• PNF and Movement
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• 제20권1호
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• pp.135-145
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• 2022

Purpose: The purpose of this study was to investigate the association between cognitive and motor inhibition by comparing muscle activity and ground reaction force during unplanned gait termination according to reaction time measured through the stop-signal task. Methods: Sixteen young adults performed a stop-signal task and an unplanned gait termination separately. The subjects were divided into fast and slow groups based on their stop-signal reaction time (SSRT), as measured by the stop-signal task. Electromyography (EMG) and ground reaction force (GRF) were compared between the groups during unplanned gait termination. The data for gait termination were divided into three phases (Phase 1 to 3). The Mann-Whitney U test was used to compare spatiotemporal gait parameters and EMG and GRF data between groups. Results: The slow group had significantly higher activity of the tibialis anterior in Phase 2 and Phase 3 than the fast group (p <0.05). In Phase 1, the fast group had significantly shorter time to peak amplitude (TPA) of the soleus than the slow group (p <0.05). In Phase 2, the TPA of the tibialis anterior was significantly lower in the fast group than the slow group (p <0.05). In Phase 3, there was no significant difference in the GRF between the two groups (p >0.05). There were no significant difference between the two groups in the spatiotemporal gait parameters (p >0.05). Conclusion: Compared to the slow group, the fast group with cognitive inhibition suppressed muscle activity for unplanned gait termination. The association between SSRT and unplanned gait termination shows that a participant's ability to suppress an incipient finger response is relevant to their ability to construct a corrective gait pattern in a choice-demanding environment.

• 한국자기공명학회논문지
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• 제24권2호
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• pp.53-58
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• 2020

Free radicals including reactive oxygen species (ROS) are important chemicals in the research area of biology, pharmaceutical, medical, and environmental science as well as human health risk assessment as they are highly involved in diverse metabolism and toxicity mechanisms through chemical reactions with various components of living bodies. Electron spin resonance (ESR) spectroscopy is a powerful tool for detecting and quantifying those radicals in biological environments. In this work we observed the ESR signal of 2,2,6,6-Tetra-methyl piperidine 1-oxyl (TEMPO) in aqueous solution at various concentrations to estimate the uncertainty factors arising from the experimental conditions and signal treatment methods. As the sample position highly influences the signal intensity, dual ESR tube geometry (consists of a detachable sample tube and a position fixed external tube) was adopted. This type of measurement geometry allowed to get the relative uncertainty of signal intensity lower than 1% when triple measurements are averaged. Linear dependence of signal intensity on the TEMPO concentration, which is required for the quantification of unknown sample, could be obtained over a concentration range of ~10³ by optimizing the signal treatment method depending on the concentration range.

• Smart Structures and Systems
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• 제1권2호
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• pp.185-215
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• 2005

Advanced signal processing techniques have been long introduced and widely used in structural health monitoring (SHM) and nondestructive evaluation (NDE). In our research, we applied several signal processing approaches for our embedded ultrasonic structural radar (EUSR) system to obtain improved damage detection results. The EUSR algorithm was developed to detect defects within a large area of a thin-plate specimen using a piezoelectric wafer active sensor (PWAS) array. In the EUSR, the discrete wavelet transform (DWT) was first applied for signal de-noising. Secondly, after constructing the EUSR data, the short-time Fourier transform (STFT) and continuous wavelet transform (CWT) were used for the time-frequency analysis. Then the results were compared thereafter. We eventually chose continuous wavelet transform to filter out from the original signal the component with the excitation signal's frequency. Third, cross correlation method and Hilbert transform were applied to A-scan signals to extract the time of flight (TOF) of the wave packets from the crack. Finally, the Hilbert transform was again applied to the EUSR data to extract the envelopes for final inspection result visualization. The EUSR system was implemented in LabVIEW. Several laboratory experiments have been conducted and have verified that, with the advanced signal processing approaches, the EUSR has enhanced damage detection ability.

• 한국복합재료학회:학술대회논문집
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• 한국복합재료학회 2005년도 춘계학술발표대회 논문집
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• pp.25-28
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• 2005

The optical fiber is known for the proper sensor which can accomplish the structural health monitoring, Fiber Bragg Grating sensors are being studied more than any other fiber optic sensors due to good multiplexing capabilities. But because the signal stability of FBG sensors can be influenced by the strain gradient, it needs to analyze signal of FBG sensors. Particularly acoording to strain gradient induced by structural geometry or cracks, the spectrum peak of the FBG sensor signal can be split easily. In this paper, the spectrum analysis of the FBG sensor signal was performed and the region of embedment of FBG sensors was determined in $H_2$ pressure vessel by numerical method.

