• Journal of Environmental Health Sciences
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• v.46 no.4
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• pp.398-409
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• 2020

Objectives: This study aimed to evaluate environmental exposure to tobacco-specific nitrosamines (TSNAs) by conducting an analysis of the concentration of TSNAs in deposited dust collected from a fertilizer plant and the surrounding village, a simulation of high-temperature drying of tobacco waste, and CALPUFF modeling. Methods: The raw materials of the products, deposited dust (inside and outside the plant and residential area), soil, and wastewater were sampled and the TSNA concentrations were analyzed by LC-MS/MS. As the plant was closed down before the investigation, simulation tests were conducted to confirm the substances discharged during high-temperature (300℃) drying of tobacco waste. CALPUFF modeling was performed to identify the area of influence due to exposure to TSNAs. Results: TSNAs were detected in organic fertilizers estimated to contain tobacco waste, deposited dust, and soil collected from inside and outside the plant. N'-nitrosonornicotine (NNN), 4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanone (NNK), and N'-nitrosoanatabine (NAT) components were detected in five of 15 deposited dust samples collected from the residential area around the plant, while TSNAs were not detected in the five sampling points in the control area. Also, the simulation test for the high temperature drying of tobacco waste found emissions of TSNAs. The CALPUFF modeling results showed that the survey area was likely to be included in the area of influence of TSNA emissions from the plant. Conclusions: It is estimated that harmful tobacco ingredients such as TSNAs were dispersed in nearby areas due to the illegal use of tobacco waste as a raw material to produce organic fertilizers at the plant. These findings assume that the residents have been exposed to TSNAs and suggest that the need for the establishment of measures to manage environmental health.

• Journal of Nutrition and Health
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• v.37 no.9
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• pp.786-793
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• 2004

Women with menopause or rats with ovariectomy is associated with increased body weight, body fat and insulin resistance, which are components of metabolic syndrome. Increased prevalence of metabolic syndrome after menopause might be associated with mitochondrial dysfunction, since mitochondrial oxidative and phosphorylation activity is strongly correlated with insulin sensitivity. Although estradiol replacement prevents the metabolic syndrome, harmful effect of estradiol hampers the casual usage to prevent the metabolic syndrome. It has been reported that genistein has a mild estrogenic activity, decreases fat mass in mice and has an antidiabetic role in diabetic rats. Although insulin resistance is closely related to mitochondrial functions, there has not been yet any study in regard to the effect of dietary genistein on mitochondrial function in the insulin resistant female subjects induced by ovariectomy or similar situation. The present study investigated whether the supplementation of genistein in the high fat diet affected the mitochondrial function of high fat fed ovariectomized rats. Female Sprague Dawley rats (8 weeks old) were assigned to the following groups: sham-operated+ high fat diet (S, n=6); sham-operated + high fat diet with 0.1% genistein (S + G, n=7); ovariectomized + high fat diet (OVX, n=8); ovariectomized + high fat diet with 0.1% genistein (OVX+ G, n=8). Ovariectomy significantly increased body weight compared with S group. Genistein consumption in ovariectomized (OVX + G) rats decreased body weight gain compared with OVX rats. Liver weights were increased by ovariectomy. The hepatic mitochondrial protein density expressed as mg per g liver was lower in the OVX group than in the S group. However, OVX + G group showed the increased mitochondrial protein density similar to the level of S group. When mRNA levels of genes related to mitochondria such as peroxisome proliferator-activated receptor ${\gamma}$ coactivator 1 (PGC-1) and cytochrome c oxidase subunit III (COX III) were measured, there were decreases in the mRNA levels of PGC-1 and COX III in S + G, OVX and OVX + G group. The activity of cytochrome c oxidase was not different between groups. We could observe the decrease in succinate dehydrogenase (SDH) activity per g liver in OVX rats. Genistein supplement increased SDH activity. In conclusion, genistein supplementation to the OVX rats enhanced mitochondrial function by increasing mitochondrial protein density and SDH activity. The improvement in mitochondrial function by genistein can contribute to the improvement in metabolic syndrome.

