• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2001년도 추계학술대회 논문집
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• pp.91-95
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• 2001

In this study, we estimated the behavior of the diversity of physiological responses under varied physical environmental factors by measuring variations of heart rate variability (HRV), an index of activity of cardiac autonomic control. Seven healthy young male adults consented and participated in the study. The environmental conditions consisted of thermal, lighting, and acoustic conditions. Two components of HRV were measured. one was the low frequency (LF) component of HRV, which provided a quantitative index of the sympathetic and parasympathetic (vagal) activities controlling the heart rate (HR). The other component measured was the high frequency (HF) component, which provided an index of the vagal tone. The percent contribution of physical environmental factors to the variations in HRV indices were calculated by ANOVA. The contribution of physical environmental factors to the variations in HR was higher than the contribution of HF and LF. However, the contribution of these factors was lower than the contribution related with individual difference in all indices. This result showed that the individual diversity of physiological responses is not a negligible quantity.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2006년도 춘계학술대회 논문집
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• pp.641-642
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• 2006

The purpose of this work is to investigate the effect of work load on heart rate variability (HRV) which is widely used marker of the autonomic nervous system activity. Average heart rate, rating of perceived exertion, and the power spectrum of heart rate variability were investigated in seven healthy males during exercise at various work loads. The subjects were divided into two groups according to the average heart rate during exercise, group 1 with lower heart rate and group 2 with higher heart rate. HF component showed decrease followed by increase with workload. Accordingly, the LF/HF ratio showed increase followed by decrease with workload. The peak in LF/HF ratio of group 1 was at the lower workload than that of group 2.

• 대한한의진단학회지
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• 제15권3호
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• pp.245-260
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• 2011

Objectives: The aim of this experiment is to know the effect of Mountain Cultivated Ginseng Pharmacopuncture on Heart Rate Variability (HRV), Pulse wave velocity (PWV) in Middle Aged Women. Methods: We investigated on 40 women of breast cancer patients. First, we measured their Heart Rate Variability(HRV), Pulse wave velocity (PWV) and then Mountain Cultivated Ginseng Pharmacopuncture $20m{\ell}$ were injected on them. After 30 minutes, we measured Heart Rate Variability(HRV), Pulse wave velocity(PWV) again. As a result, method of non-equivalent control group non-synchronized design were used for evaluation. Results: In HRV, Mean HRV is significantly decreased from 69.15 to 63.34 after injection. Mean RR is significantly increased from 877.20 to 962.10 after injection. SDNN is significantly increased from 32.56 to 41.34 after injection. PNN50 is significantly decreased after injection. RNSSD, SDSD, TP, VLF is significantly increased after injection. Stress Resistance ability is significantly increased from 37.55 to 44.60 after injection. And In PWV, E-R, E-L, H-R, H-L is significantly decreased after injection. Conclusions: Effect of Mountain Cultivated Ginseng Pharmacopuncture on Heart Rate Variability (HRV) increased adaptability of autonomic nervous system and on Pulse wave velocity (PWV) decreased arterial stiffness.

• 한국건강관리협회지
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• 제4권1호
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• pp.28-38
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• 2006

Background : Phentermine classified by "sympathomimmetic amie", is a stimulant of sympatheic tone But there has been no concrete study which presents the influence of phentermine on autonomic nervous system. Analysis of Heart rate variability is reliable, non-invasive and very useful for evaluating function of autonomic nervous system. We tried to elucidate the influence of phentermine on autonomic nervovs system by heart rate variability. MethodsAmong the 70 candidates who participated in the double-blind case control study whichwas designed in purpose of approving whether- Adipekⓓ is effective for treatment of obesity, 45persons were folled up. From April, 2005 to May 2005, HRV of the candidates who takes phentermine or placebo for 1month, was recorded using BFM-5000ⓓ(medi-core) for 5 minutes in resting state. HRV measures were assessed by time-domain and by frequency- domain analysis. Time domain parameters contain SDNN(Standard Deviation of NN intervals) and RMSSD(Root-Mean-Square of Successive Differences), etc and frequency domain Parameters contain Total Power(TP), Low frequency(LF'0.04-0.15Hz) power. High Frequency(HF:0.15-0.4Hz) power and LF/HF ratio etc. Results: Intakes of phentermine reduce HRV significant1y. SDNN & RMSSD, the main tine domain parameters of HRV, were decreased significantly(P=0.007. 0.016). PSI(Physical Stress Index of Pressure Index) was increase significantly(P=0.002)The main frequency domain parameters(TP, LF & VLF), also decreased significantly. (P=0.024,0.033, 0.015)Conclusion: The result showed that intakes of phentermine reduce heart rate variability and influence on most parameters of HRV. So phentermine not only accelerates sympathetic tone, but also inhibit the balance and function of autonomic nervous system.

• Journal of information and communication convergence engineering
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• 제8권2호
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• pp.201-204
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• 2010

In the mobile healthcare system, a very important vital sign in analyzing the status of user health is the HRV (heart rate variability). The used signals for measuring the HRV are electrocardiograph and PPG (photoplethysmograph). In extracting the HRV from the PPG signal, an important issue is that extract the exactly HRV from PPG signal distorted from the user's movements. This study suggested a design method of the Kalman filter to solve the problem, and evaluated the performances of a proposed method by PPG signals containing motion artifacts. In the results of experiments that compared with a variable step size adaptive filter proposed in recently, the proposed method showed better performance than an adaptive filter.

