• 제목/요약/키워드: harmful components

검색결과 149건 처리시간 0.032초

Antibacterial Activity of Pinus densiflora Leaf-Derived Components Toward Human Intestinal Bacteria

  • Hwang, Young-Hee;Lee, Hoi-Seon
    • Journal of Microbiology and Biotechnology
    • /
    • 제12권4호
    • /
    • pp.610-616
    • /
    • 2002
  • The growth-inhibiting effects of Pinus densiflpora leaf-derived materials on nine human intestinal bacteria were investigated using the impregnated paper disk method, and their activities were compared with those of 13 commercially available terpenes. The biologically active constituent of the extract of P densiflora leaf was characterized as the monoterpene (1R)-(+)-$\alpha$-pinene by various spectroscopic analyses. Responses varied according to bacterial strain, chemicals, and dose. At 10 mg/disk, limonene and (1R)-(+)-$\alpha$-pinene strongly inhibited the growth of Clostridium perfringens, Staphylococcus aureus, and Escherichia coli, without adverse effects on the growth of five lactic acid-bacteria (Bifidobacterium adolescentis, B. bifidum, B. longum, Lactobacillus acidophilus, and L. casei). Little or no inhibition against seven bacteria was observed with anethole, borneol, camphor, caryophyllene, 1,8-cineole, estragole, linalool, and $\alpha$-terpineol. Structure-activity relationship revealed that (1R)-(+)-$\alpha$-pinene had more growth-inhibiting activity against C. perfringens than (1R)-(+)-$\beta$-, (1S-(-)-$\alpha$-, and (1S-(-)-$\beta$-pinenes. Furthermore, the growth-inhibition against L. casei was much more pronounced in (1R)-(+)-$\beta$- and (In-(-)-$\beta$-pinenes than (1R)-(+)-$\alpha$- and (1S)-(-)-$\alpha$-pinenes. These results indicate that the (+)-$\alpha$ form seems to be required against C. perfringens and $\beta$ form against L. casei for growth-inhibiting activity. Morphologically, most strains of C. perfringens were damaged and disappeared at 5 and 2 mg/disk of (1R)-(+)-$\alpha$-pinene. Morphological study revealed that (1R)-(+)-$\alpha$-pinene had more growth-inhibiting activity against C. perfringens than (1R)-(+)-$\beta$-, (1S)-(-)-$\alpha$-, and (1S)-(-)-$\beta$-pinenes. As naturally occurring growth-inhibiting agents, the Pinus leaf-derived materials described above could be useful preventive agents against diseases caused by harmful intestinal bacteria such as clostridia.

유아복의 구매와 세탁에 관한 소비자 행동 (Consumer's Behaviors on the Purchase and the Laundering of Baby's Clothing)

  • 권수애;한미란;이정숙
    • 한국패션뷰티학회지
    • /
    • 제4권4호
    • /
    • pp.33-41
    • /
    • 2006
  • The purpose of this study was to investigate consumer's behaviors on the purchase and the laundering of baby's clothing according to washing machine types using by consumers. The subjects were 255 consumers with babies(0-2 years) in Korea. The data were collected using a self-administered questionnaire and analyzed using Chi-square test and multiple response analysis, and SPSS 12.0 statistics package was used. Consumers were separated into two groups according to washing machine types with general pulsator type and drum-type. Consumer's behaviors between general pulsator type group and drum-type group of washing machines were also examined. The Results of this study were as follows: 1. The purchase rate of baby's clothing was high compare to that of general clothing of family. The consumers with babies had priority on textile materials(cotton 100%) as baby's clothing. As for the consumer's behaviors between the purchase of baby's clothing and the consumer's characteristics, they showed a significant differences according to the consumer's characteristics like education level and washing machine types using by consumers. 2. The removal of soils including various foods was very important on the laundering of baby's clothing. Especially the rinsing of detergents was important on the laundering. Because they considered toxicity of detergents was high and harmful to the baby, and detergent's components such as surfactants, builders, and another additives could not removed completely with normal laundry courses by washing machines. 3. There were significant differences between general pulsator type group and drum-type group of washing machines on the purchase and the laundering of baby's clothing.

