• 운동영양학회지
• /
• 제17권2호
• /
• pp.49-55
• /
• 2013

Our purpose was to investigate the effect of a 5-week high-fat diet on the body weight, blood components [triglycerides (TGs), free fatty acids (FFAs), and glucose], and lipoprotein lipase (LPL) mRNA expression in the skeletal muscles of rats. Body weight increased overtime in experimental and control groups without significant differences. In terms of the blood components, the density of TG was significantly lower in the high-fat diet group compared to the control, whereas FFA and glucose levels were similar in the two groups. Although the levels of glyceraldehyde 3-phosphate dehydrogenase(GAPDH) mRNA expression were similar between the groups, LPL mRNA expression was significantly higher in the high-fat diet group than that in the control group. The results of this study suggest that a high-fat diet enhances LPL mRNA expression, as well as possibly increases fat metabolism. For a better understanding of the relationship between diet patterns and fat metabolism, further analysis of genes related to the fat metabolism is warranted.

• 공업화학
• /
• 제7권3호
• /
• pp.554-564
• /
• 1996

페롭스카이트 $La_{0.6}Sr_{0.4}Co_{1-x}Fe_xO_3$(x=0.00, 0.01, 0.10, 0.20, 0.35, 및 0.50)를 산소전극물질로 사용하여 알칼리형 연료전지에서의 산소환원반응을 연구하였다. Fe치환에 따른 촉매특성의 변화를 X-선회절분석법(XRD), 열중량분석법(TG) 및 승온환원법(TPR)을 통하여 조사하였다. XRD 구조분석을 통하여 페롭스카이트 단위격자의 격자상수값을 측정할 수 있었다. TG 실험결과 Fe는 페롭스카이트 구조내에서 크게 안정화되어 $900^{\circ}C$까지 거의 환원되지 않았고, Fe치환량 증가에 따라 Co-O간의 결합에너지가 증가하여 고온에서 제거되는 산소종의 양이 증가하였다. TPR 실험결과, ${\alpha}$-(저온피크)와 ${\beta}$-(고온피크)산소종이 존재하였다. ${\beta}$-산소종은 Co와 강하게 결합되어 있는 산소종으로서 Fe치환량 증가에 따라 결합세기가 증가하였다. ${\alpha}$-산소종은 가역적으로 격자내외를 출입하는 산소환원반응의 활성종이었으며, Fe치환량 증가에 따른 격자상수의 증가는 금속과 ${\alpha}$-산소종간의 결합에너지로 볼 수 있는 ${\alpha}$산소종의 환원피크를 저온으로 이동시킴으로써 산소환원반응의 활성을 증가시켰다. 반면에, Fe치환량 증가에 따른 ${\alpha}$-산소종의 감소는 산소환원반응의 활성을 감소시켰으며, Fe치환에 따른 표면적의 증가는 반응활성에 크게 영향을 미치지 못하였다.

• 한국식품영양학회지
• /
• 제24권4호
• /
• pp.622-629
• /
• 2011

This study was performed to investigate the effect of rice bran dietary fiber powder on serum lipid levels, bowel function, and mineral absorption in rats. Four weeks old male Sprague Dawley rats(SD rat) were divided into four groups : control group fed 5% cellulose as a fiber source, RB10 fed 5% of cellulose and 10% of rice bran dietary fiber powder, RB20 and RB30. The animals were fed the experimental diets for 4 weeks. Serum lipid levels were not significantly different among the groups. But, fecal total cholesterol(TC), triglycerides(TG), and high density lipoprotein cholesterol(HDL-c) excretion increased in the RB30 group. Fecal weight and fecal water content were higher in the rice bran added groups than those in the control group. Transit time was significantly shorter in the rice bran fiber-added groups than that in the control. Weight of the stomach and large intestine in the RB20 and RB30 groups were significantly greater than those in the other groups. Absorption rates of Ca, Mg, P, and Zn decreased significantly in the RB30 group compared to those in the other groups. A high amount of rice bran increased fecal lipids, including TC, TG and HDL-c. Rice bran increased fecal weight and fecal water content and shortened gastrointestinal transit time. However, a high level of rice bran diet decreased mineral absorption rates.

• 한국통신학회논문지
• /
• 제34권6C호
• /
• pp.561-570
• /
• 2009

임펄스 기반의 초광대역 통신 기술은 이론적으로 근거리에서 고속의 데이터 전송과 고해상도의 거리 인지 및 무선 측위가 가능하다는 장점을 가지고 있지만 이러한 기능들을 수행하기 위해서는 우선적으로 고속의 ADC(Analog to Digital Convertor)가 요구되며 특히, 시간 기반의 무선 측위 기법을 적용할 경우 더욱 그러하다. 그러나 현실적으로 GHz 이상의 고속의 ADC는 매우 고가이기 때문에 본 논문에서 목표로 하는 저비용을 고려한 저속의 무선 개인 영역 네트워크 (Low Rate - Wireless Personal Area Network; LR-WPAN)에서는 부적합하다. 따라서 본 논문에서는 저속의 ADC로 고정밀의 무선 측위가 가능한 주파수 영역에서 계산의 복잡도가 낮은 AR(Auto Regressive) 모델을 기반으로한 레인징 기법을 소개하고, 아날로그 단에서 주파수 변환을 위해 카운터를 이용한 VCO(Voltage Control Oscillator) 방식의 non-coherent 기반의 수신 구조를 제안한다. 제안된 기법에 대한 성능을 검증하기 위해서 IEEE 802.15.4a TG에서 제시한 채널 모델을 적용하였으며 시뮬레이션 결과로부터 제안된 레인징 및 측위 방안의 우수성을 검증하였다.

