• Title/Summary/Keyword: harmful components

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Antibacterial Activity of Pinus densiflora Leaf-Derived Components Toward Human Intestinal Bacteria

  • Hwang, Young-Hee;Lee, Hoi-Seon
    • Journal of Microbiology and Biotechnology
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    • v.12 no.4
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    • pp.610-616
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    • 2002
  • The growth-inhibiting effects of Pinus densiflpora leaf-derived materials on nine human intestinal bacteria were investigated using the impregnated paper disk method, and their activities were compared with those of 13 commercially available terpenes. The biologically active constituent of the extract of P densiflora leaf was characterized as the monoterpene (1R)-(+)-$\alpha$-pinene by various spectroscopic analyses. Responses varied according to bacterial strain, chemicals, and dose. At 10 mg/disk, limonene and (1R)-(+)-$\alpha$-pinene strongly inhibited the growth of Clostridium perfringens, Staphylococcus aureus, and Escherichia coli, without adverse effects on the growth of five lactic acid-bacteria (Bifidobacterium adolescentis, B. bifidum, B. longum, Lactobacillus acidophilus, and L. casei). Little or no inhibition against seven bacteria was observed with anethole, borneol, camphor, caryophyllene, 1,8-cineole, estragole, linalool, and $\alpha$-terpineol. Structure-activity relationship revealed that (1R)-(+)-$\alpha$-pinene had more growth-inhibiting activity against C. perfringens than (1R)-(+)-$\beta$-, (1S-(-)-$\alpha$-, and (1S-(-)-$\beta$-pinenes. Furthermore, the growth-inhibition against L. casei was much more pronounced in (1R)-(+)-$\beta$- and (In-(-)-$\beta$-pinenes than (1R)-(+)-$\alpha$- and (1S)-(-)-$\alpha$-pinenes. These results indicate that the (+)-$\alpha$ form seems to be required against C. perfringens and $\beta$ form against L. casei for growth-inhibiting activity. Morphologically, most strains of C. perfringens were damaged and disappeared at 5 and 2 mg/disk of (1R)-(+)-$\alpha$-pinene. Morphological study revealed that (1R)-(+)-$\alpha$-pinene had more growth-inhibiting activity against C. perfringens than (1R)-(+)-$\beta$-, (1S)-(-)-$\alpha$-, and (1S)-(-)-$\beta$-pinenes. As naturally occurring growth-inhibiting agents, the Pinus leaf-derived materials described above could be useful preventive agents against diseases caused by harmful intestinal bacteria such as clostridia.

Consumer's Behaviors on the Purchase and the Laundering of Baby's Clothing (유아복의 구매와 세탁에 관한 소비자 행동)

  • Kweon, Soo-Ae;Han, Mi-Ran;Lee, Jeong-Sook
    • Journal of the Korean Society of Fashion and Beauty
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    • v.4 no.4 s.10
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    • pp.33-41
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    • 2006
  • The purpose of this study was to investigate consumer's behaviors on the purchase and the laundering of baby's clothing according to washing machine types using by consumers. The subjects were 255 consumers with babies(0-2 years) in Korea. The data were collected using a self-administered questionnaire and analyzed using Chi-square test and multiple response analysis, and SPSS 12.0 statistics package was used. Consumers were separated into two groups according to washing machine types with general pulsator type and drum-type. Consumer's behaviors between general pulsator type group and drum-type group of washing machines were also examined. The Results of this study were as follows: 1. The purchase rate of baby's clothing was high compare to that of general clothing of family. The consumers with babies had priority on textile materials(cotton 100%) as baby's clothing. As for the consumer's behaviors between the purchase of baby's clothing and the consumer's characteristics, they showed a significant differences according to the consumer's characteristics like education level and washing machine types using by consumers. 2. The removal of soils including various foods was very important on the laundering of baby's clothing. Especially the rinsing of detergents was important on the laundering. Because they considered toxicity of detergents was high and harmful to the baby, and detergent's components such as surfactants, builders, and another additives could not removed completely with normal laundry courses by washing machines. 3. There were significant differences between general pulsator type group and drum-type group of washing machines on the purchase and the laundering of baby's clothing.

