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Effects of Egg White Consumption on Immune Modulation in a Mouse Model of Trimellitic Anhydride-induced Allergy

  • Kim, Ji-Hyuk;Song, Hyuk;Kim, Hyoun Wook;Lee, Won-Young
    • Food Science of Animal Resources
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    • v.35 no.3
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    • pp.398-405
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    • 2015
  • Egg allergy has been shown to be the most common food allergy in children with atopic dermatitis. Allergic reactions to proteins derived from egg white (EW) are more common than those derived from egg yolk. Ovomucoid, ovalbumin, ovotransferrin, and lysozyme have been identified as major allergens in EW. This study was conducted to evaluate the effect of EW on immune modulation in an induced allergy mouse model. A total of 50 five-week-old BALB/c male mice were treated with trimellitic anhydride (TMA) for three weeks to induce allergy-like symptoms. The TMA-treated mice were rested for one week and then divided into five groups and fed 0, 10, 50, and 100 mg/d EW for four weeks. All EW consumption groups showed no significant increase or decrease in the populations of white blood cells; however, a significant increase in B-lymphocyte activity was observed in the fourth week. Furthermore, EW consumption did not influence serum immunoglobulin G and immunoglobulin E levels. Taken together, these data demonstrate that the consumption of EW by TMA-treated mice did not increase allergic parameters such as serum IgE level, but enhanced the lymphocyte activities against pathogens. Therefore, this study suggests that the consumption of EW promotes Th2 immune modulation, and EW could be an excellent candidate for maintaining health.

Airway Obstruction and Respiratory Distress Owing to Sedation by use of Chloral Hydrate & Ketamine Before Extraction of the Mesiodens in Patient with Bronchial Asthma & Tonsillar Hyperplasia -A Case Report- (기관지 천식과 편도 증식증 환자에서 상악 정중부 과잉치 발치 전 포크랄과 케타민 투여 진정요법 시 발생된 기도폐쇄와 호흡장애 -증례 보고-)

  • Choi, Young-Su;Kang, Sang-Hoon;Kim, Moon-Key;Lee, Chun-Ui;Yoo, Jae-Ha
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.10 no.1
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    • pp.34-44
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    • 2010
  • The causes for airway obstruction include foreign body aspiration, congenital structural abnormalities of the airway, infection, etc. And the potential causes of acute respiratory distress contain many situations, like hyperventilation, vasodepressor syncope, asthma, etc. A major factor that leads to the exacerbation of respiratory disorders is undue stress, either physiologic or psychologic. Psychologic stress in dentistry is the primary factor in the exacerbation of preexisting medical problems. Adequate pretreatment medical and dental evaluation of the prospective patient can often prevent respiratory problems from developing. The dentist can modify patient management to minimize the risk of exacerbating these conditions. When dental anxiety is a major factor, the use of psychosedative procedures and other stress-reduction techniques should also be considered. This is the report of a children case of airway obstruction and respiratory distress owing to sedation complication by use of Chloral hydrate and Ketamine before extraction of the mesiodens in a patient with bronchial asthma and tonsillar hyperplasia. After these situations, the patient was consulted & referred to the department of Pediatrics and Otorhinolaryngology.

A Study on Exercise Performance and Its Relating Factors in Middle-aged Women (중년여성의 운동수행실태와 운동수행에 영향을 미치는 요인)

  • Oh, Sung-Jae;Kim, Jeung-Im;Chae, Young-Ran
    • Women's Health Nursing
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    • v.16 no.4
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    • pp.348-359
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    • 2010
  • Purpose: This study was done to identify practical exercise performance and to define the factors related to exercise performance in middle-aged women. Methods: The researchers collected data from 206 middle-aged women, ages 40 to 59. The measurements used were a scale for degree of exercise performance, and self-efficacy scale, affect, perceived barriers and benefits related exercise, body-shape perception, and the youngest child's education stage. The data were analyzed with SPSS/WIN 17.0 and SAS program using t-test, ANOVA, and stepwise multiple regression. Results: Exercise performance showed significant differences according to body-shape perception (F=5.45, p<.01), the youngest child's education stage (F=4.44, p<.05). Exercise performance had a significant strong positive relation with self-efficacy (r=.616), a moderate relation with self-rated health (r=.428) and with affect related exercise (r=.519), a mild relation with perceived benefits (r=.339) and with social support (r=.239), and a negative mild relation with perceived barriers (r=-.330) with 99% significance. Self-efficacy, affect, perceived barriers, and the youngest child's education stage explained 46.4% of a variance in exercise performance in middle-aged women. The factor most influencing was self-efficacy related exercise at 37.9% of the variance. Conclusion: We can conclude that self-efficacy, affect, perceived barriers, and the youngest child's education stage should be considered as important factors for developing program of middle-aged women.

