• Title/Summary/Keyword: growth retardation

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CASE REPORTS RUSSELL-SILVER SYNDROME (증례 보고 : Russell-Silver Syndrome)

  • Lee, Jin;Jang, Ki-Taeg;Kim, Chong-Chul
    • Journal of the korean academy of Pediatric Dentistry
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    • v.29 no.1
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    • pp.51-56
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    • 2002
  • Russell-Silver syndrome is a type of intrauterine growth retardation, characterized by short stature noted at birth, hemiatrophy or asymmetry, variation in sexual development and other abnormalities, including cafe-aulait pigmentation and clinodactyly. Facial features commonly associated with this syndrome are a small triangular face, decreased facial height, down-turned corners of the mouth(shark's mouth), a small mandible, and occasionally asymmetry. The major intra-oral features of the syndrome that have been reported are a high-arched palate, delayed tooth eruption, microdontia, hypodontia, and crowding. These cases were diagnosed at birth as Russell-Silver syndrome by clinical features such as prenatal growth retardation, short stature, low body weight, et al., and have been treated with growth hormone. The purpose of this paper is to report the dental findings of two patients and review the pertinent literature through the two cases.

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Studies on the Effects of the Pine Needle Gall Midge, Thecodiplosis japonensis Uchida et Inouye, on the Growth of the Red Pine, Pinus densiflora S. et Z. (II) - Growth impact on red pine - (솔잎혹파리가 소나무생장(生長)에 미치는 영향(影響)에 관한 연구(研究)(II) - 소나무의 피해(被害) -)

  • Park, Ki Nam;Hyun, Jai Sun
    • Journal of Korean Society of Forest Science
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    • v.62 no.1
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    • pp.87-95
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    • 1983
  • The effects of the pine needle gall midge, Thecodiplosis japonensis, on the growth of the Korean red pine, Pinus densiflora, were examined for the natural forest stands at nine locations: Seocheon-gun, Boryong-gun, and Hongseong-gun in Chooncheongnam-do, where consequence of the infestation had been different. To estimate the economic threshold level of the pine needle gall midge, the growth impacts due to the insect were examined with terminal shoot growth, and cambial growth by analyzing the growth horizontally and vertically. The results obtained are as follows: 1) In general, the growth impacts of the red pine trees were significant for the five consecutive years since damage had occurred, and its maximum retardation was shown in the second and the third years. 2) Simultaneous retardation occurred in both terminal and cambial growth of the tree, probably due to cumulative characteristics of the feeding behaviour. 3) Strong correlation was found between terminal and cambial growth of Korean red pine and this was true for the trees infested by pine needle gall midge. Thus retardation in cambial growth due to the insect may be estimated with that in terminal growth. 4) Infestation was greater on slope facing north than south even though the history of the infestation had been similar. 5) The stem volume of 13-year-old, infested Korean red pine was reduced by more than 75-85%, compared to same aged, uninfected pine in yield table. Thus, much longer period is required to recover the normal growth.

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The Use of Compliance to Investigate Fatigue Crack Retardation by Cover Plates and Stop Hole Expansion (컴프라이언스를 이용한 보강판재와 균열선단 구멍확장의 피로균열 진전 지연효과 규명)

  • 한문식
    • Transactions of the Korean Society of Automotive Engineers
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    • v.9 no.4
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    • pp.204-213
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    • 2001
  • This paper develops the compliance approach to the problem of load sharing between a cracked plate and a cover plate used to bridge the crack. The theory is validated by using calculated stress intensity factors for the covered and uncovered cases and by using stop hole method to reduce experimentally observed growth rates to a common base. Calculations are then made on the effect of cover plate width on fatigue crack retardation in order to demonstrate the predictive capability of the technique.

