• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.6 no.1
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• pp.1-9
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• 2003

Purpose: To investigate the relation of the gastric epithelial cell proliferation, apoptosis and genotypes of H. pylori in children. Methods: Histologic grading by updated Sydney system, PCNA immunostaining, TUNEL method and the genotypes (cagA, picB and iceA) by PCR were performed in H. pylori positive (N=20) and negative (N=20) gastric biopsy specimens. Results: PCNA index was significantly different between H. pylori positive children ($77.4{\pm}13.12$) and H. pylori negative children ($52.3{\pm}12.20$) (p=0.000). There were positive correlations between PCNA index and H. pylori density (r=0.624, p=0.000), polymorphonuclear neutrophil activity (r=0.460, p=0.005) and chronic inflammation (r=0.433, p=0.009). Apoptosis index of H. pylori positive children ($0.70{\pm}0.411$) was significantly higher than of H. pylori negative children ($0.14{\pm}0.201$) (p=0.000). Positive correlations between apoptosis index and H. pylori density (r=0.691, p=0.000), polymorphonuclear neutrophil activity (r=0.585, p=0.000) and chronic inflammation (r=0.535, p=0.001) were noted. As PCNA index increased, apoptosis index significantly increased (r=0.527, p=0.001). The positive rates of genotypes were cagA 90%, picB 75%, iceA1 60% and iceA2 15%, respectively. There were no significant correlations between the status of the genotypes and PCNA index, apoptosis index, the endoscopic findings and the histologic findings. Conclusion: PCNA index and apoptosis index in H. pylori positive children were higher than in H. pylori negative children but were not related to H. pylori genotypes. This study suggested that correlatively increased gastric epithelial cell proliferation and apoptosis are important to pathogenesis of H. pylori infection in children.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2008.06a
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• pp.313-314
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• 2008

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.2819-2822
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• 2013

In this study, antiproliferative effects of the selective estrogen receptor modulator Tamoxifen and the aromatase inhibitor letrozole (Femara) were evaluated and compared using the FM3A cell line, originating from a C3H mouse mammary carcinoma and positive in terms of estrogen receptor (ER) expression. Cell kinetic parameters including labelling index, mitotic index and labelling index were assessed after exposure of the. FM3A cell line to $0.001{\mu}g/ml$ of Tamoxifen and $0.25{\mu}g/ml$ of Femara for 4, 8, 16 and 32 h for all parameters. The results showed that cell growth was inhibited by both agents. There was a significant decrease in labelling index and mitotic index and significant increase in apoptotic index for all experimental groups. The differences between control and all experimental groups were statistically significant (p<0.001) for all applications.

• Asian-Australasian Journal of Animal Sciences
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• v.5 no.4
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• pp.737-740
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• 1992

This study was conducted to demonstrate the practical use of the buffer index curve as a criterion of silage quality evaluation, Forty five samples of the ensiled Italian ryegrass were collected from farms in Okayama, Japan. Silages were devided into 4 groups by the pattern of buffer index curve. Heavy wilting silages (A group) showed no peak on buffer index curve and Flieg's score of 95.6. However, moderate or weak wilting silages (B group) with moisture content of 63.3 showed a peak at pH 4.0 and a Flieg's score of 67.8. Both of A and B groups were regarded as a good quality silage. Silages (C group) with a peak at pH 4.5 were of a medium quality with Flieg's score of 45.3. Poorly preserved silages (D group) with Flieg's score of 12.0 had a peak at pH 5.0. There was a high positive correlationship (p<0.01) between the peak value of buffer index curve and the organic acid content.

• Proceedings of the Korean Society for Information Management Conference
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• 2011.08a
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• pp.29-34
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• 2011

최근 인용 네트워크 분석을 통해서 단일 문헌의 인용 영향력을 측정하려는 시도가 다양하게 전개되고 있다. 널리 알려진 PageRank를 보완하려는 일부 시도와 함께 h-index를 단일 문헌의 인용 영향력 측정에 적용한 단일문헌 h-index도 제안되었다. 이 연구에서는 Web of Science에서 검색한 계량정보학 분야 문헌집합을 대상으로 여러 측정 방식의 특징을 비교해본 후, 새로운 인용지수 2종을 제안하였다. 제안한 인용지수는 PageRank처럼 전역 네트워크 분석 방식인 지수 1종과 h-index처럼 지역 네트워크 분석 방식인 지수 1종으로서 상황에 따라 선택하여 사용할 수 있다.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.29A no.3
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• pp.8-14
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• 1992

In this paper, the differential detection technique of multi-h CPM is introduced and described. We derived the sets of modulation index of multi-h phase codes adequate to the differential detection. The power spectra of multi-h signals with various sets of modulation index are presented and compared to those of MSK and QPSK. Error rate performances of the conventional detector and Viterbi algorithm detector of 2-h and 3-h CPM are evaluated and compared.

