• Title/Summary/Keyword: hMG

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Study on the Skin Absorption of the Organic Solvents (유기용제의 피부흡수 연구)

  • Kim, Hyeon-Yeong;Chung, Yeong-Hyen;Jeong, Jae-Hwang;Sur, Gil-Soo;Moon, Young-Han
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.7 no.2
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    • pp.279-288
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    • 1997
  • The penetrating speeds of organic solvents into the nude mouse skin were measured by in vitro methods(diffusion cell methods) and in vivo methods(measuring internal residues of the organic solvents). The results were as follows: 1. The penetrating speeds of toluene, m-xylene, MEK, MIBK, ethanol, IPA and 2-bromopropane into the skin were $0.4832mg/cm^2/h$, $0.1738mg/cm^2/h$, $1.124mg/cm^2/h$, $0.6627mg/cm^2/h$, $1.747mg/cm^2/h$, $1.359mg/cm^2/h$, and 2-bromopropane $4.165mg/cm^2/h$ respectively. 2. The penetrating speeds of the mixtures of two, toluene and m-xylene, the mixture of three, IPA, ethyl acetate, and MIBK, the mixture of five, toluene, m-xylene, IPA, ethyl acetate, and MIBK were $0.172mg/cm^2/h$, $1.431mg/cm^2/h$, and $2.983mg/cm^2/h$ respectively. 3. The absorption speeds of 2-bromopropane and styrene which were measured by in vivo processes were $3.12mg/cm^2/h$ and $1.44mg/cm^2/h$ respectively. The absorption speed of 2-bromopropane mesured in vivo was 74.9% of that measured by in vitro methods, $4.165mg/cm^2/h$.

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Hydrogen Desorption and Absorption Properties of MgH2, LiBH4, and MgH2 + LiBH4 Composite

  • Park, Hye Ryoung;Song, Myoung Youp
    • Korean Journal of Metals and Materials
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    • v.50 no.12
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    • pp.955-959
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    • 2012
  • To increase the hydrogen storage capacity of Mg-based materials, a sample with a composition of 69.7 wt% $MgH_2$ + 30.3 wt% $LiBH_4$ was prepared by planetary ball milling under hydrogen. The absorption and desorption properties of unmilled $MgH_2$, unmilled $LiBH_4$, and 69.7 wt% $MgH_2$ + 30.3 wt% $LiBH_4$ were examined. At 648 K the unmilled $MgH_2$ desorbed 5.70 wt% for 60 min. The unmilled $LiBH_4$ desorbed 6.40 wt% H for 780 min at 673 K. The 69.7 wt% $MgH_2$ + 30.3 wt% $LiBH_4$ sample desorbed 3.10 wt% H for 50 min, and 3.32 wt% H for 300 min at 623 K at the second cycle.

The Study on the Wear-Corrosion Behavior of Al-Mg Alloy in the Coast (연안해안에서 Al-Mg 합금재 프로펠러의 마멸-부식거동에 관한 연구)

  • Park Hee-Ok;Lim Uh-Joh;Park Dong-Gi
    • Tribology and Lubricants
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    • v.20 no.2
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    • pp.97-101
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    • 2004
  • This paper reports the studies on the wear-corrosion behavior of Al-Mg alloy in various pH environments. In various pH of sea water, corrosion and wear-corrosion loss of Al-Mg alloy were investigated. Also, the polarization test of Al-Mg alloy using potentiostat/galvanostat was carried out. And the rubbed surface of Al-Mg alloy using scanning electron micrographs after wear-corrosion test was examined in various pH values of sea water. The main results are as following : The polarization resistance of Al-Mg alloy in pH 4 solution is higer than that in pH 6.7 solution, and the corrosion current density in pH 4 is controlled than in pH 6.7 solution. The wear-corrosion loss of Al-Mg alloy with lowering pH becomes sensitive. As the oxide product of Al-Mg alloy appears granular structure and exholiation phenomenon, wear-corrosion loss of Al-Mg alloy increases.

