• 한국어병학회지
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• 제13권1호
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• pp.21-29
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• 2000

1997년 9월 전북 부안군 소재의 동자개(Pseudobagrus fulvidraco) 양어장에서 작은 소리에도 과도하게 놀라고, 새변의 유착과 곤봉화를 특징으로 하는 질병이 발생하여 대량폐사를 초래한 pantothenic acid 결핍에 의한 사료성 아가미병의 병리상과 사망률을 줄이기 위한 방책을 수립하였다. 질병이 발생한 양어장의 수질은 다른 양어장의 수치와 비슷하였고, 병어에서 세균이 분리되지 않았다. 병어는 적혈구 수, Hb, Ht 및 간중량지수의 감소, 적혈구의 소형화와 간의 위축을 나타내는 전형적인 pantothenic acid 결핍에 의한 사료성 아가미병으로 판명되었다. 새변의 상피세포의 증생과 유착을 완화시키기 위해 0.5%와 0.6% 식염을 첨가하여 10일간 사육한 결과 0.5%와 대조구(식염 무첨가구)는 100% 사망하였으나, 0.6% 식염 첨구가구는 75%의 생존율을 나타냄과 동시에 새변 상피세포의 증생과 유착이 감소하였다. Pantothenic acid 10 mg/kg 사료를 25일간 급이하며 5, 10, 15, 25일 간격으로 채취하여 질병의 호전상태를 혈액학적, 병리조직학적으로 검사한 결과 pantothenic acid 첨가사료 급이 25일 후 적혈구 수, Hb, Ht, 간중량지수와 아가미 조직도 정상의 상태로 회복되었다. 병리조직학적 검사에서는 15일부터 상피세포의 증생이 줄어들어 호흡면적이 현저하게 증가하였고 급이 25일 후에는 거의 정상상태로 회복되었다. 본 연구의 결과 동자개의 pantothenic acid 결핍에 의한 사료성 아가미병의 경우 식염 0.6%에서 사육하는것과 pantothenic acid 10 mg/kg 사료 첨가하여 최소한 25일간 사육하는 것이 효과적인 것으로 나타났다.

• 한국치위생학회지
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• 제8권4호
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• pp.205-217
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• 2008

The purpose of this study was to provide information on the development of an oral-health promotion program geared toward office workers. The subjects in this study were 240 employees at the headquarters of S construction company. After a survey was conducted in July and August 2008, the answer sheets from 208 respondents were gathered, and 191 answer sheets were analyzed except 17 unanalyzable ones. The findings of the study were as follows: 1. In regard to subjective oral health status, the largest number of the participants that accounted for 37.2% found their mouth to be neither healthy nor unhealthy. The greatest number of them that represented 58.1% had never visited a dentist's office to receive preventive treatment. 2. Regarding relationship between toothbrushing education experience and toothbrushing frequency, the most common toothbrushing frequency was three times a day( 46.5%) among the company employees who had ever received that education. In the event of the office workers without that experience, the most prevalent frequency was three times(63.6%). The toothbrushing frequency was statistically significantly different according to the toothbrushing education experience(p<0.05). As to the relationship of toothbrushing education experience to tooth- brushing method, the largest number(48.2%) of those who had ever received that education brushed their upper and lower teeth along with the gums by rotating the toothbrush downward from the top and upward from the bottom respectively. In the event of the office workers without that experience, 49.4 percent brushed their teeth and gums by rotating the toothbrush up and down. Thus, whether they had ever received education about toothbrushing made a statistically significant difference to their toothbrushing method(p<0.05). 3. As a result of evaluating their oral health belief by utilizing a five-point scale, they got a mean of 2.95. In each area of oral health belief, they got the best marks in benefit(3.66), salience(3.42), barrier(2.84), susceptility(2.58) and seriousness(2.23). Given the above-mentioned finding of the study, two sorts of oral health beliefs, which are benefit and salience, should be stressed in the development of oral health education programs that cater to company employees. And sustained research efforts should be channeled into finding out the relationship between oral health and actual oral health care.

