• Journal of Korean Neurosurgical Society
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• v.57 no.4
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• pp.276-282
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• 2015

Objective : The purpose of this study was to investigate morphological change at the craniovertebral junction (CVJ) region using computed tomography. Methods : A total of 238 patients were included in this study, and mean age was $47.8{\pm}21.3months$. Spinal canal diameter, Power's ratio, McRae line, antero-posterior C1 ring height, atlantoaxial joint space, C2 growth, epidural space from the dens (M-PB-C2) and longitudinal distance (basion to C2 lower margin, B-C2) were measured. The mean value of each parameter was assessed for individual age groups. The cohorts were then divided into three larger age groups : infancy (I) (${\leq}2years$), very early (VE) childhood (2-5 years) and early (E) childhood ($5{\geq}years$). Results : Spinal canal diameter increased with age; however, this value did not increase with statistical significance after VE age. A significant age-related difference was found for all C2 body and odontoid parameters (p<0.05). Mean McRae line was 8.5, 8, and 7.5 mm in the I, VE, and E groups, respectively. The M-PB-C2 line showed up-and-down dynamic change during early pediatric periods. Conclusion : Expansion of the spinal canal was restricted to the very early childhood period (less than 5 years) in the CVJ region; however, the C2 body and odontoid process increased continuously with age. The above results induced a dynamic change in the M-PB-C2 line. Although C2 longitudinal growth continued with age, the McRae line showed relatively little change.

• Biotechnology and Bioprocess Engineering:BBE
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• v.11 no.4
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• pp.351-356
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• 2006

This study developed an artificial neural network (ANN) to estimate the growth of microorganisms during a fermentation process. The ANN relies solely on the cumulative consumption of alkali and the buffer capacity, which were measured on-line from the on/off control signal and pH values through automatic pH control. The two input variables were monitored on-line from a series of different batch cultivations and used to train the ANN to estimate biomass. The ANN was refined by optimizing the network structure and by adopting various algorithms for its training. The software estimator successfully generated growth profiles that showed good agreement with the measured biomass of separate batch cultures carried out between at 25 and $35^{\circ}C$.

• Journal of Ginseng Research
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• v.17 no.3
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• pp.196-202
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• 1993

A study was performed to compare the anticancer effects of Korean and Chinese red ginseng roots. The whole crude extracts or chloroform, methanol and acetone fractions of the crude extracts were added in the culture medium of three cancer cell lines, a mouse leukemia cell line ($P_{388}$), a human colon carcinoma cell line (HT-29) and a human rectal carcinoma cell line (HRT-18), to screen the growth inhibition effects. The results are summarized as follows : 1. Crude extracts of both Korean and Chinese red ginseng roots inhibited the proliferation of all the three cancer cell lines tested in a dose dependent manner. However, the growth inhibition effects of Korean red ginseng extracts were significantly greater than that of Chinese red ginseng. 2. An acetone fraction showed the greatest antiproliferative effects among the 11'hole crude extracts, chloroform, methanol and acetone fractions of the crude extracts. 3. These results suggest that the active antiproliferative components of the crude extracts are present mostly in the acetone fraction.

• Applied Microscopy
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• v.44 no.2
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• pp.74-78
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• 2014

Dislocation density and distribution in epitaxial GaAs layer on Si are evaluated quantitatively and effectively using image processing of transmission electron microscopy image. In order to evaluate dislocation density and distribution, three methods are introduced based on line-intercept, line-length measurement and our coding with line-scanning method. Our coding method based on line-scanning is used to detect the dislocations line-by-line effectively by sweeping a thin line with the width of one pixel. The proposed method has advances in the evaluation of dislocation density and distribution. Dislocations can be detected automatically and continuously by a sweeping line in the code. Variation of dislocation density in epitaxial GaAs films can be precisely analyzed along the growth direction on the film.

• International Commerce and Information Review
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• v.9 no.4
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• pp.91-104
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• 2007

The recent stabilization of the Internet is now driving every aspect of life into an Internet presence. In the coming years, the Internet will see growth in numbers unlike the world has ever seen. The subject of this study is the Research Study on the Products Purchase Type of On-line Shopping Mall Buyer. Also, this paper is to examine the relations between customer satisfaction and intensity of repurchase intention and complaining behavior in on-line context. On-line shopping customer depths interview it led and the online afternotes trust evaluation dimension was discovered the of useful characteristic, intention characteristic, exaggerating characteristic and on-line afternotes with or without. From these results, this paper suggests effective marketing strategy to the marketer who plans to run on-line shopping mall in the near future and also to the marketer who plans to sell products through the on-line shopping mall.

