• Journal of fish pathology
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• v.22 no.2
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• pp.147-153
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• 2009

To study the biological activity of interleukin-$1\beta$(IL-$1\beta$), a proinflammatory cytokine, in nile tilapia, Oreochromis niliticus, the recombinant tilapia IL-$1\beta$ was produced in E. coli cells based on pQE vector. Ni-NTA (nitriloacetic acid) metal affinity chromatography was used to purify recombinant protein. The eluted fractions exhibited a single band of protein with a molecular weight of about 25kDa, which is in close agreement with 25.4 kDa predicted by the cDNA sequence. The biological activity of the purified recombinant tilapia IL-$1\beta$ was tested through its effects on IL-$1\beta$ gene expression, which are known as IL-$1\beta$ inducible genes in mammals and fishes. IL-$1\beta$ gene expression induced by poly I:C, a synthetic double stranded RNA, was also assessed in tilapia head kidney cells. IL-$1\beta$ gene expression was analysed using QPCR (quantitative polymerase chain reaction). The ratio of the indicated gene expression was expressed as the relative mRNA level to $\beta$-actin mRNA level, which is constitutively expressed in macrophages. Consequently, head kidney cells incubated for three hours with rIL-$1\beta$(10, 2, 1 $\mu{g}$/ml) showed a dose dependent increase in IL-$1\beta$ mRNA levels and 1 $\mu{g}$/ml of poly I:C was also able to induce IL-$1\beta$ gene expression in head kidney in tilapia.

• Journal of the Society of Naval Architects of Korea
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• v.46 no.4
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• pp.373-381
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• 2009

The running attitude of a high-speed planing craft may change significantly depending on its speed in seaway. Other variables that may influence its running attitude are its weight, center of gravity, sea conditions, and so on. In this paper, planing craft model tests were carried out with respect to above variables in SNU towing tank, and vertical motion responses of a planing craft in regular head waves were analyzed. The experimental results in regular waves were compared with those in calm water, and compared with the theoretical estimations. Finally, the effects of running speeds of a planing craft on its motion amplitudes are confirmed.

• The Korean Journal of Pain
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• v.34 no.4
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• pp.375-393
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• 2021

Percutaneous osteoplasty (POP) is defined as the injection of bone cement into various painful bony lesions, refractory to conventional therapy, as an extended technique of percutaneous vertebroplasty (PVP). POP can be applied to benign osteochondral lesions and malignant metastatic lesions throughout the whole skeleton, whereas PVP is restricted to the vertebral body. Common spinal metastases occur in the thoracic (70%), lumbosacral (20%), and cervical (10%) vertebrae, in order of frequency. Extraspinal metastases into the ribs, scapulae, sternum, and humeral head commonly originate from lung and breast cancers; extraspinal metastases into the pelvis and femoral head come from prostate, urinary bladder, colon, and uterine cervical cancers. Pain is aggravated in the dependent (or weight bearing) position, or during movement (or respiration). The tenderness and imaging diagnosis should match. The supposed mechanism of pain relief in POP is the augmentation of damaged bones, thermal and chemical ablation of the nociceptive nerves, and local inhibition of tumor invasion. Adjacent (facet) joint injections may be needed prior to POP (PVP). The length and thickness of the applied needle should be chosen according to the targeted bone. Bone cement is also selected by its osteoconduction, osteoinduction, and osteogenesis. Needle route should be chosen as a shortcut to reach the target bony lesions, without damage to the nerves and vessels. POP is a promising minimally invasive procedure for immediate pain relief. This review provides a technical survey for POPs in painful bony lesions.

• Journal of the Korean Society of Costume
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• v.58 no.3
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• pp.105-115
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• 2008

A Go-go-kwan is a particular hat which has worn by married woman in Mongol and Yuan dynasty in China. It is also widely called as a Boktak in Mongol. The Go-go-kwan, recorded in jip-sa and in the miniature painting of 14th century is the early type of go-go-kwan. Later type can be seen from the relic collections of Gyeonggi Provincial Museum in Korea. The Go-go-kwan is composed with three parts ; feather part, tube part and hat part. Among the feathers, the largest one is as long as four times of the length of the tube and the shortest one is half the length of the tube. The tube is made of light weight wood such as white birch or bamboo, and covered with silk. Some of the hats were made exactly to fit on the head whereas others were designed to wear on the head as like jobawi.

• Korean Journal of Clinical Pharmacy
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• v.26 no.4
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• pp.269-282
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• 2016

Venous thromboembolism, encompassing deep vein thrombosis and pulmonary embolism, has increased in cancer patients and adversely affects their prognosis. Low-molecular-weight heparins are recommended as efficacious and safe anticoagulation treatment in cancer patients. However, in practice, oral anticoagulation is preferred, especially if longterm or extended treatment is necessary. Novel oral anticoagulants have recently emerged as an alternative to the standard therapy owing to the ease of administration, predictable anticoagulation effect without the need of laboratory monitoring, and fewer drug interactions. These new agents have been shown as effective and safe for the management of cancer-associated thrombosis in ongoing head-to-head comparative trials. Here we review the advances and limitation of current anticoagulant therapies.