• BMB Reports
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• 제37권4호
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• pp.480-486
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• 2004

Brain ischemia brings about hypoxic insults. Hypoxia is one of the major pathological factors inducing neuronal injury and central nervous system infection. We studied the involvement of mitogen-activated protein (MAP) kinase in hypoxia-induced apoptosis using cobalt chloride in C6 glioma cells. In vitro cytotoxicity of cobalt chloride was tested by MTT assay. Its $IC_{50}$ value was $400\;{\mu}M$. The DNA fragment became evident after incubation of the cells with $300\;{\mu}M$ cobalt chloride for 24 h. We also evidenced nuclear cleavage with morphological changes of the cells undergoing apoptosis with electron microscopy. Next, we examined the signal pathway of cobalt chloride-induced apoptosis in C6 cells. The activation of extracellular signal-regulated protein kinase 1/2 (ERK 1/2) started to increase at 1 h and was activated further at 6 h after treatment of 400 M cobalt chloride. In addition, pretreatment of PD98059 inhibited cobalt chloride-induced apoptotic cell morphology in Electron Microscopy. These results suggest that cobalt chloride is able to induce the apoptotic activity in C6 glioma cells, and its apoptotic mechanism may be associated with signal transduction via MAP kinase (ERK 1/2).

• 전기학회논문지
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• 제61권9호
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• pp.1350-1357
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• 2012

Medical system for personal health management recently changes its paradigm from hospital service to self home care based on ubiquitous technology for healthcare anywhere at any time. The present study developed a wireless bio-signal measurement system for patients to self manage pulmonary disease and benign prostate hyperplasia(BPH), both of which are chronic diseases with increasing frequency in modern society. Velocity-type respiratory air flow transducer adapted to develop respiratory module for pulmonary disease management was simplified in structure to measure uni-directional flow since most important diagnostic parameters are evaluated on the expiratory flow signal only. Standard weight measurement technique was introduced to obtain urinary flow signal for BPH management. Three load cell signals were acquired for averaging to minimize noise, followed by accuracy evaluation. Transmission and receiver modules were also developed with user program for wireless communication. Averaged relative errors were 2.05 and 1.02% for respiratory volume and maximal flow rate, respectively, and the relative error was 2.17% for urinary volume, demonstrating that both modules enabled very accurate measurements. Wireless communication distance was verified within 15m, long enough for home care application. The present system allows the user to select a necessary measurement module on a particular health demand and to immediately provide the self-test results, thus better quality health care would be possible.

• 대한임상전기생리학회지
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• 제10권2호
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• pp.7-14
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• 2012

Purpose : This study investigated the validity of crosswalk signal time length with regards to elderly stroke patients. Methods : We recruited 60 elderly adults sixty years of age or older for our study. The participants were divided into three groups.Group A consisted of 20 healthy participants with no walking aids. Group B consisted of 20 stroke patients with no walking aids. Group C consisted of 20 stroke patients using a cane as a walking aid. We measured the walking times of participants for 7 m, 14 m and 21 m lengths. Results : Using an independent t test, there was a statistically significant difference in the walking times between Group A and Group B for all lengths. There was a statistically significant difference in the walking times between Group A and Group C for all lengths. There was no statistically significant difference in the walking times between Group B and Group C. There was a statistically significant difference between the three group when using ANOVA. Conclusion : From the results of this study, we infer that the signal times at crosswalks are inappropriate for elderly stroke participants who use a cane as a walking aid. Therefore further research should be conducted to determine the appropriate amount of additional time needed for the elderly to safely cross the street.

• Safe Food
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• 제3권4호
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• pp.12-17
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• 2008

• 대한약리학회:학술대회논문집
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• 대한약리학회 2006년도 The 6th Congress of the Federation of Asian and Oceanian Physiological Societies
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• pp.109.2-109.2
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• 2006

• 한국전문물리치료학회지
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• 제20권2호
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• pp.28-37
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• 2013

This study examined differences in the activity of upper limb muscles according to how an ultrasound head is gripped. Twenty-two adult males were participated in the study. Each participant was asked to apply ultrasound treatment on to a lump of pork meat by two different ultrasound head grip patterns: spherical and cylindrical grips. Muscle activity was measured in the extensor carpi radialis longus (ECRL), flexor carpi ulnaris (FCU), and pronator teres (PT), triceps brachii (TB), middle deltoid (MD), and upper trapezius (UT) muscles. There were no significant differences in the EMG signals of any muscle according to the ultrasound head grip pattern (p>.05). There were significant differences in the EMG signal of each type of muscle (p<.05). The EMG signal of UT was the lowest and that of TB was lower than ECRL and FCU. There were interactions between ECRL and FCU, between ECRL and PT, between FCU and ECRL, and between FCU and MD. The EMG signal of ECRL using the cylindrical head was low and that of FCU with the cylindrical head was high, while the opposite was the case with the spherical head ($p_{adj}$ <.05/15). The results of this study indicate that the wrist muscles worked actively when the participants applied ultrasound therapy using both spherical and cylindrical heads. A spherical head might induce imbalanced muscle activity among the wrist muscles, leading to deviation of the wrist joint. Therefore, the cylindrical head is recommended for ultrasound therapy because it produced a constant, repeated force.