Effects of Neuroleptics on the Opioid Receptor Binding in the Mouse Striatum (마우스 선조체에서 Opioid 수용체 결합에 대한 Neuroleptics의 영향)

  • Kim, Soo-Kyung;Lee, Seong-Ryong;Park, Chang-Gyo
    • The Korean Journal of Pharmacology
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    • v.30 no.3
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    • pp.291-297
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    • 1994
  • Our purpose was to gain insight into a possible modulatory role for ${\mu},\;{\delta},\;and\;{\kappa}$ opioid receptors by neuroleptics (chlorpromazine, thioridazine, haloperidol, sulpiride, and pimozide) in chronic morphine 5 mg/kg and 20 mg/kg treated mouse striatum. We attempted quantitative receptor assays using highly specific radioligands, $[^3H]\;DAGO\;([D-Ala^2,\;N-Mephe^4,\;Glycol^5]\;enkephalin)$, $[^3H]DPDPE\;([D-Pen^2,\;D-Pen^5]\;enkephalin)$ and $[^3H]\;DPN(diprenorphine)$ to measure the binding affinity in the experimental groups. The decrease of $[^3H]DAGO$ binding was potentiated by sulpiride and pimozide in the chronic morphine treatment (5 mg/kg and 20 mg/kg). The decrease of $[^3H]DPDPE$ binding was inhibited by chlorpromazine, thioridazine, haloperidol, sulpiride, and pimozide in chronic morphine treatment (5 mg/kg and 20 mg/kg). The decrease of $[^3H]\;DPN$ binding was significantly inhibited by chlorpromazine, thioridazine, sulpiride, and pimozide in chronic morphine 20 mg/kg treatment. $[^3H]\;DPN$ binding on the neuroleptics was antagonized by naloxone pretreatment in chronic morphine 20 mg/kg treatment. These findings suggest that neuroleptics influence opposing tonically active on the ${\delta},\;and\;{\kappa}$ opioid receptor compared with ${\mu}$ opioid receptor in the chronic morphine treated mouse striatum.

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Stabilization of Residual Heavy Metals after Soil Washing of Mine Tailings Contaminated with Arsenic and Heavy Metals (비소와 중금속으로 오염된 광미의 토양세척 후 잔류 중금속의 안정화 처리)

  • Lim, Mihee;Kim, Myoung-Jin
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.1
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    • pp.67-73
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    • 2014
  • In this study, the residual heavy metals in the mine tailings, primarily treated by soil washing, were stabilized using phosphate salts. The concentrations of residual contaminants in the washed mine tailings were As (1,861 mg/kg), Cd (20 mg/kg), Cu (56 mg/kg), Pb (2,149 mg/kg), and Zn (633 mg/kg). They were stabilized with $CaHPO_4$, $Ca(H_2PO_4)_2{\cdot}H_2O$, and hydroxyapatite at 0.1 wt%, 1 wt%, and 10 wt% for 1, 3, 5, 7, and 14 days. It was found that 1 wt% $Ca(H_2PO_4)_2{\cdot}H_2O$ was optimum in our experiments, but the stabilization duration did not affect the efficiency. After stabilization with 1 wt% $Ca(H_2PO_4)_2{\cdot}H_2O$ for 1 day, the concentrations of arsenic and heavy metals, As (0.328 mg/L), Cd (0.250 mg/L), Cu (0.143 mg/L), Pb (0.359 mg/L), and Zn (2.622 mg/L), in TCLP leachate were below the RCRA-TCLP limits, which meant the contaminants in the treated mine tailings were stably immobilized.

