• Plant Biotechnology Reports
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• v.2 no.3
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• pp.213-218
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• 2008

Swertia chirata is an endangered gentian species that prefers to grow at higher altitudes. This ethnomedicinal herb is known primarily for its bitter taste caused by the presence of important phytochemicals that are directly associated with human health benefits. Due to a continuous loss of habitat and inherent problems of seed viability and seed germination, alternative strategies for propagation and conservation are urgently required to prevent the possible extinction of this species. We have formulated a reproducible protocol for the rapid propagation and conservation of this plant using leaves taken from in vitro shoot cultures. Direct induction of more than seven shoot buds per explant was achieved for the first time when the explants were placed on MS medium supplemented with $2.22{\mu}M$ N-6-benzyladenine, $11.6{\mu}M$ kinetin, and $0.5{\mu}M$ ${\alpha}-naphthalene$ acetic acid. Direct organogenesis was noted exclusively from the adaxial surface of the basal segments of leaves. Leaves closer to the apical meristem were more responsive than those farther away from the meristem. Plants raised through direct organogenesis were evaluated for their clonal fidelity by chromosomal analysis and DNA fingerprinting. Complete plants were successfully transferred to the field condition and produced viable seeds. Given the enormous potential of this age-old medicinal plant in terms of potential health-benefitting drugs, this protocol can be used for commercial propagation purposes and to initiate future genetic improvement studies.

• Korean Journal of Oriental Medicine
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• v.16 no.3
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• pp.95-105
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• 2010

Background and Purpose : Forest-Therapy has received attention as a treatment of regulating living habits with the increase of chronic disease. Forest-Therapy and Korean Medicine are in same as their philosophy to adapt to nature and they can suggest new alternative treating of chronic diseases. Now we want to look the possibility of development of Forest-Therapy program adopting Korean Medicine with the analysis of research status and cases of Forest-Therapy. Methods : We searched articles in Korea by using keyword 'Forest-Therapy', 'Forest & Therapy' 'Forest' and 'Therapy' Korean. Results : Even though the domestic research about Forest-Therapy is still insufficient, there is a need of try referring the cases of Germany and Japan. Forest-Therapy program was used to get psychological stability, release stress and treat alcohol diseases. There was some cases that adopt the nature to clinical field actively. The clinical articles were mainly published about stress and health. Conclusions : It seems that running the constitutional program that considers different among individuals adopting Sasang constitutional medicine, utilizing Forest-Therapy Doctor through the participation of Public Oriental Medicine Doctor, and operating experience program applying Herb have sufficient possibility.

• Korean Journal of Oriental Medicine
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• v.16 no.3
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• pp.127-133
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• 2010

The purpose of this study is to develop the order communication system for Traditional Korean Medicine(TKM) which can support prescribing decisions and provide the toxicological information. The relative vulnerability of the infrastructure of TKM has made us start the study. We carried out the benchmarking for TKM charting solution firstly, and then designed the intelligent search and supporting method for prescription decisions. We developed of the medical herbs database and the web-based order communication program which can be used in medical field actually. This system supplies a various functions to oriental medical doctors such as management for prescription history, search for herb's effects, generating prescriptions, inventory management, alerting of toxicity and taboo, guideline for taking medicine, and so on. The design and implementation process has been described in this research. We expect that this system will play an important role in electronic medical record(EMR) or electronic health record(EHR) binding diagnosis and management functions.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.11 no.2
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• pp.55-65
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• 2008

This study was surveyed to analyze vegetation structure of mountainous wetlands in Chung-ju city and around area from September to November, 2006. 6 sites of total 15 potential mountainous wetlands were discriminated throughout field survey. By classification system of mountainous wetlands presented in manual of forest wetlands research, types of wetlands were classified into slant and a flat. Many sites were covered with land plants as Pueraria thunbergiana and so on. To understand vegetation structure of mountainous wetlands, Height, DBH (diameter at breast height), DI (Dominance Index), Sociability and Constancy were surveyed and Based on this result, a projection chart was drawn. As results, Salix koreensis in tree layer and Persicaria thunbergii and Impatiens textori in herb layer were surveyed as broadly distributed species. This study is mainly focused on vegetation condition of mountainous wetlands. But, it will be needed studying on classification system of mountainous wetland type and functional assessment for conservation or management of wetlands.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.13 no.1
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• pp.1-13
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• 2010

This study was accomplished to identify and analyze vegetation structure of Mountainous Wetlands in Dan-yang and around area, and surveyed from September to November, 2006. 6 sites of total 16 potential Mountainous Wetlands by GIS based wetland forecasting system (Korea National Arboretum, 2006) were identified as wetlands throughout field survey by the indicators such as hydrology, soil and vegetation. By classification system of Korea National Arboretum (2006), types of wetlands were classified into 3 slope-types and 3 flat-types. To understand vegetation structure of wetlands, height, DBH (diameter at breast height), DI (Dominance Index), sociability and constancy were surveyed and the projection diagram and charts ware drawn. As results, Salix koreensis in woody plant layer and Persicaria thunbergiiin and Juncus effusus var. decipiens in herb layer were surveyed as broadly distributed species. The wetlands of Dan-yang around area were similar to those of Chung-ju around area, but the species of plants and hydrology conditions were different. This study is mainly focused on vegetation condition of Mountainous Wetlands. But, further studies on functional assessment for management and restoration of wetlands were necessary.