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Effects of Strain Hardening Exponents on the Retardation of Fatigue Crack Propagation (가공경화지수가 피로균열 지연거동에 끼치는 영향)

  • 김상철;강동명
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.14 no.5
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    • pp.1193-1199
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    • 1990
  • Effects of strain hardening exponents on the behavior of fatigue crack propagation are experimentally investigated. The retardation effect of fatigue crack propagation after single overloading is investigated in relation to strain hardening exponent and crack closure. A relationship between crack opening ratio and strain hardening exponents is inspected through an examination of the crack closure behavior. An empirical equation relating retardation effect of fatigue crack propagation after single overloading, percent peak load and strain hardening exponent of materials is proposed.

An evaluation of Fatigue Crack Propagation Behaviors on Cyclic Overload Test (반복과대하중에 의한 피로파괴거동의 고찰)

  • 김용수;신근하;강동명;김병석
    • Journal of the Korean Society of Safety
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    • v.7 no.2
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    • pp.47-56
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    • 1992
  • The retardation effect of fatigue crack propagation after cyclic overloading seems to be affected by strain hardening exponent. Namely, for the material with high values of n, the delay effect is found to be severe. We proposed a modified crack retardation equation which may apply the retardation of fatigue crack growth after a cyclic overloading, as (da/dN)'$_{cyc}$=($\mu$n+λ)B $\Delta$ $K^{q}$ /[(1- $R_{eff}$) $K_{cf}$$\Delta$K]. where, $R_{eff}$ is effective stress ratio [=( $K_{min}$-K, os)/( $K_{max}$$K_{res}$)] The constants $\mu$=-0.5 and λ=0.6, and the values are found to be identical for materials such as aluminum (A 1060), steel (SS 34), brass ( $B_{s}$ SIB) and stainless steel (SUS 304) used in this investigation. (SUS 304) used in this investigation.ation.n.n.

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Changes of the growth plate in children: 3-dimensional magnetic resonance imaging analysis

  • Yun, Hyung Ho;Kim, Hyun-Jung;Jeong, Min-Sun;Choi, Yun-Sun;Seo, Ji-Young
    • Clinical and Experimental Pediatrics
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    • v.61 no.7
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    • pp.226-230
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    • 2018
  • Purpose: This pilot study assessed changes in the growth plate and growth rates in children during a 6-month period. Methods: The study included 31 healthy children (17 boys, 14 girls) under evaluation for growth retardation. Height, weight, bone age, insulin like growth factor-1 (IGF-1), and insulin like growth factor binding protein 3 (IGF-BP3) were measured at baseline and after 6 months. In addition, the diameter, thickness, and volume of the femoral and tibial growth plates were measured using magnetic resonance imaging. Results: The mean bone age in boys and girls was 11.7 and 10.7 years, respectively. In boys, height (z score) (-0.2 vs. 0.0), weight (z score) (0.8 vs. 1.1), body mass index (BMI) (z score) (1.27 vs. 1.5), IGF-1 (ng/mL) (343.6 vs. 501.8), and IGF-BP3 (ng/mL) (5,088.5 vs. 5,620.0) were significantly higher after 6 months. In girls, height (z score) (-1.0 vs. -0.7), weight (z score) (-0.5 vs. 0.1), BMI (z score) (-0.02 vs. 0.3), IGF-1 (ng/mL) (329.3 vs. 524.6), and IGF-BP3 (ng/mL) (4,644.4 vs. 5,593.6) were also significantly higher after 6 months. In both sexes, the mean diameter and volume of the femoral and tibial growth plates were significantly increased 6 months later. Conclusion: No significant correlation was found between changes in the growth plate and clinical parameters in children with growth retardation in this study, other than correlations of change in femoral diameter with weight and BMI. A larger, long-term study is needed to precisely evaluate the correlation between change in the growth plate and growth.