• Nutrition Research and Practice
• /
• 제7권2호
• /
• pp.139-145
• /
• 2013

There is a lack of data on metabolic risk factors during pre-puberty, which is important for identifying the subgroups of youth, at whom early interventions should be targeted. In this study, we evaluated the prevalence of metabolic risk factors and its subsequent relations with dietary patterns in Korean pre-pubertal children through a cross-sectional sample (n = 1,008; boys = 513) of pre-pubertal children (aged 8-9 years) from a sub-study of the Korea Metabolic Syndrome Research Initiatives (KMSRI) in Seoul, Korea. Measures of anthropometry and blood pressure as well as fasting blood samples were used in the analysis. A three-day food records were collected. The metabolic syndrome was defined according to the age-adjusted National Cholesterol Education Program Adult Treatment Panel III guidelines. An added metabolic risk score was calculated for each subject by summing the quintile values of the five individual risk factors. Among the 5 risk components of metabolic syndrome, high waist circumference (WC) was the major factor (P < 0.001). A significant increasing trend of the added metabolic syndrome risk score was observed with the increase of WC (P (trend) < 0.001) among both genders. The cutoff point for high WC for pre-pubertal children was 61.3 cm for boys and 59.9 cm for girls. The prevalence of high triglyceride (TG) values was significantly higher in girls than it was in boys (P < 0.01). Girls in the highest quintile of balanced dietary pattern scores had lower TG values (P (trend) = 0.032) than did those in the lowest quintile. Moreover, girls in the highest quintile of western dietary pattern scores showed increasing trend for the added metabolic risk score (P (trend) = 0.026) compared with those in the lowest quintile. Adverse associations exist between western dietary patterns and the accumulation of metabolic risks among girls, not in boys, even during pre-puberty.

• 한국통신학회논문지
• /
• 제32권3A호
• /
• pp.230-236
• /
• 2007

본 논문에서는 IEEE 802.15.3 High-Rate WPAN(Wireless Personal Area Network)의 메쉬 네트워크 구성을 위한 분산형 채널 자원 관리 방법을 제안한다. IEEE 802.15 TG(task group)5는 WPAM의 메쉬 네트워크 구성을 위해 MAC과 PHY 계층의 표준화를 진행중이다. 기존 WPAN에서 전송 파워의 증가나 수신측의 감도 증가없이 전송 범위 확장 방법의 연구와 네트워크 내에서 라우팅 기능의 강화를 통해서 보다 신뢰성 있는 통신을 가능케하는 것이 이 TG의 목표이다. 본 논문은 PNC(piconet coordinator)가 없이 각 DEV(device)들이 자신의 채널 자원을 예약하는 환경에서 DEV들이 공평하게 채널 자원을 사용하는 방법을 제안한다. 채널자원을 분배하는 PNC가 없으면 각 DEV는 자신이 사용할 채널자원을 미리 예약하여 사용한다. Piconet에 먼저 접속한 DEV는 많은 양의 채널자원 예약이 가능하지만 나중에 접속한 DEV는 상대적으로 적은 양의 채널자원만 예약할 수 있다. 이처럼 기존 방법에서는 DEV들이 공평하게 채널자원을 사용하지 못하는 문제점이 발생한다. 본 논문에서는 MAC 계층에서 채널 자원 할당의 불공평함을 해결하는 분산형 채널타임 할당 방법을 제안하고, 시뮬레이션을 통해서 자원 할당 방법의 성능을 평가한다.

• 한국통신학회논문지
• /
• 제34권2C호
• /
• pp.145-152
• /
• 2009

임펄스 기반의 초광대역 통신 기술은 이론적으로 근거리에서 고속의 데이터 전송과 고해상도의 거리 인지 및 무선 측위가 가능하다는 장점을 가지고 있지만 이러한 기능들을 수행하기 위해서는 우선적으로 고속의 ADC (Analog to Digital Convertor)가 요구되며 특히, 시간 기반의 무선 측위 기법을 적용할 경우 더욱 그러하다. 그러나 현실적으로 GHz 이상의 고속의 ADC는 매우 고가이기 때문에 본 논문에서 목표로 하는 저비용을 고려한 저속의 무선 개인 영역 네트워크 (Low Rate - Wireless Personal Area Network; LR-WPAN)에서는 부적합하다. 따라서 본 논문에서는 저속의 ADC로 고정밀의 무선 측위가 가능한 주파수 영역에서의 측위 기법을 소개하고 아날로그 단에서 주파수 변환을 위해 FM (Frequency Modulation) 방식을 접목시킨 새로운 형태의 non-coherent 기반의 수신 구조를 제안한다. 제안된 기법에 대한 성능을 검증하기 위해서 IEEE 802.15.4a TG에서 제시한 채널 모델을 적용하였으며 시뮬레이션 결과로부터 제안된 방안의 우수성을 검증하였다.