• 치위생과학회지
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• 제18권2호
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• pp.105-112
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• 2018

The purpose of this study was to focus on the number of brushing strokes among the performance factors and identify if the 10 times stroke of the rolling method is rational. Moreover, we evaluated the changes in oral health knowledge, perception, and behavior after our rolling method instruction. The 10-stroke method of toothbrushing has been regarded as an effective method of removal of dental plaque, although there is little evidence to support this claim. We allocated 40 healthy subjects to two intervention groups. During five visits, we measured a score for dental plaque removal and instructed the subjects on a toothbrushing technique with 5 or 10 strokes per section. At the initial and final visits, subjects completed a questionnaire on one designed specifically for this study about oral health knowledge, perceptions, and behaviors. Repeated measures analysis of variance was used to compare the dental plaque removal score between the groups, and the changes in scores within each group over time. We also compared changes in mean scores in oral health knowledge, perceptions and behaviors before and after toothbrushing instruction. We found that the score for dental plaque removal increased with each additional toothbrushing instruction in both groups (p<0.001). However, we found no differences in the dental plaque removal scores between the 5-stroke and 10-stroke groups (p=0.399). The levels of oral health knowledge, perceptions and behaviors increased after the toothbrushing instructions in both groups. Our findings suggest that there is no advantage in emphasizing the 10-stroke method of toothbrushing in an oral health education program.

• 동아시아식생활학회지
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• 제15권5
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• pp.516-523
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• 2005

This study was performed to investigate dietary behaviors and consumption of health food in cancer patients. The subjects were 163 cancer patients recruited from the general hospital in Seoul, Korea. The data were obtained by the structured self administered questionnaire. The mean age of subjects was 51 years. Most of subjects didn't eat the visual fat of meat and chicken skin. The mealtime of the subjects was generally regular and most of subjects had breakfast. The subjects of this survey liked to eat foods with sweet taste but disliked to eat hot, salty and sour taste ones. The preference for fish, marine products and vegetables was high but that for instant foods and frying foods was very low. Most of subjects consumed the foods that is generally known as anticancer foods such as vegetables and fruits. On the other hand, most of subjects didn't intake butter, margarine, and frying foods that is known as risk factors of cancer. The majority of subjects$(84.7\%)$ consumed the health food The main reasons for taking health foods by subjects were to cure disease$(58.0\%)$, to prevent disease$(45.3\%)$, to supply nutrients$(39.3\%)$, to maintain the mental state$(12.7\%)$ and to recover fatigue$(10.7\%)$. Majority of subjects$(66.0\%)$ spent money more than 200,000 won/month to buy health foods. The purchasing channels of health foods by subjects were recommendation by family or friend$(64.0\%)$, by physician/pharmacist$(18.0\%)$ and by nutritionist or dietician(6.0), and advertisement through TV or radio$(12.0\%)$. The types of taking health foods of the subjects were vegetable extracted food$(60.0\%)$, mushrooms$(51.3\%)$, Lactobacillus food$(25.3\%)$, enzyme food$(22.6\%)$ calcium containing food$(20.0\%)$ and so on. The results of the current study show that although many cancer patients already practice healthy dietary behaviors, there is a substantial proportion who do not and most of cancer patients consume health foods.' Further intervention is needed to explore the effect of health foods in cancer patients

• 경영과정보연구
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• 제34권3호
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• pp.125-140
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• 2015

본 연구에서는 현행 4부의 코스닥소속부제의 실효성을 검증하기 위해 현 제도에 따라 우량기업부로 구분된 기업집단을 대상으로 우량기업부 진입 전 후 기간의 이익조정 추세를 검토하였다. 구체적으로 2011년 현 소속부제의 시행에 따라 우량기업부에 진입한 111개 기업을 대상으로 우량기업부 진입 당해 연도와 진입 이전 이후 2개년을 포함한 총 5개 년도의 재량적 발생액과 실물이익조정치의 변화추이를 살펴보았다. 주요한 분석결과를 요약하면 다음과 같다. 먼저, 우량기업부에 소속된 기업만을 대상으로 우량기업부 편입 전 후 기간의 이익조정 추세를 검증한 결과 우량기업부 진입 직전 기간에 모든 이익조정 대용변수가 양(+)방향으로 크게 증가하며 그러한 이익조정치의 평균값이 통계적으로 유의하게 영(0)과 차이가 나는 것으로 나타났다. 또한, 우량기업부 진입 직전기간의 증가적 이익조정 현상이 이익조정에 영향을 미칠 수 있는 다양한 변인들을 통제한 다변량 분석체계에서도 다시금 입증되고 있음을 확인하였다. 이는 현행 소속부제의 평가시스템이 기업의 재무적 관점에 다소 편중되어 있어 내적가치가 부실한 기업이 우량기업부 진입을 통해 다양한 혜택을 누리고자 소속부 평가에 기초가 되는 우량기업부 진입 직전의 보고이익을 발생액 및 실물활동을 통해 광범위하게 증가시키는 경향이 있음을 보여준다. 이와 같은 본 연구의 결과는 증권시장에 대한 감독기관과 규제기관이 현행 소속부제의 공과 실을 면밀히 파악하여 부실기업과 우량기업을 보다 효과적으로 판별할 수 있는 제도적 장치의 마련을 강구하는 등 코스닥시장의 건전성 회복과 활성화를 위해 소속부제의 효익이 충분히 발휘될 수 있도록 운용의 묘를 살릴 필요가 있다는 정책적 시사점을 제공한다.

