• Title/Summary/Keyword: heat stroke

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A Study On the $Conform^{TM}$ Process of Al 1100 Alloy (Al 1100 합금의 $Conform^{TM}$ 공정에 관한 연구)

  • Kim, S.H.;Han, S.S.;Han, C.H.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2006.05a
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    • pp.329-332
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    • 2006
  • $Conform^{TM}$, a continuous extrusion forming process can produce a variety of very long extruded products such as aluminum alloyed wires, strips and profiles, hollow sectioned tubes, coated wires used in the current forming industry. This process has some advantages like as superiority of pre-heating free, availability of high extrusion ratio and continuous forming without stroke limit. But it is still difficult to analyze the realistic model of the process. In this study the analysis using two-dimensional model of $Conform^{TM}$ process together with several parametric investigations on the heat transfer are carried out by FEA code DEFORM $^{TM}2D$. In spite of simple model the results of analysis shows a good guidance to design the real process.

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An Experimental Study on Combustion Characteristics of Biodiesel Fuel in Marine Diesel Engine (선박디젤기관에서 바이오디젤연료의 연소특성에 대한 실험적 연구)

  • Cho, Sang-Gon
    • Journal of Power System Engineering
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    • v.19 no.3
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    • pp.29-35
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    • 2015
  • Environmental pollution is produced by consumption of fossil fuel, therefore alternative fuels is interested for development of new energy resources and reduction of exhaust emissions for air pollution prevention. Biofuels are produced from new vegetable oil and animal fat, may be used as fuel without change of engine structure in diesel engine. In this paper, the test results on specific fuel consumption, combustion characteristics of neat diesel oil and biodiesel blends(10 vol.% biodiesel and 20 vol.% biodiesel) were presented using four stroke, direct injection diesel engine, especially this biodiesel was produced from biodiesel fuel at our laboratory by ourselves. This study showed that specific fuel consumption is increased slightly, on the other hand cylinder pressure, rate of pressure rise, rate of heat release and soot were decreased slightly in the case of biodiesel blends than neat diesel oil.

Study on the Thermal Stress Distribution Characteristivs of the Cylinder Block of a Light Gasoline Engine (경차용 가솔린 기관 실린더 블럭의 열응력 분포 특성에 대한 연구)

  • 김병탁
    • Journal of Advanced Marine Engineering and Technology
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    • v.22 no.6
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    • pp.800-808
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    • 1998
  • In this study the thermal stress distribution and deformantion characteristics resulting from the nonuniform temperature fields of the cylinder block of a light 3-cylinder 4-stroke gasoline engine were analyzed using the 3-dimensional finite element method. The temperature distributions req-uisite for the thermoelastic behavior alalysis were obtained from the steady-state heat conduction analysis performed on the basis of experimental data. in order to examine the effect of a ceramic material the cylinder liner was replaced by the silicon nitride($Si_{3}N_{4}$) and its thermal behaviors were compared with those of the original block.

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Development of a Program for Analyzing the Characteristics of the Temperature Distribution of the LPG Engine Cylinder Block (LPG 엔진 실린더 블록의 온도 분포 특성 해석을 위한 프로그램 개발)

  • Son, Byung Jin;You, Chin Sok;Kim, Chang Hun
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.22 no.12
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    • pp.1746-1754
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    • 1998
  • A computer program has been developed to predict the heat transfer characteristics and the temperature distribution in the cylinder block of a 4-cylinder, 4-stroke engine. The finete element method is employed to handle the complex geometries associated with the practical cylinder block. The hexahedron finite element is used for a mesh generation of three-dimensional domain. The present numerical procedure has been validated with the measured temperature at several locations of cylinder block. The heat transfer characteristics of engine cylinder block is systematically analyzed for various engine speeds and loading conditions.

