• Title/Summary/Keyword: healthcare research

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A study on the patterns of expression of the DAZ and HSP genes in the testicular tissue of men with azoospermia

  • Lee, Ho-Joon;Lee, Hyoung-Song;Song, Gyun-Jee;Byun, Hye-Kyung;Cho, Youl-Hee;Kim, Jong-Hyun;Seo, Ju-Tae;Lee, Yoo-Sik
    • Journal of Genetic Medicine
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    • v.1 no.1
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    • pp.51-56
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    • 1997
  • Spermatogenesis is known to be regulated by a number of genes and several factors such as hormones, growth factors, cytokines and others. This study was done to evaluate the relationship between HSPs and DAZ genes in human spermatogenesis; we observed the expression pattern of HSP gene in azoospermia men with DAZ gene that regulated the gene expression related with human spermatogenesis. RT-PCR method was used to detect DAZ, HSP70A, and HSP70B transcripts in all RNA samples. Total RNA was extracted from 21 testis tissues using TRIZOL reagent. cDNAs were synthesized with reverse transcriptase, AMV. All PCR reaction were performed on a PCR themocycler with DAZ, HSP70A, and HSP70B-specific primers. Semen analysis, karyotyping and testis histology were performed. DAZ gene, known as a candidate gene of azoospermia factor(AZF), was deleted in 2 of 21 patients. To evaluate the only effects of HSPs in this patients, 2 DAZ deleted cases were removed. We observed the mRNA of HSP70B in 5 whereas none could be seen with regard to HSP70A. Furthermore, the sperm of these 5 men were discovered to be immature. In conclusion, HSP70B as well ad DAZ gene seem to be involved causing spermatogenic failure. We suggest that HSP70B plays an important role in spermatogenesis and it is one of factors induced sperm maturation in human.

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Unmet Healthcare Needs Status and Trend of Korea in 2018 (2018 미충족의료율과 추이)

  • Joo, Jae Hong;Kim, Hwi Jun;Jang, Jieun;Park, Eun-Cheol;Jang, Sung-In
    • Health Policy and Management
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    • v.30 no.1
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    • pp.120-125
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    • 2020
  • Unmet healthcare needs lead to increased disease severity, increased likelihood of complications, and worse disease prognosis. To examine the latest status of unmet healthcare needs in South Korea, the four different data configured with nationally representative sample of South Korean population were used: the Korea Health and Nutrition Examination Survey (KNAHANES, 2007-2018), the Community Health Survey (CHS, 2008-2018), the Korea Health Panel Survey (KHP, 2011-2016), and the Korean Welfare Panel Study (KOWEPS, 2006-2018). The proportion of individuals reporting unmet healthcare needs were 7.8% (KNHANES, 2018), 8.8% (CHS), and 10.8% (KHP, 2016). Annual percentage change which characterizes trend for the follow-up period was -9.1%, -3.2%, and -6.8%, respectively. The proportion of individuals reporting unmet healthcare needs due to cost were 1.2% (KNAHANES, 2018), 1.2% (CHS, 2018), 2.5% (KHP, 2016), and 0.5% (KOWEPS, 2018). Annual percentage change which characterizes trend for the follow-up period was -10.3%, -12.0%, -11.3%, and -18.8, respectively. The low-income population and the elderly population were vulnerable groups reporting the highest rate of unmet health care needs. The rate of unmet healthcare needs has been declining since the past decade, still, the disparity between different income groups and age groups suggests that there are many challenges to address.

Healing Function Evaluation of Color Samples from the Healthcare Environmental Color Index - A Cross-cultural Comparison Study on Korean and Romanian users

  • Ardelean, Ioana;Oh, Jiyoung;Park, Heykyung
    • International Journal of Advanced Culture Technology
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    • v.9 no.3
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    • pp.131-141
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    • 2021
  • The present study is following a series of research investigations on design resources coming from collected data referring to users' awareness and preferences. The aim of this research is to test the Healthcare Environmental Color Index as a basis for practitioners in the field of healthcare design. An array of color samples selected from previous research, have been presented to the respondents via an online survey, in order to identify the preferences of the two groups on the relation between environmental color and health. As a result of the first experiment and through the comparison of processed data, the maximum percentage of respondents from each group is validating the relation between environmental color and health. For the second experiment we intend to highlight the patterns of color preferences for each group, and thus to test the color samples healing function. The compared data also showed a higher awareness of Koreans than Romanians on the potential of color applied to healing environment. Last but not least in the third experiment we show the top five color samples preferred by each group. It is significant that the comparison of the results validated once more some of our previous findings related to the healthcare environment, such as: the general preference for the green hue (associated to fatigue relax according to color psychology) and the blue hue (sedation release effect) but also the yellow hue - associated to bright energy. Three out of the top five preferred color samples have been identical to both groups while the other two samples have shown characteristic variations. These results show that similarities are strong and can be used in a glocal design strategy as an accessible tool for any practitioner. Based on the Healthcare Environmental Color Index and users' preferences analysis, a new design culture for healthcare can be established and developed.