• 한국식품영양학회지
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• 제29권2호
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• pp.267-274
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• 2016

Increasing sugar intake of population has become a nutritional issue in Korea. Sweet taste perception may be related to behaviors such as eating sweet food including high sugars and total sugar intake. This study aimed to evaluate objective and subjective sweet taste perception and the association among objective sweet taste perception, dietary behaviors related to eating sweet snack food including high sugar, and total sugar intake from the snacks. Participants were 261 healthy female college students (mean age: $21.0{\pm}1.6years$), who were divided into three subgroups based on oral sweet taste evaluation using a sweet taste assessment tool provided by Ministry of Food and Drug Safety: sweet-seeker group (n=139), medium sweet-seeker group (n=54), and unsweet-seeker group (n=68). There was no significant difference in weight and body mass index (BMI) among the three groups; however, the sweet-seeker group had significantly higher sweet taste preference than that of the other groups. Though more people in the sweet-seeker group thought they tended to eat sweet foods than the medium sweet-seeker and unsweet-seeker groups, over half of the sweet-seekers did not think they tended to eat sweet foods. The sweet-seeker group was more likely to eat sweet snacks such as breads, chocolate products, sugar-sweetened milk, and so on than the unsweet-seeker group. Total sugar intake from the selected sweet snacks was 44.4 g for the sweet-seeker group, 34.4 g for the medium sweet-seeker group, and 28.0 g for the unsweet-seeker group with a significant difference. These results indicated the absence of relationship between objective sweet taste perception and the obesity index; however, significant associations were detected among objective sweet taste perception, eating sweet snacks and total sugar intake from the snacks. We also found high disagreement between objective and subjective sweet taste perception of the subjects. The present study provided the novel insight that measuring objective sweet taste perception may be useful for assessing the risk of high sugar consumption and undesirable dietary behaviors.

• 인간행동과 음악연구
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• 제12권2호
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• pp.1-18
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• 2015

본 연구의 목적은 뇌성마비 성인과 일반 성인에게 각각 동일한 발화과제(일반, 리듬, 선율 발화)를 제공한 뒤 집단(일반 및 뇌성마비 성인)과 발화과제에 따라 어떠한 음성 특성이 나타나는지 알아보는 것이다. 연구대상은 뇌성마비 성인 20명과 일반 성인 20명이며 프라트(Praat) 프로그램을 사용하여 발화과제에 따른 기본주파수, 음성강도, 주파수 변동률, 진폭 변동률수치를 구하였다. 각 집단의 발화 과제에 따른 음성 특성 분석 결과, 기본주파수와 음성강도의 경우 두 집단 모두 유의한 차이는 없었으나 주파수 변동률 및 진폭 변동률의 경우 일반성인집단과 뇌성마비성인집단 모두 선율 발화 시 유의하게 가장 낮은 수치를 보였다. 집단에 따른 차이를 분석한 결과, 뇌성마비성인집단의 주파수 변동률 및 진폭 변동률이 일반성인집단에 비해 유의하게 높은 수치를 보였다. 또한 일반성인집단과는 달리 뇌성마비성인집단의 경우 리듬 발화 시 주파수 변동률 및 진폭 변동률 수치가 가장 높게 나타났으며 주파수변동률의 경우 집단과 발화과제 종류에 따른 상호작용 효과가 유의해 두 집단 사이에 상이한 양상이 발견되었다. 본 연구는 발화 시 적용된 음악요소에 따라 나타나는 즉각적 음성 특성에 대한 정보를 제공해주는 기초자료로 사용될 수 있다.