S100ß, Matrix Metalloproteinase-9, D-dimer, and Heat Shock Protein 70 Are Serologic Biomarkers of Acute Cerebral Infarction in a Mouse Model of Transient MCA Occlusion

  • Choi, Jong-Il;Ha, Sung-Kon;Lim, Dong-Jun;Kim, Sang-Dae;Kim, Se-Hoon
    • Journal of Korean Neurosurgical Society
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    • v.61 no.5
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    • pp.548-558
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    • 2018
  • Objective : Diagnosing acute cerebral infarction is crucial in determining prognosis of stroke patients. Although many serologic tests for prompt diagnosis are available, the clinical application of serologic tests is currently limited. We investigated whether $S100{\beta}$, matrix metalloproteinase-9 (MMP-9), D-dimer, and heat shock protein 70 (HSP70) can be used as biomarkers for acute cerebral infarction. Methods : Focal cerebral ischemia was induced using the modified intraluminal filament technique. Mice were randomly assigned to 30-minute occlusion (n=10), 60-minute occlusion (n=10), or sham (n=5) groups. Four hours later, neurological deficits were evaluated and blood samples were obtained. Infarction volumes were calculated and plasma $S100{\beta}$, MMP-9, D-dimer, and HSP70 levels were measured using enzyme-linked immunosorbent assay. Results : The average infarction volume was $12.32{\pm}2.31mm^3$ and $46.9{\pm}7.43mm^3$ in the 30- and 60-minute groups, respectively. The mean neurological score in the two ischemic groups was $1.6{\pm}0.55$ and $3.2{\pm}0.70$, respectively. $S100{\beta}$, MMP-9, and HSP70 expressions significantly increased after 4 hours of ischemia (p=0.001). Furthermore, $S100{\beta}$ and MMP-9 expressions correlated with infarction volumes (p<0.001) and neurological deficits (p<0.001). There was no significant difference in D-dimer expression between groups (p=0.843). The area under the receiver operating characteristic curve (AUC) showed high sensitivity and specificity for MMP-9, HSP70 (AUC=1), and $S100{\beta}$ (AUC=0.98). Conclusion : $S100{\beta}$, MMP-9, and HSP70 can complement current diagnostic tools to assess cerebral infarction, suggesting their use as potential biomarkers for acute cerebral infarction.

Studies on application of Radix Puerariae main blended Prescription from Donguibogam (동의보감(東醫寶鑑) 중(中) 갈근(葛根)이 주약(主藥)으로 배오(配伍)된 처방(處方)의 방제학적(方劑學的) 고찰(考察))

  • Cho Nae-Jin;Yun Young-Gab
    • Herbal Formula Science
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    • v.11 no.1
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    • pp.19-36
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    • 2003
  • Through investigation on prescriptions from Dongeuibogam with Radix Puerariae as an ingredient, the following conclusions were reached. The 59 prescriptions with Radix Puerariae as an ingredient are mentioned from chapter of Pediatrics to chapter of Intestinal Convulsions. And 85% of those appears from chapter of Pediatrics to chapter of coughs. Prescriptions with Radix Puerariae as the main ingredient are used for skin diseases, cold, epidemics, abscess, diabetes, stroke, feverish diseases, intestinal diseases, weakness and cough. The dosage of Radix Puerariae varies from 0.875g to 11.25g. 3.75g was the most frequently used dosage which accounts 44%. And those with small dosage of 0.875 to 1.125g were for use on infants or pregnant women. The grounding pathology used for prescriptions with Radix Puerariae as an ingredient appeared to be mostly the pathology related to the Six External Qi. Among this, wind with cold(風寒), wind, cold with heat and humidity(風寒署濕), catching cold(傷寒), successively catching cold(兩感傷寒), cold of the Yangmyung and heat clogging(陽明傷寒火鬱), abnormal weather(時令不正) are the majority. Through the prescriptions with Radix Puerariae as an ingredient, it could be concluded Radix Puerariae that has various functions such as sweating and removing rash(發表透疹), exhalation and curing muscular ache(發散解肌), producing body fluid and ceasing thirst(生津止渴), opening abscess and healing the scar(托瘡生肌), removal of fever(解熱), resolving hangover(醒酒). Seungmagalguntang(升麻葛根湯) is used as the base prescription the most, and various prescriptions and herbs are combined according to the case.

