• Biomedical Science Letters
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• v.24 no.1
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• pp.9-14
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• 2018

Ki-67 has been widely performed and become an important biomarker in worldwide clinics, but the standard cut off value of Ki-67 index in breast cancer is still controversy. The objective study was to understand the Ki-67 in breast cancer subtypes and to investigate relative risk of breast cancer subtypes according to Ki-67 cut off value in Korean breast cancer. Immunohistochemical staining (IHC) for estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and Ki-67 index was examined from 123 breast cancer patients. Ki-67 index was significantly overexpressed in PR, ER, and HER2 hormone negative groups. Ki-67 index in Triple negative and HER2 subtypes was shown significantly higher than that in Luminal A and Luminal B subtype. Then, we compared the relative risk of each subtype according to 14% and 20% Ki-67 cut off value, which were applied in most clinics. Especially, 20% Ki-67 cut off value in HER2 and Triple negative subtypes was shown 8.41 fold and 2.83 fold higher relative risk than this in Luminal A subtype. Moreover, Ki-67 index in HER2 2+ or 3+ status showed significantly overexpressed than this in HER2 1+ status. At the 20% Ki-67 cut off value, HER2 1+ or 2+ status and 3+ status showed significant difference. Therefore, the 20% Ki-67 cut off value will be useful as a precise prognostic management and helpful for interpreting diverse outcomes of other subtypes in breast cancer patients.

• Journal of Korean Public Health Nursing
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• v.8 no.1
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• pp.63-72
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• 1994

The purpose of this study was to estimate the industrial worker's knowledge, attitude, and practice about occupational health and to provide the basic data for the development of industrial health services. The study was undertaken from January 15 to January 30, 1993. 549 industrial workers at the Industrial Complex located in Chonbuk Province were participated in this study. The results were as follows; 1. The Knowledge, Attitude and Practice leveles of Workers about Occupational Health. The levels were measured by five point scale. The mean score of knowledge was 2. 59 point out of 4. The mean score of attitude was 2.37 point out of 4. The mean score of practice was 2. 38 point out of 4. 2. The analysis of their knowledge" attitude, and practice about general characteristics. 1) There was significant difference among different age groups. $(P{\leqq}0.0001)$ -. The group of age 25-29 was the highest value in knowledge and attitude. -. The group of age over 50 was highest value in practice. 2) There was significant difference between sexual groups in all items. -. Male workers were higher than Female workers in all items. (P=0.0000) 3) There was significant difference according to the marital status in all items. -. Married workers were higher than Single workers in all items. (P = 0.0000) 4) There was significant difference among different groups of educational level in attitude and practice. (P<0.05) The value was positivly correlated to their educational level. 5) There was significant difference among the groups of job-part in knowledge and practice. (P=0.000, P=0.031) -. Office workers were higher than Production workers in all items. 6) There was significant difference among different group of job experience in knowledge and attitude. (P=0.0000. P=0.0387) The value was positively correlated to the years length of job experience. 7) There was significant difference among the groups of different monthly income in all items. (P=0.000) The value was positively correlated to their monthly income.

• Journal of Korean Society on Water Environment
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• v.27 no.3
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• pp.364-370
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• 2011

Water quality criteria for human health protection are derived based on the human health risk assessment. Water quality criteria in Korean freshwater bodies have been derived according to the equations developed by the US Environmental Protection Agency. The equations include the fish intake parameter, which is very important factor that significantly influences on the criteria derivation. So far, several fish intake values were used in human health risk assessment for water quality standards and effluent standards. However, these values are not consistent and they refer to various sources. Therefore, there is a need to suggest the most appropriate value of fish intake parameter to derive freshwater quality criteria in Korea. In this study, national and international fish intake values were widely collected and evaluated to select the adequate value of fish intake parameter that can be applied in Korea. The USEPA presented fish intake parameter as the 17.5 g/day for general adults and sport fishers and 142.4 g/day for subsistence fishers. In Korean reports, wide range values of 2 to 67.7 g/day were suggested as fish intake value. These values included finfish and shellfish intakes in common but had various habits. This study found that the 52.4 g/day suggested in Korean Exposure Factors Handbook published by the Ministry of Environment in 2007 seemed to be the suitable fish intake parameter to derive the freshwater quality criteria in Korea. The value is based on water corrected intakes of finfish and shellfish present in freshwater and coastal areas. We expect that this report can be useful to select suitable fish intake value in human health risk assessment for establishing freshwater quality standard in Korea.

• Health Policy and Management
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• v.31 no.4
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• pp.491-507
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• 2021

Background: This study aims to measure regional healthcare differences in Korea, and define relatively underserved areas. Methods: We employed position value for relative comparison index (PARC) to measure the healthcare status of 250 areas using 137 indicators in five following domains: healthcare demand, supply, accessibility, service utilization, and outcome. We performed a sensitivity analysis using t-SNE (t-distributed stochastic neighboring embedding). Results: Based on PARC values, 83 areas were defined as relatively underserved areas, 49 of which were categorized as moderate and 34 as severe. The provincial regions with the most underserved areas were Gyeongbuk (16 areas), Gangwon (13), Jeonnam (13), and Gyeongnam (12). Conclusion: This study suggests a relative comparison approach to define relatively underserved areas in healthcare. Further studies incorporating various perspectives and methods are required for policy implications.