Improvement of ECG Measurement for the Elderly's U-healthcare Clothing Using 3D Tight-fit Pattern (3D패턴을 이용한 노인용 u-헬스케어 의복의 심전도 측정 연구)

  • Park, Hye-Jun;Shin, Seung-Chul;Shon, Boo-Hyun;Hong, Kyung-Hi
    • Fashion & Textile Research Journal
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    • v.10 no.5
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    • pp.676-682
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    • 2008
  • In this study a guideline of the 3D-fit pattern for the ECG(electrocardiogram) measurement of elderly's u-healthcare clothes was proposed. In the screening test of the ECG measurement band, ECG peak band was observable at the band pressure of 0.20 kPa. By employing a 3D body image, tight-fit 3D patterns were made at two different reduction rates of 21%(pattern 1) and 33%(pattern 2), and corresponding pressure of both of the clothes were 0.25 kPa and 0.54 kPa, respectively. Typical waves of ECG were found in both stationary and moving position. In terms of the subjective evaluation of the u-healthcare clothes when worn, it was confirmed that reduction pattern 1(0.25 kPa) conveyed comfortable clothing pressure and pleasantness, which is very close to the result of screening test of ECG band experiment. As results, it is recommended that reduction rate should be adjusted, so that clothing pressure is about 0.2 kPa for the elderly's comfortable and efficient u-healthcare clothes.

Impact of Healthcare Accreditation Using a Systematic Review: Balanced Score Card Perspective (의료기관인증의 효과에 대한 체계적 문헌고찰: Balanced Score Card 관점으로)

  • Park, Il-Tae;Jung, Yoen-Yi;Park, Seong-Hi;Hwang, Jeong-Hae;Suk, Seung-Han
    • Quality Improvement in Health Care
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    • v.23 no.1
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    • pp.69-90
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    • 2017
  • Purpose: The purpose of this study was to analyze the impact of healthcare accreditation and to provide empirical evidence to validate positive effectiveness. Methods:Six electronic databases (KERIS, KoreaMed, NDSL, Ovid-medline, Embase, Cochrane library) were accessed in May 2016. Keywords used were 'accreditation' and 'Joint Commission on Accreditation of Healthcare Organization (JCAHO)'. Of the initially identified 3,008 articles, 60 studies on healthcare accreditation were selected based on inclusion criteria that are hospital accreditation, accreditation by disease and clinical center accreditation. These were retrieved and analyzed. Result: The 60 study results were on the impact of healthcare accreditation. Results were classified into four perspectives of Balanced Score Card (Financial, Customer, Internal Process, Learning & Growth). In internal process perspective, results revealed that healthcare accreditation has made a positive impact on "care process and procedure". In learning & growth perspective, healthcare accreditation has made a positive influence on "leadership", "organizational cultures" and "change mechanisms". However, it revealed that healthcare accreditation does not directly affect financial performance. It is also difficult to reach a definitive conclusion that healthcare accreditation programs affect patient satisfaction of customer and clinical outcome of the internal process. Conclusion: Healthcare accreditation programs provide positive impact on change of care process and building communication-oriented hospital culture. However, more rigorous and diverse research is needed on financial effects and clinical outcomes of healthcare accreditation.