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Chemical Properties of Indoor Individual Particles Collected at the Daily Behavior Spaces of a Factory Worker

  • Ma, Chang-Jin;Kang, Gong-Unn;Sakai, Takuro
    • Asian Journal of Atmospheric Environment
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    • v.11 no.2
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    • pp.122-130
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    • 2017
  • The main purpose of the study was to clarify the properties of individual particles collected at each behavior space of a factory worker. The samplings of size-segregated ($PM_{2.1-1.1}$ and $PM_{4.7-3.3}$) indoor particles were conducted at three different behavior spaces of a factory worker who is engaged in an auto parts manufacturing plant (i.e., his home, his work place in factory, and his favorite restaurant). Elemental specification (i.e., relative elemental content and distribution in and/or on individual particles) was performed by a micro-PIXE system. Every element detected from the coarse particulate matters of home was classified into three groups, i.e., a group of high net-counts (Na, Al, and Si), a group of intermediate net-counts (Mg, S, Cl, K, and Ca), and a group of minor trace elements (P, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, and Pb). The results of EF for $PM_{4.7-3.3}$ in home indicated that several heavy metals were generated from the sources within the house itself. An exceptional feature shown in the individual particles in workplace is that Cr, Mn, and Co were clearly detected in both fine and coarse particles. Cluster analysis suggested that the individual coarse particles ($PM_{4.7-3.3}$) collected at the indoor of factory were chemically heterogeneous and they modified with sea-salt, mineral, and artificially derived elements. The principal components in individual coarse particles collected at restaurant were sea-salt and mineral without mixing with harmful trace elements like chromium and manganese. Compared to the indoor fine particles of home and restaurant, many elements, especially, Cl, Na, Cr, Mn, Pb, and Zn showed overwhelmingly high net-counts in those of factory.

Foam Separation in Recirculating Aquaculture System (순환여과식 양어장의 포말분리)

  • SUH Kuen-Hack;LEE Min-Gyu
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.30 no.2
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    • pp.239-243
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    • 1997
  • A continuous foam separator has been used to remove TSS, $NH_3\;and\;NO_2^-$ from the recirculating water in aquaculture. Experimental runs were carried out to determine the foam separation variables, such as, hydraulic retention time, superficial air velocity and foam .height. The removal efficiency of TSS, $NH_3\;and\;NO_2^-$ was increased with hydraulic retention time and superficial air velocity, and removal efficiency of $NH_3$ was increased steadily with foam height. As DO concentration was increased with superficial air velocity and foam height, foam separator is also used for oxygen addition. It was concluded that foam separator might offer better perspective for removal of harmful components in fish culture water.

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Modeling and Simulation of O2/CH4 Gas Supply System of Afterburner for Fuel-rich Gas of Gas Generator (가스발생기의 연료과잉가스 후연소용 O2/CH4 가스 공급시스템 설계)

  • Wang, Seungwon;Lee, Kwangjin;Chung, Yonggahp;Han, Yeoungmin
    • Journal of the Korean Society of Propulsion Engineers
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    • v.18 no.2
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    • pp.86-92
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    • 2014
  • Combustion Chamber Test Facility (CCTF) to be constructed in Naro Space Center for re-burning the fuel-rich gas of gas generator have afterburner system. The afterburner system is supplied the Oxygon ($O_2$) gas and Methane ($CH_4$) gas to reduced the harmful exhaust gas. The detailed design for the planned CCTF afterburner system is simulated and analysed by AMESim program through the all of gas supply system components. Afterburner system is performed to verify the pipe size, orifice diameter, and gas supply conditions according to the total gas consumption from analysis of gas supply system.