Characterization of Soluble Dietary Fibers from Wax Gourd (Benincasa hispida) Pulp and Peel

  • Hong, Sun-Pyo;Jun, Hyun-Il;Song, Geun-Seoup;Kwon, Yong-Ju;Kim, Young-Soo
    • Food Science and Biotechnology
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    • v.17 no.4
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    • pp.734-738
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    • 2008
  • The physicochemical and in vitro physiological properties of soluble dietary fiber (SDF) from wax gourd (Benincasa hispida) pulp and peel were investigated. The pulp was composed of 11.4% SDF and 24.3% insoluble dietary fiber (IDF), while the peel contained 3.2% SDF and 43.3% IDE The predominant sugar in the SDF of the wax gourd pulp and peel was uronic acid, followed by galactose and rhamnose. The SDFs from the wax gourd pulp and peel gave similar elution patterns, with 4 main neutral sugar and uronic acid peaks eluted by 0.4, 0.5, 1, and 2 M ammonium acetate buffer. The pulp SDF had a much higher glucose retardation index (GRI) than the peel SDF for all measurement times. The pulp SDF showed strong growth-inhibiting activity against Escherichia coli and Clostridium perfringens, whereas the peel SDF produced strong growth-promoting activity against Bifidobacterium longum, Bifidobacterium infantis, and Lactobacillus brevis when compared to glucose.

Neonatal Silver-Russell syndrome assumed to result from maternal uniparental heterodisomy of chromosome 7

  • Kang, Yoongu;Kim, Jinsup;Lee, Hyun Ju;Park, Hyun Kyung
    • Journal of Genetic Medicine
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    • v.17 no.2
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    • pp.83-88
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    • 2020
  • Silver-Russell syndrome (SRS) is a rare genetic disorder characterized by intrauterine growth restriction, poor postnatal growth, relative macrocephaly, a triangular face, body asymmetry, and feeding difficulties. It is primarily diagnosed according to a clinical scoring system; however, the clinical diagnosis is confirmed with molecular testing, and the disease is stratified into the specific molecular subtypes. SRS is a genetically heterogeneous condition. The major molecular changes are hypomethylation of imprinting control region 1 in 11p15.5 and maternal uniparental disomy of chromosome 7 (UPD(7)mat). Therefore, first-line molecular testing should include methylation-specific approaches for these regions. Here, we report an extremely low birth weight (ELBW) infant with intrauterine growth retardation, postnatal growth retardation, and dysmorphic facial appearance-characteristics consistent with the clinical diagnostic criteria of SRS. Methylation-specific molecular genetic analysis revealed UPD(7)mat, while the loss of heterozygosity was not detected on chromosomal microarray analysis. We present a case of SRS with suspected uniparental heterodisomy of chromosome 7 in an ELBW infant.

Effect of mach peening treatment on fatigue crack growth retardation in structural steel alloy (마하피닝 처리에 의한 기계구조용 합금강의 피로균열전파 지연효과)

  • Kim, Min-Gun;Lim, Bok-Kyu;Park, Hong-Ki;Hwang, Jung-Gak
    • Journal of Industrial Technology
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    • v.26 no.A
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    • pp.69-73
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    • 2006
  • Mach peening treatment is one of the various kinds of techniques to improve the fatigue properties. The mach peening process gives high-level work hardening and compressive residual stress near the surface layer, improving the fatigue strength. In addition, this treatment reduces slip bands that initiate the fatigue cracks near the surface. During impingement, a plastic indentation surrounded by a plastic zone is formed. Mach peening treatment characteristic is less energy consumption and is an environmental friendly processing methods that is not accompanied by pollution. It is machining process that can prevent fatigue fracture beforehand in structure using already as well as process of production. The test results showed that fatigue crack propagation delay appeared by drilling type 43%, mach peening type 110%.

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Fracture Mechanics Analysis of Multiple Load Path Plate (다중 균열 보강 판재에 관한 파괴 역학적 해석)

  • Han, Moon-Sik;Lee, Yang-Sub
    • Journal of the Korean Society for Precision Engineering
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    • v.18 no.10
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    • pp.109-115
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    • 2001
  • The compliance approach to the problem of load sharing between a cracked plate and multiple plate used to bridge the crack. The theory is validated by using calculated stress intensity factors for the multiple load path plate to reduce experimentally observed growth rate to a common base. Calculations are them made on the effect of multiple load path plate width on fatigue crack retardation in order to demonstrate the predictive capability of the technique.

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