• Proceedings of the KOSOMBE Conference
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• v.1997 no.11
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• pp.533-536
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• 1997

In this paper, we visualized 3-dimensional volume of heart using volume method by thresholding in EBT slices data. Volume rendering is the method that acquire the color by casting a pixel ray to volume data. The gray level of heart region is so high that we decide heart region by thresholding method. When a pixel ray is cast to volume data, the region that is higher than threshold value becomes heart region. We effectively rendered the heart volume and showed the 3-dimensional heart volume.

• Proceedings of the Korea Society for Simulation Conference
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• 2004.05a
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• pp.109-117
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• 2004

In this paper, we consider the aortic sinus baroreceptor, which is the most representative baroreceptor sensing the variance of pressure in the cardiovascular system, and propose heart activity control model to observe the effect of delay time in heart period and stroke volume under the regulation of baroreflex in the aortic sinus. The proposed heart activity baroreflex regulation model contains electric circuit sub-model. We constituted the time delay sub-model to observe sensitivity of heart activity baroreflex regulation model by using the variable value to represent the control signal transmission time from the output of baroreflex regulation model to efferent nerve through central nervous system. The simulation object of this model is to observe variability of the cardiovascular system by variable value in time delay sub-model. As simulation results, we observe three patterns of the cardiovascular system variability by the time delay, First, if the time delay over 2.5 second, aortic pressure and stroke volume and heart rate is observed nonperiodically and observed. Finally, if time delay under 0.1 second, then heart rate and aortic pressure-heart rate trajectory is maintained in stable state.

• The Journal of Korean Society for Radiation Therapy
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• v.25 no.2
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• pp.187-192
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• 2013

Purpose: We investigate the results of changed heart volume and heart dose in the left breast cancer patients while considering the movements of respiration. Materials and Methods: During the months of March and May in 2012, we designated the 10 patients who had tangential irradiation with left breast cancer in the department of radiation Oncology. With acquired images of free breathing pattern through 3D and 4D CT, we had planed enough treatment filed for covered up the whole left breast. It compares the results of the exposed dose and the volume of heart by DVH (Dose Volume histogram). Although total dose was 50.4 Gy (1.8 Gy/28 fraction), reirradiated 9 Gy (1.8 Gy/5 Fraction) with PTV (Planning Target Volume) if necessary. Results: It compares the results of heart volume and heart dose with the free breathing in 3D CT and 4D CT. It represents the maximum difference volume of heart is 40.5%. In addition, it indicated the difference volume of maximum and minimum, average are 8.8% and 27.9%, 37.4% in total absorbed dose of heart. Conclusion: In case of tangential irradiation (opposite beam) in left breast cancer patients, it is necessary to consider the changed heart volume by the respiration of patient and the heartbeat of patient.

• Journal of Chest Surgery
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• v.38 no.12 s.257
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• pp.863-865
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• 2005

We experienced tracheobronchial stenosis caused by malrotation of the heart in a 3-year-old girl. Malrotation of the heart is induced by the decreased right lung volume, which was the result of right lung hypoplasia and herniation of the left thoracic cavity. We corrected the right lung volume and location of the heart to treat tracheobronchial stenosis.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.33 no.5
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• pp.511-517
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• 2007

Purpose: The aim of this study is to determine whether a difference in the amount of bone graft material is needed between edentulous patients and dentulous patients and to calculate the amount of augmentation for a sinus lift procedure. Methods: 19 patients(20 sinuses) were included to measure maxillary sinus volume. Facial CT scanning was performed using MX 8000 IDT CT devices(Philips, USA). And it was used for IDLvm(The IDL Virtual Machine) 6.0, CT Volume Analyzer Ver 2.3 program to measure maxillary sinus volumes Results: At edentulous patients, volumes(mean${\pm}SD$) of the inferior portion of the sinuses were $0.56{\pm}0.13cm^3$(5mm height), $2.35{\pm}0.57cm^3$(10mm height), $4.85{\pm}1.10cm^3$(15mm height). At dentulous patients, volumes(mean${\pm}SD$) of the inferior portion of the sinuses were $0.41{\pm}0.18cm^3$(5mm height), $1.76{\pm}0.42cm^3$(10mm height), $3.80{\pm}0.84cm^3$ (15mm height). A significant correlation was found between augmentation height(5mm, 10mm, 15mm) and the calculated sinus volume.(p=0.027, p=0.018, p=0.044) Conclusions: A significant correlation was found between augmentation height(5mm, 10mm, 15mm) and the calculated sinus volume. Detailed preoperative knowledge of sinus lift augmentation volume is helpful in determining the appropriate amount of the bone graft material.

• Journal of Chest Surgery
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• v.49 no.sup1
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• pp.20-27
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• 2016

Background: This study analyzed the association between the volume of heart surgeries and treatment outcomes for hospitals in the last five years. Methods: Hospitals that perform heart surgeries were chosen throughout Korea as subjects using from the Health Insurance Review and Assessment Service. The treatment outcome of the heart surgeries was defined as the mortality within 30 postoperative days, while the annual volume of the surgeries was categorized. Logistic regression was used as the statistical analysis method, and the impacts of the variables on the heart surgery treatment outcomes were then analyzed. Results: The chance of death of patients who received surgery in a hospital that performed 50 or more surgeries annually was noticeably lower than patients receiving operations from hospitals that performed fewer than 50 surgeries annually, indicating that the chance of death decreases as the annual volume of heart surgeries in the hospital increases. In particular, the mortality rate in hospitals that performed more than 200 surgeries annually was less than half of that in hospitals that performed 49 or fewer surgeries annually. Conclusion: These results indicate that accumulation of a certain level of heart surgery experience is critical in improving or maintaining the quality of heart surgeries. In order to improve the treatment outcomes of small hospitals, a support policy must be implemented that allows for cooperation with experienced professionals.

