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In Vitro Anticancer Activities of Anogeissus latifolia, Terminalia bellerica, Acacia catechu and Moringa oleiferna Indian Plants

  • Diab, Kawthar AE;Guru, Santosh Kumar;Bhushan, Shashi;Saxena, Ajit K
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.15
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    • pp.6423-6428
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    • 2015
  • The present study was designed to evaluate in vitro anti-proliferative potential of extracts from four Indian medicinal plants, namely Anogeissus latifolia, Terminalia bellerica, Acacia catechu and Moringa oleiferna. Their cytotoxicity was tested in nine human cancer cell lines, including cancers of lung (A549), prostate (PC-3), breast (T47D and MCF-7), colon (HCT-16 and Colo-205) and leukemia (THP-1, HL-60 and K562) by using SRB and MTT assays. The findings showed that the selected plant extracts inhibited the cell proliferation of nine human cancer cell lines in a concentration dependent manner. The extracts inhibited cell viability of leukemia HL-60 and K562 cells by blocking G0/G1 phase of the cell cycle. Interestingly, A. catechu extract at $100{\mu}g/mL$ induced G2/M arrest in K562 cells. DNA fragmentation analysis displayed the appearance of a smear pattern of cell necrosis upon agarose gel electrophoresis after incubation of HL-60 cells with these extracts for 24h.

Efficient Blue Light Emitting Diode by Using Anthracene Derivative with 3,5-Diphenylphenyl Wings at 9- and 10-Position

  • Kim, Yun-Hi;Lee, Sung-Joong;Jung, Sang-Yun;Byeon, Ki-Nam;Kim, Jeong-Sik;Shin, Sung-Chul;Kwon, Soon-Ki
    • Bulletin of the Korean Chemical Society
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    • v.28 no.3
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    • pp.443-446
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    • 2007
  • The novel blue light emitting material, 9,10-bis(3',5'-diphenylphenyl)anthracene (BDA) was synthesized by Suzuki coupling reaction and characterized by the measurements of 1H NMR, 13C NMR and FT-IR. The new anthracene derivative, which contains anthracene as a main core unit and 3',5'-diphenylphenyl group derivative as wings, has high fluorescence yield, good thermal stability, and high glass transition temperature at 188 oC. With the newly non-doped blue emitting material in the multilayer device structure, it was possible to achieve the current efficiency of 3.0 cd/A. The EL spectrum of the ITO/CuPc/α-NPD/BDA/Alq3/LiF/Al device showed a maximum wavelength (λmax) at 440 nm. The emitting color of device showed the blue emission (x,y) = (0.18,0.19) at 10 mA/cm2 in CIE (Commission Internationale de l'Eclairage) chromaticity coordinates.

Raman O VI Profile Analysis of Accretion and Bipoloar Outflow in Sanduleak's Star

  • Heo, Jeong-Eun;Angeloni, Rodolfo;Di Mille, Francesco;Palma, Tali;Lee, Hee-Won
    • The Bulletin of The Korean Astronomical Society
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    • v.42 no.1
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    • pp.58.4-59
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    • 2017
  • Sanduleak's star is a suspected symbiotic binary located in the Large Magellanic Cloud. It is known that it has a giant jet with physical size ~ 14pc. Its spectrum shows two strong emission bands at $6825{\AA}$ and $7082{\AA}$, which are originated from Raman-scattering of O VI by neutral hydrogen atoms. We present the high-resolution spectrum of Sanudleak's star obtained with MIKE at the Magellan-Caly telescope to investigate the O VI emission region based on the profiles of the two Raman features. In this spectrum, it is noted that the Raman $6825{\AA}$ feature exhibits a single broad peak profile, which is in high contrast with a clear triple peak profile of the Raman $7082{\AA}$ feature. In our analysis we suggest that the O VI emission region consist of three main emission parts: an accretion disk, a bipolar outflow and an optically thick, compact component surrounding the white dwarf. By performing Monte Carlo simulation we constrain the representative column density of the H I scattering region N_HI ~1${\times}$10^23 cm^-2, which is in accordance with the observed flux ratio in the two Raman features F(6825)/F(7082) ~ 4.5.