• Journal of Environmental Impact Assessment
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• v.23 no.2
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• pp.75-87
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• 2014

In order to analyze environmental impact of livestock manure and organic fertilizers, this study investigated livestock-breeding and pollution loads, the status of individual and public livestock manure treatment facilities, and the status of production, supply and components of compost and liquid fertilizers in the Nonsan area. Also, on a trial basis, this study investigated the life cycle of the environmental impact of livestock manure and its organic fertilizers on stream, groundwater, and agricultural soil. The results are as follows. Firstly, were detected the range of $0.13{\sim}1.32{\mu}g/L$ of As, $0.004{\sim}0.467{\mu}g/L$ of Cd and $0.5{\sim}9.2{\mu}g/L$ of Pb as a harmful substances which show lower concentrations than person preservation criteria of water qualities and aquatic ecosystem. However, it is not clear that heavy metals affect environment such as stream, groundwater and agricultural soil. Secondly, this influence could change according to investigation time and treatment efficiency. As were detected large amounts of persistent organic pollutants(e.g. $14.24{\sim}38.47{\mu}g/L$ of acetylsalicylic acid, $1.17{\sim}2.96{\mu}g/L$ of sulfamethazine, and $2.25{\sim}174.09{\mu}g/L$ of sulfathiazole) in effluent from livestock farms and small amounts of sulfathiazole($ND{\sim}1.63{\mu}g/L$) in the stream, it is necessary to monitor POPs at individual and public livestock manure treatment facilities. However, significant environmental impact did not appear at groundwater and agricultural soil in the test area supplied with liquid fertilizers. These results could be applied to investigate the environmental impact of livestock manure through a comprehensive livestock manure management information system.

• Korean Journal of Poultry Science
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• v.28 no.3
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• pp.245-257
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• 2001

Localization of livestock facilities leads to concentration of livestock wastes and subsequent leakage of pollutants into the environment, resulting in public concern about their effects. Nitrogen (N) and phosphorus (P) are the most harmful components of animal manure, but odor from the manure itself and the livestock facilities is also a problem. Improving the nutrient efficiency of the livestock helps to decrease excretion of these environmental contaminants. Pigs and chickens are the main experimental models used in studies to improve nutrient efficiency. Addition of feed supplements and modifying feeding systems to improve nutrient efficiency can result in significant decrease in the N, P, odor and dry matter (DM) weight of manure. Examples of these methods include the following. 1) Addition of synthetic amino acids and reducing protein contents resulted N reductions of 10∼27% in broilers, 18∼35% in chicks and layers, 19∼62% in pigs, and a 9∼43% reduction in odor in pigs. 2) Enzyme supplementation resulted in a 12∼15% reduction in DM weight in broiler manure. 3) Phvtase supplementation resulted in P reductions of 25∼35% in chickens and 20∼60% in pigs. 4) Use of growth promoting substances resulted in a 5∼30% reduction in N and a 53∼56% reduction in odor of pigs. 5) Formulating diets closer to requirements (diet modification) reduced N and P by 10∼15% each in chickens and pigs, and odor by 28∼ 79% in pigs. 6) Phase feeding reduced N and P excretion by chicken and pigs from 10∼33% and 10∼13% each, as well as odor in growing and finishing pigs by 49∼79%. 7) Use of highly digestible raw materials in feed reduced N and P excretion by 5% in chickens and pigs.

• Journal of Nutrition and Health
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• v.10 no.2
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• pp.18-26
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• 1977