  • PDF

Chemical Properties of Indoor Individual Particles Collected at the Daily Behavior Spaces of a Factory Worker

  • Ma, Chang-Jin;Kang, Gong-Unn;Sakai, Takuro
    • Asian Journal of Atmospheric Environment
    • /
    • 제11권2호
    • /
    • pp.122-130
    • /
    • 2017
  • The main purpose of the study was to clarify the properties of individual particles collected at each behavior space of a factory worker. The samplings of size-segregated ($PM_{2.1-1.1}$ and $PM_{4.7-3.3}$) indoor particles were conducted at three different behavior spaces of a factory worker who is engaged in an auto parts manufacturing plant (i.e., his home, his work place in factory, and his favorite restaurant). Elemental specification (i.e., relative elemental content and distribution in and/or on individual particles) was performed by a micro-PIXE system. Every element detected from the coarse particulate matters of home was classified into three groups, i.e., a group of high net-counts (Na, Al, and Si), a group of intermediate net-counts (Mg, S, Cl, K, and Ca), and a group of minor trace elements (P, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, and Pb). The results of EF for $PM_{4.7-3.3}$ in home indicated that several heavy metals were generated from the sources within the house itself. An exceptional feature shown in the individual particles in workplace is that Cr, Mn, and Co were clearly detected in both fine and coarse particles. Cluster analysis suggested that the individual coarse particles ($PM_{4.7-3.3}$) collected at the indoor of factory were chemically heterogeneous and they modified with sea-salt, mineral, and artificially derived elements. The principal components in individual coarse particles collected at restaurant were sea-salt and mineral without mixing with harmful trace elements like chromium and manganese. Compared to the indoor fine particles of home and restaurant, many elements, especially, Cl, Na, Cr, Mn, Pb, and Zn showed overwhelmingly high net-counts in those of factory.

순환여과식 양어장의 포말분리 (Foam Separation in Recirculating Aquaculture System)

  • 서근학;이민규
    • 한국수산과학회지
    • /
    • 제30권2호
    • /
    • pp.239-243
    • /
    • 1997
  • 포말분리관에서 양어장 순환수를 일정하게 공급하여 분리 실험을 수행하며 체류 시간, 공탑 공기 유속, 포말층 높이 등의 영향에 따른 포말 분리관의 각 성분의 분리 특성을 연구한 결과 체류 시간 및 공탑 공기 유속이 증가할수록 TSS, TA및 $NO_2^-$ 성분의 제거율도 비례적으로 증가하였다. 그리고 포말층의 높이가 증가할수록 TA의 제거율은 월등히 증가한 반면에 $NO_2^-$, TSS의 제거율은 일정하게 유지되었다. 포말분리기의 공탑 공기 유속 및 포말층 높이가 증가할수록 순환수내의 용존산소도 증가하여 포말분리기는 양어장 순환수의 산소 공급 장치로도 활용되었다. 포말분리법은 어류 성장에 유해한 TSS, TA, $NO_2^-$를 단기간에 제거할 수 있고 어류 성장에 필요한 산소를 공급할 수 있는 매우 효과적인 방법으로 판단되었다.

  • PDF

가스발생기의 연료과잉가스 후연소용 O2/CH4 가스 공급시스템 설계 (Modeling and Simulation of O2/CH4 Gas Supply System of Afterburner for Fuel-rich Gas of Gas Generator)

  • 왕승원;이광진;정용갑;한영민
    • 한국추진공학회지
    • /
    • 제18권2호
    • /
    • pp.86-92
    • /
    • 2014
  • 나로우주센터에 구축되는 연소기 연소시험설비(CCTF)에는 한국형발사체(KSLV-II)에 적용된 터보펌프식 엔진의 가스발생기 시험시 생성되는 연료과잉가스를 연소시키기 위한 후연소시스템이 포함되어 있다. 후연소시스템은 $O_2$$CH_4$ 가스를 공급받아 연료과잉가스를 소모시킨다. 본 연구는 연소기 연소시험설비의 상세설계 자료를 바탕으로 후연소시스템의 가스공급시스템에 대해 AMESim 상용프로그램을 이용하여 해석하였다. 그 결과 상세설계에 적용된 레귤레이터, 공급배관, 오리피스크기 등으로 가스사용량을 예측하고, 상세설계의 타당성을 검증하였다.

