• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 추계학술대회
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• pp.798-803
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• 2003

The objective of the present study is to investigate the changes in the acoustic source characteristics and far-field noise propagation in an incompressible round jet at Re=10000 for single-frequency excitations using large eddy simulation and Lighthill acoustic analogy. We apply excitations at a frequency corresponding to the jet-column mode ($St_{D}=0.85$) or maximum growth rate in the shear layer ( $St_{\theta}=0.017$ ). The acoustic source derived from the Lighthill acoustic analogy is the second spatial derivative of the Reynolds stresses. In the case of $St_{D}=0.85$, vortex ring and large scale structures are dominant sources, whereas in the case of $St_{\theta}=0.017$, the main sources are located at an upstream position along the shear layer than in the uncontrolled case. Also, the far-field noise propagates along the axial direction due to excitation.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.113-117
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• 1997

In this paper we detected the thrombosis formation by spectral analysis and neural network. Using microphone and amplifier, we measured the sound from the mechanical valve which is attached to the pneumatic ventricular assist device. The sound was sampled by A/D converter and the periodogram is the main algorithm or obtaining spectrum. We made the valvular thrombosis models using pellethane and silicon and they are thrombosis model on the disk, around the sewing ring and fibrous tissue growth across the orifice of valve. The spectrum of normal and 5 kinds of thrombotic valve were obtained and primary and secondary peak appeared in each spectrum waveform. So to distinguish the secondary peak of normal and thrombotic valve quantatively, 3 layer back propagation neural network.

• Journal of the Korean Wood Science and Technology
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• 제2권2호
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• pp.4-4
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• 1974

본 보고는 1952년 1월부터 3월중순까지 약 50일간에 걸쳐 FAO주최하에 개최된 극동 임업 기술자 강습회에 출석시 마레이 반도산 중요 목재 즉 열대성 유용목재에 대하여 그 해부학적 특징을 연구한 결과이다. 남방 열대산 목재는 대부분이 활엽수이며 그 특이한 점은 온대수목에서 조성되는 연륜은 볼 수 없고 그 대신 생장륜(growth ring)을 가지는 점과 특히 유조직(parenchyma)이 발달되고 있는 점을 들 수 있다. 남방재의 재질은 강한 것이 많고 그 목리(grain)는 대개는 교착목리(interlocked grain)로 되어서 미려한 무늬(figure)를 나타내는 것이 많으므로 기구재로서 많이 애용되고 있다. 주로 관찰된 육안 및 렌스(X10)에 의한 해부학적 성질은 재색, 광택, 무늬, 목리, 경도, 비중, 도관의 배열, 도관의 크기, 도관의 수, 도관내의 함유물질, 유조직의 배열, 방사조직의 수 및 크기였다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2003년도 춘계학술대회 논문집 기술교육전문연구회
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• pp.31-34
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• 2003

The sapphire wafers for blue light emitting devices were manufactured by the implementation of the surface machining technology based on micro-tribology. This process has been performed by chemical and mechanical polishing(CMP) process. The sapphire crystalline wafers were characterized by double crystal X-ray diffraction. The sample quality of sapphire crystalline wafer at surfaces has a full width at half maximum 89 arcses. The surfaces of sapphire wafers were mechanically affected by residual stress and surface default. Sapphire wafers's waveness has higher abrasion rate in the edge of the wafer than its center due to Newton's Ring interference.

• Bulletin of the Korean Chemical Society
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• 제34권11호
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• pp.3317-3321
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• 2013

A series of new 3-alkylamino-6-allylthio-pyridazine derivatives was synthesized through allythiolation and amino-de-halogenation and were expected to have anti-proliferative activity. 6-Allylthio-3-chloropyridazine was prepared from the reaction of 3,6-dichloropyridazine with allylmercaptan and sodium hydroxide. The alkylamines such as methylamine and the dialkylamines such as dimethylamine were introduced into the 3-position of the pyridazine ring. These new compounds showed anti-proliferative activities against MCF-7 human breast cancer cells in CCK-8 assays. These compounds are thus promising candidates for chemotherapy of breast cancer. Two compounds, 14 and 15, showed higher potencies for inhibiting growth of breast cancer cells than did 5FU. This suggests the potential anti-proliferative activity of these compounds.

