• Title/Summary/Keyword: hazardous substance

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Study on scheme for screening, quantification and interpretation of trace amounts of hazardous inorganic substances influencing hazard classification of a substance in REACH registration (REACH 물질 등록 시 분류에 영향을 주는 미량 유해 무기물질의 스크리닝·정량·해석을 위한 체계도 연구)

  • Kwon, Hyun-ah;Park, Kwang Seo;Son, Seung Hwan;Choe, Eun Kyung;Kim, Sanghun
    • Analytical Science and Technology
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    • v.32 no.6
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    • pp.233-242
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    • 2019
  • Substance identification is the first step of the REACH registration. It is essential in terms of Classification, Labelling and Packaging (CLP) regulation and because even trace amounts of impurities or additives can affect the classification. In this study, a scheme for the screening, quantification, and interpretation of trace amounts of hazardous inorganic substances is proposed to detect the presence of more than 0.1% hazardous inorganic substances that have been affecting the hazard classification. An exemplary list of hazardous inorganic substances was created from the substances of very high concern (SVHCs) in REACH. Among 201 SVHCs, there were 67 inorganic SVHCs containing at least one or ~2-3 heavy metals, such as As, Cd, Co, Cr, Pb, Sb, and Sn, in their molecular formula. The inorganic SVHCs are listed in excel format with a search function for these heavy metals so that the hazardous inorganic substances, including each heavy metal and the calculated ratio of its atomic weight to molecular weight of the hazardous inorganic substance containing it, can be searched. The case study was conducted to confirm the validity of the established scheme with zinc oxide (ZnO). In a substance that is made of ZnO, Pb was screened by XRF analysis and measured to be 0.04% (w/w) by ICP-OES analysis. After referring to the list, the presence of Pb was interpreted just as an impurity, but not as an impurity relevant for the classification. Future studies are needed to expand on this exemplary list of hazardous inorganic substances using proper regulatory data sources.

Development and Application of DNA Analysis Method for Identificaion of Main Ingredients in Starch (전분의 주원료 판별을 위한 유전자 분석법 개발 및 적용)

  • Park, Yong-Chjun;Kim, Mi-Ra;Kim, Yong-Sang;Lee, Ho-Yeon;Kim, Kyu-Heon;Lee, Jae-Hwang;Kim, Jae-I;Lee, Sang-Jae;Lee, Hwa-Jung
    • Journal of Food Hygiene and Safety
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    • v.28 no.2
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    • pp.181-187
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    • 2013
  • Identification of main ingredients in starches has been investigated using physicochemical analysis method mainly. However, physicochemical properties such as particle size have limitations in determining the differences among mixed starches. Therefore, we developed a molecular biological method to identify materials used in starch, as a sample, 11 kinds of starches including sweet potato starch, potato starch, corn starch, and tapioca starch. DNeasy plant mini kit, magnetic DNA purification system, and CTAB methods were used to extract DNA from samples. After gene extraction, whole genome amplification (WGA) was performed to amplify the extracted DNA. Species-specific primers were used as followings: ib-286-F/ib-286-R (105 bp), Pss 01n-5'/Pss 01n-3' (216 bp), SS11b 3-5'/SS11b 3-3' (114 bp), and SSRY26-F/SSRY26-R (121 bp) gene for sweet potato, potato, corn, and tapioca, respectively. In this study, we could confirm the main ingredients using WGA and PCR method.

Survey on Sodium and Potassium Content of School Meals as well as Sodium and Potassium Intake by Students in the Daejeon and Chungcheong Area (대전.충청 지역 초.중학교 급식의 나트륨, 칼륨 함량 및 섭취량 조사)

  • Lee, Eun-Mi;Park, You-Gyoung;Jung, Woo-Young;Kim, Mi-Ra;Seo, Eun-Chae;Jung, Rae-Seok;Na, Mi-Ae;Lee, Jin-Ha;Heo, Ok-Soon
    • Journal of the East Asian Society of Dietary Life
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    • v.20 no.6
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    • pp.853-862
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    • 2010
  • This study was conducted as a nationwide project in order to obtain data on the content and intake of sodium in school meals. For this purpose, we selected two elementary and two middle schools in Daejeon as well as four elementary schools in the Chungcheong area. We measured the sodium and potassium contents of 842 dishes as well as their intake levels over 154 days. Sodium content was analyzed using an AAS (Atomic Absorption Spectrometer). The average meal intakes of second and fifth grade elementary school students were 244 g/meal and 304 g/meal, respectively. The meal intake of middle school students was 401 g/meal. Boys tended to eat slightly more than did girls, and students tended to eat more in the spring than in the summer. The average sodium intake per meal was 642 mg (570 mg by elementary school students, 1068 mg by middle school students), which was 32.1% of the UL (Tolerable Upper Intake Level, 2,000 mg per day) according to the KDRIs (Dietary Reference Intakes for Koreans). The sodium intake per meal was not significantly differ between boys and girls or between spring and summer (p>0.05). This study provides fundamental data that can be used to establishment a nutrition policy concerning the adequate content of sodium in school meals.

Development of Analytical Method and Monitoring of Veterinary Drug Residues in Korean Animal Products

  • Song, Jae-Sang;Park, Su-Jeong;Choi, Jung-Yun;Kim, Jin-Sook;Kang, Myung-Hee;Choi, Bo-Kyung;Hur, Sun Jin
    • Food Science of Animal Resources
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    • v.36 no.3
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    • pp.319-325
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    • 2016
  • This study was conducted to determine the residual amount of veterinary drugs such as meloxicam, flunixin, and tulathromycin in animal products (beef, pork, horsemeat, and milk). Veterinary drugs have been widely used in the rearing of livestock to prevent and treat diseases. A total of 152 samples were purchased from markets located in major Korean cities (Seoul, Busan, Incheon, Daegu, Daejeon, Gwangju, Ulsan and Jeju), including Jeju. Veterinary drugs were analyzed by liquid chromatography-tandem mass spectrometry according to the Korean Food Standards Code. The resulting data, which are located within 70-120% of recovery range and less than 20% of relative standard deviations, are in compliance with the criteria of CODEX. A total of five veterinary drugs were detected in 152 samples, giving a detection rate of approximately 3.3%; and no food source violated the guideline values. Our result indicated that most of the veterinary drug residues in animal products were below the maximum residue limits specified in Korea.