다양한 실내 환경에서의 $CO_2$ 농도 변화 분석 연구 (A Study on the Analysis of $CO_2$ Concentration Variation According to the Indoor Space Condition Changes)

  • 안광훈;권종원;김규식;김희식
    • 대한전자공학회:학술대회논문집
    • /
    • 대한전자공학회 2009년도 정보 및 제어 심포지움 논문집
    • /
    • pp.347-349
    • /
    • 2009
  • Air quality of indoor space environment is affected by various pollutants like as particles and chemical stuffs. The indoor air pollution affects directly the human respiration organs to cause consequently unpleasant mental status. The $CO_2$ concentration level is one of the harmful components of air pollutants. Major factor to increase the $CO_2$ concentration level is the people's breath amount in indoor. The car exhaust gas diffused from the around road also has strong affect on $CO_2$ concentration. There are some other reasons to affect the $CO_2$ concentration change, such as, real-time change of the population movement, closeness to the indoor air flow inlet window and changes in road car traffic amount. A remote monitoring system to measure environmental indoor air pollution concerning on the $CO_2$ concentration was studied and installed realized set-up model. Zigbee network configuration was applied for this system and the $CO_2$ concentration data were collected through USN network. A software program was developed to assure systematic analysis and to display real-time data on web pages. For the experimental test various condition was set up, like as, window opening, stopping air condition operation and adjusting fan heater work, etc. The analysis result showed the relation of various environmental conditions to $CO_2$ concentration changes. The causes to increase $CO_2$ concentration were experimentally defined as windows closing, the stopping air condition system, fan heater operation. To keep the $CO_2$ concentration under the legally required ppm level in public access indoor space, the developed remote measurement system will be usefully applied.

  • PDF

Expression and regulation of avian beta-defensin 8 protein in immune tissues and cell lines of chickens

  • Rengaraj, Deivendran;Truong, Anh Duc;Lillehoj, Hyun S.;Han, Jae Yong;Hong, Yeong Ho
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제31권9호
    • /
    • pp.1516-1524
    • /
    • 2018
  • Objective: Defensins are a large family of antimicrobial peptides and components of the innate immune system that invoke an immediate immune response against harmful pathogens. Defensins are classified into alpha-, beta-, and theta-defensins. Avian species only possess beta-defensins (AvBDs), and approximately 14 AvBDs (AvBD1-AvBD14) have been identified in chickens to date. Although substantial information is available on the conservation and phylogenetics, limited information is available on the expression and regulation of AvBD8 in chicken immune tissues and cells. Methods: We examined AvBD8 protein expression in immune tissues of White Leghorn chickens (WL) by immunohistochemistry and quantitative reverse transcription-polymerase chain reaction (RT-qPCR). In addition, we examined AvBD8 expression in chicken T-, B-, macrophage-, and fibroblast-cell lines and its regulation in these cells after lipopolysaccharide (LPS) treatment by immunocytochemistry and RT-qPCR. Results: Our results showed that chicken AvBD8 protein was strongly expressed in the WL intestine and in macrophages. AvBD8 gene expression was highly upregulated in macrophages treated with different LPS concentrations compared with that in T- and B-cell lines in a time-independent manner. Moreover, chicken AvBD8 strongly interacted with other AvBDs and with other antimicrobial peptides as determined by bioinformatics. Conclusion: Our study provides the expression and regulation of chicken AvBD8 protein in immune tissues and cells, which play crucial role in the innate immunity.

난소절제 랫드에서 제니스테인과 콩단백질이 지질 대사에 미치는 영향 (Effect of Genistein and Soy Protein on Lipids Metabolism in Ovariectomized Rats)