A Study on the Analysis of $CO_2$ Concentration Variation According to the Indoor Space Condition Changes (다양한 실내 환경에서의 $CO_2$ 농도 변화 분석 연구)

  • Ahn, Gwang-Hoon;Kwon, Jong-Won;Kim, Gyu-Sik;Kim, Hie-Sik
    • Proceedings of the IEEK Conference
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    • 2009.05a
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    • pp.347-349
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    • 2009
  • Air quality of indoor space environment is affected by various pollutants like as particles and chemical stuffs. The indoor air pollution affects directly the human respiration organs to cause consequently unpleasant mental status. The $CO_2$ concentration level is one of the harmful components of air pollutants. Major factor to increase the $CO_2$ concentration level is the people's breath amount in indoor. The car exhaust gas diffused from the around road also has strong affect on $CO_2$ concentration. There are some other reasons to affect the $CO_2$ concentration change, such as, real-time change of the population movement, closeness to the indoor air flow inlet window and changes in road car traffic amount. A remote monitoring system to measure environmental indoor air pollution concerning on the $CO_2$ concentration was studied and installed realized set-up model. Zigbee network configuration was applied for this system and the $CO_2$ concentration data were collected through USN network. A software program was developed to assure systematic analysis and to display real-time data on web pages. For the experimental test various condition was set up, like as, window opening, stopping air condition operation and adjusting fan heater work, etc. The analysis result showed the relation of various environmental conditions to $CO_2$ concentration changes. The causes to increase $CO_2$ concentration were experimentally defined as windows closing, the stopping air condition system, fan heater operation. To keep the $CO_2$ concentration under the legally required ppm level in public access indoor space, the developed remote measurement system will be usefully applied.

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Expression and regulation of avian beta-defensin 8 protein in immune tissues and cell lines of chickens

  • Rengaraj, Deivendran;Truong, Anh Duc;Lillehoj, Hyun S.;Han, Jae Yong;Hong, Yeong Ho
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.9
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    • pp.1516-1524
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    • 2018
  • Objective: Defensins are a large family of antimicrobial peptides and components of the innate immune system that invoke an immediate immune response against harmful pathogens. Defensins are classified into alpha-, beta-, and theta-defensins. Avian species only possess beta-defensins (AvBDs), and approximately 14 AvBDs (AvBD1-AvBD14) have been identified in chickens to date. Although substantial information is available on the conservation and phylogenetics, limited information is available on the expression and regulation of AvBD8 in chicken immune tissues and cells. Methods: We examined AvBD8 protein expression in immune tissues of White Leghorn chickens (WL) by immunohistochemistry and quantitative reverse transcription-polymerase chain reaction (RT-qPCR). In addition, we examined AvBD8 expression in chicken T-, B-, macrophage-, and fibroblast-cell lines and its regulation in these cells after lipopolysaccharide (LPS) treatment by immunocytochemistry and RT-qPCR. Results: Our results showed that chicken AvBD8 protein was strongly expressed in the WL intestine and in macrophages. AvBD8 gene expression was highly upregulated in macrophages treated with different LPS concentrations compared with that in T- and B-cell lines in a time-independent manner. Moreover, chicken AvBD8 strongly interacted with other AvBDs and with other antimicrobial peptides as determined by bioinformatics. Conclusion: Our study provides the expression and regulation of chicken AvBD8 protein in immune tissues and cells, which play crucial role in the innate immunity.

Effect of Genistein and Soy Protein on Lipids Metabolism in Ovariectomized Rats (난소절제 랫드에서 제니스테인과 콩단백질이 지질 대사에 미치는 영향)