• 융합정보논문지
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• 제10권7호
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• pp.58-66
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• 2020

본 연구의 목적은 고혈압환자의 생애주기별 건강행태와 삶의 질과의 관계를 파악하는 것이다. 본 연구는 2017년 지역사회건강조사의 자료를 가지고 2차 자료를 분석하여 실시하였다. 연구대상은 고혈압을 진단받은 총 62,056명을 대상으로 삼았다. 자료분석은 SPSS WIN 20.0을 이용하여 분석하였다. 연구결과 첫째, 고혈압치료 및 약물순응도는 성인기에서 중장년기, 노년기보다 훨씬 낮게 나타났다. 둘째, 생애주기별 삶의 질 점수는 성인기가 가장 높았고 연령이 증가할수록 낮아지는 것으로 확인되었다. 셋째, 건강행태에 따른 삶의 질은 생애주기 전반에서 음주, 운동, 저염식이에 따라 차이를 보였다. 본 연구에서 제시된 결과를 고려하여 고혈압환자의 평생 건강관리를 위한 생애주기별 보건교육이 필수적임을 시사하며, 특히 성인기의 고혈압환자의 약물순응도를 높일 수 있는 방안을 개발하고, 삶의 질을 향상을 위한 건전한 건강행태를 가질 수 있도록 교육 및 의학적 접근 등 융복합적 접근이 필요할 것으로 판단된다.

• 폴리머
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• 제38권3호
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• pp.364-370
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• 2014

망막색소상피(RPE)는 건강한 망막을 유지하는데 중요한 역할을 하고 RPE의 퇴화는 많은 망막질병을 유발한다. RPE 이식은 최근 망막 퇴화에 대한 가능성 있는 치료법으로 제시되고 있다. RPE 세포를 안전하게 이식하기 위해서는 지지체가 필요하므로 독특한 기계적 성질과 생체적합성을 갖는 실크를 사용하여 필름을 제조하였다. 실크필름의 FTIR, 접촉각 및 생분해성을 측정한 후, RPE 세포를 실크필름에 파종하여 그 영향을 확인하였다. MTT 분석, SEM, 면역형광염색, RT-PCR을 통해 세포의 부착, 생존도, 형태유지, 특이적 mRNA의 발현을 분석하였다. 본 연구에서는, 실크필름에 배양한 RPE 세포의 부착, 증식 및 표현형 유지가 뛰어남을 확인함으로써 실크필름의 망막 재생을 위한 조직 공학적 지지체로의 응용 가능성을 제시했다.

• Child Health Nursing Research
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• 제7권1호
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• pp.35-50
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• 2001

The ability of neonates to perceive and react to pain, has been acknowledged recently. Recent researches have been shown that even short term pain can have lasting negative effects. We know that most of the anatomical pathway and neurotrans-mitter function necessary for pain perception are fully or nearly fully developed in the neonatal period. Many people are still reluctant to believe that pain felt by neonates may be as severe as that felt by older children or adults yet. The objective of the study is to assess and compare the analgesic effects of orally administered sucrose and pacifiers. And to determine the synergistic analgesic effects of sucrose and pacifiers. The tools for this study is Lawrence's NIPS (neonatal infant pain scale) with behavioural pain responses and index for pain physiological reponses as heart rate, respiratory rate and degree of SaO₂. The participants are 96 healthy infants of neonatal age 1-7days and randomised to receive heel prick before 2minutes to blood sampling and physiological test in Nursery of K Medical University Hospital on May-July, 2000. The experimental group assigned to one of three treatment groups : no treatment; a pacifier; placebo(2ml 25％ sucrose). Collected data were analyzed with the SAS program using X²-test, ANOVA and Duncan's multiple range test as post hoc. The results were as follows. 1) Pain behaviour responses: The pain score of placebo group(2ml 25％ sucrose) is lower than no treatment group and pacifier group significantly(P=.000). Placebo group is different from no treatment and pacifier group with Duncan's multiple range test. 2) Pain physiologic responses (1) heart rate: The heart rate of placebo group(2ml 25％ sucrose) is different from that of no treatment group and pacifier group significantly(P=.000). The heart rate change of placebo group is less than the other groups. (2) respiratory rate: The respiratory rate of placebo group(2ml 25％ sucrose) is different from that of no treatment group and pacifier group insignificantly (P=.2340). But, the respiratory rate of placebo group is lower than the other groups. (3) SaO₂: The SaO₂ score of placebo group(2ml 25％ sucrose) is different from that of no treatment group and pacifier group insignificantly (P=.3265). But, the change of SaO₂ score of placebo group is less than the other groups. In conclusion, the sucrose placebo showed pain relief effect in behavior responses and less physiological responses. Accordingly, the sucrose placebo should be applied nursing intervention for simple pain management as heel prick.