Among animals, the rabbit is known to be affected most sensitively by dietary changes and to be most susceptible to atherosclerosis. The exact reason is still unknown as to whether the primary cause is intrinsic (tissue itself) or extrinsic such as a blood factor which could be influenced by various dietary means. It is of utmost importance to check the nutritional quality of rabbit meat before it is accepted and adapted as a daily food item. To evaluate nutritional quality of rabbit meat, studies on various aspects of lipid components were carried out in comparison with other animal meats such as beef, pork and chicken also included in the study was the question whether the cooking and storage conditions influence the composition of fatty acids and cholesterol level. Some results and findings are listed below: 1. The content of linoleic acid (18 : 2), one of the essential fatty acids, was much higher in rabbit meat compared to the other meats. The Percentages of this Polyunsaturated fatty acids, was much higher in rabbit meat compared to the other meats. The percentages of this polyunsaturated fatty acid in terms of total fatty acids were $37.3{\pm}3.7$, 5.9, 14.5, and 21.9% for rabbit, beef, pork, and chicken respectively. The degree of unsaturation was high not only in meat but also in liver and adipose tissue of rabbit. The values of iodine number, the indication of degree of unsaturation, were known to be $102{\sim}107$, $32{\sim}47$, $46{\sim}67$, and $55{\sim}77$ for rabbit, beef, pork, and chicken respectively. Such a high proportion of this polyunsaturated fatty acid contained in rabbit meat could be harmful due to their Peroxidation effect. 2. A small amount of lower (short chain) fatty acids was isolated from rabbit tussues, which were not observed in other animal's tissues. The significance of this small amount of short chain fatty acids contained in rabbit meat remained an open question. 3. The concentration of total cholesterol in rabbit meat was similar to that of otherr but the content of esterified cholesterol was higher in rabbit meat. This was probably due to the perference of cholesterol to esterify with unsaturated fatty acids. By roasting the percentage of Polyunsaturated fatty acids was decreased while saturated palmitic acid was proportionally increased. 4 The composition of fatty acids were affected more by dry heat than moist heat. More research should be pursued to improve methods of preservation and storage to prevent possible peroxidation and rancidity problems of rabbit meat. In the meantime, the public should be informed to eat fresh rabbit meat and not to store it for a long period of time. This study was supported by the Ministry of Science and Technology in Korea.

• Journal of the Korean Recycled Construction Resources Institute
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• v.5 no.2
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• pp.105-115
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• 2010

In this study, as one of solutions associated with the shortage of treatment area of industrial waste and the containment of its harmful components, the bottom ash which is known to be by-products of thermoelectric power plant was selected and its applicability for aggregate of concrete mixture was measured. Hardness test, sieve analysis, water-absorption test and SEM analysis were carried out to investigate the possibility of using bottom ash as a replacement of coarse and fine aggregate. Chemical analyses such as ignition loss test and X-ray incidence were carried out also. In addition, values for slump, strength, permeability, freeze and thaw, and carbonation were evaluated in terms of effects of replacement ratio of bottom ash. As the results, it was found that, though bottom ash is in short supply of fine particles and is in lack of cohesion, these problems can be solved by partially mixing with natural aggregates or improving in a process of production. In addition, bottom ash has not only advantage of durability but also acquirement of general compressive strengths in case that a certain proportion of natural aggregate is applied to mixture, in spite that unit water or chemical admixture should be increased to acquire good workability due to plenty of porosity.

• Journal of the Korean Applied Science and Technology
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• v.37 no.4
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• pp.906-914
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• 2020

To investigate the usefulness of natural plants, physicochemical characteristics, functional components and physiological activities of dodder(Cuscuta australis R.Brown) were experimented. The extraction of dodder was carried out at 60℃ in shaking bath with 10 times of distilled water for three hours. Harmful metals such as lead, cadmium and arsenic were not detected, but the content of mercury from dodder was 0.0004ppm in acceptable standards. The extraction yield was 23.45%, total content of phenolics equivalent to gallic acid was 699.8 mg/100g and total content of flavonoid equivalent to naringin was 373.8 mg/100g. 28 kinds of free amino acids were detected with the contents of 252mg/100g in the dodder extract, and the contents of anserine and sarcosine were analysed highest in all amino acids. From the comparison of physiological activities of dodder extract with those of ascorbic acid, total reducing power, electron donating ability based on DPPH radical scavenging and ferric reducing antioxidant power was equivalent to 88%, 56% and 40%, respectively, of ascorbic acid. The nitrite scavenging activity of dodder extract was 78% of ascorbic acid on pH 1.5, but the antioxidant index of dodder on perilla oil was about 4 times greater than that of ascorbic acid.