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A Study on Application of Gypsum Main Blended Prescription From Dongeuibogam (동의보감(東醫寶鑑) 중 석고(石膏)가 주약(主藥)으로 배오(配伍)된 방제(方劑)의 활용(活用)에 대한 고찰(考察))

  • Oh, Whang;Lee, Jang-Cheon
    • Herbal Formula Science
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    • v.15 no.1
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    • pp.1-19
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    • 2007
  • This study was investigated to make sure the range of Gypsum treatment, the nature of disease, the pathology and the dosage of it in Dongeuybogam. The following conclusions were reached through investigations on the prescriptions that use Gypsum as a key ingredient. The Gypsum blended prescriptions are utilized in 23 fields of treatment such as cold, head. ect. Prescriptions that use Gypsum as the main ingredient are used commonly in the treatment of cold, head disease, fever, skin disease, diabetes, stroke, ophthalmic disease, jaundice, ENT disease and dental disease. The Gypsum is used for nature of disease which of cold, heat(fever), summer heat, phlegm, malfunction of liver, malfunction of liver and kidney, heat of stomach, malfunction of spleen and fever of stomach. The clinical dosage of Gypsum has ranged at a wide variety of amount from 1.6g to 16g per dose with 4g ${\sim}$ 8g being the typical dose for most treatment. The Gypsum is applied as a fundamental prescription with several herb remedies for the pathology.

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COMBUSTION STABILITY OF DIESEL-FUELED HCCI

  • Shi, L.;Deng, K.;Cui, Y.
    • International Journal of Automotive Technology
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    • v.8 no.4
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    • pp.395-402
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    • 2007
  • Homogeneous Charge Compression Ignition (HCCI) shows great potential for low $NO_x$ emission but is hampered by the problem of no direct method to control the combustion process. Therefore, HCCI combustion becomes unstable easily, especially at lower and higher engine load. This paper presents a method to achieve diesel-fueled HCCI combustion, which involves directly injecting diesel fuel into the cylinder before the piston arrives at top dead center in the exhaust stroke and adjusting the valve overlap duration to trap more high temperature residual gas in the cylinder. The combustion stability of diesel-fueled HCCI combustion and the effects of engine load, speed, and valve overlap on it are the main points of investigation. The results show that: diesel-fueled HCCI combustion has two-stage heat release rate (low temperature and high temperature heat release) and very low $NO_x$ emission, combustion stability of the HCCI engine is worse at lower load because of misfire and at higher load because of knock, the increase in engine speed aids combustion stability at lower load because the heat loss is reduced, and increasing negative valve overlap can increase in-cylinder temperature which aids combustion stability at lower load but harms it at higher load.

Comparative study on Hsp25 expression in Mongolian gerbil and mouse cerebellum

  • Lee, Heang-Yeon;Kim, Seong-Hwan;Lee, Jae-Bong;Shin, Chang-Ho
    • Korean Journal of Veterinary Service
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    • v.29 no.4
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    • pp.469-482
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    • 2006
  • The term 'heat shock protein (Hsps)' was derived from the fact that these proteins were initially discovered to be induced by hyperthermic conditions. In response to a range of stressful stimuli, including hyperthermia, immobilization, UV radiation, amino acid analogues, arsenite, various chemicals, and drugs the mammalian brain demonstrates a rapid and intense induction of the heat shock protein. Moreover, Hsps were expressed on the various pathological conditions including trauma, focal or global ischemia, hypoxia, infarction, infections, starvation, and anoxia. Especially, Hsp25 has a protective activity, facilitated by the ability of the protein to decrease the intracellular levels of reactive oxygen species (ROS) as well as its chaperone activity, which favors the degradation of oxidized proteins. Recently, it has clearly demonstrated that Hsp25 is constitutively expressed in the adult mouse cerebellum by parasagittal bands of purkinje cells in three distinct regions, the central zone (lobule VI-VII) and nodular zone (lobule IX-X), and paraflocculus. The Mongolian gerbil has been introduced into stroke study model because of its unique brain vasculature. There are no significant connections between the basilarvertebral system and the carotid system. This anatomy feature renders the mongolian gerbil susceptible to forebrain ischemia-induced seizure. The present study is designed to examine the pattern of Hsp25 expression in the cerebellum of this animal in comparison with that in mouse.

