The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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A Case-Control Study on Blood Lipids as a Risk Factor of Stroke

뇌졸중 위험지표로서의 혈중 지질에 대한 환자;대조군 연구

  • Kim, Jung-Hyun (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kang, Kyung-Won (Dept. of Medical Research, Korea Institute of Oriental Medicine) ;
  • Yu, Byeong-Chan (Dept. of Medical Research, Korea Institute of Oriental Medicine) ;
  • Choi, Sun-Mi (Dept. of Medical Research, Korea Institute of Oriental Medicine) ;
  • Baek, Hye-Ki (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Lim, Seung-Min (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • An, Jung-Jo (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Seol, In-Chan (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kim, Yoon-Sik (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University)
  • 김정현 (대전대학교부속한방병원 심계내과학교실) ;
  • 강경원 (한국한의학연구원 의료연구부) ;
  • 유병찬 (한국한의학연구원 의료연구부) ;
  • 최선미 (한국한의학연구원 의료연구부) ;
  • 백혜기 (대전대학교부속한방병원 심계내과학교실) ;
  • 임승민 (대전대학교부속한방병원 심계내과학교실) ;
  • 안정조 (대전대학교부속한방병원 심계내과학교실) ;
  • 설인찬 (대전대학교부속한방병원 심계내과학교실) ;
  • 김윤식 (대전대학교부속한방병원 심계내과학교실)
  • Published : 2007.12.30
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Abstract

Background and purpose : Stroke is one of the most deadly diseases and a leading cause of disability. Lipids confer an increased risk for cardiovascular morbidity and mortality. In spite of many studies on the relationship between stroke and lipids, their relationship is not clear. This study was undertaken to determine whether lipids were associated with stroke. Method : We compared the components of blood lipids between stroke patients group (n=217,Cases), non-stroke control group (n=160, Controls) and healthy control group without hypertension, diabetes mellitus, ischemic heart disease, or hyperlipidemia (n=140, Normals). These data were statically analyzed by general linear models and binary logistic regression analysis to get each adjusted odds ratio. Result : The results were as follows. The blood levels of total cholesterol (T-Chol), triglyceride (TG) and low density lipoprotein cholesterol (LDL-Chol) were significantly higher in patients of ischemic stroke, while the blood levels of T-Chol and LDL-Chol were significantly lower, and the blood levels of TG significantly higher in patients of hemorrhagic stroke. The blood level of high density lipoprotein cholesterol (HDL-Chol) was significantly lower in all cases. Conclusion : These results suggest that high TG and low HDL-Chol may be risk factors of hemorrhagic stroke and ischemic stroke, high T-Chol and LDL-Chol may be risk factors of ischemic stroke, and low T-Chol and LDL-Chol may be risk factors of hemorrhagic stroke in Koreans.

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