• Korean Journal of Plant Resources
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• v.23 no.2
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• pp.172-178
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• 2010

This study was carried out to investigate abiotic and biotic environmental factors affecting homoharringtonine (HHT) contents of Cephalotaxus koreana, whereby, to provide basic information of high value-added industry production of HHT as a promising anti-cancer agent. For correlation between abiotic environmental factors (soil moisture, soil pH, habitat density and temperature) and HHT contents, the contents were highly correlated with soil moisture (0.77) and soil pH (-0.68). For multiple regression analysis of relationship between abiotic environmental factors (soil moisture and soil pH) and HHT contents, soil moisture appeared to be strongly affecting the contents relatively due to being significant at only its regression coefficient ($26.48^{***}$). For the effect of biotic environmental factors (damage index) affecting HHT contents, the contents was quadratic with equation of $H=278.23+1242D-398.87D^2$, also, damage index had strong effect on the contents. Finally, for the result of the most influencing an environmental factor on HHT contents, both damage index and soil moisture were suitable in second polynomial regression, also, damage index ($R^2=0.73^{***}$) was turned out to be more influencing factor than soil moisture ($R^2=0.67^{**}$) on HHT contents relatively. Therefore, we predict that HHT contents in the trees of Cephalotaxus koreana is produced as a chemical defense mechanism triggered by a stress-related damage of fungi or insects.

• Korean Journal of Veterinary Research
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• v.56 no.3
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• pp.133-137
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• 2016

Changes in the cardiovascular and bispectral index score were evaluated in dogs subjected to constant rate infusion (CRI) with alfaxalone. Fifteen dogs were assigned to three groups of 5. Groups and doses of alfaxalone were as follows: group 1, 3 mg/kg for induction and 6 mg/kg/h for CRI; group 2, 3 mg/kg for induction and 8 mg/kg/h for CRI; and group 3, 3 mg/kg for induction and 10 mg/kg/h for CRI. CRI was maintained for 1 h. Respiratory rates and blood pressures showed minimal changes; however, mild tachycardia and mild hypoxemia occurred, especially in group 3. There were some disparities between bispectral index score, electromyography and pedal withdrawal reflex test when measuring anesthetic depth. Additional premedications and/or analgesic agents would be helpful to avoid adverse effects of alfaxalone and provide improved cardiopulmonary functions.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.67 no.3
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• pp.374-382
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• 2018

This paper has done a hardware-based approach to increase the modulation index in 3-phase inverters, unlike the conventional software algorithm-based approaches. The minimum required time to measure the currents in a three-phase inverters with shunt resistors has also been analyzed. By the analysis, the longest time in minimum required time is AD conversion time. To shorten the minimum required time, this paper proposed a sample-and-hold(S/H) circuit implemented at the inverter current signal output to retain the current signal. When the linear operation region of an inverter with S/H was compared with that without it, the modulation index was increased by 7.8 %. Inverters with S/H circuits can employ the traditional software algorithms, such as the voltage injection method or current restoration method, and it will yield further increase the modulation index.

• Speech Sciences
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• v.4 no.1
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• pp.113-133
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• 1998

The system proposed in this paper prosodically transcribes the intonation patterns, prosodic structures, phrasings, and other prosodic aspects of Korean utterances, on four parallel tiers: a tone tier, an orthographic tier, a break index tier, and a miscellaneous tier. The tone tier employs two phrase accents (L* and H *), three accentual phrase boundary tones (L-, H-, LH-), and four intonational phrase boundary tones (L%,H%,LH%,LHL%) in order to provide a phonological transcription of pitch events associated with accented syllables and phrase boundaries. The break index tier uses five break indices, numbered from 0 to 4, which mark a prosodic grouping of words and its prosodic structure in an utterance. Among the five indices, the break index 3 and the break index 4 align with an accentual phrase boundary tone and an intonational phrase boundary tone, respectively, in the tone tier.