• 전자공학회논문지
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• 제51권1호
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• pp.97-103
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• 2014

본 논문에서는 1/8-rate 위상검출기를 이용한 클록-데이터 복원회로를 제안한다. 기존의 full-rate 또는 half-rate 위상검출기의 사용은 동일 데이터 속도에서 복원된 클록의 주파수가 상대적으로 높아야 하므로 샘플링회로와 VCO의 설계에 부담으로 작용한다. 본 논문에서는 복원된 클록의 주파수를 낮추기 위해 1/8-rate 클록을 사용할 수 있는 위상검출기를 구성하고 Linear equalizer를 위상검출기 입력에 사용하여 복원된 클록의 지터를 감소시켰다. 테스트 칩은 0.13-${\mu}m$ CMOS 공정으로 제작되었고 입력은 3-Gb/s PRBS 데이터 패턴, 동작전압은 1.2-V에서 측정되었다.

• JSTS:Journal of Semiconductor Technology and Science
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• 제13권3호
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• pp.185-192
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• 2013

In this paper, a clock and data recovery (CDR) circuit that supports triple data rates of 1.62, 2.7, and 5.4 Gbps for DisplayPort 1.2 standard is described. The proposed CDR circuit covers three different operating frequencies with a single VCO switching the operating frequency by the 3-bit digital code. The prototype chip has been designed and verified using a 65 nm CMOS technology. The recovered-clock jitter with the data rates of 1.62/2.7/5.4 Gbps at $2^{31}$-1 PRBS is measured to 7/5.6/4.7 $ps_{rms}$, respectively, while consuming 11 mW from a 1.2 V supply.

• Archives of Pharmacal Research
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• 제29권4호
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• pp.339-342
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• 2006

A simple high performance liquid chromatographic (HPLC) method was developed for the determination of tolperisone in human plasma. Tolperisone and internal standard (chlorphenesin) were isolated from 1 mL of plasma using 8 mL of dichlormethane. The organic phase was collected and evaporated under nitrogen gas. The residue was then reconstituted with 300 mL aliquot of mobile phase and a 100 mL aliquot was injected onto the $C_{18}$ reverse-phased column. The mobile phase, $45\%$ methanol containing $1\%$ glacial acetic acid and $0.05\%$ 1-hexanesulfonic acid was run at a flow rate of 1 mL/min. The column effluent was monitored using UV detector at 260 nm. The retention times for tolperisone and the internal standard were approximately 7.1 and 8.4 min, respectively. The standard curve was linear with minimal intra-day and inter-day variability. The quantification limit of tolperisone in human plasma was 10 ng/ mL. The proposed method has been applied to the determination of pharmacokinetic profile of tolperisone in Koreans. The T max of tolperisone in Koreans $(0.94{\pm}0.42\;h)$ was not significantly differ from that reported in Europeans (0.5-1 h), but the mean half-life in Koreans $(1.14{\pm}0.27\;h)$ was shorter than that in Europeans $(2.56{\pm}0.2\;h)$. The proposed HPLC method is simple, accurate, reproducible and suitable for pharmacokinetic study of tolperisone.