). As a result of western blot analysis, the expression of $C/EBP{\alpha}$ and $PPAR{\gamma}$ in 3T3-L1 adipocyte treated with $400{\mu}g/mL$ of L. plantarum Q180 decreased 35.16% and 40.07%, respectively, compared with the control. To examine the effects, mice were fed three different diets as follows: ND (n=6) was fed ND and orally administered saline solution; HFD (n=6), HFD and orally administered saline solution; and HFD+Q180 (n=6), HFD and orally administered L. plantarum Q180. After six weeks, the rate of increase of body weight was 13.7% lower in the HFD+Q180 group compared to the HFD group. In addition, the epididymal fat weights of the HFD+Q180 group were lower than that of the HFD group. The change of adipocyte size was measured in diet-induced obese mice. Consequently, the number of large-size adipose tissue was less distributed in the ND and HFD+Q180 groups than in the HFD group. L. plantarum Q180 has an effect on the inhibition of 3T3-L1 adipocyte differentiation, fat absorption and reduction of adipocyte size. L. plantarum Q180 could be applied to functional food products that help improve obesity.

• Steel and Composite Structures
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• v.18 no.6
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• pp.1517-1539
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• 2015

Eccentrically braced frames (EBFs) often use conventional steel with medium yield strength. This system requires structural members with large cross-sections for well seismic behavior, which leads to increased material costs. In eccentrically braced frames with high strength steel combination (HSS-EBFs), links use Q345 steel (specified nominal yield strength 345 MPa), braces use Q345 steel or high strength steel while other structural members use high strength steel (e.g., steel Q460 with the nominal yield strength of 460 MPa or steel Q690 with the nominal yield strength of 690 MPa). For this approach can result in reduced steel consumption and increased economic efficiency. Several finite element models of both HSS-EBFs and EBFs are established in this paper. Nonlinear hysteretic analyses and nonlinear time history analyses are conducted to compare seismic performance and economy of HSS-EBFs versus EBFs. Results indicate that the seismic performance of HSS-EBFs is slightly poorer than that of EBFs under the same design conditions, and HSS-EBFs satisfy seismic design codes and reduce material costs.

• Journal of Korean Neurosurgical Society
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• v.63 no.5
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• pp.579-589
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• 2020

Objective : No optimum genetic rat Huntington model both neuropathological using an adeno-associated virus (AAV-2) vector vector has been reported to date. We investigated whether direct infection of an AAV2 encoding a fragment of mutant huntingtin (AV2-82Q) into the rat striatum was useful for optimizing the Huntington rat model. Methods : We prepared ten unilateral models by injecting AAV2-82Q into the right striatum, as well as ten bilateral models. In each group, five rats were assigned to either the 2×10¹² genome copies (GC)/mL of AAV2-82Q (×1, low dose) or 2×10¹³ GC/mL of AAV2-82Q (×10, high dose) injection model. Ten unilateral and ten bilateral models injected with AAV-empty were also prepared as control groups. We performed cylinder and stepping tests 2, 4, 6, and 8 weeks after injection, tested EM48 positive mutant huntingtin aggregates. Results : The high dose of unilateral and bilateral AAV2-82Q model showed a greater decrease in performance on the stepping and cylinder tests. We also observed more prominent EM48-positive mutant huntingtin aggregates in the medium spiny neurons of the high dose of AAV2-82Q injected group. Conclusion : Based on the results from the present study, high dose of AAV2-82Q is the optimum titer for establishing a Huntington rat model. Delivery of high dose of human AAV2-82Q resulted in the manifestation of Huntington behaviors and optimum expression of the huntingtin protein in vivo.

• Journal of Power Electronics
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• v.1 no.2
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• pp.117-126
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• 2001

A synchronous motor(SM) with q-axis special field winding of which the q-axis field-current compensates and cancels armature reaction can be driven at unity power factor under the conditions of transient state as well as steady state. The motor operates in high efficiency in all conditions. However, in order to obtain maximum performance of the motor, it is required that the time constant of armature circuit corresponds to that of q-axis field circuit. Inverse LQ(ILQ) design method on a basis of the pole assignment is suitable for this problem:(1) The time constants of the output responses can be designed for desired specifications, (2) Relations between feedback gains and response of closed loop system are very clear and (3) Optimal solutions can be given by simple procedure of ILQ method without solving the Ricaati's equation, compared to the usual LQ design method. Accordingly, the ILQ method can make the responses of armature current and q-axis field-current correspond. In this paper, it is proved by numerical simulations and experiments that the ILQ method is very effective for optimal regulator design of this plant and realizes a high-performance motor with unity power factor and high efficiency.

• Communications for Statistical Applications and Methods
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• v.27 no.6
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• pp.701-714
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• 2020

Quantitative high throughput screening (qHTS) assays are used to assess toxicity for many chemicals in a short period by collectively analyzing them at several concentrations. Data are routinely analyzed using nonlinear regression models; however, we propose a new method to analyze qHTS data using a nonlinear mixed effects model. qHTS data are generated by repeating the same experiment several times for each chemical; therefor, they can be viewed as if they are repeated measures data and hence analyzed using a nonlinear mixed effects model which accounts for both intra- and inter-individual variabilities. Furthermore, we apply a one-step approach incorporating robust estimation methods to estimate fixed effect parameters and the variance-covariance structure since outliers or influential observations are not uncommon in qHTS data. The toxicity of chemicals from a qHTS assay is classified based on the significance of a parameter related to the efficacy of the chemicals using the proposed method. We evaluate the performance of the proposed method in terms of power and false discovery rate using simulation studies comparing with one existing method. The proposed method is illustrated using a dataset obtained from the National Toxicology Program.