• Title/Summary/Keyword: high content screening

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Validity Study on the Early Screening Test for Birth-36 Month Old Children (0-36개월 영아발달선별 검사도구의 타당성에 대한 연구)

  • Seo, So-Jung;Ha, Ji-Young;Chang, Hye-Sung
    • Korean Journal of Child Studies
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    • v.29 no.5
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    • pp.13-30
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    • 2008
  • This study aimed to examine the reliability and validity of a diagnostic instrument to be used to measure the developmental level of very young children (aged birth through 36 months) and to screen young children at risk. The subjects of this study were 861 young children. Data were analyzed by item response distribution, item discrimination, reliability, and validity of the scale. Items reflected the developmental level of each age group. Overall internal consistency was relatively high (Cronbach's ${\alpha}=.90{\sim}.95$), and test-retest (after 2 weeks) reliability was high. Content validity was examined by a panel of experts in the related field. The construct validity as well as the concurrent validity of this instrument was also established.

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Screening Wheat Germplasm for high Amylose Content

  • Kyeong-Hoon Kim;Jinhee Park;Mina Kim;Kyeong-Min Kim;Yurim Kim;Go Eun Lee;Chon-Sik Kang;Jiyoung Shon;Jong-Min Ko
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.300-300
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    • 2022
  • Wheat (Triticum spp.) is an important source of food worldwide and the focus of considerable efforts to identify new combinations of genetic diversity for crop improvement. In particular, wheat starch composition is a major target for changes that could benefit human health. Starches with increased levels of amylose are of interest because of the correlation between high amylose content and elevated levels of resistant starch, which has been shown to have beneficial effects on health for combating obesity and diabetes. In this study, high amylose wheat germplasms from other countries were collected and cultivated in Korea, and then the content of amylose was evaluated, we examined amylose content in 614 wheat germplasm. Furthermore, amylose content was validated using several milling processes such as roller, hammer, and grinding mill. As a result, the amylose content distribution was divided into five groups. The range of the amylose levels in whole wheat flour was 18.3% to 29.6%. In addition, the mutant lines were screened for high amylose, and two mutant lines (WX-1046 and WX-1074) exhibited a comparable amylose content to Keumkang whole wheat (19.6%). It has been established that high amylose indicated SS IIa null and necessitate GBSS. Based on these findings, it may be helpful to develop high amylose wheat germplasm and production techniques, particularly in Korea.

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Assessment of the erosive potential of elder-friendly foods (액상형 고령친화식품의 치아부식능 평가)

  • Jung, Eun-Ha;Kang, Jung-Yun;Han, Sun-Young
    • Journal of Korean society of Dental Hygiene
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    • v.22 no.5
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    • pp.461-468
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    • 2022
  • Objectives: To investigate the effect of several elder-friendly foods on oral health and suggest guidelines for proper food intake. Methods: Six elderly-friendly foods (liquid type) and two control groups (mineral water and mixed coffee) were selected for this study. The pH of the food was measured using a calibrated pH meter, and the titratable acidity was determined using 1 M NaOH until 7.0 (TA 7.0). The screening method suggested by the International Organization for Standards was performed using an undersaturated hydroxyapatite solution to determine the difference between the initial and final pH of the screening solution (△pH). In addition, the sugar content was measured and expressed as Brix (%). Results: All the elder-friendly foods tested in this study showed a neutral pH (6.68-7.35), similar to mineral water (pH 7.84). The range of TA 7.0 values was 0.00-0.54 ㎖. The changes in pH determined using the screening solution confirmed that the largest change in pH was found in Careon (△pH 1.14±0.02), which has no erosive potential. Nevertheless, all elder-friendly foods had higher sugar content than the negative control group. Conclusions: Low tooth erosive potential was found in elder-friendly foods, but these foods showed high sugar content.

Selection and Characterization of Tomato Plants for Osmotic Stress Tolerance Derived from a Gamma Ray Irradiation (감마선 돌연변이원에 의한 Osmotic 스트레스 저항성 토마토 계통 선발 및 특성)

  • Kang, Kwon Kyoo;Jung, Yu Jin
    • Journal of Radiation Industry
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    • v.4 no.3
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    • pp.247-252
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    • 2010
  • The present study has been performed to select the osmotic tolerant lines using polyethylene glycol (PEG 6000) through an in vitro and in vivo mutagensis with a gamma-ray. During the screening, we selected three mutant lines that seemed to confer elevated osmotic tolerance in high concentrations of PEG 6000. Fruits of these mutants (Os-HK101, Os-HK102 and Os-HK103) were increased to sugar concentration, L-glutamine acid, vitamin C content and lycopine content than those of the wild type. Also the chlorophyll contents were few decreased more in the three mutant lines than the WT plants. Our results suggest that the Os-HK101 is characterized as osmotic stress tolerance considering the sugar concentration and lycopine content. It is expected that the result of this study can be used for breeding more competitive species with respect to contents in sugar or functional chemicals from the selected osmotic resistant lines.

