• Nutrition Research and Practice
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• v.10 no.3
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• pp.336-341
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• 2016

BACKGROUND/OBJECTIVES: The incidence of thyroid cancer has increased in many countries, including Korea. International differences in the incidence of thyroid cancer may indicate a role of diet, but findings from previous studies are inconclusive. Therefore, we aimed to investigate the roles of nutrients in thyroid cancer risk in Korean women. SUBJECTS/METHODS: We conducted a case-control study comprising 113 cases and 226 age-matched controls. Nutrient intake was assessed using a validated food frequency questionnaire, and the association between nutrient intake and thyroid cancer risk was estimated using a logistic regression model. RESULTS: We found that high calcium intake was associated with a reduced risk of thyroid cancer (OR [95% CI] = 0.55 [0.35-0.89]). Significant associations were observed among subjects who were older than 50 years, had low BMI, and had low calorie intake. However, other nutrients included in this study did not show any significant associations with thyroid cancer risk. CONCLUSION: This study suggested a possible protective effect of calcium on thyroid cancer risk. Well-designed prospective studies are required to confirm these findings.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.31 no.2
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• pp.46-54
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• 2023

Helicopter pilots are required to perform many visual workloads in topographical avoidance, flight path modification and navigation, because helicopters operate at very low altitudes. The helicopter-specific instability also require the pilot to have precise perception and control. This has caused frequent human error in helicopter accidents. In Korea, two to three cases have occurred annually on average over the past 10 years, and this trend has not decreased. The purpose of this study was to identify human error risks in advance to prevent helicopter accidents and to help develop measures for missions and mission phases with high risk of human error. Through the study, the tasks and mission phases where accidents occur frequently were classified and the risk of human error was calculated for each mission phases. To this end, the task of frequent accidents during helicopter missions was first identified, detailed steps were classified, and the number of accidents was analyzed. Next, the AHP survey program was developed to measure the pilot's risk of human error and the survey was conducted on the pilots. Finally, the risk of human error by helicopter mission and by mission phases calculated and compared with the actual number of accidents.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.7
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• pp.3219-3222
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• 2012

A comparative study between 17 Japanese and 19 Indian patients with oral squamous cell carcinomas (OSCCs) revealed that the tumour prognostic indicator mean vessel density (MVD) count for angiogenesis was relatively high at 57.1 in Indian as compared to 39.3 in Japanese (P=0.001) cases, whereas the lymph-vessel density (LVD) count for lymphangiogenesis was lower (12.8 vs 48.0, P=0.002). Both male and female Indians had higher MVD counts, but LVD counts were only slightly lower in females. MVD count was relatively high among the cases below 65 years old in both the countries (P=0.4). Japanese cases with Tongue cancer had higher MVD count, but the Indian cases had lower LVD counts. Size-wise, T2 and T3 had higher counts of MVD both in Indian and Japanese cases. MVD and LVD count was higher in grades II and III both in Japanese and Indian cases. There was insignificant difference of the MVD counts among smokers, but the tobacco chewers in Indian cases had higher counts of MVD and LVD (P value by Bartlett test 0.35, 0.57 respectively). The hot-spots of tumour sites had variable rates of lymphocyte infiltration showed higher MVD counts in all the cases. Although the clinical characteristics and demographic variables usually relate to MVD and LVD counts, the tendency of higher values, especially among tobacco chewers, identified as the highest risk group for occurrence of oral cancer needs to be investigated further.

• Proceedings of the KSRS Conference
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• 2005.10a
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• pp.774-777
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• 2005

Dengue Fever(DF) and Dengue haemorrhagic fever(DHF) has become a major international public health concern. Dengue Fever(DF) and Dengue haemorrhagic Fever (DHF) is also still the major health problem of Thailand, although many campaigns against it have been conducted throughout the country. GIS and Remotely Sensed data are used to evaluate the relationships between socio-spatial, environmental factors/indicators and the incidences of viral diseases. The aim of the study is to identify the spatial risk factors in Dengue and Dengue Haemorrhagic Fever in Sukhothai province, Thailand using statistical, spatial and GIS Modelling. Preliminary results demonstrated that physical factors derived from remotely sensed data could indicate variation in physical risk factors affecting DF and DHF. The present study emphasizes the potential of remotely sensed data and GIS in spatial factors affecting Dengue Risk Zone analysis. The relationship between land cover and the cases of incidence of DF and DHF by information value method revaluated that highest information value is obtained for Built-up area. A negative relationship was observed for the forest area. The relations between climate data and cases of incidence have shown high correlation with rainfall factors in rainy season but poor correlation with temperature and relative humidity. The present study explores the potential of remotely sensed data and GIS in spatial analysis of factors affecting Dengue epidemic, strong spatial analysis tools of GIS. The capabilities of GIS for analyst spatial factors influencing risk zone has made it possible to apply spatial statistical analysis in Disease risk zone.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.2
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• pp.749-754
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• 2016