• 대한불안의학회지
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• 제3권1호
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• pp.26-31
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• 2007

Object : This study was designed to assess the change of heart rate variability (HRV) during stimulation test among the patients with major depressive disorder. Methods : 15 patients with major depressive disorder (MDD) and 15 normal controls were enrolled in this study. We sequentially measured HRV at baseline, during cognitive stimuli and emotional stimuli. Results : There are significant differences between the two groups in HRV index, TINN on baseline state and under cognitive stimulus. Conclusion : Stimulation protocol using HRV can be useful in estimating autonomic nervous function.

• 사상체질의학회지
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• 제19권3호
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• pp.176-187
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• 2007

1. Objectives The purpose of this research is to find out the Sasang Constitutional difference in Heart Rate Variability. 2. Methods We enrolled 8498 workers who tested for Heart Rate Variability(HRV) from September 1, 2005 to November 28, 2005 except works whose body constitusions were undetermined according to QSCCII. 3. Results & Conclusions The result of HRV of autonomic activity and stress resistance were arranged in the order of Soeumin, Soyangin and Taeumin. On the other hand Stress Index and Fatigue Index were arranged in the order of Taeumin, Soyangin and Soeumin. But autonomic balance was no significance relationship between Sasang Constitutions. This research has shown that there is a statistical significance between the HRV and Sasang Constitutions. The findings indicated that HRV could be useful mean to make a diagnosis of Sasang Constitution or apprehended Constitutional differences.

• 한방안이비인후피부과학회지
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• 제22권1호
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• pp.133-140
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• 2009

Objective : To evaluate autonomic nerve balance and sympathetic nerve activity in patients with inner ear dysfunction as examined by heart rate variability(HRV) Research Methods and Procedures : One hundred and twenty three patients(between 15 to 59 years old) who visited Dept. of Oriental medical Opthalmology & Otolaryngology, Kyunghee university and had an examination of HRV test, were selected as subjects of our study. We checked items of HRV test(such as SDNN, RMSSD, LF, HF, TP, norm-LF, norm-HF, LF/HF ratio), and analyzed time and frequency domain differences between three groups classified as tinnitus, hearing loss and vertigo. And we compared HRV items(such as SDNN,RMSSD, TP and LF/HF ratio) with standard levels. Results and Conclusion : Our results showed no significant differences between three groups in HRV items except for mean heart rate. Patients with inner ear dysfunction showed significant lower TP than 2000$(ms^{2})$(p <0.001) and significant higher LF/HF ratio than 1.5(p=0.003). So we suggest that patients with inner ear dysfunctions such as tinnitus, vertigo and hearing loss, have sympathetic hypertonus and inactivity of autonomic nerve regulation.

• 전기학회논문지
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• 제58권5호
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• pp.1050-1056
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• 2009

Heart Rate Variability(HRV) is a parameter that represents monitoring variability of time intervals between R-peak in electrocardiography. HRV serves to various applications, such as indices of autonomic functions, prediction of cardiac sudden death, assessment of stress and emotional, etc. However, as measuring R-peak in ECG needs at least 3-electrodes, and it is inconvenient for end users. In this paper, we suggested the modified laplacian electrodes for measuring HRV at one-point, which are producted by MEMS fabrication and have the two circular electrodes on the pad. For optimal position and direction, we performed an experiment that compared with pearson correlation coefficient and the amplitude of signals, between standard lead II and proposed electrodes. We analyzed the HRV parameters, such as standard deviation of the NN interval(SDNN), high frequency(HF), low frequency(LF), LF/HF ratio. The result showed that the average correlation coefficient and amplitude are 0.967 and 0.685 mVpp at the position 2. The coeffiecient correlation between the standard HRV and proposed electrode-HRV is 0.999

• 정신신체의학
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• 제21권1호
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• pp.55-61
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• 2013

연구목적 알츠하이머병(Alzheimer's disease, 이하 AD)과 경도 인지 장애(Mild cognitive impairment, 이하 MCI)는 자율신경계를 포함한 여러 신경 기능에 영향을 미친다. 신경정신과적 장애와 심박 변이도(Heart rate variability, 이하 HRV)간의 연관성은 많이 연구되어 왔지만, AD에서 심혈관계 자율신경 기능에 관한 연구는 시행된 바가 적고, 연구 결과도 일관되지 않는다. 이에 본 연구는 HRV의 분석을 통하여 AD, MCI 그리고 정상 대조군에서 자율 신경계의 활성도 차이를 평가하고자 하였다. 방 법 5분 동안 RR 간격의 시간, 주파수 영역 변이도가 26명의 정상 대조군, 22명의 MCI군, 34명의 AD군에서 각각 평가되었다. 그룹 간 차이를 평가하기 위해 일원배치 분산분석(Analysis of variance, ANOVA)이 사용되었으며, MMSE-KC와 HRV 요소 간의 상관관계는 피어슨 상관계수(Pearson's correlation coefficient)로 평가되었다. 결 과 HRV의 시간, 주파수 영역 분석에서 그룹간의 의미 있는 차이는 관찰되지 않았다. 인지 기능 장애 정도와 HRV 간의 상관 관계도 유의하지 않은 것으로 나타났다. 결 론 정상 대조군과 비교하였을 때 MCI, AD군의 HRV 요소는 통계적으로 유의한 차이가 없는 것으로 나타났다. MCI와 AD의 비침습적인 검사 도구로써 HRV가 사용되기 위해서는 후속적인 연구가 필요할 것으로 생각된다.