A Study of Issues Related to Self-Directed Learning Screening(SDLS) in Science Specialized High School (과학고 자기주도학습전형 쟁점 연구)

  • Jung, Youn-Hong;Choe, Ho-Seong
    • Journal of The Korean Association For Science Education
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    • v.35 no.3
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    • pp.343-352
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    • 2015
  • This study is to discover the diverse issues related to Self-Directed Learning Screening (SDLS) and draw implications by analyzing its critical points. Using content analysis and interviews with admission officers, tentative issues were finalized and reviewed by researchers and educators. A Survey was developed based on the 96 issues after having evidence of content validity using the Delphi method. To conduct survey, e-mails were sent to admissions officers in twenty science specialized high schools. They were asked to response to questions about perceptions of critical issues and if there are any issues in their schools. Using mean scores of two factors based on its critical issues and frequencies, a two-dimensional classification table for each type was presented. Four critical issues for each type were discovered. The first type indicates minor issues that include 28 items that were less than the overall mean scores in terms of critical issues and its frequencies. The second type indicates tentative issues that include 29 items that were greater than the mean score in critical issues but less in its frequencies. The third type indicates general issues that include 17 items that were less than the mean score in critical issues but greater in its frequencies. The last type indicates critical issues that include 22 items that were greater than the mean scores in two factors. The discovered results of critical issues and its types in this study can be considered a core part of the screening process in schools, especially, critical issues should play an important role in the process of admission screening planning.

Generation and Evaluation of High ${\beta}$-Glucan Producing Mutant Strains of Sparassis crispa

  • Kim, Seung-Rak;Kang, Hyeon-Woo;Ro, Hyeon-Su
    • Mycobiology
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    • v.41 no.3
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    • pp.159-163
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    • 2013
  • A chemical mutagenesis technique was employed for development of mutant strains of Sparassis crispa targeting the shortened cultivation time and the high ${\beta}$-glucan content. The homogenized mycelial fragments of S. crispa IUM4010 strain were treated with 0.2 vol% methyl methanesulfonate, an alkylating agent, yielding 199 mutant strains. Subsequent screening in terms of growth and ${\beta}$-glucan content yielded two mutant strains, B4 and S7. Both mutants exhibited a significant increase in ${\beta}$-glucan productivity by producing 0.254 and 0.236 mg soluble ${\beta}$-glucan/mg dry cell weight for the B4 and S7 strains, respectively, whereas the wild type strain produced 0.102 mg soluble ${\beta}$-glucan/mg dry cell weight. The results demonstrate the usefulness of chemical mutagenesis for generation of mutant mushroom strains.

Characteristics of Carbonized Biomass Produced in a Manufacturing Process of Wood Charcoal Briquettes Using an Open Hearth Kiln (평로탄화로를 이용한 성형목탄 제조공정에서 생산된 탄화 바이오매스의 특성)

  • JU, Young Min;LEE, Hyung Won;KIM, Ah-ran;JEONG, Hanseob;CHEA, Kwang-Seok;LEE, Jaejung;AHN, Byoung-Jun;LEE, Soo Min
    • Journal of the Korean Wood Science and Technology
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    • v.48 no.2
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    • pp.181-195
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    • 2020
  • Characteristics of carbonized biomass obtained from a Wood charcoal briquette manufacturing process using an open hearth kiln are analyzed in this research, and differences in the characteristics based on the results of a mechanical screening process and the position within the kiln. One type of biomass and five types of carbonized biomass were collected from a Wood charcoal briquette manufacturer. After screening and grinding processes were performed on samples of 1 type of biomass and 5 types of carbonized biomass extracted from a Wood charcoal briquettes manufacturer to classify by particle size, fixed carbon, ash, volatile matters, elemental composition, and high heating value (HHV) were measured. Experimental results showed that the carbonized biomass collected from the middle layer had the highest HHV, 20.4 MJ/kg, and therefore had the highest fuel quality. In terms of particle size, the carbonized biomass below 100 mesh had the lowest ash content and the highest HHV, carbon content, and fixed carbon content. Correlation analyses showed that ash content had negative correlations with HHV, volatile matters, fixed carbon, and carbon content, which suggested that ash content affected negatively on fuel quality.

