• Title/Summary/Keyword: haptotaxis

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GLOBAL SOLUTIONS TO CHEMOTAXIS-HAPTOTAXIS TUMOR INVASION SYSTEM WITH TISSUE RE-ESTABLISHMENT

  • Kang, Ensil;Lee, Jihoon
    • Journal of the Chungcheong Mathematical Society
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    • v.28 no.1
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    • pp.161-172
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    • 2015
  • In this paper, we consider the chemotaxis-haptotaxis model of tumor invasion with the proliferation and tissue re-establishment term in dimensions one and two. We show the global in time existence of a unique classical solution for the the model in two dimensional spatial domain without any restrictions on the coefficients.

A STUDY ON CANCER CELL INVASION WITH A THREE-DIMENSIONAL DYNAMIC MULTI-PHYSICS MODEL (3차원 동적 다중물리 모델 기반 암세포 증식과정 예측기술 개발)

  • Song, J.;Zhang, L.;Kim, D.
    • 한국전산유체공학회:학술대회논문집
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    • 2010.05a
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    • pp.556-561
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    • 2010
  • This paper proposes a three-dimensional haptotaxis model to simulate the migration of the population of cancer cells. The invasion of the cancer cells relates with the hapto- and the effect of the energy between cells and (ECM). The diffuse interface model is employed, which incorporates haptotaxis mechanism and interface energies. The semi-implicit Fourier spectral scheme is adopted for efficient complications. The simulation results reveal rich dynamics of cancer cells migration.

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