Removal of Aqueous Cyanide through the Utilization of Industrial By-products (산업부산물(제강 Sludge, 제강 Slag)을 이용한 시안 흡착 제거)

  • 이정원;현재혁;조재범
    • Journal of Korea Soil Environment Society
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    • v.3 no.2
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    • pp.89-99
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    • 1998
  • Sorption of the aqueous cyanide onto steel mill sludge and steel mill slag, both of which are the by-products from the converter furnace, was studied. In the study, the influence of temperature, activation energy, concentration and pH on sorption of cyanide was investigated. Three different temperature($25^{\circ}C$ > $37^{\circ}C$> $50^{\circ}C$) was chosen to represent that of landfill leachate. Initial concentration was 1 mg/$\ell$ 5 mg/$\ell$, 10 mg/$\ell$, and 20 mg/$\ell$. In addition, pH was set to three different level, that is, 3, 7, and 11 respectively. As the result of batch mode experiment for cyanide adsorption, the removal rate was found to be proportional to the initial concentration of cyanide. The order of removal rate was 20 mg/$\ell$> 10 mg/$\ell$> 5 mg/$\ell$> 1 mg/$\ell$. Similarly the influence of pH was proportional because of the change in solubility of cyanide. The order of removal rate was pH 11 > pH 7 > pH 3. As the temperature increased, so did the removal rate. The reaction was endothermic and the value of activation energy(Ea) was 127.93 J/mole and 59.44 J/mole respectively at 1 mg/ιand 20 mg/ιof initial concentration. From the experiment, it can be postulated that the capability of steel mill by-products to attenuate aqueous cyanide is enough to be used as substitute for clay liner of landfill site in the aspect of pollutant removal.

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Treatment of Wastewater Containing Phenol Using Pseudomonassp. B3 (Pseudomonas sp. B3를 이용한 Phenol 함유 폐수의 처리)

  • 강선태;김정목
    • KSBB Journal
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    • v.11 no.4
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    • pp.476-480
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    • 1996
  • Using Pseudomonas sp. B3, identified and isolated from nature, wastewater containing phenol was treated in a continuous stirred tank reactor and its reaction characteristics were studied. Average concentrations of phenol and COD in effluents were 1.5mg/L and 124mg/L at 0.059h-1 dilution rate, respectively. At the dilution rate higher than 0.063h-1, phenol and COD increased abruptly to 19mg/L and 318mg/L. At the dilution rate higher than 0.059h-1, biomass concentration suddenly decreased and was "washed out". Biomass concentration was 150mg/L at a dilution rate of 0.067h-1. Maximum biomass production rate was 15.98mg/L$.$h at a dilution rate of 0.067h-1. When dilution rate increased above 0.059h-1, effluent phenol concentration abruptly increased and biomass production rate decreased. Maximum cell growth rate(${\mu}$max) and Michaelis-Mentens kinetic constant(Ks) were 0.074h-1 and 0.424mg/L, respectively. From the above result low phenol concentration can be expected at a maximum dilution rate, but reactor becomes unstable due to phenol inhibition.

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Effects of Simulated Acid Rain on Mineral Nutrient Movement in Soil (인공산성비 처리가 토양의 무기양분 이동에 미치는 영향)

  • Ryu, Kwan-Shig
    • Korean Journal of Environmental Agriculture
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    • v.17 no.4
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    • pp.362-367
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    • 1998
  • To investigate the effects of simulated acid rain(SAR) on the downward movement of mineral nutrients, SARs of different pH were applied to the soil. SAR of pH 2.0 decreased the soil pH greatly, while SAR of pH 4.0 and 6.0 did not change the soil pH to compare to that of SAR of pH 2.0. Decrease in soil pH was in the order of sandy loam > loam > clay loam. The amoumt of leached exchangeable and soluble bases from the soil due to the penetration of SAR was in the order of Ca >Mg > K. After application of 1200mm SAR of pH 2.0 in to the soil downward mean movements of the exchangeable and soluble bases was in the order of Mg > Ca > K in sandy loam and loam soil and Ca > Mg > K in clay loam soil. Downward movements of the those bases under pH 4.0 into the soil was in the order of Mg > K > Ca in sandy loam and clay loam, and K > Mg > Ca in loam soil. Available phosphorus moved slightly downward with increasing acidity of the SAR.