• 대한기계학회논문집A
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• 제28권1호
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• pp.85-91
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• 2004

The sapphire wafers for blue light emitting devices were manufactured by the implementation of the surface machining technology based on micro-tribology. This process has been performed by chemical and mechanical polishing process. The sapphire crystalline wafers were characterized by double crystal X-ray diffraction. The sample quality of sapphire crystalline wafer at surfaces has a full width at half maximum of 89 arcsec. The surfaces of sapphire wafer were mechanically affected by residual stress during the polishing process. The wave pattern of optical interference of sapphire wafer implies higher abrasion rate in the edge of the wafer than its center from the Newton's ring.

• 한국분말야금학회:학술대회논문집
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• 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part2
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• pp.1319-1320
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• 2006

Several practical applications of melt-textured bulk superconductors require the complex-shaped products such as curved, ring-shaped, and drilled blocks rather than simple shaped pellets. However, melt-textured bulk superconductors are often damaged when they are cut, grinded, or drilled. With the aim of reducing such damages, we have investigated the preparation of the complex-shaped bulk superconductors by previously machining binder-added precursors and pre-sintered precursors. We could produce various complex-shaped bulk superconductors without cracking from these machined precursors

• 한국제4기학회지
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• 제6권1호
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• pp.21-32
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• 1992

The paleoclimate of the Chungbu Mountainous Region, Mts. Seorak and Sobaek, was estimated by means of dendroclimatic methodology, The annual growth value of tree-rings is deeply interrelated with the mean temperature of April-May and July-August. The mean temperature of April-May of the reconstruction period(1635-1911), observation period(1912-1989), and the whole period(1635-1989) is 13.58$^{\circ}C$, 13.69$^{\circ}C$, and 13.6$0^{\circ}C$, respectively. That of July-August is $24.50^{\circ}C$, $24.62^{\circ}C$, and $24.58^{\circ}C$ respectively. The reconstructed mean temperature data for April-May and for July-August reveal 13.2 and 12.9 year cycles.

• Bulletin of the Korean Chemical Society
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• 제26권6호
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• pp.959-965
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• 2005

Investigation of structure-activity relationships of novel quinazolines has identified 7,8-dihydro-[1,4]dioxino-[2,3-g]quinazolines as a potent inhibitor of EGFR. These compounds have a benzodioxane framwork, which was prepared by regioselective O-alkylation of ethyl 3,4-dihydroxy benzoate by epoxide ring opening. Compounds 3f and 3k were more potent than ZD-1839 in EGF enzyme and EGFR autophosporylation inhibition assays.

• Bulletin of the Korean Chemical Society
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• 제30권1호
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• pp.83-91
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• 2009

To develop new anticancer agents, 3-allylthio-6-aminopyridazine derivatives were synthesized from maleic anhydrides or phthalic anhydrides by formation of a pyridazine nucleus, dichlorination, allylthiolation and amination. The pyridazine nuclei were obtained by condensing a hydrazine monohydrate with maleic anhydride. An allylthio group as a pharmacologically active group was introduced into one side of a pyridazine ring. Arylalkylamines with benzene or pyridine moieties or heterocycloalkylamines with heterocycle moieties such as morpholine, piperidine, or pyrrolidine were also introduced into the para-position of allylthio pyridazine. These new compounds showed antiproliferative activities against SK-Hep-1 human liver cancer cells in MTT assays. These compounds are thus promising candidates for chemotherapy of hepatocellular carcinomas. Two compounds, 20c and 22a, showed higher potencies for inhibiting growth of hepatocellular carcinoma cells than did K6 ($ID_50$=1.08 mM). This suggests the potential anticancer activity of these two compounds.