• 응용통계연구
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• 제20권1호
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• pp.39-52
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• 2007

협심증 치료의 신약에 대한 교차계획 임상시험(crossover clinical trials)에서 신약의 효능을 알아보는 운동테스트(treadmill exercise test) 결과는 중도절단 생존시간(censored survival times)으로 측정된다. 이 논문에서는 교차계획에서 수집된 중도절단 생존자료의 여러 가지 분석법에 대해 설명한다. 중도절단을 감안한 비모수적 방법들과 층화 Cox 비례위험모형 (stratified Cox proportional hazards model)에 근거한 분석법이 제시되었다. 한편, 교차계획의 두 시기에 걸쳐 수집된 생존시간의 차(difference)로부터 구간절단자료(interval censored data)가 생성되며 이에 근거한 분석법으로서 이 논문에서는 구간절단자료에 대한 Cox 비례위험모형 (proportional hazards model)의 가능성을 알아보며, 예제 자료로써 여러 방법들의 결과를 비교해 본다.

• 한국화재소방학회논문지
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• 제15권2호
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• pp.20-30
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• 2001

The science and technology of seismic hazard mitigation are increasingly being shared among scientists and policy makers around the world. Administrative expertise is also being shared. While there is still tremendous unevenness in technical and administrative capacities and resources, a global community of emergency managers is developing and there is a globalization of expertise. Hazards are better understood, tools for risk assessment are improving, techniques for hazard mitigation are being perfected, and communities and states are implementing more comprehensive disaster preparedness, response, and recovery programs. Priorities are also emerging and hazard mitigation has emerged as the priority of choice in North America and Europe. An increasingly important component of hazard mitigation is resilience, in terms of increased capacities for disaster mitigation and recovery at the community and even individual levels. Each year, more is known about the locations and natures of seismic hazards, although there are still unknown and poorly understood fault lines and limited understanding of related disasters such as tsunamis and landslides. More is known about the impact of earthquakes on the built environment, although nature still provides surprises to confound man's best extorts to reduce risk. More is known about human nature and how people respond to uncertain risk and when confronted by certain catastrophe. However, despite the increased understanding of seismic phenomena and how to protect people and property, there is much that needs to be done to reduce the risk, particularly in major metropolitan areas.

• Ocean Systems Engineering
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• 제9권3호
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• pp.261-285
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• 2019

Nowadays in offshore industry there are emerging hazards with vague property such as act of terrorism, act of war, unforeseen natural disasters such as tsunami, etc. Therefore industry professionals such as offshore energy insurers, safety engineers and risk managers in order to determine the failure rates and frequencies for the potential hazards where there is no data available, they need to use an appropriate method to overcome this difficulty. Furthermore in conventional risk based analysis models such as when using a fault tree analysis, hazards with vague properties are normally waived and ignored. In other word in previous situations only a traditional probability based fault tree analysis could be implemented. To overcome this shortcoming fuzzy set theory is applied to fault tree analysis to combine the known and unknown data in which the pre-combined result will be determined under a fuzzy environment. This has been fulfilled by integration of a generic bow-tie based risk analysis model into the risk assessment phase of the Risk Management (RM) cycles as a backbone of the phase. For this reason Fault Tree Analysis (FTA) and Event Tree Analysis (ETA) are used to analyse one of the significant risk factors associated in offshore terminals. This process will eventually help the insurers and risk managers in marine and offshore industries to investigate the potential hazards more in detail if there is vagueness. For this purpose a case study of offshore terminal while coinciding with the nature of the Caspian Sea was decided to be examined.

• 한국화재소방학회논문지
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• 제14권3호
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• pp.27-32
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• 2000

산림에 대한 화재 위험성 평가는 산불의 예방, 진화 및 관리에 있어서 우선적으로 고려되어야 할 부분이다. 단일 화재로서는 축내 최대 규모인 1997년 4월에 발생한 강원도 고성산불과 2000년 4월에 발생한 강원도 영동지방 산불은 이러한 화재위험성 평가의 필요성을 절실히 요구하고 있다. 현재 국내에서의 사용하고 있는 위험도의 표현은 기상인자에 의해 연료가 화재에 노출될 수 있는 위험을 나타낸 것으로 습도측정봉 무게 환산식을 통해 산불 발생 위험지수 산정하여 산불경보시스템을 사용하며 나타내고 있다. 앞으로, 지역별 종합적인 산림화재 위험성 평가를 위해서는 주요 인자들의 위험성을 측정하고 통계적 고찰을 통한 위험성 평가를 표현할 필요성이 있다. 이에 본 연구에서는 먼저 통계적 고찰을 통해 발생 빈도와 피해의 심각성을 분석하여 위험성을 평가하였고 수목의 열량적 가치를 시차주사열량계 실험을 통해 분석하여 수목분포도에 따를 열적 상대 위험성을 평가하였다

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 1994년도 교수 연수회(환경)
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• pp.426-430
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• 1994

The assessment of exposure is an important component of the risk assessment process. Exposure information is used in risk assessment in at least two ways: 1) in the identification of hazards and the epidemiologic research investigating exposure-response relationships and 2) in the development of population exposure estimates. In both of these cases, the value of a chemical risk assessment is enhanced by improvements in the quality of exposure assessments. The optimum exposure assessment is the direct measurement of population exposure; however, such measurements are rarely available. Recent developments in methods for exposure assessment allow estimates to be made that are valid representations of actual exposure. The use of these exposure estimates to classify exposures correctly enhances the likelihood that causal associations between exposure and response will be correctly identified and that population risks will be accurately assessed.