Short Tenn Reactions to Acupuncture Treatment and Adverse Events Following Acupuncture in Korea a Cross-sectional Survey of Patient Reports (침치료 직 후 자가 설문지를 이용한 침반응(針感)과 부작용에 대한 단면적 연구)

  • Park, Seong-Uk;Jung, Woo-Sang;Moon, Sang-Kwan;Ko, Chang-Nam;Cho, Ki-Ho;Kim, Young-Suk;Bae, Hyung-Sup;Park, Jung-Mi
    • The Journal of Korean Medicine
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    • v.28 no.2 s.70
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    • pp.66-79
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    • 2007
  • Objectives : To explore the type and frequency of short term reactions, de Qi associated with acupuncture treatment and to determine the incidence of adverse events following acupuncture in Korea. Subjects and methods : This study is a retrospective and cross-sectional survey of patient reports. 1095 subjects, 585 of out-patients of the Oriental Medicine of Stroke & Neurological Disorders Center, East-West NEO Medical Center of Kyunghee University and 510 of out-patients of the Department of Cardiovascular & Neurologic Diseases (Stoke Center), Hospital of Oriental Medicine, Kyunghee Medical Center, from June through November of 2006, who had acupuncture, gave informed consent and completed one survey form. On this form, patients were asked to report short term acupuncture reactions, de Qi, patient satisfaction measurement (using VAS), and adverse events relating to acupuncture treatment. The acupuncturists of this study are Korean Medicine Doctors (KMD) who had worked as practitioners for 3-30 years or more. Results : The average age of the 1095 subjects was 58 years old. Positive short term acupuncture reactions after treatment were reported by 878 (80.2%), negative short term acupuncture reactions by 75 (6.8%) and no reactions were reported by 142 (13.0%). The most common positive short term acupuncture reactions were feeling 'relaxed', 472 (43.1%), followed by feeling 'less pain' 90 (8.2%), 'energized' 16 ( 1.5%), 'tingling' 16 (1.5%), 'heat feeling or Cold feeling' 10 (0.9%), and others 274 (25.0%), respectively. Negative short term acupuncture reactions were feeling 'pain' 37 (3.4%), tiredness 24 (2.2%), dizziness 9 (0.8%), and others 5 (0.2%), respectively. Traditionally described needling sensations of de Qi refer to a patient's response to distention, pulling, soreness, heaviness, numbness. 39.7% of subjects reported de Qi during needling, experiencing 'distention' 333 (30.4%), 'soreness' 52 (4.7%), 'pulling' 22 (2.0%), 'heaviness' 18 (1.6%), and 'numbness' 10 (0.9%) respectively. Positive short term acupuncture reactions and de Qi rate were the highest in the less than 40 years group (83/96 86.5%, 50/96 52.1%). No acupuncture reactions were highly seen in the over 70 years old group (31/187, 16.6%). Patient satisfaction level using VAS was a comparatively high $72.9{\pm}19.9$. Adverse events were only bleeding in 92 (8.4%) of the total subjects. High sensitive acupoints were 95 points as GV26 (54 times), LI4 (54 times), ST36 (53 times), GB20 (37 times), HT8(34 times), LV3 (29 times), SI3 (29 times), and LI11 (27 times) in order. Main impressions were stroke patients 430 (16.9%), headache 185 (16.9%), hypertension 97 (8.9%), and dizziness 85 (7.8%). Conclusions : Although 8 different Korean Medicine Doctors participated in this research, we obtained similar results from each. There were no significantly different results between the two hospitals. Short term acupuncture reactions and de Qi were most related to age. Except for bleeding there were no adverse events relating to acupuncture treatment in this study. We consider acupuncture treatment as very safe depending on practitioners. Positive short term acupuncture reactions after treatment were 12 times higher than negative short term acupuncture reactions. Subjects were comparatively satisfied with acupuncture treatment.

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