• Journal of Korean Traditional Oncology
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• v.13 no.1
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• pp.43-54
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• 2008

Objectives: The purpose of this study is to suggest better directions in experimental researches about finding new drug derived from herbs in South Korea. Methods: We investigated available manuscripts on anti-lung cancer herbal extracts which is used in South Korea by using available electric library, and made diagrams. Results: Many herbs are used in treatment of lung cancer based on traditional oriental medical theory. In Korea, researches for this field have been activated since 2000. But we haven't found the substance showing remarkable anti-tumor effect on lung cancer. And many of the experiment have been designed similar way and also have similar weak points in explanation about the apoptotic mechanism. Conclusions: From this results, we have found 10 herbs, 4 pharmacopunctures and 13 herbal decoctions to be conducted experimental studies for lung cancer from 2000 to 2008 in South Korea.

• Herbal Formula Science
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• v.16 no.2
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• pp.71-90
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• 2008

東醫寶鑑(DongEuiBoGam) is considered as one of the most valuable medical books for Korean traditional medicine. Since 許浚(Heo Jun), the best physician on his day, wrote 東醫寶鑑(DongEuiBoGam), it has been not only a guidebook for basic medical studies, but also a field manual for clinicians. 東醫寶鑑(DongEuiBoGam) is a medical encyclopedia which integrated more than 81 medial classics. And its contents is well organized according to the symptoms of each disease. So today most clinics refer to 東醫寶鑑(DongEuiBoGam). But if we just read 東醫寶鑑(DongEuiBoGam) and use the prescriptions without understanding, the effect of medicine will be reduced by half. We should totally understand recipes in 東醫寶鑑(DongEuiBoGam) and be able to change the recipes according to the symptoms of each patient's disease. So finding the common traits of the recipes in 東醫寶鑑(DongEuiBoGam) is very important. In this research, the recipes of the fire part(火門) of Various Disease vol. Ⅲ(雜病篇 卷之三) are analyzed according to the traits of each herb in the recipes. And new classification of prescriptions according to the community of their traits is also suggested.

• Natural Product Sciences
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• v.26 no.1
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• pp.1-9
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• 2020

Flavonoids are mainly contained in the vegetables and medicinal herbs. Until now, over 5,000 kinds of flavonoid have been identified and their biological activities have been reported. Among them, we are interested in oroxylin A and spinosin because of their specific structures having bulky group at C-6 of ring A. Oroxylin A is contained in the Scutellaria baicalensis and exhibits cognitive enhancing activity as a GABA_A receptor antagonist, which is different from those of mainly contained in the S. baicalenis, baicalein or wogonin. Spinosin is isolated from Zizyphus jujuba var. spinosa and mainly studied as a hypnotic or anxiolytic agent because of traditional knowledge about its original herb. As far as we know, the cognitive function of spinosin was first identified by our group. In this review, we discuss how such flavonoids exert their pharmacological activities associated with cognitive function based on the receptor binding study and behavioral studies. Traditional knowledge and reverse pharmacology may be addressed in the research field of phytochemical pharmacology and useful to unveil the secret of phytochemicals.

• Journal of environmental and Sanitary engineering
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• v.6 no.2
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• pp.59-68
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• 1991

The word of stress was wsed in the field of physics as a external force from 17th century, but the meaning of this stress had chafed to the internal and exteral demand fort the human body in medical area. All the stumulants which make stress was called as j stressor. When animals get stress blucose excreted from liver to adapt for the emergent state ant some related hormone secrete convert protein and lipid to glucose for the purpose of energy supply to muscle. As a results heart rate, blood pressure, respiration rate are increased and musclse are strengthed. These physiolgical reactions ate controlled by autonomic nerve system under the control of hyothalamus in brain. Autonomic nerve system and endocrinary system are react harmoiously to stress reaction. According to the stress reaction, adrenomedullary system are stimulated, and epinephrine, morepinephrine are exceted. Author experimented the effect of the immobilizational stress to rat by analyzing the variaition of catecholamine secrction, the Na concentration and the effect of the antistresf effect by Panax Ginseng which is a traditional Korean herb medicine. The concentration of the norepinephrine, epinephrin, and dopamin in normal rat are 1 578 ng/ml, 0.365 ng/ml, and 0.731 ng/ml respectively, but in the immobilyzed stress groIn the concentration were increased to 1.915 ng.ml, 0.854 ng/ml, and 2,361 ng/ml which she the high show the higher concentration of catecholamine to stressor.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.19 no.3
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• pp.93-102
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• 2016

An invasive disturbance species has caused harm to biodiversity and ecosystem. To address the issue, identifying the characteristics of a habitat for invasive disturbance species is considered for forest management. This study analyzed a status of plant species by field survey based on belt transect method in the capital areas and established a predictive model for invasive disturbance species by logistic regression. As results of the study, the number of herb, vine, and invasive disturbance species and a canopy cover of tree would decrease from the forest edge to core areas (p<0.001). The predictive model was derived with variables of altitude, Topographic Wetness Index, distance to forest edge, and canopy cover of tree. It can be useful in estimating the presence or absence of species and predicting its spatial distribution. Further studies are needed to identify the pathway of introduction, spread, and possibility of germination for understanding the status of invasive disturbance species in more depth.