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A Study on the Subjectivity of the Elderly who Live Alone Caregivers in Perception of Lonely Death (독거노인돌보미의 고독사 인식에 관한 주관성 연구)

  • Kwon, Mi Hyoung;Kwon, Young Eun
    • Korean Journal of Adult Nursing
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    • v.24 no.6
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    • pp.647-658
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    • 2012
  • Purpose: This study was to analyzed the types of subjectivity that elderly who live alone caregivers have about the lonely death. Methods: This study objectified the subjective area by applying the Q methodology. It studied 24 caregivers in H region, who responded to 34 Q sample statements. The method of forced distribution was practiced regarding the results on a 9 points Q sample distribution chart. The collected data was analyzed using PC QUANL program. Results: The caregivers' perception of lonely death has been classified into four types: Type 1 ('type of fate-receptive invitation of lonely death'), Type 2 ('type of afterlife-expectantly invitation of lonely death'), Type 3 ('type of death preparation invitation of lonely death'), and type 4 ('type of rejection of lonely death due to attachment with life'). Conclusion: The present study attempts to provide basic resources for the development of nursing-intervention program to solve the problems with lonely death by grasping and understanding the types of the caregivers' perception of lonely death through which it also aims to yield information necessary to improve the quality of life in their remaining years.

Design and Fabrication of Low-Power, High-Frequency, High-Performance Magnetic Thin Film Transformer (저전력, 고주파, 고효율 자성박막 변압기 설계 및 제작에 대한 연구)

  • Yun, Ui-Jung;Jeong, Myeong-Hui
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.50 no.11
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    • pp.555-561
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    • 2001
  • In this paper, the low power (1.5 W) solenoid-type magnetic thin-film transformers utilizing a $Ni_{81}Fe_{19)$ core material were designed and fabricated for 5 MHz-drive DC-DC converter application. The $20\mum$ thick copper films were used as the coils. The transformers fabricated in this work have the sizes of $3.08 mm\times25.5 mm\; and\; 6.15 mm\times12.75 mm.$ The optimum design of solenoid-type magnetic thin film transformers was performed utilizing the conventional equations, a Maxwell computer simulator (Ansoft HFSS V7.0 for PC), and parameters obtained from the magnetic properties of NiFe magnetic core materials. frequency characteristics of inductance, dc resistance (R), coupling factor (k) and gain of developed transformers were measured using HP4194A impedance and gain-phase analyzer. The fabricated transformers with the size of $6.15 mm\time12.75 mm$ exhibit the inductance of $0.83 \muH$, the dc resistance of $2.3\Omega$$\Omega$, the k of 0.91 and the gain of -1 dB at 5 MHz, which show the comparable results to those reported in the recent literatures. The measured high-frequency characteristics for the fabricated transformers agreed well with those obtained by theoretical calculations .

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Physical Function of Patients with Amyotrophic Lateral Sclerosis (근위축성측삭경화증 환자의 신체적 기능 상태)

  • Lee, Yoon-Kyoung;Lim, Nan-Young;Kim, Seung-Hyun
    • Journal of muscle and joint health
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    • v.13 no.2
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    • pp.130-139
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    • 2006
  • Purpose: This study was designed to present preliminary data for the development of appropriate nursing care system for the patients with ALS by analyzing their physical function. Method: The clinical data of 36 ALS patients, who visited ALS Clinic of H University Hospital in Seoul, were collected from January, 2006 to August, 2006. To determine the physical function, Norris ALS scale and Appel ALS Rating Scale were used. The data were analyzed by frequency, percentage, mean, standard deviation, range, t-test, ANOVA, using SPSS PC program. Results: The mean score of physical activity, muscle strength, upper extremity function, lower extremity function was 18.08, 27.72, 25.94, 25.19 respectively. There were significant differences in physical activity, muscle strength, and upper extremity function according to sender and comorbid disease(diabetes). Although sites of symptom onset were not statistically significant with all physical function, patients with bulbar onset showed relatively severe physical disabilities. Conclusion: The preliminary data on physical function of patients with ALS would be helpful for the development of ALS nursing guideline system.

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The Comparison of Characteristics of Foot pressure between Treadmill and Ground walking in Normal person (정상인의 평지보행과 트레드밀 보행 시 족저압의 특성 비교)

  • Kim, Ji-Hye;Oh, Tae-Young
    • Journal of the Korean Society of Physical Medicine
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    • v.5 no.1
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    • pp.53-61
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    • 2010
  • Purpose : The purpose of this study is to compare the distribution of foot pressure, knee and ankle joint angle between treadmill walking and ground walking in normal person. Methods : 18 Person of subject has participated this study, let subject to walk in ground and treadmill in order to gain data of foot distribution and knee, ankle joint angle using by parotec system. and Dartfish system. Walking velocity was constrained by 2Km/h and more 10sec. Date analysis was used by paired-t test using SPSS/PC statistical programs for window. Results : Result show that total contact times has shown symmetry between both legs, and more increase of left foot pressure in treadmill walking. Foot pressure of treadmill walking was significantly decreased in right hind foot and fore foot and hallux area. The ankle joint angle of treadmill walking was significantly decreased in initial contact phase. Conclusion : Results of this study show that foot pressure of treadmill walking was more decreased than ground walking in right hind foot and fore foot, hallux area. And the ankle joint angle of treadmill walking was significantly decreased in initial contact phase.