• 대한물리치료과학회지
• /
• 제6권2호
• /
• pp.1019-1040
• /
• 1999

The purpose of this study is to clarify the repercussions of swimming exercise therapy that has an effect on lipid in blood and liver enzyme of the 3D-Rat dosage high fat diet. The object of this study consisted of two groups. One was the swimming exercise SD-Rat group, the other was the non-exercise SD-Rat group. Sample size was seven Rats repectively. Exercise period was ten week. Exercise group swimmed twenty minutes per a day and 5 times per a week. And then collecting blood from these two group's SD-Rats, making M Health center a request for a blood test on TC, TG, GOT, GPT, we come to a conclusion like below. The weight of the swimming exercise group has decreased 5.93% in comparison with non-exercise group. and has a significant difference(p<0.05). The liver weight of the swimming exercise group has decreased 7.83% in comparison with non-exercise group, and has not a significant difference. The TC of the swimming exercise group has decreased 39.22% in comparison with non-exercise group, and has a significant difference(p<0.05). The TG of the swimming exercise group has decreased 62.88% in comparison with non-exercise group, and has a significant difference(p<0.05). The GOT of the swimming exercise group has decreased 3.22% in comparison with non-exercise group, and has not a significant difference. The GPT of the swimming exercise group has decreased 16.14% in comparison with non-exercise group, and has a significant difference(p<0.05). In regard to above results, the regular swimming exercise therapy with dosage of high fat diet has an important role in healing and preventing a fattyliver, a hyperlipidemia, and an arteriosclerosis, intervening the lipid in blood.

• 대한본초학회지
• /
• 제39권1호
• /
• pp.11-21
• /
• 2024

Objectives : This study aims to analyze the anti-obesity effect of Syzygium aromaticum L. (SA) in obese mice made by a 60% high-fat diet (HFD). Methods : The antioxidant activities of SA were evaluated in vitro. To assess the anti-obesity effect of SA, male C57BL/6 mice were divided into five groups: Normal, Control, GC100 (Garcinia cambogia 100 mg/kg/day), SA100 (SA 100 mg/kg/day), SA200 (SA 200 mg/kg/day). All groups underwent a 6-week regimen of HFD and oral administration, except for the Normal group. Subsequently, we performed blood analysis, western blotting, and histopathological staining. Results : SA demonstrated effectiveness in antioxidant measurements. SA treatment resulted in a significant decrease in body weight gain, along with reductions in liver and epididymal fat weights. Serum triglyceride (TG), total cholesterol (TC), glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), and leptin levels were reduced with SA treatment. Moreover, in the SA100 group, the reduction of both TG and TC synthesis was caused by inhibiting the sterol regulatory element-binding transcription factor 1 (SREBP-1) and sterol regulatory element-binding transcription factor 2 (SREBP-2) through the Sirtuin 1 (Sirt1)/phospho-AMP-activated protein kinase (p-AMPK) pathway. Furthermore, SA treatment at a dose of 100 mg/kg reduced the accumulation of lipid droplets in the liver and the adipocyte size of the epididymal fat. Conclusion : Our research reveals the anti-obesity effects of SA by demonstrating its ability to inhibit body weight gain and lipid accumulation, suggesting that SA might be promising for obesity treatment.

• 대한한방내과학회지
• /
• 제28권4호
• /
• pp.830-837
• /
• 2007

Background and purpose : Stroke is one of the most deadly diseases and a leading cause of disability. Lipids confer an increased risk for cardiovascular morbidity and mortality. In spite of many studies on the relationship between stroke and lipids, their relationship is not clear. This study was undertaken to determine whether lipids were associated with stroke. Method : We compared the components of blood lipids between stroke patients group (n=217,Cases), non-stroke control group (n=160, Controls) and healthy control group without hypertension, diabetes mellitus, ischemic heart disease, or hyperlipidemia (n=140, Normals). These data were statically analyzed by general linear models and binary logistic regression analysis to get each adjusted odds ratio. Result : The results were as follows. The blood levels of total cholesterol (T-Chol), triglyceride (TG) and low density lipoprotein cholesterol (LDL-Chol) were significantly higher in patients of ischemic stroke, while the blood levels of T-Chol and LDL-Chol were significantly lower, and the blood levels of TG significantly higher in patients of hemorrhagic stroke. The blood level of high density lipoprotein cholesterol (HDL-Chol) was significantly lower in all cases. Conclusion : These results suggest that high TG and low HDL-Chol may be risk factors of hemorrhagic stroke and ischemic stroke, high T-Chol and LDL-Chol may be risk factors of ischemic stroke, and low T-Chol and LDL-Chol may be risk factors of hemorrhagic stroke in Koreans.