An ethnographic research study on experience of identity in Korean multigravidas (경임부의 정체감 경험)

  • Kim, Young-Hee
    • Korean Parent-Child Health Journal
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    • v.4 no.1
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    • pp.19-34
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    • 2001
  • The childbearing process is not only a biological phenomenon of a woman who gives birth to a child but also a sociocultural phenomenon which is reflected on her value, belief in the sociocultural context according to social change and acculturation. The familial relation and sociocultural context in the multigravidas are more complex and intermingled than in the primigravidas. The purpose of this ethnographic research study was to explore the experience of identity from the first trimester of pregnancy to the third trimester of pregnancy in the Korean multigravidas and to understand deeply the perspectives of pregnant women reflected on Korean sociocultural values, beliefs, norms and familial culture. The participants of 10 pregnant women in Seoul, Korea were observed for 10 months from January to October 2000 and interviewed in their homes and comfortable place. Data analysis was accomplished 'line by line method' and significant concepts were classified according to themes, categories, and domains. The results of this study were as follows : The participants experienced 4 categorized subjects : understanding the oneself - mother to be, performing the dual role, drifting the emotion, and living disheartened during pregnancy. The participants were showed universality and diversity pattern in the self understanding process. The universal pattern were 'mother to be' showing maturation, life along family and priority on motherhood between being a mother and a woman. The diverse pattern were taking the dual role in working mothers having the higher self actualized value and personal identity rather than maternal identity, drifting emotion in resigned mothers, and living disheartened in mothers who have two daughters and no son. In conclusion, the Korean multigravidas experienced womanhood as well as motherhood through the self understanding process with familial connections during pregnancy. Therefore it is suggested that if the harmony and the balance between a mother and a woman is accomplished, the woman will lead a healthy and high quality of life. Also, this study sought to confirm the sociocultural factors affecting during pregnancy in the perspectives of the women with children. Therefore, the health care providers have to divert their attention from biomedical perspectives to biocultural perspectives integrating bio-psycho-sociocultural aspects of pregnant women in a clinical setting.

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Molecular Characterization of Echovirus 30-Associated Outbreak of Aseptic Meningitis in Korea in 2008

  • Choi, Young-Jin;Park, Kwi-Sung;Baek, Kyoung-Ah;Jung, Eun-Hye;Nam, Hae-Seon;Kim, Yong-Bae;Park, Joon-Soo
    • Journal of Microbiology and Biotechnology
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    • v.20 no.3
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    • pp.643-649
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    • 2010
  • Evaluation of the primary etiologic agents that cause aseptic meningitis outbreaks may provide valuable information regarding the prevention and management of aseptic meningitis. In Korea, an outbreak of aseptic meningitis caused by echovirus type 30 (E30) occurred from May to October in 2008. In order to determine the etiologic agent, CSF and/or stool specimens from 140 children hospitalized for aseptic meningitis at Soonchunhyang University Cheonan Hospital between June and October of 2008 were tested for virus isolation and identification. E30 accounted for 61.7% (37 cases) and echovirus 6 accounted for 21.7% (13 cases) of all the human enteroviruses (HEVs) isolates (60 cases in total). For the molecular characterization of the isolates, the VP1 gene sequence of 18 Korean E30 isolates was compared pairwise using the MegAlign with 34 reference strains from the GenBank database. The pairwise comparison of the nucleotide sequences of the VP1 genes demonstrated that the sequences of the Korean strains differed from those of lineage groups A, B, C, D, E, F, and G. Reconstruction of the phylogenetic tree based on the complete VP1 nucleotide sequences resulted in a monophyletic tree, with eight clustered lineage groups. All Korean isolates were segregated from other lineage groups, thus suggesting that the Korean strains were a distinct lineage of E30, and a probable cause of this outbreak. This manuscript is the first report, to the best of our knowledge, of the molecular characteristics of E30 strains associated with an aseptic meningitis outbreak in Korea, and their respective phylogenetic relationships.