Perception of Breast Cancer Screening among Iranian Women without Experience of Mammography: A Qualitative Study

  • Khazaee-pool, Maryam;Majlessi, Fereshteh;Foroushani, Abbass Rahimi;Montazeri, Ali;Nedjat, Saharnaz;Shojaeizadeh, Davoud;Tol, Azare;Salimzadeh, Hamideh
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.9
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    • pp.3965-3971
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    • 2014
  • Background: In Iran, there are high rates of breast cancer. It is among the five most common cancers, the first among cancers diagnosed, and is the leading cause of cancer deaths among Iranian women. Objectives: The purpose of this qualitative study was to explore perception of breast cancer screening among Iranian women who have never had a mammograph. Materials and Methods: The current study was part of a qualitative research conducted by means of content analysis method and purposive sampling of 16 women over the age of 30 years who had not undergone mammography using individual semi-structured interviews. Interviews were recorded and transcribed verbatim. The data were under continuous consideration and comparative analysis in order to achieve data saturation. Results: After codification of data, three concept categories were achieved including: i) low awareness, ii) worries, and iii) lack of motivation. Conclusions: Although there is a tendency among Iranian women to participate in breast cancer screening, there is a powerful cultural belief that breasts are sexual organs that should not be discussed publicly. Due to the incidence of breast cancer in Iranian women, it is critical that breast awareness education be performed by health care experts to explore the concepts of breast cancer and breast cancer screening.

Development of Korean Intensive Care Delirium Screening Tool (KICDST) (중환자 섬망 선별도구 개발)

  • Nam, Ae-Ri-Na;Park, Jee-Won
    • Journal of Korean Academy of Nursing
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    • v.46 no.1
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    • pp.149-158
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    • 2016
  • Purpose: This study was done to develop of the Korean intensive care delirium screening tool (KICDST). Methods: The KICDST was developed in 5 steps: Configuration of conceptual frame, development of preliminary tool, pilot study, reliability and validity test, development of final KICDST. Reliability tests were done using degree of agreement between evaluators and internal consistency. For validity tests, CVI (Content Validity Index), ROC (Receiver Operating Characteristics) analysis, known group technique and factor analysis were used. Results: In the reliability test, the degree of agreement between evaluators showed .80~1.00 and the internal consistency was KR-20=.84. The CVI was .83~1.00. In ROC analysis, the AUC (Area Under the ROC Curve) was .98. Assessment score was 4 points. The values for sensitivity, specificity, correct classification rate, positive predictive value, and negative predictive value were found to be 95.0%, 93.7%, 94.4%, 95.0% and 93.7%, respectively. In the known group technique, the average delirium screening tool score of the non-delirium group was $1.25{\pm}0.99$ while that of delirium group was $5.07{\pm}1.89$ (t= - 16.33, p <.001). The factors were classified into 3 factors (cognitive change, symptom fluctuation, psychomotor retardation), which explained 67.4% of total variance. Conclusion: Findings show that the KICDST has high sensitivity and specificity. Therefore, this screening tool is recommended for early identification of delirium in intensive care patients.

Korean-American Women's Experience of Cancer Prevention in the U.S. (재미 한인 여성의 암 예방 경험)

  • Jun, Myunghee;Choi, Kyungsook;Kim, Hye-Kyung;Vipavee, Thongpriwan;Shin, Gyeyoung
    • Journal of muscle and joint health
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    • v.29 no.2
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    • pp.100-112
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    • 2022
  • Purpose: This study is a qualitative analysis of Korean-American (K-A) women's cancer prevention in the US. Methods: Qualitative research was conducted. Fifteen K-A women in four states were interviewed. Content theme analysis was used to analyze verbatim transcriptions of interviews. Results: Participants experienced difficulties in utilizing cancer screening programs. Factors include unfamiliarity with the US health care system, high health care costs or lack of health insurance, language barriers, and irregular and sporadic cancer screening participation. Participants also actively pursued non-institutional approaches to cancer prevention. They engaged in word-of-mouth informational exchanges in K-A communities, sought cancer screening in hospitals in Korea, conducted internet searches, autonomously decided on their health issues, and adopted healthy practices including better diets, physical exercise, and spiritual practices. Conclusion: It is necessary to implement measures to increase K-A women's utilization of the US cancer screening services and to encourage their active engagement in hands-on cancer prevention practices. K-A women should be empowered through increased familiarity with US cancer screening services and through the establishment of improved K-A community social services.