• 한국동물위생학회지
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• 제42권4호
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• pp.279-283
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• 2019

An 8-year-old castrated male Korean short hair cat was referred with chronic vomiting, diarrhea, and anorexia. The cat was diagnosed with alimentary lymphoma via fine needle aspiration. Three weeks later, he was presented again with anorexia. Hepatomegaly and hyperechoic change in the liver parenchyma were observed. Computed tomography while awake was performed and revealed hypoattenuation of the hepatic parenchyma. The cat was tentatively diagnosed with feline hepatic lipidosis secondary to alimentary lymphoma. In the feline patient with lymphoma, hepatomegaly is important to differentiate hepatic lipidosis from hepatic infiltration of lymphoma on liver. In the present case, fatty infiltration of the liver was identified via non-invasive, rapid, and convenient computed tomography examination in an awake cat with a lymphoma.

• 한국임상수의학회지
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• 제33권3호
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• pp.160-164
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• 2016

A Turkish angora cat with a one-week history of anorexia and vomiting was diagnosed with hepatic lipidosis. During hospitalization and treatment, the cat suddenly showed respiratory-related clinical signs, including coughing and dyspnea, 13 days after initial diagnosis. Due to the poor response to treatment, the patient was euthanized at the owner's request. A postmortem histopathologic examination of the cat's heart showed dilation and wall thinning of the right atrium and ventricle, with fibrofatty infiltration corresponding to an arrhythmogenic right ventricular cardiomyopathy (ARVC). This is a case report of ARVC concurrent with hepatic lipidosis in a cat; both diseases are related to disturbances in lipid metabolism.

• 대한수의학회지
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• 제48권4호
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• pp.489-492
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• 2008

An 8-year-old male mynah (Gracula spp.) was presented for depression, anorexia, and respiratory distress. The patient's diet consisted of sponge cake and yogurt alone. Physical examination revealed high body condition score (4/5), abdominal distention, and severe orthopnea. Hepatomegaly was observed on abdominal radiographs. The patient died 4 h after presentation, and severe hepatomegaly was observed at necropsy. Based on histopathological findings, the bird was definitively diagnosed with iron storage disease with concurrent hepatic lipidosis.

• 한국임상수의학회지
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• 제32권5호
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• pp.449-453
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• 2015

7년령의 불임 암컷 소말리 교잡종 고양이가 4주 동안 지속된 식욕부진, 구토, 체중감소, 무기력을 주증으로 내원하였다. 환자는 지방간으로 진단 되었으며, 3주 동안 집중치료와 더불어 비위 영양관을 통해 유동식을 공급하였다. 치료기간 중, 지방간으로 인한 임상증상은 개선 되었지만 고양이 피부유약증으로 인한 것으로 의심되는 피부병변이 왼쪽과 오른쪽 어깨 부위에서 발견되었다. 과립당치료, 레이저치료 및 외과적 피판술을 통한 집중적인 상처 치유를 실시하였으며, 그 결과 환자는 다른 임상 증상이나 피부 병변의 재발 없이 성공적으로 치료되었다. 보고된 바에 따르면, 본 증례는 간질환과 고양이 피부유약증이 동반한 환자에서 좋은 예후를 보인 첫 번째 증례이다.

• 대한수의학회지
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• 제57권2호
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• pp.127-129
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• 2017

Intercostal abdominal hernia in the 11th intercostal space was identified in a leopard cat. Although mild leukopenia was found in laboratory examinations, no remarkable abnormality was revealed in medical imaging. To investigate abdominal organs, diagnostic laparoscopy was performed after hernia repair. In laparoscopic view, closure of the herniation site and a lesion with whitish discoloration in the liver (left medial lobe) were observed. Subsequently, laparoscopic liver biopsy was performed against the affected hepatic tissue. Histologically, the sample was diagnosed as mild hepatic lipidosis. Laparoscopy is considered useful for abdominal visceral examination and liver biopsy in a leopard cat patient.

• 대한수의학회지
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• 제58권2호
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• pp.99-101
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• 2018

A 5-year-old intact female Persian cat was referred with anorexia and vomiting. Physical examination revealed icterus in the pinna, oral mucosa, and sclera. Ultrasonography revealed several findings including uniformly hyperechoic hepatic parenchyma compared to adjacent falciform fat, increased attenuation of the ultrasound beam, and poor visualization of intrahepatic vessel borders. Computed tomography revealed hypoattenuation of the hepatic parenchyma with a radiodensity value of -60 Hounsfield units. The adjacent intrahepatic vessels appeared hyperattenuated relative to the hepatic parenchyma as if the vessels were contrast-enhanced. Based on ultrasonography and computed tomography results, the cat was tentatively diagnosed as feline hepatic lipidosis.

• 한국임상수의학회지
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• 제7권1호
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• pp.381-390
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• 1990

In order to study the effects of administration of carbon tetrachloride(CCI$_4$) and 1-naphthylisothiocyanate(ANIT) on the liver of Korean black goats, some liver function tests and liver biopsy were done on 4 Korean black goats dosed with CCI$_4$(0.4m1/kg of body weight) in-traruminally and 4 Korean black goats dosed with ANIT(400mg/kg of body weight) by stomach tube. BSP Tl/2 and serum total bilirubin concentration in goats dosed with CCI$_4$ were increased gradually, reached to maximum value on 2nd and 1st day, respectively, and then began to decrease in normal range, gradually. In goats dosed with ANIT, BSP Tl/2 and serum total bilirubin concentration were increased rapidly, reached to maximum value on 0.5 and 1st day, respectively, and then returned to normal ragne, rapidly. Serum SDH, AST and GGT activities in goats dosed with CCI$_4$ were increased rapidly and reached to maximum value on 3rd, 1st and 2nd day, respectively. Thereafter, the serum enzyme activities began to decrease in normal range gradually. In goats dosed with ANIT, however, serum SDH, AST and GGT activities were not changed. The histopathologic changes in goats dosed with CCI$_4$ were lipidosis and centrilobular nee-rosis of the hepatic parenchyma. In goats dosed with ANIT, hyperplasia of bile duct epithelium was noticeable, but pathologic changes in liver parenchyma were not noticed. Conclusively, in Korean black goats dosed with CCI$_4$, main finding was necrosis of hepatic parenchyma. In Korean black goats dosed with ANIT, main finding was cholestasis.