  • 이영민;정명호;이연숙;송지현
    • Journal of Nutrition and Health
    • /
    • 제38권4호
    • /
    • pp.267-278
    • /
    • 2005
  • Postmenopausal women or ovariectomized rats are associated with increased cholesterol levels, which are risk factors of metabolic syndrome and cardiovascular diseases. Increased prevalence of metabolic syndrome after menopause might be associated with estradiol deficiency. Harmful effect of estradiol hampers the casual usage of hormone to prevent the metabolic syndrome. Soy protein has been reported to show several beneficial effects on health, however it is unclear which components of soy protein is responsible for anti-obesity and hypocholesterolemic effects. Soy isoflavones, gem-stein and daizein, are suggested to have anti-obesity and hypocholesterolemic effects but with inconsistency. The present study investigated the effect of supplementation of genistein (experiment I) and soy protein containing isoflavones (experiment II) to high fat diet on body weight gain, food intake, liver and fat tissue weight and the lipid levels in ovariectomized rats. Plasma and hepatic lipid contents and the mRNA levels of genes encoding lipid metabolism related proteins, such as CPT1 and HMGR were measured. Ovariectomy increased body weight, fat tissue weight and plasma and hepatic lipid levels which increase the risk of metabolic syndrome. Soy protein could improve plasma and hepatic lipids levels. Soy protein also increased hepatic CPT1 and HMGR mRNA levels. Plasma and hepatic lipids levels could not be decreased by dietary genistein alone. In contrast, lipids levels could be decreased by isoflavone-fortified soy protein, suggesting that the ingestion of soy protein enriched with isoflavone gives more benefit for protecting postmenopausal women from metabolic syndrome.

Long-Term Results of Microsurgical Selective Tibial Neurotomy for Spastic Foot : Comparison of Adult and Child

  • Kim, Jong-Hoon;Lee, Jae-Il;Kim, Min-Su;Kim, Seong-Ho
    • Journal of Korean Neurosurgical Society
    • /
    • 제47권4호
    • /
    • pp.247-251
    • /
    • 2010
  • Objective : Selective neurotomy is generally a safe, effective, and long-lasting treatment for patients with spastic equinovarus foot deformity. We retrospectively analyzed the results of microsurgical selective tibial neurotomy (STN) for spastic feet in adults and children. Methods : A neurosurgeon selected 32 patients with 45 spastic feet (adults : 13, children : 32) to undergo microsurgical STN between October 1998 and September 2007. A physician of rehabilitation assessed spasticity pre- and postoperatively, that was based on the Ashworth scale, ankle clonus, and the amplitude of ankle dorsiflexion. The mean postoperative follow-up period was 36.7 months in adults and 42.5 months in children. Results : Spastic components of the feet were corrected immediately after surgery in both the adult and child groups. The mean Ashworth's grade changed from $3.6{\pm}0.40$ to $1.6{\pm}0.70$ in adults and from $3.7{\pm}0.69$ to $1.4{\pm}0.49$ in children. Mean ankle clonus decreased markedly, from $1.6{\pm}0.79$ to $0.3{\pm}0.42$ in adults and from $1.7{\pm}0.65$ to $0.3{\pm}0.56$ in children. The mean amplitude of ankle dorsiflexion was improved, but eight (adults: 4, children: 4) contracted feet needed complementary orthopedic correction for acceptable results. Conclusion : STN can be effective in the long-term for improving lower limb function and reduction of equinovarus deformity. Our results demonstrate that STN might be an effective procedure for treating localized harmful spastic feet in adults and children.

전기로 추진되는 일반 프로펠러 항공기의 초기 사이징 (Initial Sizing of General Aviation Aircraft Propelled by Electric Propulsion system)

  • 한혜선;신교식;박홍주;황호연;남태우
    • 한국항공우주학회지
    • /
    • 제41권5호
    • /
    • pp.391-403
    • /
    • 2013
  • 전기 추진 프로펠러 항공기는 기존의 제트엔진으로부터 나오는 유해한 배기가스로 인한 환경적 우려와 국가 에너지 안보 차원에서 새로운 관심을 받고 있다. 그러나 전통적인 항공기 사이징 방법들은 여러 종류의 에너지원과 동력 시스템을 사용하는 전기 추진 항공기에 바로 적용될 수 없다. 본 연구에서는 일반화된 동력기반 사이징 기법에 기초한 전기 추진 항공기 사이징의 실제 예를 제시하였다. 여기서 일반 항공기는 프로펠러, 고온초전도모터, 수소가 연료로 사용되는 연료전지, 동력 조절 장치로 구성되는 전기 추진시스템에 의해 구동된다. 기술 향상의 영향을 평가하기 위해 전기 구성품들의 두 가지 다른 기술 구성을 가정하여 항공기 사이징을 수행하였고, 전형적인 형태의 기준 항공기와 사이징 결과를 비교하였다.