• KSBB Journal
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• v.16 no.6
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• pp.626-631
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• 2001

Lactobacilli have been considered to play important roles in the health of human vagina. They secrete inhibitory substances to prevent vaginal infection by pathogenic organisms. In a previous study, we have isolated several lactobacilli from Korean woman and one of them (KLB46) was selected and indentified as Lactobacillu crispatus which showed high antimicrobial activity. In this study. cold adaptation prior to subsequent stresses exposure was examined whether L. crispatus KLB46 maintain the viability better than the non-adapted calls under stresses. For pharmaceutical formulation, the lyophilization process is required where stresses such as freezing/thawing and dehydration are routinely applied. Formulated L. crispatus KLB46 can be used for ecological treatment of bacterial vaginosis. The response of cold-adapted cells to other environmental stresses such as acid, heat, ethanol, NaCl, and H$_2$O$_2$ was also examined. The results showed that cold-adapted cells maintained higher survival rate compared with the non-adapted cells (freezing-thawing. 3-folds; dehydration: 3-folds; acid, 3-folds; heat, 10-folds). However, we did net observe any positive effect of cold adaptation on other stresses such as ethanol, NaCl and H$_2$O$_2$. When chloramphenicol was added during cold adaptation, adaptation effect was abolished. This confirms that de novo protein synthesis is necessary during the adaptation process. Moreover, we have identified cold shock protein homolog that codes for a major cold shock protein by PCR amplification using degenerate primers.

• The Korean Journal of Physiology and Pharmacology
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• v.11 no.6
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• pp.233-237
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• 2007

Tropical natives (TROP) are capable of tolerating tropical heat because of their long-term adaptation to tropical environments. When exposed to heat stress, these natives tend to respond with lower sweat output, which is generally thought to be the result of heat acclimatization. The main objective of this study was to clarify central mechanisms inherent to suppressed thermal sweating in tropical natives (Malaysians) by comparing their sweating responses to those of temperate native (TEMP) (Koreans). This experiment was conducted in a thermoneutral climatic chamber ($24{\pm}0.5^{\circ}C,\;40{\pm}3%$ relative humidity). Heat loads were applied to each subject by the immersion of their lower legs in a hot water bath ($43^{\circ}C$ for 30 min). Sweat onset-time and sweat volume were compared between TROP and TEMP. The sweat onset-times on four selected points on the body ranged from 10.25 to 13.47 min in TEMP subjects, and from 16.24 to 17.83 min in TROP subjects (p<0.001). The local sweat volumes at the same sites ranged from 4.30 to $9.74 mg/cm^2$ in TEMP subjects, and from between 1.80 to $4.40mg/cm^2$ in TROP subjects (p<0.001). These results demonstrated a significant difference between TROP and TEMP subjects with regard to the manner in which they regulate their body temperatures when exposed to heat loads, and verified that long-term thermal adaptation blunts sweating sensitivities.

• Safety and Health at Work
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• v.11 no.1
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• pp.1-9
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• 2020

Background: As the impact of climate change intensifies, exposure to heat stress will grow, leading to a loss of work capacity for vulnerable occupations and affecting individual labor decisions. This study estimates the future work capacity under the Representative Concentration Pathways 8.5 scenario and discusses its regional impacts on the occupational structure in the Republic of Korea. Methods: The data utilized for this study constitute the local wet bulb globe temperature from the Korea Meteorological Administration and information from the Korean Working Condition Survey from the Occupational Safety and Health Research Institute of Korea. Using these data, we classify the occupations vulnerable to heat stress and estimate future changes in work capacity at the local scale, considering the occupational structure. We then identify the spatial cluster of diminishing work capacity using exploratory spatial data analysis. Results: Our findings indicate that 52 occupations are at risk of heat stress, including machine operators and elementary laborers working in the construction, welding, metal, and mining industries. Moreover, spatial clusters with diminished work capacity appear in southwest Korea. Conclusion: Although previous studies investigated the work capacity associated with heat stress in terms of climatic impact, this study quantifies the local impacts due to the global risk of climate change. The results suggest the need for mainstreaming an adaptation policy related to work capacity in regional development strategies.