• KSBB Journal
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• v.7 no.2
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• pp.96-101
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• 1992

A low serum medium(LSM) suitable for the growth of a self-constructed hybridoma cell line, KA112, was established by selecting ingredients to replace serum. Insulin and sodium pyruvate was important for the growth of cell line KA112. Various basal media were tested and DMEM gave the most favorable result. Low serum medium (LSM) developed in this work showed cell line stability in the culture for more than 6 months and exhibited cell growth equivalent to that carried out in medium supplemented with 7% FBS. LSM was found to be applicable to the suspension culture of KA112. The reduction of serum level down to 1%(V/V) FBS in LSM resulted in a substantial saving in the cost of media preparation for large scale culture.

• KSBB Journal
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• v.27 no.3
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• pp.186-194
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• 2012

Various human host cell lines, which are more effective than the other original human cell lines, have been developed and used. Highly efficient human cell line can be obtained from the fusion between human embryonic kidney 293 (HEK293) and human Burkitt's lymphoma cells (Namalwa). Fused cell line has the advantages of both cell lines such as the high transfection efficacy of HEK293 cells and the constitutive expression of Epstein-Barr virus (EBV) genome which is related with high expression of target protein and anti-apoptotic growth of Namalwa cells. In this study, characterization of two original cell lines was performed by using design of experiment (DOE) considering cell maintenance, media development, optimization of culture condition, and scale-up. The formation of aggregates was apparent with high glutamine concentration at more than 6 mM. Supplementation of hydrolysates showed positive effects on the growth performances of HEK293 cells. On the contrary, Namalwa cells showed negative results. It was confirmed that Namalwa cells were more sensitive to lower temperature at $35^{\circ}C$ and hyperosmotic condition over 260 mOsm/kg. In addition, both cell lines showed limited growth in 3-L bioreactor due to shear stress.

• Progress in Superconductivity and Cryogenics
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• v.1 no.1
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• pp.1-6
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• 1999

The microstructures of top seed mult processde $\textrm{YBa}_2\textrm{Cu}_3\textrm{O}_7$.$\delta$ single crystal were studied. Although shape of the seed was not faceted. the growth shape of Y123 single crystal was faceted. It was observed that Y211 phases were trapped in specific spaces of the faceted region. From the microstructural investigation. it was suggested that the segregation of Y211 is due to the difference of growth rates in crystal direction. When a single crystal was grown by the single seed with stepped multi surfaces. a microstrue was grown from multi-seed. The microstructure show the possibility of multi-seed growth. Corn kernel like structure without Y211 phase was observed and seemed to be formed by the diffusion reaction between Y211 phase in crystal and liquid wetted on the crystal. the diagonal line on Y123 crystal was observed that it was formed by the corn kernel like structure.

• International Journal of Precision Engineering and Manufacturing
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• v.3 no.2
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• pp.95-101
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• 2002

The propagation rate(da/dt) prediction parameter and the microstructure properties of creep crack in domestic 3.3NiCrMov steel were investigated at 550$\^{C}$ by using 0.5" CT specimen under constant load(4090N) and constant Ct(300∼4000N/mhr) condition that was maintained during crack growth of 1mm distance. C＊ usually increased with crack length though load was reduced in order to maintain constant Ct value as crack growth and considerably showed the scatter band, but Ct depended on load line displacement rate and represented a good relation with da/dt. At constant toad and Ct region, crack growth slope was 0.900 and 0.844 each, in the other hand C＊ slope was 0.480. Fully coalesced area(FCA) ahead of crack tip was increased as Ct value increase to the critical value, and after that value FCA decreased. The average diameter ditribution of cavity in FCA showed the greatest value about 1.5 ㎛ when Ct=2000N/mhr. The increasing of Ct in FCA view point enlarged the size of damage area and the size reached to maximum 800 ㎛ when Ct=2000N/mhr.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.15 no.9
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• pp.711-717
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• 2003

This paper presents the effects of the fin array and pitch on the frost layer growth of a heat exchanger. The numerical results are compared with experimental data of a cold plate to validate the present model, and agree well with experimental data within a maximum error of 8%. The frost behaviors of the staggered fin array are somewhat different from those of in-line array. The frost layer formed on the first fin of the in-line array grows rapidly, compared to second fin, whereas the difference of the frost layer growth between the fins of the staggered array is small. For fin pitch below 10 m, the frost layer growth of second fin in the staggered array is affected by that of first fin. The thickness of the frost layer and heat transfer of single fin are reduced with decreasing fin pitch regardless of fin array. However, the thermal performance of a heat exchanger is enhanced due to the increase of heat transfer surface area.