Personalized Healthcare System for Chronic Disease Care in Cloud Environment

  • Jeong, Sangjin;Kim, Yong-Woon;Youn, Chan-Hyun
    • ETRI Journal
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    • v.36 no.5
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    • pp.730-740
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    • 2014
  • The rapid increase in the number of patients with chronic diseases is an important public healthcare issue in many countries, which accelerates many studies on a healthcare system that can, whenever and wherever, extract and process patient data. A patient with a chronic disease conducts self-management in an out-of-hospital environment, particularly in an at-home environment, so it is important to provide integrated and personalized healthcare services for effective care. To help provide effective care for chronic disease patients, we propose a service flow and a new cloud-based personalized healthcare system architecture supporting both at-home and at-hospital environments. The system considers the different characteristics of at-hospital and at-home environments, and it provides various chronic disease care services. A prototype implementation and a predicted cost model are provided to show the effectiveness of the system. The proposed personalized healthcare system can support cost-effective disease care in an at-hospital environment and personalized self-management of chronic disease in an at-home environment.

A multi-item measurement scale of healthcare service quality: an evaluation indicators of healthcare certification (의료서비스 품질 측정 요인: 의료서비스 인증 평가지표를 중심으로)

  • Choe, Byung-Don;Lee, Don-Hee;Yoon, Sung-Dae
    • Journal of Korean Society for Quality Management
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    • v.40 no.3
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    • pp.381-393
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    • 2012
  • Purpose: Considering various measurements for healthcare service quality, the purpose of this study is to examine measurement items for healthcare service quality (HCSQ) based on previous study and service quality evaluation institutions in the international community. Methods: The proposed research model was tested using measurement analysis, based on data collected from 387 respondents in the selected hospital with more than 500 beds in South Korea. Results: The results of the study shed insights about the relative importance of quality items as degree of improvements of care services tangible, safety, efficiency, and empathy. Also, the study provides new measurement model for healthcare service quality. Conclusion: Healthcare organization thrives to find the key factors for improving quality of care and service that meet customers' needs and expectations.

Physiological Effects of the Cosmetic Product Containing of Saccharomyces Fermented Modified Kyungohkgo Extract on Human Skin (경옥고(瓊玉膏) 가미방(加味方) 효모(酵母) 발효물(醱酵物)함유 한방화장품(韓方化粧品)이 인체(人體) 피부(皮膚) 생리(生理)에 미치는 영향(影響))

  • Choi, Jae-Hwan;Kim, Hyoung-Man;Song, Young-Sook;Park, Sun-Gyoo;Kim, Jin-Jun;Lee, Cheon-Koo
    • The Korea Journal of Herbology
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    • v.22 no.4
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    • pp.227-232
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    • 2007
  • Objectives : We investigated the physiological effects of the cosmetic products with Saccharomyces fermented modified Kyungohkgo extract (SFKE) for 6 weeks on human skin by using non-invasive instruments. Methods : We measured physiological effects such as a skin moisturizing effect, an elasticity and an evenness on the skin of older than 40 years volunteers(female, n=25) who were applied with the cosmetic products containing SFKE for 6 weeks. Results : We observed the physiological effect after using the cosmetic products for 6 weeks. After using the cosmetic product, the skin moisture contents were increased in human skin. The skin elasticity were not only increased in face skin through using the product, but also evenness of skin were improved. Conclusions : We concluded that the cosmetic products containing the SFKE had and physiological effects on the human face skin.

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An Analysis of Health Promotion Programs Utilizing Forests based on Korea's Regional Healthcare Program Plans (지역보건의료계획에 근거한 보건소 숲 건강증진 프로그램 현황)

  • Lee, Insook;Kim, Sungjae;Bang, Kyung-Sook;Choi, Heeseung;Ko, Chinkang;Kim, Jieun;Kim, Sunyoung
    • Perspectives in Nursing Science
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    • v.11 no.1
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    • pp.10-17
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    • 2014
  • Purpose: The aim of this study was to analyze health promotion programs utilizing forests by reviewing regional healthcare program plans in Korea. Methods: We analyzed 227 regional healthcare program plans from 2011 to 2014; seven health promotion programs of the 16 major healthcare programs were prescribed by public health law. Results: Our analysis revealed that only 35 health promotion programs from 29 sites were utilizing forests. Furthermore, of 21 known categories of health promotion programs, only nine incorporated the use of forests. Atopy-asthma healthcare programs were the most common forest health promotion programs, which also included specialized disease management programs (e.g., for atopy prevention and healing, patients with metabolic syndrome or cancer) and specialized mental health management programs (e.g., for addiction or dementia prevention). Others included programs on the development of forest roads or industrial development using forest products. Conclusion: Health programs using forests in Korea are still very limited and primarily comprise atopy-asthma prevention/management, health behavioral change, and mental health programs. This study provided useful information for developing health policies and forest health promotion programs further in Korea.

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