Effects of Long-term Fluoride in Drinking Water on Risks of Hip Fracture of the Elderly: An Ecologic Study Based on Database of Hospitalization Episodes (수돗물 불소화와 노령 인구의 고관절 골절에 대한 생태학적 연구)

  • Park, Eun-Young;Hwang, Seung-Sik;Kim, Jai-Yong;Cho, Soo-Hun
    • Journal of Preventive Medicine and Public Health
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    • v.41 no.3
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    • pp.147-152
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    • 2008
  • Objectives : Fluoridation of drinking water is known to decrease dental caries, particularly in children. However, the effects of fluoridated water on bone over several decades are still in controversy. To assess the risk of hip fracture related to water fluoridation, we evaluated the hip fracture-related hospitalizations of the elderly between a fluoridated city and non-fluoridated cities in Korea. Methods : Cheongju as a fluoridated area and Chungju, Chuncheon, Suwon, Wonju as non-fluoridated areas were chosen for the study. We established a database of hip fracture hospitalization episode based on the claims data submitted to the Health Insurance Review Agency from January 1995 to December 2002. The hip fracture hospitalization episodes that satisfied the conditions were those that occurred in patients over 65 years old, the injuries had a hip fracture code (ICD-9 820, ICD-10 S72) and the patients were hospitalized for at least 7days. A total of 80,558 cases of hip fracture hospitalization episodes were analyzed. Results : The admission rates for hip fracture increased with the age of the men and women in both a fluoridated city and the non-fluoridated cities (p<0.01). The relative risk of hip fracture increased significantly both for men and women as their age increased. However, any difference in the hip fracture admission rates was not consistently observed between the fluoridated city and the non-fluoridated cities. Conclusions : We cannot conclude that fluoridation of drinking water increases the risk of hip fracture in the elderly.

Hand Hygiene Compliance among Visitors at a Long-term Care Hospital in Korea: A Covert Observation Study

  • Jung, Min Young;Kang, JaHyun
    • Research in Community and Public Health Nursing
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    • v.30 no.1
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    • pp.99-107
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    • 2019
  • Purpose: This study aimed to assess hand hygiene (HH) compliance among visitors at a long-term care hospital in South Korea. Methods: The study was conducted at a 502-bed long-term care hospital located in Gyeonggi-do Province. From July 1 to August 15, 2017, including more than 6 weekends and one holiday, a trained observer covertly assessed visitors' HH at all five units (360 beds in total) of the study hospital building until the completion of 1,000 HH opportunities (i.e., 200 opportunities per unit). The modified World Health Organization (WHO) HH observation form was used. Instead of professional categories and the "before clean/aseptic procedure" moment, the estimated age range for each visitor were recorded in four categories: children (<14 years old), adolescents (14~18), adults (19~64), and the elderly (${\geq}65$). The collected data were analyzed using SPSS 22.0. Results: A total of 1,000 HH opportunities were observed from 766 visitors (an average of 1.31 per visitor) and the overall HH compliance rate was 20.3%. Overall, 53.7% of the HH cases were performed with soap and water. Among the 4 HH moments, the "after body fluid exposure risk" moment showed the highest compliance rate (83.5%); 93.9% used soap and water. The most commonly exposed potential body fluid among visitors was saliva (48.1%). Conclusion: For hospital visitors in long-term care hospitals, HH education programs including HH moments need to be developed and implemented. Further studies are necessary to evaluate visitors' HH compliance in various hospital settings and find the related variables influencing visitors' HH.

A comparative study of subjective oral symptom experiences according to gender in adolescents of multi-cultural families (다문화가족 청소년의 성별에 따른 주관적 구강증상경험의 비교 연구)

  • Park, Ji-Young;Jung, Gi-Ok
    • Journal of Korean society of Dental Hygiene
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    • v.19 no.2
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    • pp.287-295
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    • 2019
  • Objectives: The purpose of this study was to investigate the factors affecting subjective oral symptoms according to the gender of youth from multi-cultural families in Korea using data from the 14th (2018) Korean Youth Health Behavior Survey. Methods: The independent variables used in this study consisted of gender and sweet drink intake. The dependent variable was experience of subjective oral symptoms. Compensation variables consisted of general characteristics of school type, academic performance, economic status, drinking status, smoking status, and number of tooth brushings day before. The subjects of the study were 835 children of multi-cultural families whose parents were foreigners. All statistical analyses were performed by complex samples cross-tabulation analysis and complex samples logistic regression analysis. Statistical analysis was performed using the PASW statistical package 21.0 (Statistical Packages for Social Science Inc., Chicago, IL, USA). A significance level of 0.05 was used for statistical significance. Results: The composite sample logistic regression analysis showed that there was a statistically significant difference between gender and intake of sweet drinks in experience of subjective oral symptoms. Conclusions: These results suggest that factors influence subjective oral symptoms in Korean multi-cultural adolescents. Therefore, I hope that they will be used as basic data for the introduction and development of a customized oral health education program for improving oral health of multi-cultural adolescents.