• Journal of Navigation and Port Research
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• v.41 no.3
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• pp.79-86
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• 2017

Ballast water filled into and discharged from the ballast tank of a ship has a negative impact on local marine environment due to various aquatic organisms contained therein. The IMO developed and adopted "The International Convention for the Control and Management of Ships Ballast Water and Sediments, 2004" with the purpose of protecting the marine environment from transfer of harmful aquatic organisms in ballast water carried by ships. The IMO BWM Convention was approved in September 2016 and ships must be equipped with ballast water management system after September 2017. Ships' ballast water treatment methods are divided into using active substances as electrolytic type, ozone type, chemical dosing type and using physical treatment type as filter type, ultraviolet type. It is also used with a combination of two methods. Electrolysis is superior in terms of cost and efficiency. In this study, basic principles, components, and land base test contents of electrolysis ballast water treatment system, a direct electrolyzed ballast water treatment system, were examined. Land base test was conducted with 300m3/h capacity device at the KIOST Geoje plant where the government test facility was installed. This test validated that the system meets IMO standards.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.5
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• pp.16-21
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• 2017

The aim of this study was to utilize ferronickel slag produced in the manufacture of stainless steel as a flowable backfill material for underground use using crushed fine powder. Experimental combinations were made using two components: Case A (sand) and Case B (soil). The optimal mixing ratio of Case A was sand (58.4%), ferronickel slag fine powder (21.6%), cement (1.8%), and water (18.2%). In the case of B, the optimal mixing ratio was determined to be soil (53.0%), ferronickel slag fine powder (20.0%), cement (1.7%), and water (25.3%). The uniaxial compressive strength of case A, which is a mixture of ordinary sand and ferronickel slag powder, was relatively larger than that of case B using soil. In addition, the strength of the specimen increased with increasing curing time. The uniaxial compressive strength tended to increase with increasing curing time. In addition, the unconfined compression strength of the fluid backfill material using common sand as the main material was relatively larger than that of the mixed material using soil as the main material. In case A, the uniaxial compressive strength ranged from 0.17-0.33 MPa, 0.21-0.39 MPa, and 0.19-0.40 MPa, respectively, at curing times of 7, 14, and 28 days. From the experimental results, it was concluded that the ratio of FNS powder and cement mixture was the most appropriate for Case A3. Case B, which used soil as the main material, showed a similar tendency to Case A. As a result of the dissolution test for evaluating the environmental harm of the FNS fine powder, there was no dissolution of substances harmful to the environment.

• Applied Biological Chemistry
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• v.22 no.1
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• pp.58-63
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• 1979

The solvent extracting of the tobacco has been carried out in order to find out any effects for the removal and/or reduction of nicotine from tobacco without affecting the tobacco flavor. We have now completed the physico-chemical characterization of the solvent untreated/treated tobaccos and 2) the contents of the tar and nicotine in the smoke. The results obtained ate like followings; 1. 3% alcohol extraction reduced the total nitrogen content for the Bright by 36.4%. However, it could not reduce the sugar content. 2. Nicotine content in tobacco leaves was inversely proportional to the dipping time Essentially same results were obtained in anacidic solution and even in a solution containing both alkali and acid. 3. Derivative thermogravimetric(DTG) curves indicated test extraction was effective by removing tobacco leaf components which could decompose or volatilize between the temperature of $150^{\circ}C\;and\;350^{\circ}C$. 4. 3% alcohol extracted leaf have the substantial improvements as following; (1) bulk filling power of 10% and 24% for Burley and Bright tobacco, respectively, (2) combustibility shortening of about 3 minute and 2 minute for Burley and Bright tobaccos, respectively, (3) reduction ratio(%) of nicotine was found to be shout 61.5% and 54.5% for Burley and Bright tobacco, respectively, (4) reduction ratio (%) of tar was obtained to he about 25% and 15% for Burley and Bright tobacco, respectively.