• Title/Summary/Keyword: hibiscus extract

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Screening of Acyl-CoA:Cholesterol Acyltransferase(ACAT) Inhibitors from Natural Sources (천연자원으로부터 아실코에이: 콜레스테롤아실 전달효소 저해제의 탐색)

  • Kim, Mi-Kyung;Kwon, Byoung-Mog;Bae, Ki-Hwan;Choi, Don-Ha;Lee, Hak-Ju;Kim, Hong-Eun;Kim, Young-Kook
    • Korean Journal of Pharmacognosy
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    • v.30 no.4
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    • pp.384-396
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    • 1999
  • Acyl-CoA: Cholesterol Acyltransferase (ACAT) is a key enzyme responsible for cholesteryl ester formation in atherogenesis and in cholesterol absorption from the intestines. In addition under pathological conditions, formation and accumulation of cholesteryl ester as lipid droplets by ACAT within macrophages constitute a characteristic feature of early lesions of atherosclerotic plaques. ACAT inhibitors are expected to be effective for treatment of atherosclerosis and hypercholesterolemia. ACAT inhibitors of natural origin have been rarely reported. In our screening program for ACAT inhibitors, 303 plants were extracted with methanol or ethanol, and screened for the inhibitory activity against ACAT from the rat liver microsome. Extracts of 13 plants including Quercus aliena, Diospyros kaki, Platycarya strobilacea and Hibiscus syriacus inhibited more than 90% of ACAT activity and 43 samples in alcohol extracts such as Magnolia obovata and Panax ginseng also inhibited more than 70% of ACAT activity at a concentration of $100\;{\mu}g/ml$.

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In vitro and in vivo evaluation of kenaf (Hibiscus cannabinus L.) as a roughage source for beef cattle

  • Oh, Seongjin;Mbiriri, David Tinotenda;Ryu, Chaehwa;Lee, Kangheon;Cho, Sangbuem;Choi, Nag-Jin
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.10
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    • pp.1598-1603
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    • 2018
  • Objective: The goal of this study was to evaluate kenaf as a roughage source in vitro and its effects on meat quality of Hanwoo (Korean native) cattle. Methods: Three roughage materials, rice straw silage, ryegrass silage, and kenaf silage, were tested in a batch culture and feeding trial. Rumen fermentation parameters, including gas, pH, volatile fatty acid (VFA), and ammonia were analyzed. In the feeding trial, Hanwoo steers ($373.5{\pm}5.1kg$, n = 36, 11 month of age) were divided into three feeding groups (n = 12 each). Animals were fed with each silage and concentrate until the fattening stage. Results: Crude protein, ether extract, and non-structural carbohydrates were greater in kenaf silage. Total gas production was higher in ryegrass silage, followed by kenaf silage and rice straw silage (p<0.05). Total VFA and individual VFA (acetate, propionate, and n-butyrate) were greater in kenaf silage than rice straw silage (p<0.05). In vitro dry matter digestibility showed a similar trend to that of total gas and VFA production; it was higher in ryegrass silage and lower in rice straw (p<0.05). Throughout the feeding trial, the rice straw silage group showed significantly greater average daily gain than did the others (p<0.05). The feed conversion ratio in the group fed kenaf silage was significantly greater than that of others (p<0.05). No significant differences were observed in yield or quality traits, including carcass weight, ribeye area, backfat thickness, and scores for marbling, meat color, and fat color (p>0.05). Conclusion: The results indicated that no negative effects on growth performance and carcass characteristics occurred across treatments. Therefore, kenaf could be substituted for rice straw, which is most widely used as a roughage source in Korea.

Effect of Number of Plants per Hill on the Agronomic Characteristics, Forage Yield, and Chemical Camposition of Kenaf in Jeiu Region (제주지역에서 주당본수에 따른 양마의 생육특성, 사료수량 및 조성분 변화)