  • Lee Young Min;Jung Myeong Ho;Lee Yeon Sook;Song Jihyun
    • Journal of Nutrition and Health
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    • v.38 no.4
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    • pp.267-278
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    • 2005
  • Postmenopausal women or ovariectomized rats are associated with increased cholesterol levels, which are risk factors of metabolic syndrome and cardiovascular diseases. Increased prevalence of metabolic syndrome after menopause might be associated with estradiol deficiency. Harmful effect of estradiol hampers the casual usage of hormone to prevent the metabolic syndrome. Soy protein has been reported to show several beneficial effects on health, however it is unclear which components of soy protein is responsible for anti-obesity and hypocholesterolemic effects. Soy isoflavones, gem-stein and daizein, are suggested to have anti-obesity and hypocholesterolemic effects but with inconsistency. The present study investigated the effect of supplementation of genistein (experiment I) and soy protein containing isoflavones (experiment II) to high fat diet on body weight gain, food intake, liver and fat tissue weight and the lipid levels in ovariectomized rats. Plasma and hepatic lipid contents and the mRNA levels of genes encoding lipid metabolism related proteins, such as CPT1 and HMGR were measured. Ovariectomy increased body weight, fat tissue weight and plasma and hepatic lipid levels which increase the risk of metabolic syndrome. Soy protein could improve plasma and hepatic lipids levels. Soy protein also increased hepatic CPT1 and HMGR mRNA levels. Plasma and hepatic lipids levels could not be decreased by dietary genistein alone. In contrast, lipids levels could be decreased by isoflavone-fortified soy protein, suggesting that the ingestion of soy protein enriched with isoflavone gives more benefit for protecting postmenopausal women from metabolic syndrome.

Long-Term Results of Microsurgical Selective Tibial Neurotomy for Spastic Foot : Comparison of Adult and Child

  • Kim, Jong-Hoon;Lee, Jae-Il;Kim, Min-Su;Kim, Seong-Ho
    • Journal of Korean Neurosurgical Society
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    • v.47 no.4
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    • pp.247-251
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    • 2010
  • Objective : Selective neurotomy is generally a safe, effective, and long-lasting treatment for patients with spastic equinovarus foot deformity. We retrospectively analyzed the results of microsurgical selective tibial neurotomy (STN) for spastic feet in adults and children. Methods : A neurosurgeon selected 32 patients with 45 spastic feet (adults : 13, children : 32) to undergo microsurgical STN between October 1998 and September 2007. A physician of rehabilitation assessed spasticity pre- and postoperatively, that was based on the Ashworth scale, ankle clonus, and the amplitude of ankle dorsiflexion. The mean postoperative follow-up period was 36.7 months in adults and 42.5 months in children. Results : Spastic components of the feet were corrected immediately after surgery in both the adult and child groups. The mean Ashworth's grade changed from $3.6{\pm}0.40$ to $1.6{\pm}0.70$ in adults and from $3.7{\pm}0.69$ to $1.4{\pm}0.49$ in children. Mean ankle clonus decreased markedly, from $1.6{\pm}0.79$ to $0.3{\pm}0.42$ in adults and from $1.7{\pm}0.65$ to $0.3{\pm}0.56$ in children. The mean amplitude of ankle dorsiflexion was improved, but eight (adults: 4, children: 4) contracted feet needed complementary orthopedic correction for acceptable results. Conclusion : STN can be effective in the long-term for improving lower limb function and reduction of equinovarus deformity. Our results demonstrate that STN might be an effective procedure for treating localized harmful spastic feet in adults and children.

Initial Sizing of General Aviation Aircraft Propelled by Electric Propulsion system (전기로 추진되는 일반 프로펠러 항공기의 초기 사이징)

  • Han, Hye-Sun;Shin, Kyo-Sic;Park, Hong-Ju;Hwang, Ho-Yon;Nam, Taewoo
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.41 no.5
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    • pp.391-403
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    • 2013
  • Propeller aircraft propelled by an electric propulsion system is gaining a renewed interest because of ever-increasing environmental concern on harmful emissions emitted from conventional jet engines and national energy security. Traditional aircraft sizing methods are not readily applicable to electric propulsion aircraft that utilize a variety of alternative energy sources and power generation systems. This study showcases an electric propulsion aircraft sizing exercise based on a generalized, power based sizing method. A general aviation aircraft is propelled by an electric propulsion system that comprises of a propeller, a high temperature super conducting motor, a Proton Exchange Membrance(PEM) fuel cell system fuelled with hydrogen, and power conditioning equipment. In order to assess the impact of technology progression, aircraft sizing was conducted for two different sets of technology assumptions for electric components, and the results were compared with conventional baseline aircraft.