• KIEAE Journal
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• v.12 no.4
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• pp.13-19
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• 2012

The Earth's surface temperature still continues to rise, and extreme weather phenomena such as heat waves, drought, and precipitation have been repeated every year. It is reported that international communities attribute the main cause of the Earth's surface temperature rise to the excessive use of the fossil energy. Recently, the damage caused by climate change is getting worse, and the place where we live is suffering the most. Cities have been continuously growing not only meeting the basic functions of human habitation, work and leisure but also being places for various economic and social activities. But Cities, the victims of climate change, have grown only considering human needs and convenience rather than predicting their physical and ecological systems(Albedo effects, urban microclimate, resources and energy of the circulatory system, etc). In other words, the cities offer the cause of the problems of climate change, and even worsen the extreme weather phenomena without coping with them. Therefore, it is urgent priorities to protect the climate, to prevent the causes of the extreme weather phenomena and to enhance the adaptive capacity for the worse weather events. This study is to derive the concept for adapting to these climate changes which can make cities escape from exposure to these climate change impacts and make themselves safer places to live. And it analyzes some European cities and present developing models to implement planning methods. In this study, the concept of the climate adaptive cities will be suggested to prepare the adaptation measures for urban planners, and climate change adaptation models will be presented by analyzing some preliminary cases.

• Asian-Australasian Journal of Animal Sciences
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• v.20 no.5
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• pp.742-747
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• 2007

In order to investigate the mechanism of adaptation to long-term heat stress, six female buffalo calves of about 7 to 8 months age, were exposed to the cool-comfort environment (THI 65) for 21 days to obtain normal values of blood acid-base. An adaptive response of acid-base regulation was determined to long term (21 days) exposure of buffalo calves to hot-dry (THI 80) and hot-humid (THI 84) conditions. Higher rectal temperature and respiratory rate was recorded under hot-humid exposure compared to hot-dry. Significant reduction in the rectal temperature and respiratory rate on day 21 of hot-dry exposure indicated early thermal adaptation compared to hot-humid. Decreasing rectal temperature and respiratory rate from day 1 to 21 was associated with concurrent decrease in blood pH and pCO2. Increased plasma chloride concentration with low base excess in blood and in extracellular fluid suggested compensatory response to respiratory alkalosis. Reduced fractional excretion of sodium with increased fractional excretion of potassium and urine flow rate indicated renal adaptive response to heat stress.

• Journal of Korean Society of Water and Wastewater
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• v.32 no.6
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• pp.517-526
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• 2018

Climate adaptation strategies for water utilities including 16 water treatment plants(WTPs) in Jeju were investigated. Drought, heat wave, and heavy rain were among the most significant climate factors affecting water utilities in Jeju. Heat wave increases water temperature, which in turn increases the concentration of algae, color, and odor materials. Some adaption strategies for the heat wave can be strengthening water monitoring and introducing advanced water treatments. Heavy rain increases raw water turbidity in surface water. The 7 WTPs that take raw water from streams or springs had a maximum turbidity of less than 50 NTU under heavy rain. However, due to concerns of turbidity spike in treated water, some WTPs discontinued intaking raw water when raw water turbidity increased more than 2 NTU. They instead received treated water from other WTPs which took groundwater for water supply. This happens because of the low skills of employees. Thus, there needs to be an increase in operator competency and upgrade of water facilities for the adaption of heavy rain. To improve adaption for the drought, there should be an increase in the capacity of intake facilities of surface water as well as a decrease in water loss. In addition, water consumption per person should be decreased.