  • 조남기;강영길;송창길;조영일;고미라;오은경
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.22 no.1
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    • pp.23-30
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    • 2002
  • Eveuadies 71' kenaf (Hibiscus cannabinus L.) was grown at five plant densities (1, 2, 3, 4, and 5 plants per hill; 16,000, 32,000, 48,000, 64,000 and 80,000 plants/10a) from April 13 to October 8, 2001 in Jeju island to determine influence of plant number per hill on agronomic characteristics, forage yield and quality. As plant density increased from 1 to 5 plants per hill, the plant height averaged across two harvests increased 176 to 185 cm. Compared with the plant density of two plants per hill, the plant height decreased at higher plant densities (183, 180, and 166 cm for 3, 4 and 5 plants per hill). The highest yield of fresh forage (114.6 MT/ha), dry matter (17.3 MT/ha), crude protein (2.33 MT/ha), and total digestible nutrients (TDN) (9.21 MT/ha) was obtained at 2 plants per hill. As plant density increased from 1 to 5 plants per hill, crude protein, ether extract, nitrogen free extract, and TDN contents increased from 13.1 to 15.4%, 3.0 to 3.7%, 20.1 to 23.2% and 41.1 to 45.4%, respectively, while crude fiber and crude ash contents decreased from 41.2 to 34.9% and 9.4 to 8.2%, respectively.

Effects of Cutting Height on Agronomic Characteristics, Forage Yield, and Chemical Composition of Kenaf in Jeju (제주지역에서 예취높이에 따른 양마의 생육특성, 사료수량 및 조성분 변화)

  • 조남기;강영길;송창길;조영일;오은경;고미라;박정식
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.22 no.1
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    • pp.15-22
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    • 2002
  • This study was conducted from April 13 to October 8, 2001 in Jeju to determine the influence of cutting height (2, 4, 6, 8 and 10 cm from the soil surface) on growth, forage yield and chemical composition of kenaf (Hibiscus cannabinus L.). As cutting height was increased from 2 to 10 cm, plant height averaged across two cuttings increased from 157.7 to 184.7 cm. This pattern held fir the number of leaves and branches per plant, stem diameter and plant weight per plant. As cutting height increased from 2 to 10 cm, fresh forage, dry matter, crude protein and TDN yields increased from 85.5 to 113.7MT/ha, from 11.97 to 15.63 MT/ha, from 1.63 to 2.72, and from 4.95 to 7.54 MT/ha, respectively. As cutting height was increased from 2 cm to 10 cm, crude protein, ether extract, nitrogen free extract, and TDN contents increased from 14.2 to 17.6%, 2.9 to 3.9%, 24.2 to 25.8% and 43.1 to 48.5%, respectively, while crude fiber and crude ash contents decreased from 35.5 to 30.4 % and 9.9 to 8.1 %, respectively.

Effects of Split Nitrogen Application on Agronomic Characteristics, Forage Yield, and Chemical Composition of Kenaf in Jeju (제주지역에서 질소분시 횟수에 따른 양마의 생육특성, 사료수량 및 조성분 변화)

  • 조남기;강영길;송창길;조영일;정재수;고미라;오은경
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.22 no.1
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    • pp.9-14
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    • 2002
  • Evegradies 71' kenaf (Hibiscus cannabinus L.) was grown at 160,000 plants per ha in a volcanic ash soil in Jeju island to determine the optimum frequency of split N application fer forage production. Nitrogen fertilizer was applied with 240 kg/ha, and frequencies of the split N applications were 1, 2, 3, 4 and 5 times. Plant height averaged across two harvests increased from 187 to 201cm as N was split-applied from one to three applications and then decreased to 201cm in five applications. This pattern held for the number of branches and leaves per plant stem diameter and weight of plant per plant. Fresh forage yield increased from 91.8 to 114.2 MT/ha. dry matter yield from 12.70 to 16.6 MT/ha, crude protein yield from 1.75 to 2.48MT/ha, and total digestible nutrients (TDN) yield from 5.39 to 7.63 MT/ha as N was split-applied from one to four applications, and then decreased to 106.6, 15.0, 2.32, and 7.22 MT/ha in five applications, respectively As N was split-applied from one to five applications, crude protein content increased from 13.8 to 15.4%. ether extract content from 4.1 to 5.9%, and TDN content from 42.4 to 48.1%. but crude fiber decreased from 38.2 to 37.1% and crude ash content from 11.5 to 8.6%. Nitrogen free extract content was about 19.0% regardless of cutting height.