A Study on Fabrication of Magnetic Thin Film Inductors for DC-DC Converter

  • Lee, Young-Ae;Kim, Sang-Gi;Do, Seung-Woo;Lee, Yong-Hyun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.02a
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    • pp.225-225
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    • 2010
  • In this study, the optimum structure of a magnetic thin film inductor was designed for application of DC-DC converters. The $Ni_{81}Fe_{19}$ (at%) alloy was selected as a high-frequency($\geq$ MHz) magnetic thin film core material and deposited on various substrates (bare Si, $SiO_2$ coated Si) using a high vacuum RF magnetron sputtering system. As-deposited NiFe thin films show similar magnetic properties compared to bulk NiFe alloys, indicating that they have a good film quality. The optimum design of solenoid-type magnetic thin film inductors was performed utilizing a Maxwell computer simulator (Ansoft HFSS V7.0 for PC) and parameters obtained from the magnetic properties of magnetic core materials selected. The high-frequency characteristics of the inductance(L) and quality factor(Q) obtained for the designed inductors through simulation agreed well with those obtained by theoretical calculations, confirming that the simulated result is realistic. The optimum structure of high-performance ($Q{\geq}60$, $L\;=\;1{\mu}H$, efficiency${\geq}90%$), high-frequency (${\geq}5MHz$), and solenoid-type magnetic thin film inductors was designed successfully.

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Algorithm for Discrimination of Brown Rice Kernels Using Machine Vision

  • C.S. Hwang;Noh, S.H.;Lee, J.W.
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 1996.06c
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    • pp.823-833
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    • 1996
  • An ultimate purpose of this study is to develop an automatic brown rice quality inspection system using image processing technique. In this study emphasis was put on developing an algorithm for discriminating the brown rice kernels depending on their external quality with a color image processing system equipped with an adaptor for magnifying the input image and optical fiber for oblique illumination. Primarily , geometrical and optical features of sample images were analyzed with unhulled paddy and various brown rice kernel samples such as sound, cracked, green-transparent , green-opaque, colored, white-opaque and brokens. Secondary, an algorithm for discrimination of the rice kernels in static state was developed on the basis of the geometrical and optical parameters screened by a statistical analysis(STEPWISE and DISCRIM Procedure, SAS ver.6). Brown rice samples could be discriminated by the algorithm developed in this study with an accuracy of 90% to 96% for the sound , cracked, colored, broken and unhulled , about 81% for the green-transparent and the white-opaque and about 75% for the green-opaque, respectively. A total computing time required for classification was about 100 seconds/1000 kernels with the PC 80486-DX2, 66MHz.

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Cosmological Origin of Satellites around Isolated Dwarf Galaxies

  • Chun, Kyungwon;Shin, Jihye;Smith, Rory;Kim, Sungsoo S.
    • The Bulletin of The Korean Astronomical Society
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    • v.44 no.2
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    • pp.39.1-39.1
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    • 2019
  • We trace the cosmological origin of satellites around isolated dwarf galaxies using a very high resolution (12 pc/h) cosmological hydrodynamic zoom simulation. To realistically describe the formation and evolution of small-mass stellar satellites, our model includes a full baryonic physics treatment. We find that the mini-halos form objects resembling dwarf galaxies. The majority of their star forming gas is accreted after reionization, thus the survival of a mini-halo's gas to reionization is not an important factor. Instead, the key factor seems to be the ability for a mini-halo to cool its recently accreted gas, which is more efficient in more massive halos. Although the host galaxy is only a dwarf galaxy itself, we find that ram pressure is an efficient means by which accreted mini-halos lose their gas content, both by interacting with hot halo gas but also in direct collisions with the gas disk of the host. The satellites are also disrupted by the tidal forces near the center of the host galaxy. Compared to the disrupted satellites, surviving satellites are relatively more massive, but tend to infall later into the host galaxy, thus reducing the time they are subjected to destructive environmental mechanisms and dynamical friction.

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