• Proceedings of the SAREK Conference
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• 2006.06a
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• pp.838-846
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• 2006

The purpose of this study to develop the air-conditioning system that adopts adaptive model as an indoor climate control logic for energy saving. The adaptive model using the ability of human thermal adaptation could be expected to alleviate the indoor set-point temperature compared with the past heat-balance model. Especially, in case of hybrid air-conditioning system coupled with natural ventilation and heating/cooling system, the adaptive model can be describe the thermal comfort of inhabitant who stay at hybrid system controlled buildings with accuracy. In this paper, the concept of adaptive model will be described and the results of a continuous measurement on the actual thermal experiences and behaviors of thermal adaptation for office worker will be reported.

• Journal of Climate Change Research
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• v.5 no.3
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• pp.257-266
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• 2014

This study aims to understand abnormal climate caused by impacts of climate change and to suggest the direction of urban planning focusing on adaptation to climate change. The study consists of theory consideration and case study(Chicago, Philadelphia, Seattle). As a result, the main impacts of climate change faced by urban areas are heat wave, precipitation, and drought. To prevent these impacts, it is important to prepare methods of urban planning as followings: planning for land use, park and green considering the climate patterns, establishing and managing water resources systems similar to the nature, securing renewable energy resources, and transportation facilities and exterior space with proof against climate. It is especially necessary to introduce infrastructures related to storm water, green roof, shading tree planting, green space, and permeable pavement. Finally, in order to realize urban planning for adaptation to climate change, it is needed to make the detailed and specific goal and strategy for the climate change adaptation plan and to extend the scope from the goals to an action plan, a detailed plan, and a design guideline.

• Journal of Oriental Medical Thermology
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• v.4 no.1
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• pp.54-60
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• 2005

Object: A study on the changes of superficial temperature as the ambient temperature varies. Method: After performing research on the physiologic mechanism of heat loss from skin, heat transfer to skin and heat productions of body, the conclusions would be drawn from experiments on temperature changes in every parts of the body as ambient temperature varies . Result and conclusion: Superficial temperature is in equilibrium with ambient temperature after a certain period. Part of the body with big change in superficial temperature tends to have slower temperature change and longer time for adaptation than the part with small change in superficial temperature. The temperature difference between left and right side of the body needs no attention. If adequate adaptation time, a short-period living supervision prior to measurements and appropriate indoor environment management are provided, meaningful conclusion would be attained for infrared thermal diagnosis.

• Journal of Animal Science and Technology
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• v.63 no.2
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• pp.319-331
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• 2021

Heat stress (HS) causes adverse impacts on pig production and health. A potential biomarker of HS is required to predict its occurrence and thereby better manage pigs under HS. Information about the saliva metabolome in heat-stressed pigs is limited. Therefore, this study was aimed to investigate the effects of acute HS on the saliva metabolome and identify metabolites that could be used as potential biomarkers. Growing pigs (n = 6, 3 boars, and 3 gilts) were raised in a thermal neutral (TN; 25℃) environment for a 5-d adaptation period (CON). After adaptation, the pigs were first exposed to HS (30℃; HS30) and then exposed to higher HS (33℃; HS33) for 24 h. Saliva was collected after adaptation, first HS, and second HS, respectively, for metabolomic analysis using 1H-nuclear magnetic resonance spectroscopy. Four metabolites had significantly variable importance in the projection (VIP > 1; p < 0.05) different levels in TN compared to HS groups from all genders (boars and gilts). However, sex-specific characteristics affected metabolites (glutamate and leucine) by showing the opposite results, indicating that HS was less severe in females than in males. A decrease in creatine levels in males and an increase in creatine phosphate levels in females would have contributed to a protective effect from protein degradation by muscle damage. The results showed that HS led to an alteration in metabolites related to energy and protein. Protection from muscle damage may be attributed to the alteration in protein-related metabolites. However, energy-related metabolites showed opposing results according to sex-specific characteristics, such as sex hormone levels and subcutaneous fat layer. This study had shown that saliva samples could be used as a noninvasive method to evaluate heat-stressed pigs. And the results in this study could be contributed to the development of a diagnostic tool as a noninvasive biomarker for managing heat-stressed pigs.