Oral administration of H. syriacus L. flower ameliorates photoaging and dryness in UVB-irradiated skin (무궁화 꽃 추출물 경구투여에 의한 피부 광노화 및 건조증 개선에 관한 효과)

  • Yang, Jung-Eun;Seo, Seul A;Kang, Min Cheol;Yoon, Da Hye;Im, Tae Joon;Hwang, Eunson;Won, Kyung Hwa;Lee, Teak Hwan;Kim, Sun Yeou
    • Korean Journal of Food Science and Technology
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    • v.53 no.4
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    • pp.399-407
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    • 2021
  • Wrinkle formation and dryness are the most well-known symptoms of skin aging. This study investigated skin anti-aging and moisturizing effects of Mugunghwa (Hibiscus syriacus L.), the national flower of Korea. The effect of H. syriacus L. flower extract was examined in skin cells originating from humans in vitro and in hairless mice exposed to UVB in vivo. The in vivo study results showed that skin hydration-related factors such as involucrin, filaggrin, HAS1, HYAL1, and matrix metalloproteinase-I (a primary skin photoaging factor) were regulated by H. syriacus L. Additionally, epidermal thickness and collagen disruption, which resulted in wrinkle formation and skin dryness, were ameliorated by oral administration of H. syriacus L. These results indicate that H. syriacus L. flowers can play important roles in preventing aging and promoting skin moisturizing.

Biomaterials Inhibiting Biofilm Formation of Staphylococcus aureus (생물소재를 이용한 황색포도상구균의 바이오필름 억제 연구)

  • Shin, Kye-Ho;Yun, Yu-Na;Jeon, Gi-Boong;Lee, Tae-Ryong;Yi, Sung-Won;Cho, Jun-Cheol;Park, Ji-Yong
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.37 no.4
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    • pp.347-350
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    • 2011
  • Biofilms are surface-attached microbial communities with phenotypic and biochemical properties distinct from free-living planktonic cells. Biofilm bacteria show much greater resistance than planktonic counterparts and much higher concentration of biocide is needed to treat biofilms compared to the dosage used for planktonic bacteria. As a result, alternative strategies or more effective agents exhibiting activity against biofilm-producing micro-organisms are of great interest. Therefore, we turned our attention to control of biofilm of S. aureus. The aims of this research are to investigate substances which inhibit the formation of biofilm by S. aureus and to suggest effective materials for controlling skin problems. We coated slide glasses with human placental collagen and the coverslip was incubated with test materials and bacteria. The coverslip was stained with crystal violet and we measured optical density of each sample. The biofilm inhibitory activity was calculated by crystal violet staining degrees. In this study, S. aureus ATCC 6538 was used as test organism. Our results show that both water soluble and insoluble Hinoki cypress polysaccharide strongly inhibited biofilm formation. Whereas, green tea and sunset hibiscus root extract promoted biofilm. Xylitol showed a concentration dependent effect; high concentration (3 % and 5 %) of xylitol reduced biofilm while promoted biofilm formation at a concentration of 1 %. These results support that Hinoki cypress polysaccharide and xylitol have ability to suppress biofilm formation.

Effect of Seeding Date on Forage Yield and Chemical Composition of Kenaf in Jeju (제주지역에서 파종기에 따른 양마의 사료수량 및 조성분 변화)

  • 조남기;송창길;조영일;고지병
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.46 no.6
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    • pp.439-442
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    • 2001
  • This study has been conducted from April 25, 1999 to June 25, 1999 in Jeju Province in order to determine the influence of seeding date on growth, yield and chemical composition of Kenaf (Hibiscus cannabinus L.) Delaying the seeding date from April 25 to June 25 decreased the plant height of Kenaf from 278.5 cm to 205.7 cm. As for the number of leaves, number of withering leaves, number of branches, and stem diameter decreased as the seeding date was delayed. As the seeding date was delayed, fresh forage yield decreased from 98.5MT/㏊ to 45.9MT/㏊, dry matter yield from 20.7MT/㏊ to 8.2MT/㏊, crude protein (CP) yield from 2.9MT/ha to 1.3MT/ha and total digestible nutrients (TDN) yield form 1l.6MT/㏊ to 5MT/㏊. However, both leaf yield and stem yield were nearly the same tendency. Delaying the seeding date from April 25 to June 25 increased crude protein contents of leaves from 21.5% to 24.4%, crude fat contents from 5.2% to 6.1%, nitrogen free extract (NFE) contents form 39.9% to 41.2% and TDN contents from 64.3% to 69.7%. However, delaying seeding date decreased crude fiber contents from 20.8% to 17.5%, and crude ash contents from 7.9% to 7.0%. Based on the these findings, optimum seeding date for forage production of Kenaf seems to be about 25 April in atmospheric phenomena and volcanic ash soils of Jeju island.

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