• The Journal of the Korea Contents Association
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• v.22 no.1
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• pp.611-619
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• 2022

This study utilized the data from 2017, 2019 Korean National Health and Nutrition Survey to analyze the factors influencing depression and suicidal ideation among single-person households. For the analysis, demographic and economic variables as well as health status/behavior variables were considered. Activity restriction (OR: 4.753, p-value: <.0001) and smoking status (OR: 2.013, p-value: 0.044) were significantly associated with depression, and in terms of suicidal ideation, household income (OR: 3.526, p-value: 0.043), subjective health status (OR: 2.945, p-value: 0.007), activity restriction (OR: 2.263, p-value: 0.003) and smoking status (OR: 2.000, p-value: 0.023) showed significant association. In this regard, single-person households are likely to experience psychological angst, and further experience mental problems due to socio-economic and physical crisis. Therefore, it is necessary to establish a social network system in the community to detect those in need and provide appropriate interventions to prevent harmful outcomes.

• Quality Improvement in Health Care
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• v.17 no.1
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• pp.5-20
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• 2011

• Journal of Korean society of Dental Hygiene
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• v.9 no.4
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• pp.836-848
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• 2009

Objectives : This study was conducted to evaluated the subjective oral health state related periodontal disease of elderly people. Methods : Data were collected through the National Health and Nutrition Survey in 2005. Participants consisted of 1,091 elderly people above 65 years old. Independent variables in the survey were social characteristic, health behavior, oral health condition, oral health management. The data were analyzed by using the SPSS 12.0. Results : The more elderly people of 69.0% recognized own oral health as is not healthy, elderly people of 74.0% recognized own oral health as is not healthy about subjective oral health and a lot of stressed(82.8%) has felt highly about periodontal disease(p<0.001). Respondents of have a sound teeth(58.9%), have a lower denture(75.0%) and have a no problem in mastication(74.5%) has felt highly about periodontal disease(p<0.001). Elderly people recognized own oral health as is not healthy about subjective oral health were 0.316 times(p<0.01), elderly people recognized own oral health as is common healthy about subjective oral health were 0.241 times(p<0.001), a lot of stressed were 1.410 times has felt highly about periodontal disease. Elderly people of have a lower denture were 1.159 times, have a upper denture were 1.159 times, have a lower and upper denture were 0.464 times has felt highly about periodontal disease(p<0.05). Also respondents of have a no problem in mastication were 7.464 times compared with problem in mastication(p<0.001). Conclusions : Quality of life from disease of Korean elderly people can be fallen, and improve quality of life that medical treatment is healthy numerical value state numerical value state. Study's findings of above may be used to inform the importance of health numerical value state while establish dental health policy that is string.

• Journal of Preventive Medicine and Public Health
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• v.48 no.1
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• pp.18-27
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• 2015

Objectives: Civic participation, that which directly influences important decisions in our personal lives, is considered necessary for developing a society. We hypothesized that civic participation might be related to self-rated health status. Methods: We constructed a multi-level analysis using data from the World Value Survey (44 countries, n=50 859). Results: People who participated in voting and voluntary social activities tended to report better subjective health than those who did not vote or participate in social activities, after controlling for socio-demographic factors at the individual level. A negative association with unconventional political activity and subjective health was found, but this effect disappeared in a subset analysis of only the 18 Organization for Economic Cooperation and Development (OECD) countries. Moreover, social participation and unconventional political participation had a statistically significant contextual association with subjective health status, but this relationship was not consistent throughout the analysis. In the analysis of the 44 countries, social participation was of borderline significance, while in the subset analysis of the OECD countries unconventional political participation was a stronger contextual determinant of subjective health. The democratic index was a significant factor in determining self-rated health in both analyses, while public health expenditure was a significant factor in analysis of 18 countries. Conclusions: Our investigation suggests that civic participation, including unconventional political activity at the contextual level, might be a significant determinant of health status of a country.

• The Korean Journal of Health Service Management
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• v.7 no.3
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• pp.57-69
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• 2013

In these days, the interest on health industry is increasing around the world. This paper attempts to estimate the economic effects of the Cosmetic Industrydusing the Input-Output Analysis. Especially, 78*78 Sector Tables were used as the first analysis tool. So then, 79*79 Sector Tables adjusted were used for that industry. The main analysis tools of this study are comparing and analyzing backward and forward linkage effects, the induced effects of the self industry and other industries and the induced coefficients such as product, value-added, job and employment. According to the result of analysis, the cosmetic industry has great economic impacts which affects the major macroeconomic factors such as product, value added and backward linkage effect. And the induced effects of the self cosmetic industry are significant compared to other industries in aspects of product, value-added, and employment.

• The Korean Journal of Health Service Management
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• v.7 no.3
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• pp.225-235
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• 2013

This study purposed to analyze the productivity of regional medical capacity in attracting medical tourist between 2009 and 2011. Data envelopment analysis (DEA) and Malmquist productivity index (MPI) were applied to test the productivity and changes in study periods. The DEA model included a number of doctors, nurses, and beds as input factors, and a number of inpatient and outpatient, and hospital income as output factors. The result of the study were as follow. Jeju had efficiency value of 1 for three years. Seoul, Busan, Daegu, Daejeon, Ulsan, Gyeonggi, Gangwon, Jeonnam, Gyeongbuk, and Gyeongnam showed an increasing trend of efficiency value over three years. Seoul had the efficiency value, 1, in 2011. But, Incheon, Gwangju showed decreasing efficiency score during the study period. MPI showed overall productivity decrease during the period. Further studies will be needed by collecting more time-series data.