• Safety and Health at Work
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• 제9권3호
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• pp.239-248
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• 2018

Background: Workers may be exposed to various types of occupational hazards at the same time, potentially increasing the risk of adverse health outcomes. The aim of this review was to analyze the effects of multiple occupational exposures and coexposures to chemical, biomechanical, and physical hazards on adverse health outcomes among agricultural workers. Methods: Articles published in English between 1990 and 2015 were identified using five popular databases and two complementary sources. The quality of the included publications was assessed using the methodology developed by the Effective Public Health Practice Project assessment tool for quantitative studies. Results: Fifteen articles were included in the review. Multiple chemical exposures were significantly associated with an increased risk of respiratory diseases, cancer, and DNA and cytogenetic damage. Multiple physical exposures seemed to increase the risk of hearing loss, whereas coexposures to physical and biomechanical hazards were associated with an increased risk of musculoskeletal disorders among agricultural workers. Conclusion: Few studies have explored the impact of multiple occupational exposures on the health of agricultural workers. A very limited number of studies have investigated the effect of coexposures among biomechanical, physical, and chemical hazards on occupational health, which indicates a need for further research in this area.

• 한국산업보건학회지
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• 제22권3호
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• pp.235-243
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• 2012

Objectives: The purpose of this study is the work environment management method through risk assessment and investigation of the work place that deals with Ammonium nitrate, based on information in and outside the country. Methods: This study suggests method of work environment management through risk assessment and investigation of the work place that deals with Ammonium nitrate, and finds out cases of Ammonium nitrate causing hazard, danger and health risk, based on literature investigation. Results: Rats exposed repeatedly to $LD_{50}$ 2,217 mg/kg(rat), $LC_{50}$ 88.8 mg/L(rat, skin) which cause high level of skin irritation, reported 1 $mg/m^3$ of NOAEL, while LOAEL was less than 100 mg/kg for the rats orally administered with the $LD_{50}$ 2,217 mg/kg(rat), $LC_{50}$ 88.8 mg/L(rat, skin), for 13 weeks. Domestically 31,640 ton/y of ammonium nitrate has been used in 22 workplace and the result of workplace assessment was 0.0171-0.9983 $mg/m^3$. ADD was 8.77-59.63 ${\mu}g/kg-day$ according to the exposure scenario. In other words the result of the risk assessment goes beyond the 'standard 1'. Conclusions: Ammonium nitrate creates a high level of irritation and toxicity when coming in breathe it or contact with skin, and is classified as category3 of GHS and specific target organ toxicant (irritating respiratory system). Exposure level at work places needs to be maintained under $1mg/m^3$, to prevent workers from being damaged.

• Wind and Structures
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• 제30권1호
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• pp.1-13
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• 2020

The loss prediction and assessment during extreme events such as wind hazards is always crucial for the group low-rise residential buildings. This paper analyses the effect of variation in building density on wind-induced loss for low-rise buildings and proposes a loss assessment method consequently. It is based on the damage matrices of the building envelope structures and the main load-bearing structure, which includes the influence factors such as structure type, preservation degree, building density, and interaction between different envelope components. Accordingly, based on field investigation and engineering experience, this study establishes a relevant building direct economic loss assessment model. Finally, the authors develop the Typhoon Disaster Management System to apply this loss assessment methodology to practice.

• Journal of Advanced Research in Ocean Engineering
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• 제3권3호
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• pp.125-135
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• 2017

The paper considers the practical application of the FMEA(Failure Mode and Effect Analysis) method to assess the operational reliability of the LNG(Liquefied Natural Gas) transfer system, which is a potential problem for the connection between the LNG FPSO and LNG carrier. Hazard Identification (HAZID) and Hazard operability (HAZOP) are applied to identify the risks and hazards during the operation of LNG transfer system. The approach is performed for the FMEA to assess the reliability based on the detection of defects typical to LNG transfer system. FTA and FMEA associated with a probabilistic risk database to the operation scenarios are applied to assess the risk. After providing an outline of the safety assessment procedure for the operational problems of system, safety assessment example is presented, providing details on the fault tree of operational accident, safety assessment, and risk measures.

• 암석학회지
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• 제27권1호
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• pp.49-66
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• 2018

화산위험지도 작성은 1960년대 과학 탐구의 초점이 되었다. Dwight Crandell과 Don Mullineau는 '과거는 미래의 열쇠이다'라는 관점으로 재해위험 매핑에 대한 지질학적 접근 방법을 개척했다. 세인트 헬렌즈산의 위험도 평가와 가까운 미래의 분출 예측에 대한 1978년 발간물, 그리고 1980년 대규모 분화로 화산위험 평가의 유용성이 입증되었고 화산 과학의 이 영역에서 거대한 성장이 시작되었다. 1980년대의 위험한 지역을 식별하기 위해 위험지역 이해 프로세스의 수치 모델을 개발하고 사용하기 시작했으며, 1990년대 후반부터 확산되었다. 수치모의 모델 산출물은 화산의 지질학적 지식에 의해 강조될 때 가장 유용하고 정확하다. 화산위험지도는 장기간의 무조건적인 화산 재해 위험을 묘사하는지, 어느 정도의 위험을 가진 모든 지역을 보여주는지, 화산이 불안정 또는 분화 위기 시에 개발되어 현재의 감시, 관찰 및 예보 정보를 고려한 지도로 크게 분류할 수 있다.