Extended follow-up of Hodgkin lymphoma (HL) survivors indicates that these patients are at high risk of secondary malignant neoplasms (SMNs) contributing to increased morbidity and mortality. This study examined the characteristics of HL survivors who developed SMNs with the aim to report any correlation with radiotherapy (RT) dose. In this retrospective multi-center cohort study of HL patients treated between 1990 and 2011 at three major teaching hospitals in Lebanon, classification was into two groups including those treated with combined modality (RT and chemotherapy-CHT) and those treated with CHT alone. Approval from the University Institutional Review Board (IRB) was obtained. Of the 112 patients evaluated, 52.7% (59) received the combined modality while 47.3% (53) received CHT alone. There were 6 cases of SMNs in the combined modality cohort and 5 cases in the CHT cohort. The mean RT dose in the combined modality cohort was 34.5 Gray (Gy) ($SD{\pm}5.3$). A statistically significant increase (1.5 fold) in the risk of developing SMNs was observed among patients who received a dose higher than 41 Gy compared to a dose between 20 to 30 Gy (OR= 1.5; 95% confidence interval= 0.674 to 3.339, p=0.012). The risk of SMNs was not significantly higher among patients who received extended field compared to involved field RT (p=0.964). This study showed that the risk of developing SMNs is higher among patients treated with RT dose greater than 31 Gy, independent of the RT type used.

• Journal of Chest Surgery
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• v.49 no.1
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• pp.22-28
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• 2016

Background: Carotid endarterectomy (CEA) with selective shunting is the surgical method currently used to treat patients with carotid artery disease. We evaluated the incidence of major postoperative complications in patients who underwent CEA with selective shunting under transcranial Doppler (TCD) at our institution. Methods: The records of 45 patients who underwent CEA with TCD-based selective shunting under general anesthesia from November 2009 to June 2015 were reviewed. The risk factors for postoperative complications were analyzed using univariate and multivariate analysis. Results: Preoperative atrial fibrillation was observed in three patients. Plaque ulceration was detected in 10 patients (22.2%) by preoperative computed tomography imaging. High-level stenosis was observed in 16 patients (35.5%), and 18 patients had contralateral stenosis. Twenty patients (44.4%) required shunt placement due to reduced TCD flow or a poor temporal window. The 30-day mortality rate was 2.2%. No cases of major stroke were observed in the 30 days after surgery, but four cases of minor stroke were noted. Univariate analysis showed that preoperative atrial fibrillation (odds ratio [OR], 40; p=0.018) and ex-smoker status (OR, 17.5; p=0.021) were statistically significant risk factors for a minor stroke in the 30-day postoperative period. Analogously, multivariate analysis also found that atrial fibrillation (p<0.001) and ex-smoker status (p=0.002) were significant risk factors for a minor stroke in the 30-day postoperative period. No variables were identified as risk factors for 30-day major stroke or death. No wound complications were found, although one (2.2%) of the patients suffered from a hypoglossal nerve injury. Conclusion: TCD-based CEA is a safe and reliable method to treat patients with carotid artery disease. Preoperative atrial fibrillation and ex-smoker status were found to increase the postoperative risk of a small embolism leading to a minor neurologic deficit.

• Journal of Korean Neurosurgical Society
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• v.62 no.5
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• pp.526-535
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• 2019