• Journal of the Korean Mathematical Society
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• v.43 no.4
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• pp.885-897
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• 2006

A new mathematical model of pumping heart coupled to lumped compartments of blood circulation is presented. This lumped pulsatile cardiovascular model consists of eight compartments of the body that include pumping heart, the systemic circulation, and the pulmonary circulation. The governing equations for the pressure and volume in each vascular compartment are derived from the following equations: Ohm's law, conservation of volume, and the definition of compliances. The pumping heart is modeled by the time-dependent linear curves of compliances in the heart. We show that the numerical results in normal case are in agreement with corresponding data found in the literature. We extend the developed lumped model of circulation in normal case into a specific model for arrhythmia. These models provide valuable tools in examining and understanding cardiovascular diseases.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.05
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• pp.161-162
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• 1997

It is very useful to perform the surgery simulation before implanting TAH(Total Artificial Heart} in a patient. The space of chest and the shape of vessels are different from patient to patient. So, It is desirable to customize a TAH design to the anatomy structure of a patient. Several studies are performed to visualize and explain the 3D structure of heart. These studies are performed using 2-dimensional ref or mated images and simple measurement. Anatomy structure of a human heart is not so simple. It is 4dimensional structure ; 3-dimensional plus time, heart beating. 3-dimensional reconstruction schemes of medical images developed for about 10 years are usually categorized into two types of rendering technique ; surface rendering and volume rendering. Volume rendering is preferable in medical image processing field because this technique can be applied without considering the complexity of geometry and change of field of interest. The usable space in the chest of patient can be measured by 3D volume matching of patient trunk and TAH model. This space changes with time. In this research we have developed the 4-dimensional volume match program of patient and TAH model. 3-dimensional rendered set of volumes along time were used to simulate TAH fitting trial. The quantitative measurement from this simulation could be applied to customize TAH design.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.05
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• pp.165-170
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• 1997

In this paper, we consider the aortic sinus baroreceptor, which is the most representative baroreceptors sensing the variance of pressure in the cardiovascular system(CVS), and propose heart activity control model to observe the effect of delay time in heart period and stroke volume under the regulation of baroreflex in arotic sinus. The proposed heart activity baroreflex regulation model contains CVS electric circuit sub-model, baroreflex regulation sub-model and time delay sub-model. In these models, applied electric circuit sub-model is researched by B.C.Choi and the baroreflex regulation sub-model transforms the input, the arotic pressure of CVS electric circuit sub-model, to outputs, heart period and stroke volume by mathematical nonlinear feedback. We constituted the time delay sub-model to observe sensitivity of heart activity baroreflex regulation model by using the variable value to represent the control signal transmission time from the output of baroreflex regulation model to efferent nerve through central nervous system. The simulation object of this model is to observe variability of the CVS by variable value in time delay sub-model. As simulation results, we observe three patterns of CVS variability by the time delay. First, if the time delay is over 2.5 sec, arotic pressure, stroke volume and heart rate is observed nonperiodically and irregularly. Second, if the time delay is from between 0.1 sec and 0.25 sec, the regular oscillation is observed. Finally, if time delay is under 0.1 sec, then heart rate and arotic pressure-heart rate trajectory is maintained in stable state.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.11
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• pp.4727-4732
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• 2014

Background: Breast cancers are becoming more frequently diagnosed at early stages with improved long term outcomes. Late normal tissue complications induced by radiotherapy must be avoided with new breast radiotherapy techniques being developed. The aim of the study was to compare dosimetric parameters of planning target volume (PTV) and organs at risk between conformal (CRT) and intensity-modulated radiation therapy (IMRT) after breast-conserving surgery. Materials and Methods: A total of 20 patients with early stage left breast cancer received adjuvant radiotherapy after conservative surgery, 10 by 3D-CRT and 10 by IMRT, with a dose of 50 Gy in 25 sessions. Plans were compared according to dose-volume histogram analyses in terms of PTV homogeneity and conformity indices as well as organs at risk dose and volume parameters. Results: The HI and CI of PTV showed no difference between 3D-CRT and IMRT, V95 gave 9.8% coverage for 3D-CRT versus 99% for IMRT, V107 volumes were recorded 11% and 1.3%, respectively. Tangential beam IMRT increased volume of ipsilateral lung V5 average of 90%, ipsilateral V20 lung volume was 13%, 19% with IMRT and 3D-CRT respectively. Patients treated with IMRT, heart volume encompassed by 60% isodose (30 Gy) reduced by average 42% (4% versus 7% with 3D-CRT), mean heart dose by average 35% (495cGy versus 1400 cGy with 3D-CRT). In IMRT minimal heart dose average is 356 cGy versus 90cGy in 3D-CRT. Conclusions: IMRT reduces irradiated volumes of heart and ipsilateral lung in high-dose areas but increases irradiated volumes in low-dose areas in breast cancer patients treated on the left side.