Knowledge on complementary foods of mothers with young children and their perception of convenience complementary foods (영·유아 어머니의 이유식 지식수준 및 간편 이유식에 대한 인식)

  • Yoojeong Joo;Jihyun Yoon;Linxi Huang;Youngmin Nam
    • Korean Journal of Community Nutrition
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    • v.29 no.1
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    • pp.16-33
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    • 2024
  • Objectives: The purpose of this study was to examine mothers' knowledge levels on complementary foods and their perception of convenience complementary foods. Methods: An online survey was conducted with mothers aged 20-49 years who had purchased convenience complementary foods and had a preschool child aged 4 months or older. The respondents were categorized into 3 groups based on their knowledge scores: low- (0-50 points), mid- (55-65 points), and high- (70-100 points) knowledge groups. Results: The average score of mothers' knowledge on complementary foods was 58.8 out of 100 points. Working mothers were found to have lower levels of knowledge compared to mothers who were housewives. Only 1/4 of responding mothers had educational experience on complementary foods. Mothers expressed a desire for information on the types of complementary foods (72.2%) and the intake amounts (60.3%) corresponding to each phase of their child's development. Multivariate analysis of variance revealed significant differences in health (P = 0.002), variety (P = 0.039), and hygiene (P = 0.041) among the factors taken into consideration when purchasing convenience complementary foods according to the mothers' knowledge levels. Mothers in the high-knowledge group placed a greater importance on 'balanced nutrition' (P = 0.022) and 'hygienic cooking' (P = 0.010) compared to mothers in the low-knowledge group. The results of the modified importance-performance analysis, which compared the importance and performance of the factors taken into consideration when purchasing convenience complementary foods, highlighted the need for efforts in 'health,' 'hygiene,' and 'price,' while also indicating an excessive effort in 'convenience.' Conclusions: This study suggests expanding relevant education programs to enhance mothers' knowledge on complementary foods, especially for working mothers. In the industry, marketing strategies for complementary food products could be developed that align with the needs of mothers, focusing on health, hygiene, and price.

Total sugar intake and its contributed foods by age groups in Koreans using the 8th (2019-2021) Korea National Health and Nutrition Examination Survey: a cross-sectional study

  • Hyejin Yu;Sang-Jin Chung
    • Korean Journal of Community Nutrition
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    • v.29 no.3
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    • pp.222-233
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    • 2024
  • Objectives: This study was conducted to investigate the status of total sugar intake and contributing foods in Korea according to age groups. Methods: This study used 24-hour dietary recall data from the 8th Korea National Health and Nutrition Examination Survey (2019-2021) to investigate the nutritional and total sugar intake status among Koreans. A total of 18,338 research participants (≥3 years old) were included in this study. To analyze the types of foods contributing to total sugar intake, these foods were categorized into 15 types. Moreover, we examined the total sugar intake and ranked the most consumed foods by age groups (3-11 years, 12-18 years, 19-34 years, 35-49 years, 50-64 years, over 65 years). A survey procedure was employed for statistical analysis. Results: The energy intake ratio from total sugars was approximately 12%-15%, which was within the recommended range. However, the proportion of individuals consuming total sugar exceeding 20% of their total caloric intake is nearly 20%, raising concerns about excessive sugar consumption. Furthermore, the percentage of participants whose intake of sugar from processed foods exceeded 10% of their total calories was highest in the 12-18 age group at 37.1%, followed by the 3-11 age group at 35.2%, and the 19-34 age group at 34.0%. Carbonated drinks, cola, and cider were the primary foods consumed by children and adolescents (3-18 years old) and young adults (19-34 years old). For middle-aged and older adults, mixed coffee with sugar and cream was a prominent contributor to sugar intake. Conclusions: This study investigated sugar consumption patterns among Koreans, finding the principal foods contributing to this intake. Identifying these contributors is pivotal, given their potential impact on public health.