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Clomid/hMG/hCG Regimen or FSH/hMG/hCG Regimen : Differences in The Luteal Phase Serum Estradiol and Progesterone Levels Determined after In Vitro Fertilization (시험관아기 프로그램에서 과배란유도 약제의 종류에 따른 황체기 혈청 난포호르몬 및 황체호르몬의 변동에 관한 비교연구)

  • Chang, Yoon-Seok;Shin, Chang-Jae;Kim, Jung-Gu;Moon, Shin-Yong;Lee, Jin-Yong;Kim, Hak-Soon
    • Clinical and Experimental Reproductive Medicine
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    • v.16 no.1
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    • pp.69-79
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    • 1989
  • Steroid hormone profiles during luteal phase of clomiphene citrate(CC)/human menopausal gonadotropin(hMG)/human chorionic gonadotropin(hCG)-stimulated in vitro fertilization (IVF) cycles and of follicle-stimulating hormone(FSH)/hMG/hCG-stimulated IVF cycles were compared. In seventy three cycles stimulated with CC/hMG/hCG regimen, follicles were aspirated during exploratory laparotomy and yielded 7 pregnancies, and in 83 cycles stimulated with FSH/hMG/hCG regimen, follicles were aspirated by laparoscope and made 13 pregnancies. Serum estradiol($E_2$) and progesterone($P_4$) levels were determined on days 2, 5, 7, and 9 after follicle aspiration. The FSH/hMG/hCG regimen was more effective than the CC/hMG/hCG regimen in folliculogenesis, ie, ovarian stimulation, follicular phase $E_2$ peak levels, oocyte maturation, and the number of retrieved oocytes. There was no significant difference between luteal serum $P_4/E_2$ ratio of the two regimens, suggesting that secretory endometrial build-up ability for implantation may not differ each other. Several significant correlations were observed between follicular phase seum $E_2$ peak levels and luteal phase serum $E_2$ and $P_4$ levels in the FSH/hMG/hCG-stimulated cycles but any correlation was not significant in the CC/hMG/hCG-stimulated cycles, suggesting that somewhat more follicles may eventually fall in atresia even after attaining dominant stage in the CC/hMG/hCG-stimulated cycles than the FSH/hMG/hCG-stimulated cycles.

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Synthesis of Sub-Micron MgH2 using Hydriding Thermal Chemical Vapor Synthesis (수소화기상증착공정을 이용한 마그네슘하이드라이드 미세분말 합성)

  • Kang, Taehee;Kim, Jinho;Han, Kyusung;Kim, Byunggoan
    • Transactions of the Korean hydrogen and new energy society
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    • v.23 no.5
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    • pp.455-460
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    • 2012
  • This work describes the hydriding chemical vapor synthesis (HCVS) of the $MgH_2$ in a hydrogen atmosphere and the product's hydriding-dehydridng properties. Mg powder was used as a starting material to synthesize $MgH_2$ and uniformly heated to a temperature of $600^{\circ}C$ for Mg vaporization. The effects of hydrogen pressure on the morphology and the composition of HCVS-$MgH_2$ were examined by using X-ray diffraction (XRD) and scanning electron microscopy (SEM). It is clearly seen that after the HCVS process, the particle size of synthesized $MgH_2$ was drastically reduced to the submicron or micrometer-scale and these showed different shapes (needle-like nanofibers and angulated plate) depending on the hydrogen pressure. It was found that after the HCVS process, the $H_2$ desorption temperature of HCVS-$MgH_2$ decreased from 380 to $410^{\circ}C$, and the minimum hydrogen desorption tempreature of HCVS-$MgH_2$ powder with needle-like shape can be obtained. In addition, the enhanced hydrogen storage performance for needle-like $MgH_2$ was achieved during subsequent hydriding-dehydriding cycles.