Objective : While the risk of aneurysmal rebleeding induced by catheter cerebral angiography is a serious concern and can delay angiography for a few hours after a subarachnoid hemorrhage (SAH), current angiographic technology and techniques have been much improved. Therefore, this study investigated the risk of aneurysmal rebleeding when using a recent angiographic technique immediately after SAH. Methods : Patients with acute SAH underwent immediate catheter angiography on admission. A four-vessel examination was conducted using a biplane digital subtraction angiography (DSA) system that applied a low injection rate and small volume of a diluted contrast, along with appropriate control of hypertension. Intra-angiographic aneurysmal rebleeding was diagnosed in cases of extravasation of the contrast medium during angiography or increased intracranial bleeding evident in flat-panel detector computed tomography scans. Results : In-hospital recurrent hemorrhages before definitive treatment to obliterate the ruptured aneurysm occurred in 11 of 266 patients (4.1%). Following a univariate analysis, a multivariate analysis using a logistic regression analysis revealed that modified Fisher grade 4 was a statistically significant risk factor for an in-hospital recurrent hemorrhage (p=0.032). Cerebral angiography after SAH was performed on 88 patients ${\leq}3$ hours, 74 patients between 3-6 hours, and 104 patients >6 hours. None of the time intervals showed any cases of intra-angiographic rebleeding. Moreover, even though the DSA ${\leq}3$ hours group included more patients with a poor clinical grade and modified Fisher grade 4, no case of aneurysmal rebleeding occurred during erebral angiography. Conclusion : Despite the high risk of aneurysmal rebleeding within a few hours after SAH, emergency cerebral angiography after SAH can be acceptable without increasing the risk of intra-angiographic rebleeding when using current angiographic techniques and equipment.

• Korean Journal of Construction Engineering and Management
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• v.14 no.4
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• pp.73-83
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• 2013

Recently, not only around Korea but also other countries shows a pattern of arising high-rise building construction project which was delayed or aborted during global economic crises and recession. Although the market starts to stretch, It is getting competitive to win a contract in high-rise construction project between contractors due to lack of competitive advantage especially to Korea contractors. To get that, Korean contractors needs lifting equipment plan. But currently, they depend on the empirical methods and that cause schedule delay, not controlled cost management problem. Therefore, this research is to improve the accuracy of Lifting plan by analyzing the current issues of Lifting plan system and deducing the types of failures with planning factors, as well as analyzing the impact on schedule and cost control and safety management by each failure mode. Also, by analyzing detail risk factors per Lifting Equipment with FMEA, to infer the critical risk factor on high-rise construction project.

• Earthquakes and Structures
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• v.22 no.6
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• pp.625-635
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• 2022

High-rise buildings (HRBs) are considered one of the most common structures nowadays due to the population growth, especially in crowded towns. The lack of land in crowded cities has led to the convergence of the HRBs and the absence of any gaps between them, especially in lands with weak soil (e.g., liquefaction-prone soil), but then during earthquakes, these structures may be exposed to the risk of collision between them due to the large increase in the horizontal displacements, which may be destructive in some cases to the one or both of these adjacent buildings. To evaluate methods of reducing the risk of collision between adjacent twin HRBs, this research investigates three vibration control methods to reduce the risk of collision due to five different earthquakes for the case of two adjacent reinforced concrete (RC) twin high-rise buildings of 15 floors height without gap distance between them, founded on raft foundation supported on piles inside a liquefaction-prone soil. Contact pounding elements between the two buildings (distributed at all floor levels and at the raft foundation level) are used to make the impact strength between the two buildings realistic. The mitigation methods investigated are the base isolation, the tuned mass damper (TMD) method (using traditional TMDs), and the pounding tuned mass damper (PTMD) method (using PTMDs connected between the two buildings). The results show that the PTMD method between the two adjacent RC twin high-rise buildings is more efficient than the other two methods in mitigating the earthquake-induced pounding risk.

• KIPS Transactions on Software and Data Engineering
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• v.9 no.11
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• pp.357-366
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• 2020

As the proportion and complexity of software embedded in aircraft increase, risk factors such as mission failure, function failure and performance failure due to software errors also increase. In the mission-critical software systems such as aircraft software, managing requirement traceability is essential to maintain the software systems with minimal period and cost. However, the development company is not accurately complying with the guideline for managing requirement traceability due to various reasons such as development cost and schedule. Therefore, it is not easy to systematically establish and maintain requirement traceability. In the paper, we analyze actual test cases of aviation software systems from the viewpoint of requirements traceability in order to learn if there are failure cases of test cases due to the absence of systematic traceability management activities. We also check the risks associated with the failure cases according to the type and severity of the cases. As a result of analyzing a total of 7 aircraft-mounted software, failure cases could be divided into three types: omission of requirements, lack of connection between requirements and test procedures, and omission of test procedures. There were a total of 18 failure cases, 6 for each type. The numbers of high, middle and low risks were 1, 13 and 4, respectively, where the number of middle risks is largest.