• Sleep Medicine and Psychophysiology
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• v.12 no.2
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• pp.98-104
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• 2005

Approximately 1% to 3% of all children have obstructive sleep apnea syndrome (OSAS). OSAS in children can lead to a variety of symptoms and sequalae; impairment of development and quality of life, behavioral and personality disturbance, learning problem, cor pulmonale and hypertension. Diagnosis and treatment of OASA for children are different from those for adults in many respects. Adenotonsillar hypertrophy is major cause of childhood OSAS. Overnight polysomnography in a sleep laboratory is the gold standard for diagnosing childhood OSAS. However, because full polysomnography in children may be difficult to obtain, expensive, and inconvenient, other methods to diagnose OSAS have been investigated. Adenotonsillectomy is the most common surgical treatment of childhood OSAS. But if residual symptoms remained after adenotonsillectomy, it should be considered to additional treatment such as weight control, sleep positional change, and continuous positive airway pressure (CPAP).

• Proceedings of the KIEE Conference
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• 2003.07d
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• pp.2411-2413
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• 2003

A new small humanoid robot system is developed in this paper. The humanoid robot has total 20 DOFs : 6 DOFs in each legs, 3 DOFs in each arms, and 2 DOFs in head, 34cms in height, and 2kgs in weight. The robot has the following characteristics: (1) PDA as host controller (2) network-based joint controller (3) wireless camera attached in robot's head (4) mechanism design by CATIA and high speed laser prototyping (5) graphic MMI(Man-Machine Interface) utilizing the CATIA data. By using ADXL inclination sensor, we implement the rope swing with the robot leg motion as well as walking.

• Journal of the Korean Society for Precision Engineering
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• v.21 no.6
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• pp.179-187
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• 2004

In this study, for a safety assessment of wheelchair occupant in frontal and side impact of wheelchair loaded vehicle, a sled impact test was perfumed. Each test was carried out total 6 times, by using Hybrid III 50th-percentile male dummy in light weight and electric wheelchair. We estimate MC(Motion Criteria), CIC(Combined Injury Criteria), HIC(Head Injury Criteria), HNIC(Head and Neck Injury Criteria) based on measured data. Through this study, we make an assessment of risk analysis of wheelchair occupant and wheelchair. Through this study, safety standard of wheelchair is to be evaluated.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.20 no.12
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• pp.78-84
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• 2021

Reducing the weight of automobiles is a significant global developmental task. Two materials are used to lighten automobiles: aluminum and CFRP frames. Aluminum is a non-ferrous metal, and CFRP is a composite material. They are lighter and harder than other materials. The two materials were used for the collision analysis. Subsequently, the two cases were compared. Three cases were considered for the collision analysis: head-on collision, partial head-on collision, and side collision at a speed of 60 km/h. The three cases were compared and analyzed considering the materials used to understand the difference between aluminum and CFRP and their collision characteristics.

• Asian-Australasian Journal of Animal Sciences
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• v.5 no.2
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• pp.261-266
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• 1992

Yearling replacement heifers were used in a two-year study at the Fort Stanton Experimental Ranch near Capitan, New Mexico, USA to compare frequency (once versus three times weekly) of feeding a cottonseed cake supplement. The study involved periods of 130 days (January 4 through May 14) in 1985, and 146 days (December 4 through April 29) in 1986. In each year, supplemental periods were just before the breeding season (natural breeding in multiple-sire groups) that lasted for 75 days during first year and 60 days during second year. During the first year, all (83) heifers (Angus $\times$ Hereford) were supplemented at a level equivalent to 45 kg/head daily and during second year, all (69) heifers (Angus $\times$ Hereford, Hereford) were fed at a level equivalent to .68 kg/head daily. In the first year, heifers were sorted by initial weight into two replications, i.e., those weighing under 223 kg were placed in replicate 1 and those weighing over 223 kg were placed in replicate 2. During the second year, heifers were sorted by breed into two replications, i.e., Angus $\times$ Hereford heifers were placed in replicate 1 and Hereford heifers in replicate 2. Each year, half of the heifers in each replication were supplemented once weekly and the other half three time weekly. Weight gains of heifers were similar for the two treatments over both years of study. During the first year, weight gains for heifers supplemented once or thrice weekly (.23 vs .21 kg daily, respectively) did not differ (p>.05) and the same trend for the second year (.15 vs .16 kg daily, respectively) was observed. Similarly, breeding performance was consistent with weight gains and no difference (p>.05) between treatments was observed either year. Lower conception rates during the second tear of study (92 vs 72% for years 1 and 2, respectively) were due mainly to involvement of Hereford heifers that had an average weight of 232 kg at the start of breeding season and conception rate of 54% (averaged across both supplemental treatments). Based on the combined results of both trials, frequency of supplementation did not affect growth rate of yearling heifers nor did it influence their subsequent conception rate.